#### Atlas of Genetics and Cytogenetics in Oncology and Haematology

## Arm 21p

## chr21:0-12000000 (12000 Kb)

## Chromosomal abnormalities in band 21p

## References

The human genome used in these documents corresponds to the hg38 (Build GRCh38). A more precise informtion about assemby can be found at Human genome Overview.   
The limits of cytogenetic bands correspond to data from UCSC : cytoBand.txt.gz
  * ISCN Abbreviated Terms and Symbols [NCI]
  * [A]Atlas - Annotated genes 
  * [G]Atlas - Genes implicated in cancer
  * [E] Others genes (Entrez Gene - NCBI)
  * [M] Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer [ CGAP Apr 2018]   
and "Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer" (2012). Mitelman F, Johansson B and Mertens F (Eds.)" [Sept 2016] 
  * [N] Mitelman Database of Chromosome Aberrations (/number)
  * [COS] Catalogue Of Somatic Mutations In Cancer [v85]
  * [COF] Catalogue Of Somatic Mutations In Cancer : Gene Fusions [v85] [PubMed 2017]
  * [CSV] Catalogue Of Somatic Mutations In Cancer : Structural variations (extracted frorm CosmicStructExport.tsv) [v85]) 
  * [CEN] Cancer Gene Census [v85]
  * [TF] TCGA Fusions (MDAndersson) TCGA Fusions (Jackson Lab) [PubMed 2014] (the fusions are limited to tier 1 and 2) 
  * [TIC] TicDB [PubMed 2007]
  * [H2] ChimerDB_2.0 [PubMed 2006] [PubMed 2010] [H3] ChimerDB_3.0 [PubMed 2017]
  * [K] dbCRID [PubMed 2011]
  * [CT] ChiTARS-2.1 [PubMed 2012] [PubMed 2014]
  * [CT] ChiTARS-3.1 [PubMed 2016]
  * [LAI] Fusion transcript loci share many genomic Features with non-fusion loci. Lai et al. BMC Genomics 2015 [PubMed 2015]
  * [PM] Gene Fusions from Pubmed abstract mining


* [L] Fusion gene microarray reveals cancer type-specificity among fusion genes. Lovf M et al.Genes Chromosomes Cancer. 2011 May;50(5):348-57. 
* [S] A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis. Skotheim RI, et al. Mol Cancer. 2009 Jan 19;8:5. 
* [V] ETV6 fusion genes in hematological malignancies: A review. De Braekeleer E. et al. Leuk Res. 2012 May 12. 
* [GT] Cell Lines (Genentech) 
* [FC] Fusion cancer (Beijing) [PubMed 2015] (the fusions are limited to class A and B) 
* [NOR] [PubMed 2016] Babiceanu M et al. Recurrent chimeric fusion RNAs in non-cancer tissues and cells. Nucleic Acids Res. 2016 Feb 2 (Table S3) 
* [URK][PubMed 2016] Urakami et al. Next generation sequencing approach for detecting 491 fusion genes from human cancer. Biomed Res. 2016;37(1):51-62. 
* [AM] [PubMed 2016] Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancersAlaei-Mahabadi B. et al.,Proc Natl Acad Sci U S A. 2016 Nov 16. pii: 201606220. 
* [FM] [PubMed 2018] Genomic hotspots but few recurrent fusion genes in breast cancer, Fimereli et al., Genes Chromosomes Cancer. (SupplTableS2.xls) 2018 Feb 13
* [MA] [PubMed 2018] Pan-cancer genome and transcriptome analyses of1,699 paediatric leukaemias and solid tumours, Ma et al, Nature (March 2018) 
* [GAO] [PubMed 2018] Driver Fusions and Their Implications in the Development and Treatment of Human Cancers. Gao et al, Cell Reports (April 2018)