Hei tauira, he heremaia pūtau toronaihi tētahi mate iranga tangata e puta mai ana i tētahi rerekētanga pūtake kotahi i roto i te rohe waeherenga mō te wāhanga β-globin o te hemoglobin, nāna tētahi huringa waikawa amino kotahi e huri ai i ngā āhuatanga ōkiko o te hemoglobin.