# Seth J. Orlow, M.D., Ph.D.

Professor; Samuel Weinberg Professor of Pediatric Dermatology; Derm Dir Pgrm Cutaneous Bio NYU Cancer Skn; Chair Ronald O Perelman Derm   
Ronald O. Perelman Department of Dermatology (Fac) [1],  Cell Biology (Cell Biology) [2] and  Pediatrics (Administration) [3]   
NYU Dermatologic Associates  
  


## Clinical Addresses

530 FIRST AVENUE  
NEW YORK, NY 10016  
**Handicap Access:** yes  
**Phone:** 212-263-5889  
**Fax:** 212-263-7680  


### Medical Specialties

Pediatric Dermatology, Dermatology 

### Medical Expertise

Pediatric/Adolescent Dermatology, Genetic Skin Diseases, Skin Malignancies/Hemangiomas 

### Languages

French 

### Board Certification

1990 — Ab Dermatology - Dermatology   
2004 — Ab Dermatology (Pediatric Dermatology)   


### Education

1986 — Albert Einstein College of Medicine, Medical Education   
1986-1987 — Mount Sinai Medical Center (Pediatrics), Internship   
1987-1989 — Yale - New Haven Medical Center (Dermatology), Residency Training   
1989-1990 — Yale - New Haven Medical Center (Pediatric Dermatology), Clinical Fellowships   


### Research Summary

1\. Development of novel therapeutics for the treatment of a number of cancers including melanoma and multiple myeloma, as well as unraveling pathways underlying chemoresistance in these tumors. To do so, we utilize small molecule screening of already-approved drugs ("drug repositioning") and of natural products combined with molecular and cellular techniques. 2\. Understanding the cell biology of melanin synthesis and deposition in the skin, hair and eyes, including the processing and trafficking of tyrosinase, the rate-limiting enzyme in melanin production, as well as the pathogenesis of various forms of oculocutaneous albinism that diminish pigmentation. 3\. Elucidating the pathogenesis of vitiligo, in which melanocytes in the skin are destroyed, including the role of endoplasmic reticulum stress and the unfolded protein response. 

### Research Interests

Development of Novel Targeted Therapeies in Melanoma and other Cancers; Molecular and Cellular Basis of Pigmentation 

### Research Keywords

eye color, genetics, melanosomes, membrane glycoproteins, pigmentation 

**Contact:**  
http://hsl.med.nyu.edu/faculty-bibliography-search [11]  


**Identification of agents that promote endoplasmic reticulum stress using an assay that monitors luciferase secretion**  
 _Doudican, Nicole A; Wen, Shih Ya; Mazumder, Amitabha; Orlow, Seth J_  
2014 Apr;19(4):575-584, Journal of biomolecular screening  
— id: 836082, year: 2014, vol: 19, page: 575, stat: Journal Article, 

**Cole disease results from mutations in ENPP1**  
 _Eytan, O.; Monce-Picard, F.; Sarig, O.; Nousbeck, J.; Ezzedine, K.; Isakov, O.; Li, Q.; Ishida-Yamamoto, A.; Shomron, N.; Goldsmith, T.; Adir, N.; Uitto, J.; Orlow, S. J.; Taieb, A.; Sprecher, E._  
2014 MAY;134 1 1:S73-S73, Journal of investigative dermatology  
— id: 997152, year: 2014, vol: 134 1 1, page: S73, stat: Journal Article, 

**The cutaneous microbiota in atopic dermatitis changes with topical corticosteroid and bleach bath treatment**  
 _Gonzalez, M. E.; Schaffer, J. V.; Orlow, S. J.; Gao, Z.; Li, H.; Alekseyenko, A. V.; Blaser, M. J._  
2014 MAY;134 1 1:S109-S109, Journal of investigative dermatology  
— id: 997122, year: 2014, vol: 134 1 1, page: S109, stat: Journal Article, 

**Genital melanocytic nevi in children: Experience in a pediatric dermatology practice**  
 _Hunt, Raegan D; Orlow, Seth J; Schaffer, Julie V_  
2014 Mar;70(3):429-434, Journal of the American Academy of Dermatology  
— id: 811032, year: 2014, vol: 70, page: 429, stat: Journal Article, 

**Mucocutaneous Granulomatous Disease in a Patient With Hermansky-Pudlak Syndrome**  
 _Salvaggio, Heather L; Graeber, Kristen E; Clarke, Loren E; Schlosser, Bethanee J; Orlow, Seth J; Clarke, Jennie T_  
2014 Jul;:1083-1087 e100663, JAMA dermatology  
— id: 1065872, year: 2014, vol: , page: 1083, stat: Journal Article, 

**Neutrophil-rich lymphomatoid papulosis in an adolescent**  
 _Boyd, K P; Gonzalez, M; Orlow, S J; Meehan, S A_  
2013 July 2013;35(5):e95-e95, American journal of dermatopathology  
— id: 550222, year: 2013, vol: 35, page: e95, stat: Journal Article, 

**Loss of Oca2 disrupts the unfolded protein response and increases resistance to endoplasmic reticulum stress in melanocytes**  
 _Cheng, Tsing; Orlow, Seth J; Manga, Prashiela_  
2013 Nov;26(6):826-834, Pigment cell & melanoma research  
— id: 586232, year: 2013, vol: 26, page: 826, stat: Journal Article, 

**XIAP downregulation accompanies mebendazole growth inhibition in melanoma xenografts**  
 _Doudican, Nicole A; Byron, Sara A; Pollock, Pamela M; Orlow, Seth J_  
2013 Oct;:181-188, Anti-cancer drugs  
— id: 179287, year: 2013, vol: , page: 181, stat: Journal Article, 

**Evidence-based recommendations for the diagnosis and treatment of pediatric acne**  
 _Eichenfield, Lawrence F; Krakowski, Andrew C; Piggott, Caroline; Del Rosso, James; Baldwin, Hilary; Friedlander, Sheila Fallon; Levy, Moise; Lucky, Anne; Mancini, Anthony J; Orlow, Seth J; Yan, Albert C; Vaux, Keith K; Webster, Guy; Zaenglein, Andrea L; Thiboutot, Diane M_  
2013 May;131 Suppl 3:S163-S186, Pediatrics  
— id: 370332, year: 2013, vol: 131 Suppl 3, page: S163, stat: Journal Article, 

**Cole Disease Results from Mutations in ENPP1**  
 _Eytan, Ori; Morice-Picard, Fanny; Sarig, Ofer; Ezzedine, Khaled; Isakov, Ofer; Li, Qiaoli; Ishida-Yamamoto, Akemi; Shomron, Noam; Goldsmith, Tomer; Fuchs-Telem, Dana; Adir, Noam; Uitto, Jouni; Orlow, Seth J; Taieb, Alain; Sprecher, Eli_  
2013 Oct;93(4):752-757, American journal of human genetics  
— id: 602862, year: 2013, vol: 93, page: 752, stat: Journal Article, 

**The dermatology foundation: partnerships and programs focused on the future**  
 _Fairley, Janet A; Krueger, Gerald G; Lessin, Stuart R; Leyden, James J; McBurney, Elizabeth I; Orlow, Seth J; Tharp, Michael D; Voorhees, John J; Wintroub, Bruce U; Yancey, Kim B_  
2013 Apr;133(4):861-862, Journal of investigative dermatology  
— id: 255602, year: 2013, vol: 133, page: 861, stat: Journal Article, 

**Cutaneous features of crouzon syndrome with acanthosis nigricans**  
 _Mir, Adnan; Wu, Timothy; Orlow, Seth J_  
2013 Jun;149(6):737-741, JAMA dermatology  
— id: 464262, year: 2013, vol: 149, page: 737, stat: Journal Article, 

**Spitz nevi: beliefs, behaviors, and experiences of pediatric dermatologists**  
 _Tlougan, Brook E; Orlow, Seth J; Schaffer, Julie V_  
2013 Mar;149(3):283-291, JAMA dermatology  
— id: 346462, year: 2013, vol: 149, page: 283, stat: Journal Article, 

**IL-17 and TNF Synergistically Modulate Cytokine Expression while Suppressing Melanogenesis: Potential Relevance to Psoriasis**  
 _Wang, Claire Q F; Akalu, Yemsratch T; Suarez-Farinas, Mayte; Gonzalez, Juana; Mitsui, Hiroshi; Lowes, Michelle A; Orlow, Seth J; Manga, Prashiela; Krueger, James G_  
2013 Dec;133(12):2741-2752, Journal of investigative dermatology  
— id: 666502, year: 2013, vol: 133, page: 2741, stat: Journal Article, 

**Experience With Molluscum Contagiosum and Associated Inflammatory Reactions in a Pediatric Dermatology Practice: The Bump That Rashes**  
 _Berger, Emily M; Orlow, Seth J; Patel, Rishi R; Schaffer, Julie V_  
2012 Aug;:1-8, Archives of dermatology  
— id: 179288, year: 2012, vol: , page: 1, stat: Journal Article, 

**Dysregulation of the unfolded protein response contributes to chemoresistance in melanocytes**  
 _Cheng, T; Orlow, S J; Manga, P_  
2012 May 2012;132:S131-S131, Journal of investigative dermatology  
— id: 166924, year: 2012, vol: 132, page: S131, stat: Journal Article, 

**Identification of the Black Tea Polyphenol Theaflavin-3, 3 '-Digallate From Screen of Natural Product Inducers of Endoplasmic Reticulum Stress**  
 _Doudican, Nicole A.; Wen, Shih Ya; Mazumder, Amitabha; Orlow, Seth J._  
2012 NOV 16;120(21):-, Blood  
— id: 227372, year: 2012, vol: 120, page: , stat: Journal Article, 

**Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells via stress-mediated pathways**  
 _Doudican, Nicole A; Wen, Shih Ya; Mazumder, Amitabha; Orlow, Seth J_  
2012 Nov;28(5):1851-1858, Oncology reports  
— id: 178061, year: 2012, vol: 28, page: 1851, stat: Journal Article, 

**A role for the unfolded protein response in vitiligo**  
 _Manga, P; Toosi, S; Orlow, S J_  
2012 September 2012;25(5):685-686, Pigment cell & melanoma research  
— id: 250132, year: 2012, vol: 25, page: 685, stat: Journal Article, 

**Engineering a new mouse model for vitiligo**  
 _Manga, Prashiela; Orlow, Seth J_  
2012 Jul;132(7):1752-1755, Journal of investigative dermatology  
— id: 169522, year: 2012, vol: 132, page: 1752, stat: Journal Article, 

**Vitiligo inducing phenols increase production of IL6 and IL8 from melanocytes via the unfolded protein response**  
 _Toosi, S; Orlow, S J; Manga, P_  
2012 May 2012;132:S127-S127, Journal of investigative dermatology  
— id: 166925, year: 2012, vol: 132, page: S127, stat: Journal Article, 

**Vitiligo-Inducing Phenols Activate the Unfolded Protein Response in Melanocytes Resulting in Upregulation of IL6 and IL8**  
 _Toosi, Siavash; Orlow, Seth J; Manga, Prashiela_  
2012 Jun;:2601-2609, Journal of investigative dermatology  
— id: 174329, year: 2012, vol: , page: 2601, stat: Journal Article, 

**Melanocyte adaptation to ER stress and activation of the unfolded protein response in Oca2-null melanocytes**  
 _Cheng, T; Orlow, S J; Manga, P_  
2011 August 2011;24(4):810-810, Pigment cell & melanoma research  
— id: 241432, year: 2011, vol: 24, page: 810, stat: Journal Article, 

**Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cell lines through generation of ER stress**  
 _Doudican, N A; Mazumder, A; Orlow, S J_  
2011 18 Nov 2011;118(21):-, Blood  
— id: 169662, year: 2011, vol: 118, page: , stat: Journal Article, 

**Patient-reported outcomes in pediatric patients with psoriasis undergoing etanercept treatment: 12-week results from a phase III randomized controlled trial**  
 _Langley, Richard G; Paller, Amy S; Hebert, Adelaide A; Creamer, Kara; Weng, Haoling H; Jahreis, Angelika; Globe, Denise; Patel, Vaishali; Orlow, Seth J_  
2011 Jan;64(1):64-70, Journal of the American Academy of Dermatology  
— id: 138250, year: 2011, vol: 64, page: 64, stat: Journal Article, 

**Informed reasoning: repositioning of nitisinone to treat oculocutaneous albinism**  
 _Manga, Prashiela; Orlow, Seth J_  
2011 Oct 3;121(10):3828-3831, Journal of clinical investigation  
— id: 141072, year: 2011, vol: 121, page: 3828, stat: Journal Article, 

**Albendazole sensitizes cancer cells to ionizing radiation**  
 _Patel, Kirtesh; Doudican, Nicole A; Schiff, Peter B; Orlow, Seth J_  
2011 ;6:160-160, Radiation oncology  
— id: 145769, year: 2011, vol: 6, page: 160, stat: Journal Article, 

**Radiation therapy for high-risk squamous cell carcinomas in patients with xeroderma pigmentosum: report of two cases and review of the literature**  
 _Schaffer, Julie V; Orlow, Seth J_  
2011 ;223(2):97-103, Dermatology  
— id: 141972, year: 2011, vol: 223, page: 97, stat: Journal Article, 

**Identifying novel therapeutic agents for vitiligo**  
 _Tan, A. U.; Orlow, S. J.; Manga, P._  
2011 APR ;131(5):S121-S121, Journal of investigative dermatology  
— id: 131840, year: 2011, vol: 131, page: S121, stat: Journal Article, 

**Spitz nevi - a pediatric dermatology perspective**  
 _Tlougan, B. E.; Orlow, S. J.; Schaffer, J. V._  
2011 APR ;131(5):S41-S41, Journal of investigative dermatology  
— id: 131837, year: 2011, vol: 131, page: S41, stat: Journal Article, 

**Abortive segmental perineal hemangioma**  
 _Tlougan, Brook E; Gonzalez, Mercedes E; Orlow, Seth J_  
2011 ;17(10):8-8, Dermatology online journal  
— id: 157495, year: 2011, vol: 17, page: 8, stat: Journal Article, 

**Role of oxidative stress and unfolded protein response in development of vitiligo**  
 _Toosi, S.; Orlow, S. J.; Manga, P._  
2011 APR ;131(5):S120-S120, Journal of investigative dermatology  
— id: 131839, year: 2011, vol: 131, page: S120, stat: Journal Article, 

**Fluvastatin Enhances Sorafenib Cytotoxicity in Melanoma Cells via Modulation of AKT and JNK Signaling Pathways**  
 _Zhang, Shali; Doudican, Nicole A; Quay, Ellinor; Orlow, Seth J_  
2011 Oct;31(10):3259-3265, Anticancer research  
— id: 138114, year: 2011, vol: 31, page: 3259, stat: Journal Article, 

**Differential adaptation to chronic ER stress in wildtype and Oca2 melanocytes**  
 _Cheng T.; Manga P.; Bis S.; Knoll K.; Orlow S.S._  
2010 ;23(5):710-710, Pigment cell & melanoma research  
— id: 113676, year: 2010, vol: 23, page: 710, stat: Journal Article, 

**Enhancement of arsenic trioxide cytotoxicity by dietary isothiocyanates in human leukemic cells via a reactive oxygen species-dependent mechanism**  
 _Doudican, Nicole A; Bowling, Benjamin; Orlow, Seth J_  
2010 Feb;34(2):229-234, Leukemia research  
— id: 106489, year: 2010, vol: 34, page: 229, stat: Journal Article, 

**Morphea, diabetes mellitus type I, and celiac disease: case report and review of the literature**  
 _Firoz, Elnaz F; Kamino, Hideko; Lehman, Thomas J A; Orlow, Seth J_  
2010 Jan 1;27(1):48-52, Pediatric dermatology  
— id: 107790, year: 2010, vol: 27, page: 48, stat: Journal Article, 

**Androgenetic alopecia in the paediatric population: a retrospective review of 57 patients**  
 _Gonzalez, M E; Cantatore-Francis, J; Orlow, S J_  
2010 Aug;163(2):378-385, British journal of dermatology  
— id: 111343, year: 2010, vol: 163, page: 378, stat: Journal Article, 

**Delineation of the unfolded protein response in melanocytes: Potential implications for vitiligo and UV response**  
 _Manga P.; Vega M.; Bis S.; Knoll K.; Orlow S._  
2010 ;23(5):704-705, Pigment cell & melanoma research  
— id: 113675, year: 2010, vol: 23, page: 704, stat: Journal Article, 

**The unfolded protein response in melanocytes: activation in response to chemical stressors of the endoplasmic reticulum and tyrosinase misfolding**  
 _Manga, Prashiela; Bis, Sabina; Knoll, Kristen; Perez, Beremis; Orlow, Seth J_  
2010 Oct;23(5):627-634, Pigment cell & melanoma research  
— id: 112422, year: 2010, vol: 23, page: 627, stat: Journal Article, 

**Disulfiram induces copper-dependent stimulation of reactive oxygen species and activation of the extrinsic apoptotic pathway in melanoma**  
 _Morrison, Brian W; Doudican, Nicole A; Patel, Kirtesh R; Orlow, Seth J_  
2010 Feb;20(1):11-20, Melanoma research  
— id: 106093, year: 2010, vol: 20, page: 11, stat: Journal Article, 

**Undifferentiated pleomorphic sarcoma in a child with type 1 neurofibromatosis**  
 _Patel, R R; Meehan, S; Orlow, S J_  
2010 Aug;163(2):431-433, British journal of dermatology  
— id: 111345, year: 2010, vol: 163, page: 431, stat: Journal Article, 

**Lichen planopilaris noted during etanercept therapy in a child with severe psoriasis**  
 _Abbasi, Naheed R; Orlow, Seth J_  
2009 Jan-Feb;26(1):118-118, Pediatric dermatology  
— id: 96935, year: 2009, vol: 26, page: 118, stat: Journal Article, 

**Initiation of the unfolded protein response in melanocytes and melanoma**  
 _Bis, SG; Knoll, KE; Lolis, MS; Orlow, SJ; Manga, P_  
2009 APR ;129(5):S139-S139, Journal of investigative dermatology  
— id: 97878, year: 2009, vol: 129, page: S139, stat: Journal Article, 

**Practical guidelines for evaluation of loose anagen hair syndrome**  
 _Cantatore-Francis, Julie L; Orlow, Seth J_  
2009 Oct;145(10):1123-1128, Archives of dermatology  
— id: 104733, year: 2009, vol: 145, page: 1123, stat: Journal Article, 

**From the rarest to the most common: insights from progeroid syndromes into skin cancer and aging**  
 _Capell, Brian C; Tlougan, Brook E; Orlow, Seth J_  
2009 Oct;129(10):2340-2350, Journal of investigative dermatology  
— id: 102396, year: 2009, vol: 129, page: 2340, stat: Journal Article, 

**Effect of celastrol on temozolomide cytotoxicity in melanoma cells and inhibition of NF-kB signaling**  
 _Chen M.; Osman I.; Orlow S.J._  
2009 ;27(15 Suppl 1):9076-9076, Journal of clinical oncology  
— id: 111808, year: 2009, vol: 27, page: 9076, stat: Journal Article, 

**Antifolate activity of pyrimethamine enhances temozolomide-induced cytotoxicity in melanoma cells**  
 _Chen, Ming; Osman, Iman; Orlow, Seth J_  
2009 May;7(5):703-712, Molecular cancer research  
— id: 99017, year: 2009, vol: 7, page: 703, stat: Journal Article, 

**Celastrol Synergistically Enhances Temozolomide Cytotoxicity in Melanoma Cells**  
 _Chen, Ming; Rose, Amy E; Doudican, Nicole; Osman, Iman; Orlow, Seth J_  
2009 Dec;7(12):1946-1953, Molecular cancer research  
— id: 105467, year: 2009, vol: 7, page: 1946, stat: Journal Article, 

**Effect of mebendazole on melanoma xenograft growth through targeting of bcl-2**  
 _Doudican N.A.; Pennell R.; Tu T.; Liebes L.; Pavlick A.; Berman R.; Shapiro R.; Goldberg J.D.; Osman I.; Orlow S._  
2009 ;27(15 Suppl 1):9075-9075, Journal of clinical oncology  
— id: 111807, year: 2009, vol: 27, page: 9075, stat: Journal Article, 

**Cole disease: guttate hypopigmentation and punctate palmoplantar keratoderma**  
 _Moore, Megan M; Orlow, Seth J; Kamino, Hideko; Wang, Nadia; Schaffer, Julie V_  
2009 Apr;145(4):495-497, Archives of dermatology  
— id: 108282, year: 2009, vol: 145, page: 495, stat: Journal Article, 

**Porokeratotic eccrine ostial and dermal duct nevus: a report of 2 cases and review of the literature**  
 _Wang, Nadia S; Meola, Thomas; Orlow, Seth J; Kamino, Hideko_  
2009 Aug;31(6):582-586, American journal of dermatopathology  
— id: 101127, year: 2009, vol: 31, page: 582, stat: Journal Article, 

**Developing a multidisciplinary prospective melanoma biospecimen repository to advance translational research**  
 _Wich, Lindsay G; Hamilton, Heather K; Shapiro, Richard L; Pavlick, Anna; Berman, Russell S; Polsky, David; Goldberg, Judith D; Hernando, Eva; Manga, Prashiela; Krogsgaard, Michelle; Kamino, Hideko; Darvishian, Farbod; Lee, Peng; Orlow, Seth J; Ostrer, Harry; Bhardwaj, Nina; Osman, Iman_  
2009 ;1(1):35-43, American journal of translational research  
— id: 105566, year: 2009, vol: 1, page: 35, stat: Journal Article, 

**The misnomer "macrocephaly-cutis marmorata telangiectatica congenita syndrome": report of 12 new cases and support for revising the name to macrocephaly-capillary malformations**  
 _Wright, Dakara Rucker; Frieden, Ilona J; Orlow, Seth J; Shin, Helen T; Chamlin, Sarah; Schaffer, Julie V; Paller, Amy S_  
2009 Mar;145(3):287-293, Archives of dermatology  
— id: 107820, year: 2009, vol: 145, page: 287, stat: Journal Article, 

**Inhibition of mitochondrial protein translation sensitizes melanoma cells to arsenic trioxide cytotoxicity via a reactive oxygen species dependent mechanism**  
 _Bowling, Benjamin D; Doudican, Nicole; Manga, Prashiela; Orlow, Seth J_  
2008 Dec;63(1):37-43, Cancer chemotherapy & pharmacology  
— id: 91428, year: 2008, vol: 63, page: 37, stat: Journal Article, 

**Planning for a brighter future: a review of sun protection and barriers to behavioral change in children and adolescents**  
 _Dadlani, Chicky; Orlow, Seth J_  
2008 ;14(9):1-1, Dermatology online journal  
— id: 96936, year: 2008, vol: 14, page: 1, stat: Journal Article, 

**Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells**  
 _Doudican, Nicole; Rodriguez, Adrianna; Osman, Iman; Orlow, Seth J_  
2008 Aug;6(8):1308-1315, Molecular cancer research  
— id: 86657, year: 2008, vol: 6, page: 1308, stat: Journal Article, 

**A role for the pink-eyed dilution protein in tyrosinase folding**  
 _Manga, P; Knoll, K; Fenton, J; Orlow, SJ_  
2008 APR ;21(2):261-262, Pigment cell & melanoma research  
— id: 78651, year: 2008, vol: 21, page: 261, stat: Journal Article, 

**Chemical genetic screening identifies tricyclic compounds that decrease cellular melanin content**  
 _Ni-Komatsu, Li; Orlow, Seth J_  
2008 May;128(5):1236-1247, Journal of investigative dermatology  
— id: 79089, year: 2008, vol: 128, page: 1236, stat: Journal Article, 

**Identification of quinolines that inhibit melanogenesis by altering tyrosinase family trafficking**  
 _Ni-Komatsu, Li; Tong, Chunxiang; Chen, Guangming; Brindzei, Nelya; Orlow, Seth J_  
2008 Dec;74(6):1576-1586, Molecular pharmacology  
— id: 91438, year: 2008, vol: 74, page: 1576, stat: Journal Article, 

**Symmetric truncal aplasia cutis congenita following multifetal reduction of a sextuplet pregnancy**  
 _Schaffer, Julie V; Popiolek, Dorota A; Orlow, Seth J_  
2008 Dec;153(6):860-863, Journal of pediatrics  
— id: 93386, year: 2008, vol: 153, page: 860, stat: Journal Article, 

**Pegylated liposomal doxorubicin (PLD): enhanced skin toxicity in areas of vitiligo**  
 _Yuan, Y; Orlow, Sj; Curtin, J; Downey, A; Muggia, F_  
2008 ;2:111-111, ecancermedicalscience  
— id: 150576, year: 2008, vol: 2, page: 111, stat: Journal Article, 

**Mycophenolate mofetil for severe childhood atopic dermatitis: experience in 14 patients**  
 _Heller, M; Shin, H T; Orlow, S J; Schaffer, J V_  
2007 Jul;157(1):127-132, British journal of dermatology  
— id: 73948, year: 2007, vol: 157, page: 127, stat: Journal Article, 

**Unilateral cutaneous heterotopic meningeal nodules with neural, smooth muscle and connective tissue hamartomas: a field defect of cephalic neural crest-derived tissues**  
 _Hunzeker, C M; Borys, D; Greco, M A; Orlow, S J; Schaffer, J V_  
2007 May;156(5):1047-1050, British journal of dermatology  
— id: 73845, year: 2007, vol: 156, page: 1047, stat: Journal Article, 

**"Pediatric blaschkitis": expanding the spectrum of childhood acquired Blaschko-linear dermatoses**  
 _Keegan, Brian R; Kamino, Hideko; Fangman, William; Shin, Helen T; Orlow, Seth J; Schaffer, Julie V_  
2007 Nov-Dec;24(6):621-627, Pediatric dermatology  
— id: 75486, year: 2007, vol: 24, page: 621, stat: Journal Article, 

**Identification of novel pigmentation modulators by chemical genetic screening**  
 _Ni-Komatsu, Li; Orlow, Seth J_  
2007 Jul;127(7):1585-1592, Journal of investigative dermatology  
— id: 73033, year: 2007, vol: 127, page: 1585, stat: Journal Article, 

**Current concepts in clinical management and long-term control atopic dermatitis : focus on pimecrolimus cream 1% : 11 tables**  
 _Orlow, Seth J_  
Basel : Karger, 2007,   
— id: 1624, year: 2007, vol: , page: , stat: , 

**Topical calcineurin inhibitors in pediatric atopic dermatitis: a critical analysis of current issues**  
 _Orlow, Seth J_  
2007 ;9(5):289-299, Paediatric drugs  
— id: 75476, year: 2007, vol: 9, page: 289, stat: Journal Article, 

**Pigmented plexiform neurofibroma: Distinction from a large congenital melanocytic nevus**  
 _Schaffer, Julie V; Chang, Mary W; Kovich, Olympia I; Kamino, Hideko; Orlow, Seth J_  
2007 May;56(5):862-868, Journal of the American Academy of Dermatology  
— id: 94939, year: 2007, vol: 56, page: 862, stat: Journal Article, 

**Ulcerated haemangioma of infancy: a retrospective review of 47 patients**  
 _Shin, H T; Orlow, S J; Chang, M W_  
2007 May;156(5):1050-1052, British journal of dermatology  
— id: 107821, year: 2007, vol: 156, page: 1050, stat: Journal Article, 

**The ocular albinism type 1 gene product, OA1, spans intracellular membranes 7 times**  
 _Sone, Michio; Orlow, Seth J_  
2007 Dec;85(6):806-816, Experimental eye research  
— id: 76079, year: 2007, vol: 85, page: 806, stat: Journal Article, 

**The physician-scientist**  
 _Chu, David H; Orlow, Seth J_  
2006 Mar;126(3):527-527, Journal of investigative dermatology  
— id: 63076, year: 2006, vol: 126, page: 527, stat: Journal Article, 

**Eccrine angiomatous hamartoma**  
 _Dadlani, Chicky; Orlow, Seth J_  
2006 ;12(5):9-9, Dermatology online journal  
— id: 96937, year: 2006, vol: 12, page: 9, stat: Journal Article, 

**Phacomatosis pigmentokeratotica associated with hemihypertrophy and a rhabdomyosarcoma of the abdominal wall**  
 _Gruson, Lisa M; Orlow, Seth J; Schaffer, Julie V_  
2006 Aug;55(2 Suppl):S16-S20, Journal of the American Academy of Dermatology  
— id: 67008, year: 2006, vol: 55, page: S16, stat: Journal Article, 

**Ehlers-Danlos syndrome type VIII: periodontitis, easy bruising, marfanoid habitus, and distinctive facies**  
 _Moore, Megan M; Votava, Jennie M; Orlow, Seth J; Schaffer, Julie V_  
2006 Aug;55(2 Suppl):S41-S45, Journal of the American Academy of Dermatology  
— id: 96939, year: 2006, vol: 55, page: S41, stat: Journal Article, 

**Heterologous expression of tyrosinase recapitulates the misprocessing and mistrafficking in oculocutaneous albinism type 2: effects of altering intracellular pH and pink-eyed dilution gene expression**  
 _Ni-Komatsu, Li; Orlow, Seth J_  
2006 Mar;82(3):519-528, Experimental eye research  
— id: 63732, year: 2006, vol: 82, page: 519, stat: Journal Article, 

**Mutations in the desmoglein 4 gene underlie localized autosomal recessive hypotrichosis with monilethrix hairs and congenital scalp erosions**  
 _Schaffer, Julie V; Bazzi, Hisham; Vitebsky, Anna; Witkiewicz, Agnieszka; Kovich, Olympia I; Kamino, Hideko; Shapiro, Lawrence S; Amin, Snehal P; Orlow, Seth J; Christiano, Angela M_  
2006 Jun;126(6):1286-1291, Journal of investigative dermatology  
— id: 64666, year: 2006, vol: 126, page: 1286, stat: Journal Article, 

**Mucocutaneous neuromas: an underrecognized manifestation of PTEN hamartoma-tumor syndrome**  
 _Schaffer, Julie V; Kamino, Hideko; Witkiewicz, Agnieszka; McNiff, Jennifer M; Orlow, Seth J_  
2006 May;142(5):625-632, Archives of dermatology  
— id: 64392, year: 2006, vol: 142, page: 625, stat: Journal Article, 

**Ocular albinism 1 protein: trafficking and function when expressed in Saccharomyces cerevisiae**  
 _Staleva, Liliana; Orlow, Seth J_  
2006 Feb;82(2):311-318, Experimental eye research  
— id: 63596, year: 2006, vol: 82, page: 311, stat: Journal Article, 

**Patient perspectives on the management of atopic dermatitis**  
 _Zuberbier, Torsten; Orlow, Seth J; Paller, Amy S; Taieb, Alain; Allen, Roger; Hernanz-Hermosa, Jose M; Ocampo-Candiani, Jorge; Cox, Margaret; Langeraar, Joanne; Simon, Jan C_  
2006 Jul;118(1):226-232, Journal of allergy & clinical immunology  
— id: 96940, year: 2006, vol: 118, page: 226, stat: Journal Article, 

**Consensus statement on the safety profile of topical calcineurin inhibitors**  
 _Bieber, T; Cork, M; Ellis, C; Girolomoni, G; Groves, R; Langley, R; Luger, T; Meurer, M; Murrell, D; Orlow, S; Paller, A; de Prost, Y; Puig, L; Ring, J; Saurat, JH; Schwarz, T; Shear, N; Stingl, G; Taieb, A; Thestrup-Pedersen, K_  
2005 SEP ;211(2):77-78, Dermatology  
— id: 57807, year: 2005, vol: 211, page: 77, stat: Journal Article, 

**Pityriasis rubra pilaris, type IV**  
 _Bragg, Jennifer; Witkiewicz, Agnieszka; Orlow, Seth J; Schaffer, Julie V_  
2005 ;11(4):14-14, Dermatology online journal  
— id: 66687, year: 2005, vol: 11, page: 14, stat: Journal Article, 

**Treatment of children and adolescents with methotrexate, cyclosporine, and etanercept: review of the dermatologic and rheumatologic literature**  
 _Dadlani, Chicky; Orlow, Seth J_  
2005 Feb;52(2):316-340, Journal of the American Academy of Dermatology  
— id: 49630, year: 2005, vol: 52, page: 316, stat: Journal Article, 

**Degradation of tyrosinase induced by phenylthiourea occurs following Golgi maturation**  
 _Hall, Andrea M; Orlow, Seth J_  
2005 Apr;18(2):122-129, Pigment cell research  
— id: 49628, year: 2005, vol: 18, page: 122, stat: Journal Article, 

**X-linked recessive ichthyosis**  
 _Hazan, Carole; Orlow, Seth J; Schaffer, Julie V_  
2005 ;11(4):12-12, Dermatology online journal  
— id: 66685, year: 2005, vol: 11, page: 12, stat: Journal Article, 

**Juvenile amyopathic dermatomyositis**  
 _Henning, J Scott; Witkiewicz, Agnieszka; Schaffer, Julie V; Orlow, Seth J_  
2005 ;11(4):11-11, Dermatology online journal  
— id: 66684, year: 2005, vol: 11, page: 11, stat: Journal Article, 

**Identification of the F1F0 mitochondrial ATPase as a target for modulating skin pigmentation by screening a tagged triazine library in zebrafish**  
 _Jung, Da-Woon; Williams, Darren; Khersonsky, Sonya M; Kang, Tae-Wook; Heidary, Noushin; Chang, Young-Tae; Orlow, Seth J_  
2005 May;1(1):85-92, Molecular bioSystems  
— id: 96938, year: 2005, vol: 1, page: 85, stat: Journal Article, 

**Triazine-based tyrosinase inhibitors identified by chemical genetic screening**  
 _Ni-Komatsu, Li; Leung, Jennifer K; Williams, Darren; Min, Jaeki; Khersonsky, Sonya M; Chang, Young-Tae; Orlow, Seth J_  
2005 Dec;18(6):447-453, Pigment cell research  
— id: 61853, year: 2005, vol: 18, page: 447, stat: Journal Article, 

**Melanocytic proliferations in the setting of vulvar lichen sclerosus: diagnostic considerations**  
 _Schaffer, Julie V; Orlow, Seth J_  
2005 May-Jun;22(3):276-8; author reply 278, Pediatric dermatology  
— id: 114479, year: 2005, vol: 22, page: 276, stat: Journal Article, 

**Dissection of melanogenesis with small molecules identifies prohibitin as a regulator**  
 _Snyder, Jane R; Hall, Andrea; Ni-Komatsu, Li; Khersonsky, Sonya M; Chang, Young-Tae; Orlow, Seth J_  
2005 Apr;12(4):477-484, Chemistry & biology  
— id: 56127, year: 2005, vol: 12, page: 477, stat: Journal Article, 

**Efficacy and safety of oral retinoids in psoriasis**  
 _Van Zander, JoEllen; Orlow, Seth J_  
2005 Jan;4(1):129-138, Expert opinion on drug safety  
— id: 49629, year: 2005, vol: 4, page: 129, stat: Journal Article, 

**The Tyr (albino) locus of the laboratory mouse**  
 _Beermann, Friedrich; Orlow, Seth J; Lamoreux, M Lynn_  
2004 Oct;15(10):749-758, Mammalian genome  
— id: 49631, year: 2004, vol: 15, page: 749, stat: Journal Article, 

**Infantile granular parakeratosis: recognition of two clinical patterns**  
 _Chang, Mary Wu; Kaufmann, Julie M; Orlow, Seth J; Cohen, David E; Mobini, Narciss; Kamino, Hideko_  
2004 May;50(5 Suppl):S93-S96, Journal of the American Academy of Dermatology  
— id: 44892, year: 2004, vol: 50, page: S93, stat: Journal Article, 

**Correction of defective early tyrosinase processing by bafilomycin A1 and monensin in pink-eyed dilution melanocytes**  
 _Chen, Kun; Minwalla, Ljiljana; Ni, Li; Orlow, Seth J_  
2004 Mar;17(1):36-42, Pigment cell research  
— id: 45993, year: 2004, vol: 17, page: 36, stat: Journal Article, 

**25-Hydroxycholesterol acts in the Golgi compartment to induce degradation of tyrosinase**  
 _Hall, AM; Krishnamoorthy, L; Orlow, SJ_  
2004 MAR ;122(3):A150-A150, Journal of investigative dermatology  
— id: 46585, year: 2004, vol: 122, page: A150, stat: Journal Article, 

**25-hydroxycholesterol acts in the Golgi compartment to induce degradation of tyrosinase**  
 _Hall, Andrea M; Krishnamoorthy, Lalitha; Orlow, Seth J_  
2004 Aug;17(4):396-406, Pigment cell research  
— id: 48070, year: 2004, vol: 17, page: 396, stat: Journal Article, 

**Mucosal dominant pemphigus vulgaris with anti-desmoplakin autoantibodies**  
 _Mimouni, Daniel; Foedinger, Dagmar; Kouba, Dave J; Orlow, Seth J; Rappersberger, Klemens; Sciubba, James J; Nikolskaia, Olga V; Cohen, Bernard A; Anhalt, Grant J; Nousari, Carlos H_  
2004 Jul;51(1):62-67, Journal of the American Academy of Dermatology  
— id: 49633, year: 2004, vol: 51, page: 62, stat: Journal Article, 

**Juvenile myelomonocytic leukemia presenting with features of hemophagocytic lymphohistiocytosis in association with neurofibromatosis and juvenile xanthogranulomas**  
 _Shin, Helen T; Harris, Michael B; Orlow, Seth J_  
2004 Oct;26(9):591-595, Journal of pediatric hematology/oncology  
— id: 46088, year: 2004, vol: 26, page: 591, stat: Journal Article, 

**Infantile systemic hyalinosis**  
 _Shin, Helen T; Paller, Amy; Hoganson, George; Willner, Judith P; Chang, Mary Wu; Orlow, Seth J_  
2004 Feb;50(2 Suppl):S61-S64, Journal of the American Academy of Dermatology  
— id: 42618, year: 2004, vol: 50, page: S61, stat: Journal Article, 

**Oxidative stress activates FUS1 and RLM1 transcription in the yeast Saccharomyces cerevisiae in an oxidant-dependent Manner**  
 _Staleva, Liliana; Hall, Andrea; Orlow, Seth J_  
2004 Dec;15(12):5574-5582, Molecular biology of the cell  
— id: 49632, year: 2004, vol: 15, page: 5574, stat: Journal Article, 

**Identification of compounds that bind mitochondrial F1F0 ATPase by screening a triazine library for correction of albinism**  
 _Williams, Darren; Jung, Da-Woon; Khersonsky, Sonya M; Heidary, Noushin; Chang, Young-Tae; Orlow, Seth J_  
2004 Sep;11(9):1251-1259, Chemistry & biology  
— id: 48871, year: 2004, vol: 11, page: 1251, stat: Journal Article, 

**Oral retinoid therapy for dermatologic conditions in children and adolescents**  
 _Brecher, Alexandra R; Orlow, Seth J_  
2003 Aug;49(2):171-82; quiz 183, Journal of the American Academy of Dermatology  
— id: 39120, year: 2003, vol: 49, page: 171, stat: Journal Article, 

**Accumulation of Tyrosinase in the Endolysosomal Compartment is Induced by U18666A**  
 _Hall, Andrea M; Krishnamoorthy, Lalitha; Orlow, Seth J_  
2003 Apr;16(2):149-158, Pigment cell research  
— id: 34780, year: 2003, vol: 16, page: 149, stat: Journal Article, 

**Molecular analysis of the glomulin gene in glomuvenous malformation families**  
 _Kloos, MT; Crocker, E; Haisley-Royster, C; Hunter, CL; Leedom, TP; Nevin, NC; Orlow, SJ; Prose, N; Simpson, SA; Vance, GH; Murrell, DF; Marchuk, DA_  
2003 NOV ;73(5):571-571, American journal of human genetics  
— id: 55456, year: 2003, vol: 73, page: 571, stat: Journal Article, 

**Annual trainee award, 2001-2002**  
 _Orlow, SJ_  
2003 ;139(3):378-, Archives of dermatology  
— id: 651742, year: 2003, vol: 139, page: 378, stat: Journal Article, 

**Pink-eyed dilution protein controls the processing of tyrosinase**  
 _Chen, Kun; Manga, Prashiela; Orlow, Seth J_  
2002 Jun;13(6):1953-1964, Molecular biology of the cell  
— id: 34784, year: 2002, vol: 13, page: 1953, stat: Journal Article, 

**Rab27b association with melanosomes: dominant negative mutants disrupt melanosomal movement**  
 _Chen, Yanru; Samaraweera, Preminda; Sun, Tung-Tien; Kreibich, Gert; Orlow, Seth J_  
2002 Jun;118(6):933-940, Journal of investigative dermatology  
— id: 32487, year: 2002, vol: 118, page: 933, stat: Journal Article, 

**The pink-eyed dilution protein modulates arsenic sensitivity and intracellular glutathione metabolism**  
 _Greger, LS; Orlow, SJ_  
2002 NOV ;13(4):540A-540A, Molecular biology of the cell  
— id: 37195, year: 2002, vol: 13, page: 540A, stat: Journal Article, 

**Accumulation of tyrosinase in the endolysosomal compartment is induced by U18666A**  
 _Hall, AM; Krishnamoorthy, L; Orlow, SJ_  
2002 NOV ;13(4):540A-541A, Molecular biology of the cell  
— id: 37196, year: 2002, vol: 13, page: 540A, stat: Journal Article, 

**Pink-eyed Dilution Protein Modulates Arsenic Sensitivity and Intracellular Glutathione Metabolism**  
 _Staleva, Liliana; Manga, Prashiela; Orlow, Seth J_  
2002 Dec;13(12):4206-4220, Molecular biology of the cell  
— id: 34781, year: 2002, vol: 13, page: 4206, stat: Journal Article, 

**p16(Ink4a) in melanocyte senescence and differentiation**  
 _Sviderskaya, Elena V; Hill, Simon P; Evans-Whipp, Tracy J; Chin, Lynda; Orlow, Seth J; Easty, David J; Cheong, Sok Ching; Beach, David; DePinho, Ronald A; Bennett, Dorothy C_  
2002 Mar 20;94(6):446-454, Journal of the National Cancer Institute  
— id: 34785, year: 2002, vol: 94, page: 446, stat: Journal Article, 

**Extensive Riga-Fede disease of the lip and tongue**  
 _Zaenglein, Andrea L; Chang, Mary Wu; Meehan, Shane A; Axelrod, Felicia B; Orlow, Seth J_  
2002 Sep;47(3):445-447, Journal of the American Academy of Dermatology  
— id: 34782, year: 2002, vol: 47, page: 445, stat: Journal Article, 

**Congenital Spitz nevus clinically mimicking melanoma**  
 _Zaenglein, Andrea L; Heintz, Patrick; Kamino, Hideko; Zisblatt, Martin; Orlow, Seth J_  
2002 Sep;47(3):441-444, Journal of the American Academy of Dermatology  
— id: 34783, year: 2002, vol: 47, page: 441, stat: Journal Article, 

**Additional glomangioma families link to chromosome 1p: no evidence for genetic heterogeneity**  
 _Calvert JT; Burns S; Riney TJ; Sahoo T; Orlow SJ; Nevin NC; Haisley-Royster C; Prose N; Simpson SA; Speer MC; Marchuk DA_  
2001 ;51(3):180-182, Human heredity  
— id: 34791, year: 2001, vol: 51, page: 180, stat: Journal Article, 

**Abnormal tyrosinase processing and fate in melanocytes lacking the pink-eyed dilution gene**  
 _Chen, K; Manga, P; Orlow, S_  
2001 AUG ;117(2):510-510, Journal of investigative dermatology  
— id: 54904, year: 2001, vol: 117, page: 510, stat: Journal Article, 

**Mislocalization of melanosomal proteins in melanocytes from mice with oculocutaneous albinism type 2**  
 _Manga P; Boissy RE; Pifko-Hirst S; Zhou BK; Orlow SJ_  
2001 Jun;72(6):695-710, Experimental eye research  
— id: 21192, year: 2001, vol: 72, page: 695, stat: Journal Article, 

**Inverse correlation between pink-eyed dilution protein expression and induction of melanogenesis by bafilomycin A1**  
 _Manga P; Orlow SJ_  
2001 Oct;14(5):362-367, Pigment cell research  
— id: 34788, year: 2001, vol: 14, page: 362, stat: Journal Article, 

**Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63**  
 _McGrath JA; Duijf PH; Doetsch V; Irvine AD; de Waal R; Vanmolkot KR; Wessagowit V; Kelly A; Atherton DJ; Griffiths WA; Orlow SJ; van Haeringen A; Ausems MG; Yang A; McKeon F; Bamshad MA; Brunner HG; Hamel BC; van Bokhoven H_  
2001 Feb 1;10(3):221-229, Human molecular genetics  
— id: 34792, year: 2001, vol: 10, page: 221, stat: Journal Article, 

**Annual Trainee Award for 2000**  
 _Orlow SJ_  
2001 Jul;137(7):948-948, Archives of dermatology  
— id: 21118, year: 2001, vol: 137, page: 948, stat: Journal Article, 

**Consultations & comments: reader reaction and timely answers from experts. Pityriasis alba: how to recognize and treat**  
 _Orlow SJ_  
2001 Feb;41(2):166-166, Consultant  
— id: 26861, year: 2001, vol: 41, page: 166, stat: Journal Article, 

**Managing atopic dermatitis in children**  
 _Orlow, Seth J_  
Richmond VA : VCU Dept. of Continuing Medical Education, 2001,   
— id: 1625, year: 2001, vol: , page: , stat: , 

**Intracellular distribution and late endosomal effects of the ocular albinism 1 gene product: Consequences of disease-causing mutations and implications for melanosome biogenesis**  
 _Rosenberg, B; Shen, B; Orlow, S_  
2001 AUG ;117(2):510-510, Journal of investigative dermatology  
— id: 54905, year: 2001, vol: 117, page: 510, stat: Journal Article, 

**The mouse ocular albinism 1 gene product is an endolysosomal protein**  
 _Samaraweera P; Shen B; Newton JM; Barsh GS; Orlow SJ_  
2001 Mar;72(3):319-329, Experimental eye research  
— id: 21249, year: 2001, vol: 72, page: 319, stat: Journal Article, 

**Speckled lentiginous nevus--classic congenital melanocytic nevus hybrid not the result of "collision"**  
_Schaffer JV; Orlow SJ; Lazova R; Bolognia JL_  
2001 Dec;137(12):1655-1655, Archives of dermatology  
— id: 34787, year: 2001, vol: 137, page: 1655, stat: Journal Article, 

**Speckled lentiginous nevus: within the spectrum of congenital melanocytic nevi**  
 _Schaffer JV; Orlow SJ; Lazova R; Bolognia JL_  
2001 Feb;137(2):172-178, Archives of dermatology  
— id: 34790, year: 2001, vol: 137, page: 172, stat: Journal Article, 

**The ocular albinism type 1 gene product is an N-glycoprotein but glycosylation is not required for its subcellular distribution**  
 _Shen B; Orlow SJ_  
2001 Dec;14(6):485-490, Pigment cell research  
— id: 34786, year: 2001, vol: 14, page: 485, stat: Journal Article, 

**Intracellular distribution and late endosomal effects of the ocular albinism type 1 gene product: consequences of disease-causing mutations and implications for melanosome biogenesis**  
 _Shen B; Rosenberg B; Orlow SJ_  
2001 Mar;2(3):202-211, Traffic  
— id: 21229, year: 2001, vol: 2, page: 202, stat: Journal Article, 

**Ocular albinism type 1: more than meets the eye**  
 _Shen B; Samaraweera P; Rosenberg B; Orlow SJ_  
2001 Aug;14(4):243-248, Pigment cell research  
— id: 34789, year: 2001, vol: 14, page: 243, stat: Journal Article, 

**Diaper dermatitis**  
 _Tarsis SL; Orlow SJ_  
Current dermatologic diagnosis & treatment Philadelphia : Lippincott Williams & Wilkins, 2001,   
— id: 3694, year: 2001, vol: , page: 48, stat: Chapter, 

**Congenital granular cell tumors localized to the arm**  
 _Zaenglein AL; Meehan SA; Orlow SJ_  
2001 May-Jun;18(3):234-237, Pediatric dermatology  
— id: 21152, year: 2001, vol: 18, page: 234, stat: Journal Article, 

**Mutational analysis of the modulation of tyrosinase by tyrosinase-related proteins 1 and 2 in vitro**  
 _Manga P; Sato K; Ye L; Beermann F; Lamoreux ML; Orlow SJ_  
2000 Oct;13(5):364-374, Pigment cell research  
— id: 34794, year: 2000, vol: 13, page: 364, stat: Journal Article, 

**A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-gamma (NEMO)**  
_Zonana J; Elder ME; Schneider LC; Orlow SJ; Moss C; Golabi M; Shapira SK; Farndon PA; Wara DW; Emmal SA; Ferguson BM_  
2000 Dec;67(6):1555-1562, American journal of human genetics  
— id: 34793, year: 2000, vol: 67, page: 1555, stat: Journal Article, 

**Atypical erythema toxicum neonatorum of delayed onset in a term infant**  
 _Chang MW; Jiang SB; Orlow SJ_  
1999 Mar-Apr;16(2):137-141, Pediatric dermatology  
— id: 12012, year: 1999, vol: 16, page: 137, stat: Journal Article, 

**Erythema induratum of Bazin in an infant**  
 _Chang MW; Lawrence R; Orlow SJ_  
1999 Feb;103(2):498-499, Pediatrics  
— id: 7311, year: 1999, vol: 103, page: 498, stat: Journal Article, 

**Neonatal erosions and ulcerations in giant congenital melanocytic nevi**  
 _Giam YC; Williams ML; Leboit PE; Orlow SJ; Eichenfield LF; Frieden IJ_  
1999 Sep-Oct;16(5):354-358, Pediatric dermatology  
— id: 34795, year: 1999, vol: 16, page: 354, stat: Journal Article, 

**Unusual distribution of acanthosis nigricans in the Crouzonodermoskeletal syndrome**  
 _Goodrich, JT; Orlow, S; Staffenberg, D; Marion, R; Eisig, S; Shanske, A_  
1999 OCT ;65(4):A150-A150, American journal of human genetics  
— id: 53824, year: 1999, vol: 65, page: A150, stat: Journal Article, 

**The pink-eyed dilution gene and the molecular pathogenesis of tyrosinase-positive albinism (OCA2)**  
_Manga P; Orlow SJ_  
1999 Nov;26(11):738-747, Journal of dermatology  
— id: 11863, year: 1999, vol: 26, page: 738, stat: Journal Article, 

**The pink-eyed dilution locus controls the biogenesis of melanosomes and levels of melanosomal proteins in the eye**  
 _Orlow SJ; Brilliant MH_  
1999 Feb;68(2):147-154, Experimental eye research  
— id: 56407, year: 1999, vol: 68, page: 147, stat: Journal Article, 

**Pediatric and adolescent dermatology - Introduction**  
 _Orlow, SJ_  
1999 SEP ;18(3):185-186, Seminars in cutaneous medicine & surgery  
— id: 53969, year: 1999, vol: 18, page: 185, stat: Journal Article, 

**Seminars in Cutaneous Medicine and Surgery: Introduction**  
 _Orlow, SJ_  
1999 ;18(3):185-186, Seminars in cutaneous medicine & surgery  
— id: 637762, year: 1999, vol: 18, page: 185, stat: Journal Article, 

**Hypohidrotic ectodermal dysplasia and Hypomelanosis of Ito in a girl with a de novo t(X;13)(g13;p11.2)**  
_Orlow, SJ; Marion, R; Duncan, C; Gu, H; Genovese, M; Jenkins, E; Shanske, A_  
1999 OCT ;65(4):A353-A353, American journal of human genetics  
— id: 53832, year: 1999, vol: 65, page: A353, stat: Journal Article, 

**Altered N-glycosylation in macrophage x melanoma fusion hybrids**  
 _Pawelek JM; Chakraborty AK; Rachkovsky ML; Orlow SJ; Bolognia JL; Sodi SA_  
1999 Nov;45(7):1011-1027, Cellular & molecular biology  
— id: 57567, year: 1999, vol: 45, page: 1011, stat: Journal Article, 

**Identification and characterization of a melanocyte-specific novel 65-kDa peripheral membrane protein**  
 _Samaraweera P; Donatien PD; Qazi S; Kobayashi T; Hearing VJ; Panthier JJ; Orlow SJ_  
1999 Dec;266(3):924-934, European journal of biochemistry  
— id: 8593, year: 1999, vol: 266, page: 924, stat: Journal Article, 

**Genetic mapping of a novel familial form of infantile hemangioma**  
 _Walter JW; Blei F; Anderson JL; Orlow SJ; Speer MC; Marchuk DA_  
1999 Jan 1;82(1):77-83, American journal of medical genetics  
— id: 57079, year: 1999, vol: 82, page: 77, stat: Journal Article, 

**Familial segregation of hemangiomas and vascular malformations as an autosomal dominant trait [see comments] [published erratum appears in Arch Dermatol 1998 Nov;134(11):1425]**  
_Blei F; Walter J; Orlow SJ; Marchuk DA_  
1998 Jun;134(6):718-722, Archives of dermatology  
— id: 7506, year: 1998, vol: 134, page: 718, stat: Journal Article, 

**Molluscum contagiosum in children: When - And how - To treat**  
 _Chang MW; Orlow SJ_  
1998 ;38(6):1593-1599, Consultant  
— id: 15955, year: 1998, vol: 38, page: 1593, stat: Journal Article, 

**Comparative decreases in tyrosinase, TRP-1, TRP-2, and Pmel 17/silver antigenic proteins from melanotic to amelanotic stages of syngeneic mouse cutaneous melanomas and metastases**  
 _Orlow SJ; Silvers WK; Zhou BK; Mintz B_  
1998 Apr 1;58(7):1521-1523, Cancer research  
— id: 12140, year: 1998, vol: 58, page: 1521, stat: Journal Article, 

**Melanosomal defects in melanocytes from mice lacking expression of the pink-eyed dilution gene: correction by culture in the presence of excess tyrosine**  
 _Rosemblat S; Sviderskaya EV; Easty DJ; Wilson A; Kwon BS; Bennett DC; Orlow SJ_  
1998 Mar 15;239(2):344-352, Experimental cell research  
— id: 34799, year: 1998, vol: 239, page: 344, stat: Journal Article, 

**OA1 mutations and deletions in X-linked ocular albinism**  
 _Schnur RE; Gao M; Wick PA; Keller M; Benke PJ; Edwards MJ; Grix AW; Hockey A; Jung JH; Kidd KK; Kistenmacher M; Levin AV; Lewis RA; Musarella MA; Nowakowski RW; Orlow SJ; Pagon RS; Pillers DA; Punnett HH; Quinn GE; Tezcan K; Wagstaff J; Weleber RG_  
1998 Apr;62(4):800-809, American journal of human genetics  
— id: 34798, year: 1998, vol: 62, page: 800, stat: Journal Article, 

**Expression of tyrosinase and the tyrosinase related proteins in the Mitfvit (vitiligo) mouse eye: implications for the function of the microphthalmia transcription factor**  
 _Smith SB; Zhou BK; Orlow SJ_  
1998 Apr;66(4):403-410, Experimental eye research  
— id: 34797, year: 1998, vol: 66, page: 403, stat: Journal Article, 

**Melanoma x macrophage fusion hybrids acquire increased melanogenesis and metastatic potential: altered N-glycosylation as an underlying mechanism**  
 _Sodi SA; Chakraborty AK; Platt JT; Kolesnikova N; Rosemblat S; Keh-Yen A; Bolognia JL; Rachkovsky ML; Orlow SJ; Pawelek JM_  
1998 Oct;11(5):299-309, Pigment cell research  
— id: 34796, year: 1998, vol: 11, page: 299, stat: Journal Article, 

**Multimodal management of diffuse neonatal hemangiomatosis**  
 _Blei F; Orlow SJ; Geronemus R_  
1997 Dec;37(6):1019-1021, Journal of the American Academy of Dermatology  
— id: 57104, year: 1997, vol: 37, page: 1019, stat: Journal Article, 

**A study of large congenital melanocytic nevi and associated malignant melanomas: review of cases in the New York University Registry and the world literature**  
 _DeDavid M; Orlow SJ; Provost N; Marghoob AA; Rao BK; Huang CL; Wasti Q; Kopf AW; Bart RS_  
1997 Mar;36(3 Pt 1):409-416, Journal of the American Academy of Dermatology  
— id: 12367, year: 1997, vol: 36, page: 409, stat: Journal Article, 

**Regulation of melanogenesis by human uveal melanocytes in vitro**  
 _Hu DN; McCormick SA; Orlow SJ; Rosemblat S; Lin AY_  
1997 Mar;64(3):397-404, Experimental eye research  
— id: 34800, year: 1997, vol: 64, page: 397, stat: Journal Article, 

**Albinism: an update**  
 _Orlow SJ_  
1997 Mar;16(1):24-29, Seminars in cutaneous medicine & surgery  
— id: 7232, year: 1997, vol: 16, page: 24, stat: Journal Article, 

**Congenital melanocytic nevi**  
 _Orlow SJ_  
Grabb and Smith's plastic surgery Philadelphia : Lippicott-Raven, 1997,   
— id: 3521, year: 1997, vol: , page: ?, stat: Chapter, 

**Increased risk of symptomatic hemangiomas of the airway in association with cutaneous hemangiomas in a "beard" distribution [see comments]**  
_Orlow SJ; Isakoff MS; Blei F_  
1997 Oct;131(4):643-646, Journal of pediatrics  
— id: 12218, year: 1997, vol: 131, page: 643, stat: Journal Article, 

**Evaluation of tyrosinase and tyrosinase related proteins in the RPE/choroid of vitiligo (mi(vit)/mi(vit)) mice**  
 _Smith, SB; Zhou, BK; Orlow, SJ_  
1997 MAR 15 ;38(4):1514-1514, Investigative ophthalmology & visual science. IOVS  
— id: 53233, year: 1997, vol: 38, page: 1514, stat: Journal Article, 

**Novel mutations of the tyrosinase (TYR) gene in type I oculocutaneous albinism (OCA1)**  
_Spritz RA; Oh J; Fukai K; Holmes SA; Ho L; Chitayat D; France TD; Musarella MA; Orlow SJ; Schnur RE; Weleber RG; Levin AV_  
1997 ;10(2):171-174, Human mutation  
— id: 34801, year: 1997, vol: 10, page: 171, stat: Journal Article, 

**Neurocutaneous melanosis: clinical features of large congenital melanocytic nevi in patients with manifest central nervous system melanosis**  
 _DeDavid M; Orlow SJ; Provost N; Marghoob AA; Rao BK; Wasti Q; Huang CL; Kopf AW; Bart RS_  
1996 Oct;35(4):529-538, Journal of the American Academy of Dermatology  
— id: 12534, year: 1996, vol: 35, page: 529, stat: Journal Article, 

**Melanosomal and lysosomal alterations in murine melanocytes following transfection with the v-rasHa oncogene**  
 _Donatien PD; Diment SL; Boissy RE; Orlow SJ_  
1996 May 16;66(4):557-563, International journal of cancer  
— id: 12603, year: 1996, vol: 66, page: 557, stat: Journal Article, 

**Melanosomal and lysosomal alterations in murine melanocytes following transfection with the v-ras(Ha) oncogene**  
 _Donatien, PD; Diment, SL; Boissy, RE; Orlow, SJ_  
1996 APR ;106(4):120-120, Journal of investigative dermatology  
— id: 52996, year: 1996, vol: 106, page: 120, stat: Journal Article, 

**Clinicopathologic findings in the Bannayan-Riley-Ruvalcaba syndrome**  
 _Fargnoli MC; Orlow SJ; Semel-Concepcion J; Bolognia JL_  
1996 Oct;132(10):1214-1218, Archives of dermatology  
— id: 34802, year: 1996, vol: 132, page: 1214, stat: Journal Article, 

**CHILD syndrome in a boy**  
 _Happle R; Effendy I; Megahed M; Orlow SJ; Kuster W_  
1996 Mar 15;62(2):192-194, American journal of medical genetics  
— id: 34803, year: 1996, vol: 62, page: 192, stat: Journal Article, 

**Cutaneous findings in mosaicism and chimerism**  
 _Loomis CA; Orlow SJ_  
1996 ;3:87-92, Current opinion in dermatology  
— id: 48978, year: 1996, vol: 3, page: 87, stat: Journal Article, 

**Large congenital melanocytic nevi and the risk for the development of malignant melanoma. A prospective study**  
 _Marghoob AA; Schoenbach SP; Kopf AW; Orlow SJ; Nossa R; Bart RS_  
1996 Feb;132(2):170-175, Archives of dermatology  
— id: 6933, year: 1996, vol: 132, page: 170, stat: Journal Article, 

**Analysis of 54 cases of hypopigmentation and hyperpigmentation along the lines of Blaschko [see comments]**  
_Nehal KS; PeBenito R; Orlow SJ_  
1996 Oct;132(10):1167-1170, Archives of dermatology  
— id: 12535, year: 1996, vol: 132, page: 1167, stat: Journal Article, 

**Isolation and characterization of a mouse homolog of the X-linked ocular albinism (OA1) gene**  
 _Newton JM; Orlow SJ; Barsh GS_  
1996 Oct 15;37(2):219-225, Genomics  
— id: 57487, year: 1996, vol: 37, page: 219, stat: Journal Article, 

**Aging of the murine melanocyte system in normal and phatologic states**  
 _Orlow SJ_  
Pathobiology of the aging mouse Washington DC : ILSI Press, 1996,   
— id: 3519, year: 1996, vol: , page: ?, stat: Chapter, 

**Co-expression of differentiated functions in highly metastatic melanoma macrophage fusion hybrids**  
 _Pawelek, JM; Sodi, SA; Chakraborty, AK; Avissar, YJ; Orlow, SJ; Rachkovsky, ML; Rosemblat, S; KehYen, A; Bermudes, DG; Bolognia, J_  
1996 APR ;106(4):298-298, Journal of investigative dermatology  
— id: 53001, year: 1996, vol: 106, page: 298, stat: Journal Article, 

**Fibroblast growth factor receptor 2 mutations in Beare-Stevenson cutis gyrata syndrome**  
 _Przylepa, KA; Paznekas, W; Zhang, MH; Golabi, M; Bias, W; Bamshad, MJ; Carey, JC; Hall, BD; Stevenson, R; Orlow, SJ; Cohen, MM; Jabs, EW_  
1996 AUG ;13(4):492-494, Nature genetics  
— id: 52841, year: 1996, vol: 13, page: 492, stat: Journal Article, 

**Misrouting of tyrosinase with a truncated cytoplasmic tail as a result of the murine platinum (cp) mutation**  
 _Beermann F; Orlow SJ; Boissy RE; Schmidt A; Boissy YL; Lamoreux ML_  
1995 Nov;61(5):599-607, Experimental eye research  
— id: 56743, year: 1995, vol: 61, page: 599, stat: Journal Article, 

**Lysosomal hydrolases are present in melanosomes and are elevated in melanizing cells**  
 _Diment S; Eidelman M; Rodriguez GM; Orlow SJ_  
1995 Mar 3;270(9):4213-4215, Journal of biological chemistry  
— id: 6605, year: 1995, vol: 270, page: 4213, stat: Journal Article, 

**Interaction of melanosomal proteins with melanin**  
 _Donatien PD; Orlow SJ_  
1995 Aug 15;232(1):159-164, European journal of biochemistry  
— id: 6821, year: 1995, vol: 232, page: 159, stat: Journal Article, 

**Melanogenesis by human uveal melanocytes in vitro**  
 _Hu DN; McCormick SA; Orlow SJ; Rosemblat S; Lin AY; Wo K_  
1995 Apr;36(5):931-938, Investigative ophthalmology & visual science. IOVS  
— id: 34807, year: 1995, vol: 36, page: 931, stat: Journal Article, 

**REGULATION OF MELANOGENESIS BY HUMAN UVEAL MELANOCYTES IN-VITRO**  
 _HU, DN; MCCORMICK, SA; LIN, AY; ORLOW, SJ; ROSEMBLAT, S; PAKA, K; BABU, A; PENCHASZADEH, VB_  
1995 MAR 15 ;36(4):S553-S553, Investigative ophthalmology & visual science. IOVS  
— id: 87338, year: 1995, vol: 36, page: S553, stat: Journal Article, 

**The pinkeyed-dilution protein and the eumelanin/pheomelanin switch: in support of a unifying hypothesis**  
 _Lamoreux ML; Zhou BK; Rosemblat S; Orlow SJ_  
1995 Oct;8(5):263-270, Pigment cell research  
— id: 34805, year: 1995, vol: 8, page: 263, stat: Journal Article, 

**LARGE CONGENITAL MELANOCYTIC NEVI AND THE RISK OF DEVELOPING MALIGNANT-MELANOMA - A PROSPECTIVE-STUDY AND REVIEW OF THE WORLDS LITERATURE**  
 _MARGHOOB, AA; SCHOENBACH, SP; KOPF, AW; ORLOW, SJ; MOSSA, R; BART, RS_  
1995 APR ;104(4):563-563, Journal of investigative dermatology  
— id: 87376, year: 1995, vol: 104, page: 563, stat: Journal Article, 

**Fibroblast growth factor receptor 3 (FGFR3) transmembrane mutation in Crouzon syndrome with acanthosis nigricans**  
 _Meyers GA; Orlow SJ; Munro IR; Przylepa KA; Jabs EW_  
1995 Dec;11(4):462-464, Nature genetics  
— id: 34804, year: 1995, vol: 11, page: 462, stat: Journal Article, 

**Congenital disorders of hypopigmentation**  
 _Orlow SJ_  
1995 Mar;14(1):27-32, Seminars in dermatology  
— id: 6707, year: 1995, vol: 14, page: 27, stat: Journal Article, 

**Melanomas in children**  
 _Orlow SJ_  
1995 Oct;16(10):365-369, Pediatrics in review  
— id: 7231, year: 1995, vol: 16, page: 365, stat: Journal Article, 

**Melanosomes are specialized members of the lysosomal lineage of organelles**  
 _Orlow SJ_  
1995 Jul;105(1):3-7, Journal of investigative dermatology  
— id: 6854, year: 1995, vol: 105, page: 3, stat: Journal Article, 

**Changes in expression of putative antigens encoded by pigment genes in mouse melanomas at different stages of malignant progression**  
 _Orlow SJ; Hearing VJ; Sakai C; Urabe K; Zhou BK; Silvers WK; Mintz B_  
1995 Oct 24;92(22):10152-10156, Proceedings of the National Academy of Sciences of the United States of America  
— id: 12719, year: 1995, vol: 92, page: 10152, stat: Journal Article, 

**Novel FGFR2 mutations in Crouzon and Jackson-Weiss syndromes show allelic heterogeneity and phenotypic variability**  
 _Park WJ; Meyers GA; Li X; Theda C; Day D; Orlow SJ; Jones MC; Jabs EW_  
1995 Jul;4(7):1229-1233, Human molecular genetics  
— id: 34806, year: 1995, vol: 4, page: 1229, stat: Journal Article, 

**Lines of Blaschko**  
 _Bolognia JL; Orlow SJ; Glick SA_  
1994 Aug;31(2 Pt 1):157-90; quiz 190, Journal of the American Academy of Dermatology  
— id: 34809, year: 1994, vol: 31, page: 157, stat: Journal Article, 

**The Pmel 17/silver locus protein. Characterization and investigation of its melanogenic function**  
 _Kobayashi T; Urabe K; Orlow SJ; Higashi K; Imokawa G; Kwon BS; Potterf B; Hearing VJ_  
1994 Nov 18;269(46):29198-29205, Journal of biological chemistry  
— id: 34808, year: 1994, vol: 269, page: 29198, stat: Journal Article, 

**MELANOGENESIS IN CULTURED HUMAN UVEAL MELANOCYTES**  
 _LIN, AY; HU, DN; ORLOW, SJ; WO, K; MCCORMICK, SA_  
1994 MAR 15 ;35(4):1927-1927, Investigative ophthalmology & visual science. IOVS  
— id: 52559, year: 1994, vol: 35, page: 1927, stat: Journal Article, 

**High-molecular-weight forms of tyrosinase and the tyrosinase-related proteins: evidence for a melanogenic complex**  
 _Orlow SJ; Zhou BK; Chakraborty AK; Drucker M; Pifko-Hirst S; Pawelek JM_  
1994 Aug;103(2):196-201, Journal of investigative dermatology  
— id: 12928, year: 1994, vol: 103, page: 196, stat: Journal Article, 

**Congenital and genetic disorders associated with hypopigmentation**  
 _Orlow, Seth J_  
Chicago IL : Mosby, 1994,   
— id: 1626, year: 1994, vol: , page: , stat: , 

**MULTIMERIC FORMS OF TYROSINASE AND THE TYROSINASE-RELATED PROTEINS - EVIDENCE FOR A MELANOGENIC COMPLEX**  
 _ORLOW, SJ; ZHOU, BK; CHAKRABORTY, AK; PIFKOHIRST, S; PAWELEK, JM_  
1994 APR ;102(4):552-552, Journal of investigative dermatology  
— id: 52338, year: 1994, vol: 102, page: 552, stat: Journal Article, 

**Identification of a melanosomal membrane protein encoded by the pink-eyed dilution (type II oculocutaneous albinism) gene**  
 _Rosemblat S; Durham-Pierre D; Gardner JM; Nakatsu Y; Brilliant MH; Orlow SJ_  
1994 Dec 6;91(25):12071-12075, Proceedings of the National Academy of Sciences of the United States of America  
— id: 56701, year: 1994, vol: 91, page: 12071, stat: Journal Article, 

**Identification of a melanosomal matrix protein encoded by the murine si (silver) locus using "organelle scanning"**  
_Zhou BK; Kobayashi T; Donatien PD; Bennett DC; Hearing VJ; Orlow SJ_  
1994 Jul 19;91(15):7076-7080, Proceedings of the National Academy of Sciences of the United States of America  
— id: 12946, year: 1994, vol: 91, page: 7076, stat: Journal Article, 

**Interferon alfa-2a therapy for extensive perianal and lower extremity hemangioma**  
 _Blei F; Orlow SJ; Geronemus RG_  
1993 Jul;29(1):98-99, Journal of the American Academy of Dermatology  
— id: 8235, year: 1993, vol: 29, page: 98, stat: Journal Article, 

**Supraumbilical midabdominal raphe, sternal atresia, and hemangioma in an infant: response of hemangioma to laser and interferon alfa-2a [see comments]**  
_Blei F; Orlow SJ; Geronemus RG_  
1993 Mar;10(1):71-76, Pediatric dermatology  
— id: 9178, year: 1993, vol: 10, page: 71, stat: Journal Article, 

**Pediatric dermatology and dermatopathology : a text and atlas**  
 _Caputo, Ruggero; Ackerman, A. Bernard; Sison-Torre, Evita Q; Orlow, Seth_  
Philadelphia : Lea & Febiger, 1993,   
— id: 1623, year: 1993, vol: , page: , stat: , 

**Postnatal ocular expression of tyrosinase and related proteins: disruption by the pink-eyed unstable (p(un)) mutation**  
 _Chiu E; Lamoreux ML; Orlow SJ_  
1993 Sep;57(3):301-305, Experimental eye research  
— id: 57303, year: 1993, vol: 57, page: 301, stat: Journal Article, 

**Varicella-zoster virus infection in Romanian children infected with the human immunodeficiency virus**  
 _Leibovitz E; Cooper D; Giurgiutiu D; Coman G; Straus I; Orlow SJ; Lawrence R_  
1993 Dec;92(6):838-842, Pediatrics  
— id: 13052, year: 1993, vol: 92, page: 838, stat: Journal Article, 

**HIV infection in Romanian children: a call for antiretroviral therapy**  
 _Leibovitz E; Cooper D; Orlow SJ; Lawrence RM; Petrea S; Jipa G; Carausu S; Coman G_  
1993 Oct;6(10):1173-1173, Journal of acquired immune deficiency syndrome  
— id: 34810, year: 1993, vol: 6, page: 1173, stat: Journal Article, 

**Syndromes associated with melanocytic nevi**  
 _Marghoob AA; Orlow SJ; Kopf AW_  
1993 Sep;29(3):373-88; quiz 388, Journal of the American Academy of Dermatology  
— id: 6446, year: 1993, vol: 29, page: 373, stat: Journal Article, 

**Subcellular distribution of tyrosinase and tyrosinase-related protein-1: implications for melanosomal biogenesis**  
 _Orlow SJ; Boissy RE; Moran DJ; Pifko-Hirst S_  
1993 Jan;100(1):55-64, Journal of investigative dermatology  
— id: 13299, year: 1993, vol: 100, page: 55, stat: Journal Article, 

**AIDS-associated Kaposi's sarcoma in Romanian children**  
 _Orlow SJ; Cooper D; Petrea S; Kamino H; Popescu V; Lawrence R; Leibovitz E_  
1993 Mar;28(3):449-453, Journal of the American Academy of Dermatology  
— id: 13233, year: 1993, vol: 28, page: 449, stat: Journal Article, 

**Pathogenesis of the platinum (cp) mutation, a model for oculocutaneous albinism**  
 _Orlow SJ; Lamoreux ML; Pifko-Hirst S; Zhou BK_  
1993 Aug;101(2):137-140, Journal of investigative dermatology  
— id: 6476, year: 1993, vol: 101, page: 137, stat: Journal Article, 

**Cimetidine therapy for multiple viral warts in children**  
 _Orlow SJ; Paller A_  
1993 May;28(5 Pt 1):794-796, Journal of the American Academy of Dermatology  
— id: 6477, year: 1993, vol: 28, page: 794, stat: Journal Article, 

**Identification of a mammalian melanosomal matrix glycoprotein**  
 _Orlow SJ; Zhou BK; Boissy RE; Pifko-Hirst S_  
1993 Aug;101(2):141-144, Journal of investigative dermatology  
— id: 6475, year: 1993, vol: 101, page: 141, stat: Journal Article, 

**IDENTIFICATION OF A MAMMALIAN MELANOSOMAL MATRIX GLYCOPROTEIN**  
 _ORLOW, SJ; ZHOU, BK; BOISSY, RE_  
1993 APR ;41(2):A491-A491, Clinical research  
— id: 54302, year: 1993, vol: 41, page: A491, stat: Journal Article, 

**IDENTIFICATION OF A MAMMALIAN MELANOSOMAL MATRIX GLYCOPROTEIN**  
 _ORLOW, SJ; ZHOU, BK; BOISSY, RE_  
1993 APR ;100(4):507-507, Journal of investigative dermatology  
— id: 54242, year: 1993, vol: 100, page: 507, stat: Journal Article, 

**Lysosome-associated membrane protein-1 (LAMP-1) is the melanocyte vesicular membrane glycoprotein band II**  
 _Zhou BK; Boissy RE; Pifko-Hirst S; Moran DJ; Orlow SJ_  
1993 Feb;100(2):110-114, Journal of investigative dermatology  
— id: 13269, year: 1993, vol: 100, page: 110, stat: Journal Article, 

**Evidence that dopachrome tautomerase is a ferrous iron-binding glycoprotein**  
 _Chakraborty AK; Orlow SJ; Pawelek JM_  
1992 May 11;302(2):126-128, FEBS letters  
— id: 34812, year: 1992, vol: 302, page: 126, stat: Journal Article, 

**Induction of B16 melanoma melanogenesis by a serum-free synthetic medium**  
 _Johnston D; Orlow SJ; Levy E; Bystryn JC_  
1992 Jul;201(1):91-98, Experimental cell research  
— id: 13530, year: 1992, vol: 201, page: 91, stat: Journal Article, 

**Multiple pilomatricomas: report of two cases and review of the association with myotonic dystrophy**  
 _Kopeloff I; Orlow SJ; Sanchez MR_  
1992 Oct;50(4):290-292, Cutis  
— id: 13405, year: 1992, vol: 50, page: 290, stat: Journal Article, 

**Cutaneous findings in craniofacial malformation syndromes**  
 _Orlow SJ_  
1992 Oct;128(10):1379-1386, Archives of dermatology  
— id: 13408, year: 1992, vol: 128, page: 1379, stat: Journal Article, 

**Membrane glycoproteins common to vesicles and melanosomes in mouse melanoma cells**  
 _Orlow SJ; Chakraborty AK; Pawelek JM_  
1992 ;Suppl 2:162-170, Pigment cell research  
— id: 13783, year: 1992, vol: Suppl 2, page: 162, stat: Journal Article, 

**Cutaneous ulcerations secondary to interferon alfa therapy of Kaposi's sarcoma**  
 _Orlow SJ; Friedman-Kien AE_  
1992 Apr;128(4):566-566, Archives of dermatology  
— id: 14753, year: 1992, vol: 128, page: 566, stat: Journal Article, 

**Multiple subcutaneous leiomyosarcomas in an adolescent with AIDS**  
 _Orlow SJ; Kamino H; Lawrence RL_  
1992 Aug;14(3):265-268, American journal of pediatric hematology-oncology  
— id: 13489, year: 1992, vol: 14, page: 265, stat: Journal Article, 

**Synthesis and characterization of melanins from dihydroxyindole-2-carboxylic acid and dihydroxyindole**  
 _Orlow SJ; Osber MP; Pawelek JM_  
1992 Sep;5(3):113-121, Pigment cell research  
— id: 13461, year: 1992, vol: 5, page: 113, stat: Journal Article, 

**BIOGENESIS OF MELANOSOMES - MOLECULAR EVIDENCE FOR A MELANOSOMAL-LYSOSOMAL RELATIONSHIP**  
 _ORLOW, SJ; MORAN, D; BOISSY, RE_  
1992 APR ;40(2):A529-A529, Clinical research  
— id: 52019, year: 1992, vol: 40, page: A529, stat: Journal Article, 

**BIOGENESIS OF MELANOSOMES - MOLECULAR EVIDENCE FOR A MELANOSOMAL-LYSOSOMAL RELATIONSHIP**  
 _ORLOW, SJ; MORAN, D; BOISSY, RE_  
1992 APR ;98(4):566-566, Journal of investigative dermatology  
— id: 52028, year: 1992, vol: 98, page: 566, stat: Journal Article, 

**Molecular cascades in UV-induced melanogenesis: a central role for melanotropins?**  
_Pawelek JM; Chakraborty AK; Osber MP; Orlow SJ; Min KK; Rosenzweig KE; Bolognia JL_  
1992 Nov;5(5 Pt 2):348-356, Pigment cell research  
— id: 34811, year: 1992, vol: 5, page: 348, stat: Journal Article, 

**Fatal disseminated infection with human herpesvirus-6**  
 _Prezioso PJ; Cangiarella J; Lee M; Nuovo GJ; Borkowsky W; Orlow SJ; Greco MA_  
1992 Jun;120(6):921-923, Journal of pediatrics  
— id: 13591, year: 1992, vol: 120, page: 921, stat: Journal Article, 

**Interactions between ultraviolet light and interleukin-1 on MSH binding in both mouse melanoma and human squamous carcinoma cells**  
 _Birchall N; Orlow SJ; Kupper T; Pawelek J_  
1991 Mar 29;175(3):839-845, Biochemical & biophysical research communications  
— id: 34814, year: 1991, vol: 175, page: 839, stat: Journal Article, 

**Structural/functional relationships between internal and external MSH receptors: modulation of expression in Cloudman melanoma cells by UVB radiation**  
 _Chakraborty AK; Orlow SJ; Bolognia JL; Pawelek JM_  
1991 Apr;147(1):1-6, Journal of cellular physiology  
— id: 34813, year: 1991, vol: 147, page: 1, stat: Journal Article, 

**Skin and bones. I**  
 _Orlow SJ; Watsky KL; Bolognia JL_  
1991 Aug;25(2 Pt 1):205-221, Journal of the American Academy of Dermatology  
— id: 13947, year: 1991, vol: 25, page: 205, stat: Journal Article, 

**Skin and bones. II**  
 _Orlow SJ; Watsky KL; Bolognia JL_  
1991 Sep;25(3):447-462, Journal of the American Academy of Dermatology  
— id: 13911, year: 1991, vol: 25, page: 447, stat: Journal Article, 

**VESICULAR MEMBRANE-GLYCOPROTEINS AND MELANOSOMAL BIOGENESIS**  
 _ORLOW, SJ; CHAKRABORTY, AK; RENFRO, L; PAWELEK, JM_  
1991 APR ;39(2):A554-A554, Clinical research  
— id: 51630, year: 1991, vol: 39, page: A554, stat: Journal Article, 

**VESICULAR MEMBRANE-GLYCOPROTEINS AND MELANOSOMAL BIOGENESIS**  
 _ORLOW, SJ; CHAKRABORTY, AK; RENFRO, L; PAWELEK, JM_  
1991 APR ;96(4):630-630, Journal of investigative dermatology  
— id: 51647, year: 1991, vol: 96, page: 630, stat: Journal Article, 

**Stimulation of the receptor for melanocyte-stimulating hormone by retinoic acid**  
 _Chakraborty AK; Orlow SJ; Pawelek JM_  
1990 Dec 10;276(1-2):205-208, FEBS letters  
— id: 34815, year: 1990, vol: 276, page: 205, stat: Journal Article, 

**Inhibition of induced melanogenesis in Cloudman melanoma cells by four phenotypic modifiers**  
 _Orlow SJ; Chakraborty AK; Boissy RE; Pawelek JM_  
1990 Dec;191(2):209-218, Experimental cell research  
— id: 34816, year: 1990, vol: 191, page: 209, stat: Journal Article, 

**Retinoic acid is a potent inhibitor of inducible pigmentation in murine and hamster melanoma cell lines**  
 _Orlow SJ; Chakraborty AK; Pawelek JM_  
1990 Apr;94(4):461-464, Journal of investigative dermatology  
— id: 34818, year: 1990, vol: 94, page: 461, stat: Journal Article, 

**Internal binding sites for MSH: analyses in wild-type and variant Cloudman melanoma cells**  
 _Orlow SJ; Hotchkiss S; Pawelek JM_  
1990 Jan;142(1):129-136, Journal of cellular physiology  
— id: 34819, year: 1990, vol: 142, page: 129, stat: Journal Article, 

**Figurate and bullous eruption in association with breast carcinoma**  
 _Watsky KL; Orlow SJ; Bolognia JL_  
1990 May;126(5):649-652, Archives of dermatology  
— id: 34817, year: 1990, vol: 126, page: 649, stat: Journal Article, 

**Immunoassay and immunopurification of macrophage calmodulin-binding protein**  
 _Orlow SJ; Rosen OM_  
1987 ;139(1):148-156, Methods in enzymology  
— id: 34820, year: 1987, vol: 139, page: 148, stat: Journal Article, 

**Purification and distribution of a novel macrophage-specific calmodulin-binding glycoprotein**  
 _Orlow SJ; Rosenstreich DL; Pifko-Hirst S; Rosen OM_  
1985 Jan;134(1):449-456, Journal of immunology  
— id: 34821, year: 1985, vol: 134, page: 449, stat: Journal Article, 

**Characterization of a calmodulin-binding protein that is deficient in trifluoperazine-resistant variants of the macrophage-like cell line J774**  
 _Speaker MG; Orlow SJ; Sturgill TW; Rosen OM_  
1983 Jan;80(2):329-333, Proceedings of the National Academy of Sciences of the United States of America  
— id: 34822, year: 1983, vol: 80, page: 329, stat: Journal Article, 

**The extracellular cyclic nucleotide phosphodiesterase of Dictyostelium discoideum. Purification and characterization **  
_Orlow SJ; Shapiro RI; Franke J; Kessin RH_  
1981 Jul 25;256(14):7620-7627, Journal of biological chemistry  
— id: 34823, year: 1981, vol: 256, page: 7620, stat: Journal Article, 

**The effects of trifluoperazine on the macrophage-like cell line, J774**  
 _Speaker MG; Sturgill TW; Orlow SJ; Chia GH; Pifko-Hirst S; Rosen OM_  
1980 ;356(14):162-178, Annals of the New York Academy of Sciences  
— id: 34824, year: 1980, vol: 356, page: 162, stat: Journal Article, 

**Binding of inhibitor alters kinetic and physical properties of extracellular cyclic AMP phosphodiesterase from Dictyostelium discoideum**  
 _Kessin RH; Orlow SJ; Shapiro RI; Franke J_  
1979 Nov;76(11):5450-5454, Proceedings of the National Academy of Sciences of the United States of America  
— id: 34825, year: 1979, vol: 76, page: 5450, stat: Journal Article,