# Development of a Dynamic Model for the Lung Lobes and Airway Tree in the NCAT Phantom

### Abstract

The 4D NCAT phantom was developed to realistically model human anatomy based on the Visible Human data and cardiac and respiratory motions based on 4D tagged MRI and respiratory-gated CT data from normal human subjects. Currently, the 4D NCAT phantom does not include the airway tree or its motion within the lungs. Also, each lung is defined with a single surface; the individual lobes are not distinguished. We further the development of the phantom by creating dynamic models for the individual lung lobes and for the airway tree in each lobe. NURBS surfaces for the lobes and an initial airway tree model (∼4 generations) were created through manual segmentation of the Visible Human data. A mathematical algorithm with physiological constraints will be used to extend the original airway model to fill each lobe. For each parent airway branch inside a lobe, the algorithm extends the airway tree by creating two daughter branches modeled with cylindrical tubes. Parameters for the cylindrical tubes such as diameter, length, and angle are constrained based on flow parameters and available lung space. The bifurcating branches are propagated within a lung lobe until it is filled. Once each lobe is filled, the cylindrical tubes are converted into NURBS surfaces and blended with the original airway tree obtained through segmentation. The respiratory model previously developed using the respiratorygated CT data is then applied to the surfaces of the lobes and airway tree ω create the new 4D respiratory model. This improved model will provide a useful tool in future studies researching the effects of respiratory motion on lung tumor imaging. It is also an important step in advancing the 4D NCAT for applications in more high-resolution imaging modalities such as x-ray CT.

Original language| English (US)  
---|---  
Title of host publication| IEEE Nuclear Science Symposium and Medical Imaging Conference  
Editors| S. Metzler  
Pages| 1858-1862  
Number of pages| 5  
Volume| 3  
State| Published - 2002  
Event| 2002 IEEE Nuclear Science Symposium Conference Record \- Norfolk, VA, United States  
Duration: Nov 10 2002 → Nov 16 2002  
  
### Other

Other| 2002 IEEE Nuclear Science Symposium Conference Record  
---|---  
Country| United States  
City| Norfolk, VA  
Period| 11/10/02 → 11/16/02  
  
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Dynamic models

Imaging techniques

Magnetic resonance imaging

Tumors

X rays

### Keywords

  * Airway tree
  * Phantom
  * Respiratory motion
  * Segmentation



### ASJC Scopus subject areas

  * Computer Vision and Pattern Recognition
  * Industrial and Manufacturing Engineering



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Garrity, J. M., Segars, W. P., Knisley, S., & Tsui, B. (2002). Development of a Dynamic Model for the Lung Lobes and Airway Tree in the NCAT Phantom. In S. Metzler (Ed.), _IEEE Nuclear Science Symposium and Medical Imaging Conference_(Vol. 3, pp. 1858-1862)

**Development of a Dynamic Model for the Lung Lobes and Airway Tree in the NCAT Phantom.** / Garrity, James M.; Segars, W. Paul; Knisley, Steven; Tsui, Benjamin.

IEEE Nuclear Science Symposium and Medical Imaging Conference. ed. / S. Metzler. Vol. 3 2002. p. 1858-1862.

Research outputChapter in Book/Report/Conference proceeding › Conference contribution

Garrity, JM, Segars, WP, Knisley, S & Tsui, B 2002, Development of a Dynamic Model for the Lung Lobes and Airway Tree in the NCAT Phantom. in S Metzler (ed.), _IEEE Nuclear Science Symposium and Medical Imaging Conference._ vol. 3, pp. 1858-1862, 2002 IEEE Nuclear Science Symposium Conference Record, Norfolk, VA, United States, 11/10/02.

Garrity JM, Segars WP, Knisley S, Tsui B. Development of a Dynamic Model for the Lung Lobes and Airway Tree in the NCAT Phantom. In Metzler S, editor, IEEE Nuclear Science Symposium and Medical Imaging Conference. Vol. 3. 2002. p. 1858-1862

Garrity, James M. ; Segars, W. Paul ; Knisley, Steven  ; Tsui, Benjamin. / **Development of a Dynamic Model for the Lung Lobes and Airway Tree in the NCAT Phantom**. IEEE Nuclear Science Symposium and Medical Imaging Conference. editor / S. Metzler. Vol. 3 2002. pp. 1858-1862

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