open-index/open-wikipedia-markdown huggingface dataset:
Vitamin C

**Vitamin C** (a wɔsane frɛ no ascorbic acid ne ascorbate) yɛ vitamin a etumi sɛe nsuo mu a ɛwɔ citrus ne nnuaba, nnuaba, ne nnuaba afoforo mu. Ɛsan yɛ nnuru a wɔde hyɛ obi nsa, na wɔ aman bi so no wɔtɔn no sɛ nnuane a wɔde ka aduan ho a wontua ho ka. Wɔde di dwuma sɛ aduru a wɔde si scurvy a ɛyɛ yare a vitamin C a enni mu na ɛde ba no ano na wɔde sa yareɛ.
Vinblastine

**Vinblastine** (**VBL**), a wɔtɔn wɔ din Velban ne din foforɔ so, yɛ aduru a wɔde ma obi a ɔyare kokoram, na wɔtae de di dwuma wɔ nnuru afoforɔ ho de sa kokoram ahodoɔ bi. Eyi ka Hodgkin's lymphoma, non-small-cell lung cancer, bladder cancer, brain cancer, melanoma, ne testicular cancer ho. Wɔde fa ntini mu ma. Nnipa dodoɔ no ara nya nsunsuansoɔ bɔne bi. Ɛtae ma obi te nka sɛ ne ho atɔ no, ɔyare, ne ho nyɛ den, ne ho ntɔ no, na ne ti bɔ no. Akwanhyia a ano yɛ den no bi ne mogya mu nkwammoaa a ɛresɛe ne ɔhome a ɛyɛ den. Ɛnsɛ sɛ wɔde ma nnipa a wɔyare mmoawammoawa. Sɛ wode di dwuma wɔ nyinsɛn mu a, ebetumi apira abofra no. Vinblastine yɛ adwuma denam nkwammoaa mu kyekyɛ a ɔbara no so. Wonya Vinblastine wɔ afe 1958 mu. Nhwɛsoɔ bi a ɛda hɔ ma adannandie aduru a wɔayi no ayɛ sɛ aduru a wɔtae de di dwuma no ne vinblastine a mfitiase no na wonya no fi Madagascar periwinkle mu. Wiase Nyinaa Akwahosan Ahyehyɛdeɛ no atwerɛ nnuru a ɛho hia paa no din wɔ so.

## Wɔ nnuruyɛ mu
Vinblastine yɛ nnuru a wɔde sa yareɛ bi, a ebi ne ABVD a wɔde sa Hodgkin lymphoma, ne methotrexate a wɔde sa yare bi a wɔfrɛ no aggressive fibromatosis (desmoid tumor). Wɔde di dwuma nso de sa histiocytosis sɛnea Histiocytosis Association nhyehyɛeɛ kyerɛ.

## Baabi a menyaa mmoa firiiɛ

Nkyekyεmu:Wikipedia
Riboflavin

**Riboflavin**, a wɔsan nso frɛ no  **vitamin B<sub>2</sub>**, yɛ vitamin a wɔtumi nya no aduane mu anaa wɔtumi nya no nnuro mu.  coenzymes, atitire mmienu na ɛde Riboflavin ba. Ɛnonom ne flavin mononucleotide ne flavin adenine dinucleotide. Ɛyɛ aduro a ɛtumi nane wɔ nsuo mu. Ɛyɛ B vitamins nnuane nnuro nkorabata no mu baako. ɛnte sɛ  folate ne vitamin B6, a yɛtumi nya wɔ nneɛma bi te sɛ vitamers. 
## Ne Dwumadie

Wɔde sacorneal yadeɛ. Deɛ ɛde corneal ectasia ba no ne  Keratoconus. 
## Beaeɛ a Menyaa Mmoa Firiiɛ
Vincristine

Vincristine a wɔsan frɛ no leurocristine na wɔtɔn no wɔ din Oncovin ne afoforɔ nso, ɛyɛ nnuru a wɔde sa kokoram yareɛ ahodoɔ pii.Deɛ ɛka wei ho ne mogya mu kokoram a ɛmu yɛ den, myeloid mogya mu kokoram a ɛmu yɛ den, Hodgkin yareɛ, neuroblastoma, ne nkwammoaa nketenkete ahurututu mu kokoram ne afoforɔ.Wɔde fa ntini mu na ɛma.

## Dwuma a wɔde di
Deɛ wɔde di dwuma titiri yɛ Hodgkin lymphoma sɛ nnuru a wɔde sa yareɛ no fa CHOP R-CVP, Hodgkin lymphoma sɛ MOPP fa, COPP, BEACOPP, anaasɛ Stanford V nnuru a wɔde sa yareɛ a ɛnyɛ deɛ agye din kɛseɛ wɔ acute lymphoblastic leukemia ne nephroblastoma ayaresa mu.
Pantothenic acid

Pantothenic acid (vitamin B5) wɔsane frɛ no B vitamin no yɛ nnuane nnuro a ɛho hia yie. Mmoa nyinaa hia pantothenic acid de yɛ coenzyme A (CoA), a ɛho hia ma nkwammoa ahoɔden ne protein, carbohydrates, ne honam mu sradeɛ.

## Nkyerɛaseɛ

* Pantothenic acid yɛ vitamin a ɛtumi sɛe wɔ nsuo mu, ɛyɛ B vitamin ahodoɔ no mu baako. Ɛfiri amino acid β-alanine ne pantoic acid mu na ɛyɛ no (hwɛ coenzyme A biosynthesis and structure figures).
Thiamine

Thiamine a wɔsan frɛ no thiamin ne vitamin B1 yɛ vitamin, aduannuro nketenkete a ɛho hia ma nnipa ne mmoa. Wohu no wɔ aduane mu na wɔsane wɔ bi a wayɛ ɛtɔn sɛ ɛyɛ aduane nnuro a wɔde ka aduane ho anaa aduro. Thiamine ahodoɔ a phosphorylated womu ho hia ma nipadua mu nneɛma bi a ɛma nipadua no yɛ adwuma, a glucose ne amino acids a ɛpaapae ka ho.

Aduane a thiamine ɛwɔ mu  bi ne aburo a wɔayam, atoko, ne nam ne mpataa bi. Sɛ wɔyɛ aburo a, eyi vitamin a ɛwɔ mu no pii firi hɔ, enti wɔ aman pii mu no, wɔde thiamine ahyɛ aburo ne esam mu ma. Nnuro a wɔde ka ho ne nnuro a wɔde sa thiamine a enni nipadua mu ne ɔhaw ahodoɔ a efiri mu ba te sɛ beriberi ne Wernicke amemene mu yare na esi ano. Wɔde sa maple syrup nsu mu yare ne Leigh syndrome nso. Wɔtaa nom nnuro a wɔde ka aduane ho ne nnuro a wɔde ma wɔ ano, nanso wobetumi de nnuro a wɔde fa ntini mu anaa ntini mu nso ama.
Niacin

Niacin,a wɔsan frɛ no nicotinic acid, yɛ nneɛma binom a ɛka vitamin B3 ho,nnuanenuro a ɛyɛ ma nipadua no.Nnua ne mmoa ahodoɔ na ɛde ba.

## Ne Nkyerɛkyerɛmu
Nacin yɛ nnuanenuro a ɛho hia pa ara, a wɔtɔn no sɛ nnuanenuro a ɛboa nipadua no na US nso wɔtɔn no sɛ aduro.

## Vitamin a ɛnni nipadua no mu
Sɛ niacin nni aduane a wodi mu a,ɛde yareɛ a    wɔfrɛ no pellagra na ɛba,a ɛde ayamtuo,na wedeɛ no ani nso yɛ duru.

## Faako a Ɛfiri
Wobɛhunu nacin wɔ nnuane ahodoɔ mu a nnuane a wɔahyɛda de agu biribi mu ka ho,nam a ɛfiri mmoa ahodoɔ mu,po nnuane, ne nneɛm binom a wɔde yɛ aduane.

## Wɔayɛ no sɛ nsuo de sa Yareɛ
Sɛ wokɔ United States a,niacin a wɔagye ato mu no,wɔde sa yareɛ bi te sɛ hyperlipidemia ne hypertriglyceridemia.

## Abakɔsɛm
Wɔdii kan kyerɛkyerɛ Niacin mu wɔ 1873 a Hugo Weidel na ɔyɛeɛ wɔ nadesua a ɔyɛɛ wɔ  nicotine mu no nanso ɛdii mfeɛ beberee a na ɛho hia kyɛn protein, fat ne carbohydrates a na ɛho hia ma nipadua no.

## Nhwehwɛmu
Wɔ mmoa mu ne vitro mu no,niacin de nneɛma ahodoɔ binom na ɛba nipadua no mu.

## Beaeɛ a Menyaa Mmoa Firiiɛ
Vardenafil

**Vardenafil yɛ aduro a sɛ wokɔ dwa so a edin a ɛdeda so ne**  **Levitra** ne deɛ ɛkeka ho. Ne dwuma titire pa ara ne sɛ ɛsa nna mu yareɛ bi te sɛ kɔtewuiɛ.  Sɛ mpo onipa no kɔte mpo nnuiɛ na sɛ adwuma na ɔntumi mmɔ wɔ mpa mu yie nso a, wɔwɔ kwan a wɔfa so de aduro no di ho dwuma. Wɔtumi no. Ɛsiane sɛ ɛtumi nane wɔ nsuo mu.

## Ne Dwumadie
Vardenafil dwumadie ne  tadalafil (Cialis).  Nsonsonoeɛ a ɛda  mu ne sɛ sɛdeɛ  wɔn mu biara nitrogen nhyehyɛeɛ teɛ.  Tadalafil bɔberɛ da nso firi  sildenafil ne  vardenafil deɛ ho.

## Nsunsuansoɔ
Sɛ obi fa a, nsunsuansoɔ no bi ne PDE5 inhibitors deɛ ssesɛ. Nsunsuansoɔ no bi ne abofono, yafunukeka,  akyiyadeɛ, honam ani nsaa ne ahokeka. 

## Beaeɛ a Menyaa Mmoa Firiiɛ
Valsartan/hydrochlorothiazide

**Valsartan/hydrochlorothiazide**, a wɔtɔn no wɔ din Diovan HCT mu no yɛ aduru a wɔde di mogya mmorosoɔ yareɛ berɛ a valsartan nyɛ adwuma yie. Ɛyɛ valsartan, a ɛyɛ angiotensin receptor blocker ne hydrochlorothiazide, a ɛyɛ diuretic, a wɔaka abom. Ɛyɛ aduro wɔnom.

## Nhyehyɛeɛ - Dwumadie Nkitaho

* Valsartan wɔ ARB dodoɔ no ara wɔ biphenyl kuo a ɛtrɛ ne tetrazole a edi karboxylate kuo no akyi sɛ bioisostere nanso ɛnhyɛ metabolic inactivation koro no ara mu.Ade titire a ɛsɛ sɛ wohyɛ no nso wɔ mmoawammoawa no ho ne sɛdeɛ ɛsono angiotensin receptor blockers afoforɔ no, ne sɛ mmoawammoawa no wɔ 2-prime gyinabea no wɔ tetrazole, a hydrogen a ɛyɛ acid wɔ ho.
Vancomycin

**Vancomycin** yɛ glycopeptide antibiotic aduro a wɔde di dwuma de sa yareɛ mmoawa bi yare. Wɔde di dwuma wɔ ntini mu (wɔnam ntini mu) sɛ aduro a wɔde sa honam ani yareɛ, mogya mu yareɛ, endocarditis, nnompe ne ntini mu yareɛ, ne methicillin-resistant Staphylococcus aureus na ɛde ba no. Wobɛtumi asusu mogya mu nnuro no dodoɔ a ɛsɛ sɛ wode di dwuma yie no. Vancomycin nso yɛ no ano mu (nam ano so) sɛ aduru a wɔde sa Clostridium difficile colitis a ɛyɛ den. Sɛ wɔde ano di a, wɔnnwene no yie.

## Nsunsuansoɔ a ɛwɔ ho

### Nnurunom
Deɛ ɛtae ba wɔ vancomycin a wɔde di dwuma ano no mu (a wɔde di dwuma de sa ɔyare mmoawa) yɛ dea edidi so yi: 

* ɔyare mmoawa a ɛwɔ ɔyafunu mu (te sɛ yafunu mu yaw ne nsamanwa); 
* dysgeusia (nidi a ɛyɛ hu), bere a wɔde vancomycin ano aduru di dwuma no, nanso ɛnyɛ bere a wɔde vancomycin kapsula di dwuma no..

## Baabi a menyaa mmoa firiiɛ
Biotin

**Biotin** (wɔsane frɛ no **vitamin B<sub>7</sub>** anaa **vitamin H**) yɛ vitamin B ahoɔden nnuro no mu baako. Wɔtaa de dwuma wɔ ayaresa kwan ahodoɔ pii mu. Ɛdin *biotin* no firii German kasa no mu na wɔfa firii tete Greek asɛmfua βίοτος (*bíotos  a ɛkyerɛ nkwa) ne asɛmfua nsiakyire*  "-in" a wɔtaa de dwuma wɔ abɔdeɛ mu nyansapɛ mu de kyerɛ sɛ biribi rehyehyɛ). Biotin ahosuo yɛ fitaa na ne su ayɛ sɛ panneɛ a ani da hɔ.

## Ne su wɔ abɔdeɛ mu nyansapɛ mu.
Wɔbu aduro yi sɛ ɛka heterocyclic compound a sulfur-containing tetrahydrothiophene aka ho na ɛka ureido kuo no ho. Saa uriedo kuo yi a ɛwɔ −N−CO−N− no na ɛfa carbon dioxide mframa wɔ carboxylation dwumadie mu.
Folate

**<mark>Folate</mark>**, din a 3toso y3 **vitamin B<sub>9</sub>** 3ni **folacin**, 3ka B vitamins.hwo .F**olic acid a yay3**  dani folate we y3 nipadua mu.  Y3 nnipadua ehia folate de ay3 DNA ni RNA. Saa vitamin wei eni nnipadua ni mu a entumi di dwuma yie Ewc nnduane bebree emu.

## ABAKCSEM
Abcdie mu nyasafuo egyidi s3 folate in nnipadua mu eni anemia 3y3 p3. 3wc afe 1931,  Lucy Wills y3 nhwehwemu ehwu s3 folate hwo hia ma apenfuo paa.

## BEBIA MMOA EFIRI
Vildagliptin

Vildagliptin, a wɔato wɔ din Galvus ne afoforɔ ase no yɛ aduro a wɔde ano nom (aduro a ɛko tia asikreyareɛ) a ɛwɔ dipeptidyl peptidase-4 (DPP-4)  nnuro a ɛsi ano no mu. Vildagliptin si GLP-1ne GIP a ɛnyɛ adwuma denam DPP-4 so no ano, na ɛma GLP-1 ne GIP tumi ma insulin a ɛwɔ beta nkwammoa no mu no yɛ kɛse na ɛsi glucagon a efi alpha nkwammoa a ɛwɔ no mu no ano . Langerhanfo nsupɔ a ɛwɔ dwensɔtwaa mu.

EMA in 2007 na wɔgye too mu.
Vitamin B12

**Vitamin B<sub>12</sub>**, a wɔsan nso frɛ no  **cobalamin**, ɛyɛ nnuane nnuro a ɛtumi nane wɔ nsuo mu a ɛboa nsiesie. Ɛyɛ B Vitamin nnwɔtwe no mu baako. Ɛhia ma mmoa, a yɛde  yɛ mmoa ka DNA  ho, ɛne fatty acid ne amino acid nsiesie. Ɛhoo hia wɔ nɛɛvɔs a brɔfo kasa mu no wɔfrɛ no nervous system adwuma yɛ ne kwan so wɔ myelin no adwuma yɛ mu, ɛne sɛkuletiri a brɔfo kasa mu no wɔfrɛ no circulatory system ɛwɔ red blood cells wɔ nnompe mu. Nnua ɛnhia cobalamin ne nneyɛɛ ka enzymes ho a wɔnna wɔn ho no so.
Vildagliptin/metformin

Vildagliptin/metformin a wɔtɔn no wɔ din Eucreas, ne afoforɔ no yɛ aduru a wɔde sa asikyireyareɛ a ɛyɛ type 2 a wɔaka abom a wɔahyɛ da ayɛ. Wɔpenee so sɛ wɔmfa nni dwuma wɔ Europa Aman Nkabom no mu wɔ Obubuo bosom no mu afe mpem mmienu ne nson (November 2007) mu, na wɔsan penee so bio wɔ afe mpem mmienu ne nwɔtwe (2008) mu.
Valsartan

Valsartan,a Diovan ne nnipa ahodoɔ binom tɔn no,yɛ aduro a wɔde sa mogyaborɔsoɔ, akomayareɛ, ne  sawa mu yareɛ. Ɛka nnuro a wɔfrɛ no angiotensin receptor blockers(ARBs) ho.

## Yareɛ Ahodoɔ A Ɛsa
Wɔde Valsartan sa mogyaborosoɔ,akomayareɛ,na afei ɛte nnipa binom a wɔn akoma benkum no yɛn wɔn ya no.

## Ɛho Nsunsuansoɔ
Ɛho nsunsuansoɔ no gyina sɛdeɛ wɔde aduro no saa yareɛ no.

## Asetena ne Amammerɛ
Wɔ 2010, wɔtumi tɔn Valsartan ɔpepepem $2.052 wɔ United States ne ɔpepepem $6.053 wiase afanaa nyinaa.

## Beaeɛ A Menyaa Mmoa Firiiɛ
Tranexamic acid

**Tranexamic acid** yɛ aduro a wɔde di dwuma de sa yareɛ anaa ɛbɔ mogya a ɛyera pii a ɛfiri yawdie kɛseɛ, awoɔ akyiri mogya, oprehyɛn, ɛse a wɔtwe, ne mogya a ɛfiri nan mu, ne berɛ tenten a obi wɔ no ho ban. Wɔsane de di dwuma wɔ angioedema a wonya firi awoɔ mu mu nso. Wɔfa no ano mu, fa w'aduru no kɔ wo ntini mu, anaa fa w'aduru no kɔ wo ntini mu.

## Ne dwumadie

### Nnuruyɛ dwumadie
Wɔtae de tranexamic acid di dwuma bere a obi anya ɔhaw kɛse bi no. Wɔde tranexamic acid di dwuma de siw mogya a ɛyera wɔ tebea horow te sɛ ɛse ho adwuma a wɔyɛ, mogya pii a efi awo mu ba, ne oprehyɛn a mogya pii bɛtumi afi mu aba ano.

## Baabi a menyaa mmoa firiiɛ
Trichloroacetic acid

**Trichloroacetic acid** (**TCA**; **TCAA**; din foforɔ ne **trichloroethanoic acid**). Nneɛma mmiɛnsa na ɛkeka bobom yɛ trichloroacetic acid. Ɛnonom ne  hydrogen methyl ne chlorine.  T**richloroacetates nso yɛ ne nkorabata no bi**.
## Ne Dwumadie
Wɔ  biochemistry mu no, wɔde di  proteins, DNA, ne RNA ho dwuma.  Wɔde TCA  DCA nyinaa yɛ nku ahodoɔ; deɛ ɛtumi sa honam ani yadeɛ ne deɛ ɛma honam no ani yɛ fu nso.

## Beaeɛ a Menyaa Mmoa Firiiɛ
Clindamycin/tretinoin

Clindamycin/tretinoin yɛ gɛle a wɔde sa honam ani nsaawa yareɛ ne titire anim nsaa. Nnuru no mu mmienu ne clindamycin phosphate (1.2%) ne tretinoin (0.025%) a wɔsan nso frɛ no retinoid. Clindamycin no yɛ adwuma tia gram- positive mmoawa, a streptococci ne staphylococci a wɔko tia penicillin ka ho.

Tretinoin no tumi sɛe sradeɛ dodoɔ a honam no mu ntini no ma no, na ɛsan nso hyɛ honam no nkwammoaa no ho nkuran. Wɔde nnuru a wɔde ma wɔ baabi a ɛsɛ sɛ wɔkora so no hyɛ 2, 30, ne 60 gram ntoa mu, na ɛsɛ sɛ wɔkora so wɔ 25°C (77°F), na wɔkata ntoa no so yie na wɔde to baabi  hann amma nni.

Deɛ ɛnyɛ wɔ ho no bi ne sɛ ɛma honam a ɛpopɔ, kɔbere a ayɛ kɔkɔɔ, kuro, honam keka ne mfonitwa ho atenka. Afei nso, clindamycin a wɔde di dwuma wɔ baabi no bɛtumi ama yareɛ a wɔfrɛ no diarrhea anaa colitis aba. Sɛ obi de aduru yi gu awia mu a, ɛbetumi ama ne honam ani akeka no.
Travoprost

**Travoprost**, a wɔtɔn no wɔ **Travatan** din mu wɔ afoforɔ mu, yɛ aduro a yɛde sa mmogya mmorosoɔ wɔ ani mu a ɛtɛ ka ho. Ne titire, yɛde sa ɛyɛ a emu abue sɛ deɛ yɛde yɛ no nso a. Yɛde gu yɛn ani so. Nsunsuansoɔ biara si wɔ dɔnhwere mmienu ntɛm. Nsunsuansoɔ kɛkɛ bi ne ani a ayɛ kɔkɔɔ, ani a etwa nkyene, ne ani a asesa n'ahosuo. Nsunsuansoɔ ɛho hia paa bi ne ɛyɛ. Ɛnyɛ sɛ wɔfa no nnyinsɛn ne nnufoɔ ma berɛ mu.
Sacubitril/valsartan

**Sacubitril/ valsartan** a watɔ ne din wɔ **Entreso** ase, ɛyɛ aduro a wayɛ ankasa ama nnuro a wayɛ ama akoma yareɛ. Ɛkura neprilysin inhibitor sacubitril ne angiotensin receptor blocker valsartan.
Tramadol

**Tramadol** a wɔde ɛdin **Ultram** ne deɛ ɛkeka ho na ɛtɔn, yɛ aduro a wɔde sɔ yaw a ano yɛ den anaa adwenedwene *(serotonin–norepinephrine reuptake inhibitor (SNRI)* ano kakra. Sɛ wonom fa w'anom a, yaw a worefa mu no ano firi aseɛ ba fam bɛyɛ nnɔn hwere baako akyi. Wɔtumi de fa ntini de ma ɔyarefoɔ no nso. Wɔtaa de paracetamol *(acetaminophen)* ka ho wɔ ne n'ayaresa dwumadie mu.

Ɔhaw ahodoɔ a aduro yi tumi de ba ne ayamtim, ahokeka ne abofono.
Diego Maradona

**Diego Armando Maradona** (30 Ɔkɔtɔberɛ 1960 – 25 November 2020) yɛ Argentina bɔɔlbɔfo a wɔde no bu kɛse wɔ agumadi abakɔsɛm mu. Wɔka no ho sɛ ɔyɛ agodifo titiriw, na ɔyɛɛ nnipa baanu mu baako a wɔwɔ FIFA Agumadi a Ɔsen Biara wɔ Afeha a Ɛto so 20 mu abasobɔde no.

Maradona yɛ playmaker a ɔyɛ adwuma wɔ classic number 10 bepɔw no mu. Ne anisoadehu, passing, bɔɔl akyekyɛde, ne dribbling ahokokwaw kaa ne tenten ketewaa ho, maa no yɛɛ adwuma yiye sen agodifo afoforo pii. Ne akanni wɔ abɔnten so maa ne kuw di nkɔso, na ɔwɔ aniwa a ɔde hwɛ bɔɔl ne free kick tumi kɛse. Na ɔyɛ talente a onya ntɛm, enti wɔfrɛ no "El Pibe de Oro" ("The Golden Boy").

Maradona yɛ onipa a odi kan a ɔde wiase kyerɛwtohɔ sii hɔ mprenu wɔ sika ho: wɔ 1982 mu kɔɔ Barcelona gyee £5 ɔpepem, ne 1984 mu kɔɔ Napoli gyee £6.9 ɔpepem. Ɔdii agorɔ maa Argentinos Juniors, Boca Juniors, Barcelona, Napoli, Sevilla, ne Newell's Old Boys. Ɔyɛɛ din kɛse wɔ Napoli, dii nkonim pii, na wɔdii Serie A title mprenu. Nanso, ɔhaw kaa no wɔ abɔnten so, na ne bere wɔ Napoli baa awiei wɔ ɔhaw a ɛfa cocaine ho.

Wɔ Argentina amanaman ntam adwuma mu, Maradona nya 91 caps na ɔbɔɔ 34 bɔɔl. Ɔbɔɔ bɔɔl wɔ FIFA Wiase Kupɔn anan mu, na wɔ 1986 Mexico Wiase Kupɔn mu, ɔyɛɛ Argentina panyin na odii wɔn anim dii West Germany so nkonim, nyaa Sikakɔkɔɔ Bɔl sɛ bɔɔlbɔfo a ɔsen biara. Wɔ 1986 Wiase Kupɔn mu, ɔbɔɔ bɔɔl abien tiaa England 2-1; nea edi kan yɛ "Nyame Nsa" foul, ne nea ɛto so abien no yɛ dribble a ɛtwam 60 m a wɔfrɛɛ no "Goal of the Century".

Maradona became the coach of Argentina's national football team in November 2008. He was in charge of the team at the 2010 World Cup in South Africa before leaving at the end of the tournament. He then coached Dubai-based club Al Wasl in the UAE Pro-League for the 2011–12 season. In 2017, Maradona became the coach of Fujairah before leaving at the end of the season. In May 2018, Maradona was announced as the new chairman of Belarusian club Dynamo Brest. He arrived in Brest and was presented by the club to start his duties in July. From September 2018 to June 2019, Maradona was coach of Mexican club Dorados. He was the coach of Argentine Primera División club Gimnasia de La Plata from September 2019 until his death in 2020. He was ranked as the third best all time football player by *FourFourTwo*.
Trihexyphenidyl

Trihexyphenidyl (THP, benzhexol, trihex, a wɔtɔn sɛ Artane ne afoforo) yɛ aduru a ɛko tia yareɛ a ntini yareɛ, awosoɔ, akisikuru (spasms), ne ntini a ɛntumi nni dwuma yie. Ɛyɛ aduru a ɛwɔ antimuscarinic kuo no mu na wɔtaa de di dwuma de boa Parkinson yare no ho dwuma.
Tretinoin

Tretinoin, a wɔsan frɛ no all-trans retinoic acid(ATRA),yɛ aduro a wɔde sa nsaanini ne yareɛ kokoram. Nsaanini deɛ, wɔde yɛ wedeɛ no ani te sɛ nku no. Na kokoram yareɛ deɛ, ɛtumi yɛ adwuma sɛ RARA-PML  wɔ hɔ a wɔde fa anomu.

## Yareɛ A Wɔde Sa

### Wedeɛ

### Nsaanini
Yareɛ a wɔde tretinoin sa pa ara ne nsaanini.Adesua ahodoɔ nso boa retinoids a wɔde sa nsaanini.

## Nsunsuansoɔ
Wɔde tretonoin sa wedeɛ ani yareɛ nko ara na ɛnsɛ sɛ wode yɛ ani so anaa sɛ nipadua no apɔ so.Ɛho nsunsuansoɔ pa ara ne wedeɛ no ani a ɛbɛtwintwam,kɔkɔɔyɛ,ahonhono.

## Abakɔsɛm
James Fulton ne Albert Kligmamwhen a wɔwɔ Pennsylvaniani suapɔn mu wɔ 1960s no mu na wɔyɛɛ saa aduro yi de saa nsaanini.

## Farebae
Baabi a wɔnyaa tretinoin firiiɛ no,wɔnnim.Ɛwom akwan ahodoɔ bebree na aba sɛ wɔde bɛhunu.

## Beaeɛ A Menyaa mmoa Firiiɛ
Tolbutamide

**Tolbutamide** yɛ aduro a wɔde sa Asikyire yadeɛ bi a yɛfrɛ no type 2 diabetes. Tolbutamide pu nsuo bi a yɛfrɛ no insulin. Nipadua no akwaa bi a frɛ no pancreas mu na insulin wɔ.( Pancreas) wɔ yafunu mu. Ɛsiane sɛ obi fa tolbutamide a akyire nsunsuansoɔ no bi nhyɛ da nyɛ adeɛ a wɔn ani gye ho nti, wɔntaa mfa. Ɛnte sɛ afoforɔ bi a ɛnnɛ yi wɔtaa de di dwuma mu. Nhwehwɛmu kyerɛ sɛ mpanimfoɔ na ɛtaa yɛ ma wɔn pa ara . Afe Apem, ahankron ne aduonum nsia no mu na wɔhunuiɛ.
## Nsunsuansoɔ
Sɛ obi fa aduro yi a, ɛso nsunsuansoɔ no bi ne sɛ ɛma no yɛ kɛseɛ.

## Beaeɛ a Menyaa Mmoa Firiiɛ
Verapamil

**Verapamil**, edin a y3di fr3 no a nnipa bebree naa nnim y3, calcium a y3di sc mogya mmrosuc ano. Y3di sc etipae a ano edin ano. Eduro wei y3num anaa s3 y3 wc ni pane3 3fa y3 ntini mu.

## DWUMA A EDI
Verapamil 3y3 editor an y3 de sc angina(chronic stable, vasospastic or Prinzmetal variant), unstable angina (crescendo, preinfarction) ano , y3 san de si paroxysmal supraventricular tachycardia ano.

## BEBIA MMOA EFIRI
Tramadol/paracetamol

**Tramadol/ paracetamol** a ɔsane frɛ no tramadol/ acetaminophena watɔ ne din wɔ  **Ultracet**  ne nkeka ho, ɛyɛ aduro a w'akabom a ɔde yɛ bra yaw ano. Ɛkura tramadol, a ɛyɛ hydrochloride a ɛyɛ analgesic ne paracetamol a ɛyɛ analgesic. Yɛnom fa yanum.
Tocilizumab

**Tocilizumab**, a wɔtɔn no wɔ **Actemra** din mu, yɛ aduro na ɛboa nipadua no ma ɛko tia nyarewa, wɔde di rheumatoid arthritis, systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, giant cell arteritis, cytokine release syndrome, COVID-19, ne systemic sclerosis-associated interstitial lung disease (SSc-ILD) ho dwuma. Ɛyɛ monoclonal antibody a wɔde di interleukin-6 receptor (IL-6R) so. Interleukin 6 (IL-6) yɛ cytokine bi a ɛboa kɛse wɔ nipadua mu nipadua no ho banbɔ mu, na ɛboa ma nyarewa pii te sɛ autoimmune yare, multiple myeloma ne prostate cancer ba. Osaka Sukuupɔn ne Chugai yɛɛ tocilizumab, na Hoffmann-La Roche maa no tumi krataa wɔ afe 2003 mu.

## Baabi a menyaa mmoa firiiɛ
Amlodipine/valsartan

Amlodipine/valsartan a woato ne din Exforge ase ne afoforɔ no yɛ aduro a wɔaka abomu a ɛte mogya mmorosoɔ so. Ɛwɔ amlodipine, sɛ besilate, dihydropyridine-type calcium channel blocker, ne valsartan, angiotensin II receptor antagonist. Saa nkabomu yi taa yɛ nea wotumi gyina ano yiye na etu mpɔn ma mogya mmorosoɔ a ɛso te.

Wɔpenee so sɛ wɔmfa nni dwuma wɔ aduroyɛ mu wɔ United States wɔ June 2007 mu.

Wɔsan nso wɔ nkabom no a hydrochlorothiazide (Exforge) ka ho HCT), ma nnipa a wohia nnuro mmiɛnsa a wɔde di dwuma na ama wɔatumi ahwɛ wɔn mogya mmorosoɔ so. Wɔpenee so sɛ wɔmfa nni dwuma wɔ aduroyɛ mu wɔ United States wɔ Oforisuo 2009 mu.
Triamcinolone

Triamcinolone yɛ glucocorticoid a wɔde sa honam ani nyarewa bi, ne akisikuro ne afoforɔ. Wɔde si ayamtu ne COPD nso ano. Wobetumi afa akwan ahodoɔ so a deɛ ɛka ho ne ano, wɔde twitwi ntini mu, ne deɛ wɔhome.

Nneyɛe bɔne a ɛtaa ba berɛ a wɔde di dwuma berɛ tenten no bi ne nnompe mu yadeɛ, aniwa a ɛyɛ mmerɛ, akisikuro, ne ntini mu mmerɛyɛ. Nsunsuansoɔ bɔne a anibere wom betumi ayɛ adwene mu yare, asiane a ɛkɔ soro sɛ wobenya ɔyare mmoawa, adrenal suppression, ne bronchospasm. Mpɛn pii no, sɛ wɔde di dwuma wɔ nyinsɛn mu a, asiane biara nni ho. Ɛyɛ adwuma denam ɔfe ne nipadua mu ahoɔden a ɛko tia nyarewa dwumadie a ɛso te so.

Wɔmaa triamcinolone tumi krataa wɔ afe 1956 mu na wɔde dii dwuma wɔ aduroyɛ mu wɔ afe 1958 mu. Wobetumi anya bi sɛ aduro a wɔde yɛ nnuro a wɔde di dwuma wɔ kwan a ɛfata so. Wɔ afe 2021 mu no, na ɛyɛ nnuro a ɛtɔ so 104 a wɔtaa kyerɛ ma wɔ United States, na wɔkyerɛw bɛboro ɔpepem nsia.
Tinidazole

**Tinidazole** a wɔde ɛdin *Tindamax* ne deɛ ɛkeka ho yɛ ayaresa aduro a wɔde ko tia protozoan nyarewa ahodoɔ. Saa aduro yi agye din paa wɔ Europa mantam ne aman ahodoɔ a afei na wɔretu mpɔn mu pa ara. Wɔ saa amantam ahodoɔ yi mu no, wɔde sa anaerobik amoebik ne nyarewa a mmoawammoawa nketekete de ba no. Wɔyɛɛ no afe 1972 mu na ɔka *nitroimidazole antibiotic class nnuro no ho.* Aduro yi, wɔde aka nnuro a ɛho hia pa ara a Wiase Nyinaa Ayaresa Adwumakuo ka ho asɛm *(World Health Organization's List of Essential Medicines).*
Tizanidine

**Tizanidine**, a wɔtɔn no **Zanaflex din mu no yɛ** alpha-2 (α2) adrenergic receptor agonist, a ɛne clonidine ɛsɛ, a yɛde sa nnompe mu kyimatoɔ a efiri akyi dompe mu yaw, sclerosis ntoatoasoɔ ne spastic cerebral palsy. Nsunsuansoɔ ɛba te sɛ baclofen anaa sɛ diazempam. Yɛnom.
Timolol

Timolol yɛ akwansideɛ aduro a wɔde fa anomu anaa sɛ wɔde gu ani so.Sɛ wɔde gu ani so a,na ɛyɛ sɛ ano ayɛ den.

## Yareɛ a ɛsa

### Anomu
Sɛ ɛyɛ anomu a, 

* wɔde sa mogyaborosoɔ

* Wɔde bɔ akomayareɛ ho ban

* wɔde si tipaeɛ ano

## Nsunsuansoɔ
Ɛho nsunsuansoɔ a ano yɛ den pa ara bi ne arrhythmias ne bronchospasms.

## Kuo din
Wɔtɔn timolol wɔ wiase afanaa nyinaa.Timolol a wɔde sa ani yareɛ no deɛ Istabol ne nnwumakuo ahodoɔ binom na wɔtɔn.

## Beaeɛ A Menyaa Mmoa Firiiɛ
Tiabendazole

**Tiabendazole** (INN,BAN) a ɔsane frɛ no **thiabendazole** (AAN,USAN) anaa **TBZ** ne n'adetɔn din ne Mintezol, Tresadem ne Arbotect yɛ deɛ ɔde seisei nnuro no, a antifungal ne antiparastic dwumadifoɔ
Latanoprost/timolol

Latanoprost/Timolol, a woato no din Xalacom a ɛkyerɛ sɛ aduro a wɔde ka bomu a wɔde sa glaucoma, a ɛyɛ latanoprost (akɔ soro uveoscleral outflow of aqueous humor) ne timolol (a beta blocker decreasing the production of aqueous fluid).

## Ɔmanfoɔ ne Amammerɛ

### Edin a ɔda so
Tetracycline

**Tetracycline**, a wɔtɔn wɔ din ahodoɔ so, yɛ aduro a wɔde ano di a ɛwɔ tetracyclinesabusua mu, a wɔde di nyarewa ahorow bi ho dwuma, a ebi ne ntontom, ɔyare a wɔfrɛ no cholera, brucellosis, ɔyaredɔm, atiridiinini, ne ayamtunini.

Deɛ ɛtaa ba no bi ne ɔkwaw, ɔyare a ɛma obi ho kyere no, ɔyare a ɛma obi ho kyere no, ne akɔnnɔ bɔne. Akwanhyia afoforo bi nso ne sɛ mmɔfra a wonnya nnii mfeɛ nnwɔtwe a wɔde di dwuma no mma wɔn nsononoe nyɛ kɛse, wɔyare ayare, na owia tumi hyew wɔn ntɛmntɛm. Berɛ a obi nyinsɛn no, ɛbetumi apira abɔfra no. Ɛyɛ adwuma denam mmoawammoawa mu ahoɔdennuro a wɔhyehyɛ no so.

## Nnuruyɛ mu dwumadie

### Ɛmu yareɛ dwumadie
Tiotropium bromide

Tiotropium bromide a wɔsan nso frɛ no Spiriva wɔ edin foforɔ a ɛno ne bronchodilator (LAMA: long acting muscarinic antagonist) a wɔde di dwuma wɔ nsamanwa mu yareɛ (COPD) ne asthma ho. Ne titire no, wɔde di dwuma berɛ a ɔhome mu yɛ den no de si ano sɛ ɛrenyɛ den, sen sɛ ebesi home no ano.  Wode fa ano mu na etumi de di dwuma. Mpɛn pii no, ɛfiri aseɛ wɔ nnɔnhwere fa mu na ɛtumi di bɛyɛ nnɔnhwere 24.

## Dwuma a yɛde di

* Tiotropium yɛ ade a wɔde di dwuma sɛ aduru a ɛboa ma obi nya atiridii a ɛma wɔhunu ntini wɔde aduro fa mu no.Yɛbɛtumi nso de adi dwuma sɛ adaka mu aduru wɔ nnipa a wɔn yareɛ yɛ asomasɛm a emu yɛ den na wɔn nsa ka corticosteroid (ICS) a wɔfa no mu no. Nanso, wɔnnye ntom sɛ wɔde bɛsa COPD yareɛ anaa asthma yareɛ mu.
Tropicamide

**Tropicamide** a watɔ no wɔ din **Mydriiacyl** ase ne ne nkeka ho, ɛyɛ  aduro a ɔde buei ani na ɛboa ma ɔyɛ ani ho nhwɛhwɛmu. Ɔde yɛ boa yɛ nhwɛhwɛmu wɔ wani no akyi.

## Aduro ne dwumadie
Tromicade yɛ antimuscarinicaduro a ɛyɛ ɔyɛ mydriasis tiawa ne cycloplegia berɛ a ɔde agu ani so. Ɔde di dwuma boa ma nhwɛhwɛmu wɔ lens, bitreous, humor, ne retina ho.
Dorzolamide/timolol

Dorzolamide/timolol, a wɔtɔn no wɔ brand din Cosopt ne afoforɔ ase no yɛ aduru a wɔde sa nhyɛsoɔ a ɛkɔ soro wɔ aniwa no mu a glaucoma ka ho. Ɛyɛ dorzolamide hydrochloride ne timolol maleate a wɔaka abom. Wobɛtumi de adi dwuma berɛ a beta blocker te sɛ timolol nkutoo nnɔɔso. Wɔde di dwuma sɛ aniwa aduru.
Celecoxib/tramadol a wɔde di dwuma

**Celecoxib/tramadol** a wɔtɔn wɔ **Seglentis** din no, yɛ nduru ahodoɔ anoɔden a yɛakeka abom mu (Celecoxib/tramadol) a yɛ de ɛkotia yareɛ mmoawa ne opioid tramadol a wɔde ɛkotia ɛyaw.
Tofacitinib

Tofacitinib a wɔtɔn wɔ din a ɛyɛ Xeljanz ne afoforɔ no yɛ aduru a wɔde sa ntini mu yareɛ, psoriatic arthritis, ankylosing spondylitis, polyarticular (course juvenile) idiopathic arthritis, ne ulcerative colitis. Nneɛma bɔne a ɛtaa ba ne akisikuru, ti yareɛ ne mogya mmoroso. Ebia nneɛma bɔne bi te sɛ nyarewa, kokoram, ne ahurututu mu ntini a ɛma mogya tu. U.S. Aduan ne Nnuru Dwumadibea (FDA) nso de kɔkɔbɔ ahodoɔ a ɛfa asiane a ɛwɔ mogya ho abɛtɔ dwa.
Thiotepa

**Thiotepa** (INN ), edin a y3di de dwuma wc dwom 3y3 **Tepadina** 3ni nnea 3keka hwo , y3 de sa cancer yare3.  Thiotepa 3y3 organophosphorus compound a ni formula 3y3 (C2H4N)3PS.

## NSUNSWANSUC
Nsunswansuc a thiotepa de ba 3y3 side effect of thiotepa 3y3 bone marrow suppression a 3di leukopenia , thrombocytopenia 3ni anemia 3ba .

## BEBIA MMOA EFIRI
Theophylline

**Theophylline**, a wɔsan nso frɛ no 1,3-dimethylxanthine, ɛyɛ also known as **1,3-dimethylxanthine**, ɛyɛ aduro a phosphodiesterase ɛwɔ mu na esi adenosine ho kwan. Wɔde sa akoma yadeɛ ne ntehyeewa. Ne nnuro mfrafraeɛ mu no sɛ methylxanthine nnuro afoforɔ mu. ( nhwɛsoɔ., theobromine ne kafain a brɔfo kasa mu no wɔfrɛ no caffein).
Celecoxib/tramadol

Celecoxib/tramadol a wɔtɔn wɔ Seglentis din mu no, yɛ nduru ahodoɔ anoɔden a yɛakeka abom mu a ɛko tia yareɛ mmoawa ne opioid tramadol a wɔde ɛko tia ɛyaw.
Tetanus toxin

Tetanus toxin (TeNT) yɛ neurotoxin bi a ɛyɛ den yie a Clostridium tetani nkwammoaa a ɛwo no yɛ wɔ anaerobic tebea mu, na ɛde tetanus ba. Wonnim dwuma a Clostridia di wɔ asase mu baabi a wɔtaa hyia no. Wɔsan frɛ no spasmogenic toxin, tentoxilysin, tetanospasmin, anaa tetanus neurotoxin.

## Ne nkyekyɛmu

* Tetanus mmoawa no tumi nyini fa ntini mu kɔ ntini kɔ ntini foforɔ mu. Ɛtumi tene kɔ w'adwene ntini (CNS) ne  dyneins so kɔ akyire.

## Ne nhyehyɛeɛ
Tetanus awuduro no protin(protein) no mu duru yɛ bɛyɛ ɔha ne aduonum(150 kDa). Wɔkyerɛ ase firii tetX gene no mu sɛ protein baako a ɛno akyi no wɔpae mu mmienu: 100 kDa a emu yɛ duru anaa B-chain ne 50 kDa a emu yɛ hare anaa A-chain. Wɔde disulfide nkekamu na ɛka nkɔnsɔnkɔnsɔn no bom.
Tetracaine

**Tetracaine** a wɔsane frɛ no amethocaine yɛ aduro a wɔde di sɔ yaw ano na wɔde kum nnipadua akwaa bi te sɛ ani, hwene anaa menem. Wɔsane de fa honam ani berɛ a wɔde panneɛ rebɛwɔ obi no na ama yaw a ɛde ba no ano ba fam. Mpɛn pii no, wɔyɛ no nsuo de fa baabi a wɔbɛwɔ panneɛ no. Ne dwumadie no nsusuansoɔ tumi tena hɔ anibu aduasa (30) ne simma du nnum ntam (15) berɛ a wɔde afa ani ho no.
Terbinafine

**Terbafine** yɛ antifungal  aduro a ɔde yɛ pityriasis versicolor, fungal nail yareɛ ne ringworm a ɛka jock itch ne athlete's foot. Ɔnom fa y'anum anaa ɔde ka ka honam no te sɛ nkuun. Nkuun no deɛ ɔnfa nnyɛ fungal nail yareɛ no.
Anti-tetanus immunoglobulin

Anti-tetanus immunoglobulin, a wɔsan frɛ no tetanus immune globulin (TIG) ne tetanus antitoxin, yɛ aduro a wɔde nnuru a ɛko tia tetanus awuduro na ɛyɛ. Wɔde si tetanus ano wɔ wɔn a wɔwɔ kuro a asiane kɛseɛ wom, wɔmfa tetanus toxoid nhyɛ wɔn ho ban koraa, anaasɛ wɔwɔ HIV/AIDS no mu. Wɔde saa tetanus ka nnuro a ekum yareɛ mmoawa ne nnuro a ɛma ntini mu dwo. Wɔnam aduro a wɔde twitwi ntini bi mu so na ɛma. Wɔde aduro no fa bi gu baabi a kuro no wɔ.

Nneyɛɛ bɔne a ɛtaa ba ne ɛyaw a ɛba baabi a wɔde twitwi no ne atiridii. Ebia akisikuro a anaphylaxis ka ho ntaa mma. Asiane nso sua koraa sɛ yadeɛ te sɛ yare mmoawa a ɛma mmerɛboɔ mu yare ne HIV/AIDS bɛtrɛ wɔ nnipa de no mu. Sɛ wɔde di dwuma berɛ a wɔyem ne berɛ a wɔrema nufo no yɛ deɛ wogye tom. Wɔde onipa anaa apɔnkɔ mogya mu nsu na ɛyɛ.
Tenofovir disoproxil

Tenofovir disoproxil a wɔtɔn no wɔ din Viread ne afoforɔ ase no yɛ aduro a wɔde sa hepatitis B a yɛntumi nsa na wɔsane de si HIV/AIDS ano. Mpɛn pii no wɔkamfo sɛ wɔmfa nni dwuma wɔ nnuro afoforɔ a ɛkum ɔyare mmoawa ho.
Terazosin

Terazosin, a Hytrin ne nnwumakuo ahodoɔ binom na ɛtɔn no,yɛ aduro a wɔde sa dwonsɔtwaa ne mogyaborosoɔ ho mpopoeɛ.Sɛ ɛyɛ mogyaborosoɔ a, ɛntumi nsa no yie.

## Sintɛsis
Piperazine ho adwuma ne 2-furoyl chloride a catalytic hydrogenation de 2 ba.

## Nhwehwɛmu
Nhwehwɛmu a wɔyɛɛ no 2022 kyerɛɛ sɛ terazosin tumi de adwenem banbɔ wɔ adwene no mu ba

## Beaeɛ A Menyaa Mmoa Firiiɛ
Teriparatide

**Teriparatide din a wɔde nim no wɔ nnuro adwasuo ne**  **Forteo. Ɛka** parathyroid hormone nkorabata no ho. Ɛboa ma nnompe toa. Sɛ ebia, a obi nnumompe mu bu a, ɛboa tumi toa.  Wɔde sa  osteoporosis.  Ne su ne  34 N-terminal amino acids a yɛnya wɔ 84-amino acid mu no sesɛ. 

## Beaeɛ a Menyaa Mmoa Firiiɛ
Emtricitabine/rilpivirine/tenofovir

**Emtricitabine/rilpivirine/tenofovir**, a wɔtɔn wɔ din **Complera** mu no yɛ nnuru a wɔde di HIV/AIDS ho dwuma. Gilead Sciences ne Johnson & Johnson's Tibotec na wɔyɛɛ aduru no, na US Food and Drug Administration (FDA) penee so wɔ August 2011, na European Medicines Agency nso penee so wɔ November 2011, maa ayarefo a wonnyaa HIV ho ayaresa da. Wonya no te sɛ kuruwa biako a wotwa no da biara.

## Nnuruyɛ dwumadie
Wɔde emtricitabine/rilpivirine/tenofovir di dwuma de sa HIV- 1 yareɛ wɔ mpanimfoɔ a wonnii HIV- 1 nnuru da (berɛ a yareɛ mmoawa no antumi annye nnuro a ɛko tia HIV- 1 yi ano) na wonni HIV- 1 RNA a ɛboro 100,000 wɔ mL biara mu wɔ wɔn mogya mu ( "viral load")

## Baabi a menyaa mmoa firiiɛ
Dolutegravir/lamivudine/tenofovir

Dolutegravir(DTG),a Tivicay adwumakuo na wɔtɔn, yɛ aduro a wɔde sa HIV anaa sɛ babasowerɛmfoɔ.Wɔtumi nso de si HIV ano.Wɔde fa anomu.

## Yareɛ a Ɛsa
Wɔagye dolutegravir ato mu a wɔde yɛ adwuma wɔ nnipa dodoɔ a wɔwɔ HIV. Wɔtumi de sa mpaninfoɔ a wɔwɔ HIV a  wɔnyaa HIV ho ayarehwɛ biara.

## Nsunsuansoɔ
Dolutegravir ho nsunsuansoɔ pa ara ne sɛ wontumi nna ne tipaeɛ.Nsunsuansoɔ nso a ano yɛ den ne brɛboɔ a ɛntumi nni dwuma papa.

## Abakɔsɛm
Wɔ Ɔgyefoɔ bosome afe 2013 mu no,wɔ U.S nnuane ne nnuro dwumakuo no,wɔde too dwa sɛ dolutegravir ho nyetomu no bɛkyɛ.

## Akwanya
Wɔ Oforisuo bosome afe 2024 no,Colombia aban gye too mu sɛ dolutegravir na wɔde bɛdi dwuma.

## Beaeɛ A Menyaa Mmoa Firiiɛ
Tetanus vaccine

**Tetanus vaccine**, a wɔsan nso frɛ no tetanus toxoid (TT), ɛyɛ toxoid vaccine a wɔde si tetanus kwan.  Wɔkamfo tetanus nnuro nnum wɔ mmɔfra berɛ mu ɛka nsia no ho wɔ mmabunu berɛ mu. Sɛ wɔ wɔ tetanus mmiensa wie a, ɛkame ayɛsɛ, obiara awɔ ahyɛaseɛ, nanso wɔwɔ nnuro nkaeɛ no mfie du ntam boa bɔ nkwammoa ho ban.
Lamivudine/tenofovir

**Lamivudine/tenofovir disoprosil** a watɔn wɔ Simduo din ase ne nkeka ho, a ɛyɛ aduro a wakabom antiretroviral nnuro ma HIV/AIDS ma nkwadaa ne mpanin a ɔmo mu duru yɛ 35 kilogram. Ɛkura lamivudine ne tenofovir disaproɔil. Ɔnom fa wanum.
Elvitegravir/cobicistat/emtricitabine/tenofovir

**Elvitegravir/cobicistat/emtricitabine/tenofovir**, aduro a wɔde ɛdin ***Stribild*** na ɛtɔn a wɔsane frɛ no ***Quad pill***, yɛ aduro a wɔaka nnuro ahodoɔ bi abom a yɛ no baako. Saa aduro yi, wɔde sa Babasowerɛmfoɔ *(HIV/AIDS).* Elvitegravir, emtricitabine ne tenofovir disoproxil boa te yareɛ ahoɔden so na cobicistat no boa ma aduro no yɛ adwuma yie denam te a ɛte ɛnzyme ahodoɔ a berɛboɔ ne yafunu no de ba no na ɛdane elvitegravir aduro ahoɔden ma nnipadua no. Wɔnom fa ano no mu. Gilead Sciences na ɛyɛɛ saa aduro yi.
Ringer's lactate solution

Rimger’s lactate solution (RL),a wɔsan frɛ no sodium lactate solution ,lactated Ringer's ,ne Hartmanns solution ,yɛ nnuro ahodoɔ binom a wɔaka abom na wɔde nsuo afra.

## Yareɛ A Wɔde Sa
Wɔtaa de ringer's lactate solution sa nsuo a ɛnni nipadua no mu sɛ mogya we firi nipadua no mu a, ɛsiane ɔhaw bi anaa sɛ sɛɛgyiri bi.

## Abakɔsɛm
Sydney Ringer na ɔde ringer's lactate solution baeɛ wɔ 1880 mu.Ringer suaa apɔnkyerɛnne bi akoma a wɔayi ato hɔ.

## Mmoa A Wɔde Sa
Wɔde hwɛ sawa wɔ mmoa nketewa mu.Wɔtumi de nsuo no fa ne mu anaa sɛ wɔde gu ne ho.

## Beaeɛ A Menyaa Mmoa Firiiɛ
Rifaximin

Rifaximin, yɛ aduro a wɔde hwɛ akwantufoɔ a  wɔn yam tu. Ɛgyina rifamycin antibayotese abusuakuo no so bi.Ɛfiri berɛ a wɔgye too mu  wɔ Italy afe 1987 mu no,aman bɛboro aduasa nso agye ato mu a wɔde sa nyarewa ahodoɔ bi te sɛ irritable bowel syndrome ne hepatic encephalopathy.

## Yareɛ A Wɔde Hwɛ

### Akwantufoɔ a wɔn Yam tu
Wɔde Rifaximin hwɛ akwantufoɔ a wɔn tu a E.Coli mmoawa a ɛwɔ mpaninfoɔ ne mmɔfra a wɔadi mfeɛ dummienu mu no.Mmoawa a ɛma  akwantufoɔ yam tu no, rifaximin na ɛsi saa mmoawa no kwan mma wɔn nyini.

## Nsɔano Soronko
Wɔn a wɔn yam tu no,ɛwɔ sɛ wɔgyae rifaximin fa sɛ wɔwɔ nyarewa bi te sɛ rifabutin, rifampin, ne rifapentine. Ɛbɛtumi ama nnuro bi a ɛwɔ nipadua no mu agyae nadwuma yɛ(ɛbi te sɛ tafɔdo nnuro).

## Nsunsuansoɔ
Rifaximin wɔ din a ɛkyerɛ sɛ ɛho nni asɛm biara ɛsiane wɔnfa no ntoatoasoɔ nti.Nhwehwɛmu a wɔyɛɛ no asupiti ankyerɛ sɛ rifaximin wɔ nsunsuansoɔ bi.Wɔanhunu owuo biara berɛ a wɔde aduro no dii dwuma no.

## Beaeɛ A Ɛwɔ
Wɔ United States no,Salix nnuro dwumakuo na wɔtɔn rifaximin pa ara a ɛdin a wɔde tɔn ne Xifaxan.

## Beaeɛ A Menyaa Mmoa Firiiɛ
Balkan Ko a Edi Kan

**Balkan Ko a Edi Kan** (October 8, 1912 – March 30, 1913) yɛ ɔko a ɛkɔɔ so wɔ Balkan Apam (a Serbia, Greece, Montenegro ne Bulgaria ka ho) ne Ottoman Ahemman no ntam. Na Balkan aman nkabom no korɔn sen Ottoman asraafo a na wɔn dodow ne ɔkwan a wɔfa so yɛ adwuma no sua, enti wodii nkonim ntɛmntɛm.

Balkan Apam no nkonimdi no kyerɛe sɛ mfeha anum baa awiei Ottoman nniso a ɛwɔ Balkan supɔw no so. Ottomanfo hweree wɔn nsasesin nyinaa wɔ Europa, gye asase ketewaa bi a ɛwɔ Marmara Po no atifi fam mpoano ne Constantinople . Tharce ne Makedonia Apuei fam fa kɛse no ara faa Bulgaria asasesin no. Serbia dii Kosovo, Makedonia atifi fam atɔe mmeae no so nkonim . Greece faa Eripus, nsupɔw a ɛwɔ Aegean Po no mu ne Macedonia anafo fam atɔe wɔ Thessaloniki na bere a wɔde wɔn nsa hyɛɛ London Apam ase akyi no, ɛma wɔhyehyɛɛ Albania man a ɛde ne ho. Nanso, akasakasa a ɛkɔɔ so wɔ Makedonia mu mpaapaemu ho no maa mpaapaemu baa nkabom no mu, na Balkan Ko a Ɛto so Abien no fii ase wɔ asram kakraa bi akyi.
Rifampicin

Rifampicin,a wɔsan frɛ no rifampin,yɛ ansamycin antibayotese a wɔde hwɛ nyarewa ahodoɔ bebree,a ɛbi ne nsamanwa(TB), Mycobacterium aviumcomplex,kwata,ne Legionniares yareɛ ahodoɔ nyinaa.

## Yareɛ A Wɔde Sa

### Mycobacteria
Wɔde rifampicin sa nsamanwa ne antibayotese binom te sɛ, pyrazinamide, isoniazid, ne ethambutol.Sɛ wɔde resa nsamanwa a,wɔyɛ no dabiara.

## Nsunsuansoɔ
Ɛho nsunsuansoɔ a ano yɛ den pa ara ne hɛpatɔtɔsiticiti(hepatotoxicity),na nnipa a wɔnya no wɔtaa yɛ wɔn brɛboɔ ho nhwehwɛmu hwɛ sɛ wɔn brɛboɔ ho ato kyema anaa.

## Sɛdeɛ Ɛteɛ
Rifampicin yɛ pɔlekitide(polyketide) a ɛka nnuro binom a wɔfrɛ no ansamycins ho,a wɔato no din saa esiane sɛdeɛ ɛteɛ na ɛwɔ naftɔkinɔne(naphthoquinone)no nti.

## Nkitahodie
Rifampicin yɛ aduro a ano yɛ den pa ara wɔ hɛpatik sytɔkrom(cytochrome)abusuakuo no mu a ɛbi ne: CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP3A4, CYP3A5, ne CYP3A7.Ɛma nnuro binom yɛ adwuma ntɛm na ɛba no saa a,ɛnam sɛdeɛ aduro no ahyehyɛ so ma nahoɔden  kɔ fam.

## Abakɔsɛm
Wɔ 1957 mu no,wɔsaa anwea kakra firii pine kwaeɛ a ɛwɔ Frɛnch nsutene no mu de yɛɛ nhwehwɛmu de kɔɔ Lepetit nnurokuo nhwehwɛmu a ɛwɔ Milan,Italy. Ɛhɔ no,nhwehwɛmukuo bi a Piero Sensi ne Maria Teresa Timbal da wɔn ano no nyaa bacterium foforɔ.Saa afifideɛ yi de nneɛma foforɔ bi baeɛ ne antibayotese nnwuma bi.

## Asetena ne Amammerɛ

### Kokoram farebae nkekaeɛ
Wɔ Ɔsanaa bosome mu 2020 no,ɛyɛ U.S nnuane ne nnurokuo(FDA) bɛhunuu nitrosamine nkekaeɛ wɔ rifampin binom mu.

## Beaeɛ A Menyaa Mmoa Firiiɛ
Rifampicin/isoniazid/pyrazinamide

## <small>Rifampicin/isoniazid/pyrazinamide,a wɔsan frɛ no rifampon/isoniazid/pyrazinamide,a ɛnam Rifater so na wɔtɔn no,yɛ aduro a wɔde  hwɛ  nsamanwa. Ɛyɛ aduro a wɔaka rifampicin, isoniazid, ne pyrazinamide abom.Wɔtumi de ɛno nko ara sa yareɛ anaa sɛ wɔde nnuro binom a ɛtumi nsamanwa ka ko.Wɔde fa anomu.</small>

## Yareɛ A Wɔde Sa
Anidasoɔ a ɛwom sɛ wɔaka nnuro yi abom ne sɛ nnipa bɛkɔ so anom nnuro mmiɛnsa no nyinaa. Bio,sɛ nnipa werɛ fi sɛ wɔbɛnom aduro no mu baako anaa mmienu a,wɔrentumi nya aduro no nkaeɛ no mu ahoɔden.

## Asetena Ne Amammerɛ
Aventis na wɔyɛeɛ

## Hwɛ Nso
* Nsamanwa ayarehwɛ
* Rifampicin + isoniazid + ethambutol 

## Beaeɛ A Menyaa Mmoa Firiiɛ
Sumatriptan/naproxen

Sumatriptan a wɔtɔn no hyɛ edin Imitrex ase ne afoforɔ, ɛyɛ aduru a wɔde sa atiridiinini ne ti yaa a ɛyɛ akuwakuw. Yɛde gu yɛn anum na ɛfa, wɔde fa anom, anaasɛ wɔde gu honam ani. Mpɛn pii no, yareɛ no ho nsunsuansoɔ da adi wɔ nnɔnhwere mmiɛnsa ntam.

## Dwuma a aduru no tumi yɛ
Sumatriptan tumi boa ma atiridiinini ne ti yaa a ɛyɛ akuwakuw a ɛyɛ den no tumi gyae anaasɛ ɛtumi ba fam. Sɛ wote yaa no na sɛ wonom no ntɛm a ɛtumi di dwuma yie. Sumatriptan a wɔde twitwi nipadua no tu mpɔn sene nnuru afoforɔ. Wobetumi de sumatriptan a wɔnom nso adi dwuma sɛ woti yɛ wo ya kɛseɛ a.
Ethambutol

**Ethambutol** ( **EMB**, **E** ) yɛ aduro a wɔde sa nsamanwaw.Wɔtaa de nsamanwa nnuro binom ka ho na ɛsa, ɛbi te sɛ isoniazid, rifampicin ne pyrazinamide.Wɔtumi nso de hwɛ Mycobacterium aviumcomplex, ne Mycobacterium kanasii. Wɔde fa anomu.

## Yareɛ A Wɔde Sa
Wɔde nnuro ahodoɔ ka Ethambutol ho hwɛ nyarewa ahodoɔ bi te sɛ: nsamanwa, Mycobacterium avium complex, ne Mycobacterium kansasii.

## Nsunsuansoɔ
* Optic neuritis (mmɔfra a wɔnyaa mfeɛ nsia na wɔnya)
* Red–green color blindness Ɛwɔ sɛ wɔn a wɔnom ethambutol no, wɔma wɔn ani kɔ wɔn ho na wɔhwɛ wɔn ani ne wɔn wedeɛ.
* Arthralgia
* Hyperuricaemia
* Vertical nystagmus
* Ahoɔhene

## Hwɛ Nso
* Chiral drugs
* Chirality
* Enantiopure drug
* Stereochemistry

## Beaeɛ A Menyaa Mmoa Firiiɛ
Rituximab

Rituximab a,ɛyɛ adwumakuo Rituxan ne nnwumakuo ahodoɔ binom na wɔtɔn no,yɛ aduro a wɔde hwɛ nyarewa ahodoɔ bi ne kokoram yareɛ ahodoɔ binom.

## Yareɛ A Wɔde Sa
Rituximab yɛ nnuro a wɔde ko tia CD20, a ɛwɔ B cells honam ani.Ɛyɛ adwuma sɛdeɛ ɛpepa  B cells wedeɛ no ani no a ɛma plasma  cells hematopoietic stem cells no a ɛnkyerɛ CD20 no.

## Nsunsuansoɔ
Ɛho nsunsuansoɔ a ano yɛ den no tumi de owuo ba.

## Abakɔsɛm
IDEC nnuro adwumakuo a ɛhyɛ IDEC C2B8 na wɔyɛɛ Rituximab. US man a wɔyɛɛ aduro no de too dwa 1998 na ɛwuu wɔ 2015

## Asetena Ne Amammerɛ

### Ekɔnɔmiks
Wɔ 2014, Genentech sane hyehyɛɛ Rituxan sɛ aduro soronko, adurokuo a na ɛwɔ US,wɔn   a wɔtɔn nnuro nko ara.Ɛfiri sɛ wɔn a wɔfa no atufoɔboɔ no rentua sika biara,na mmom asupiti na wɔbɛtua.

## Nhwehwɛmu

### Myalgic encephalomyelitis/chronic fatigue syndrome
Wɔ 2009,ayarefoɔ a wɔgye methotrexate B-cell no hunuu encephalomyelitis anaa sɛ koankorɔ(ME/CFS)ho mpopeɛ.

## Beaeɛ A Menyaa Mmoa Firiiɛ
Naloxone

Naloxone yɛ opioid a ɛko tia: aduro a wɔde dane anaasɛ ɛte opioid nkɛntɛnso soɔ. Ne nhwɛsoɔ no bi ne sɛ, wɔde di dwuma de san home bio wɔ opioid a wɔnom boro so akyi. Nkɛntɛnso no firi aseɛ wɔ simma mmienu mu berɛ a wɔde fa ntini mu, simma nnum berɛ a wɔde gu ntini mu, ne simma du sɛ aduro a wɔde petepete hwene mu. Naloxone si opioids nsunsuansoɔ ano simma 30 kɔsi aduokron.

Sɛ wɔde ma nnipa a wɔde wɔn ho to opioid so a, ɛbɛtumi ama wɔanya opioid a wɔgyae ho sɛnkyerɛnne, a deɛ ɛka ho ne ahomegyeɛ, basabasayɛ, akisikuro, ɛfeɛ, akoma a ɛbɔ ntɛmntɛm, ne fifire. Sɛdeɛ ɛbɛyɛ na wɔasi wei ano no, wobetumi de nnuro nketenkete ama simma kakraa biara kosi sɛ wobenya deɛ wopɛ. Wɔ wɔn a wɔadi kan anya akomayareɛ anaasɛ wɔnom nnuro a ɛka akoma no wɔ kwan a enyɛ so no, akomayareɛ foforɔ aba. Ɛte sɛ deɛ asiane biara nni ho wɔ nyinsɛn mu, berɛ a wɔde ama mmea kakraa bi akyi. Naloxone yɛ opioid receptor antagonist a ɛnyɛ deɛ wɔpaw na ɛyɛ akansie. Ɛyɛ adwuma denam adwenemhaw a ɛba ntini a ɛwɔ mfinimfini ne home nhyehyeɛ mu a opioids de ba no so.

Wɔmaa Naloxone tumi krataa wɔ afe 1961 mu na wɔpenee so sɛ wɔmfa opioid nni dwuma ɛboro so wɔ United States wɔ afe 1971. Ɛwɔ Wiase Nyinaa Akwahosan Ahyehyɛdeɛ no Nnuro a Ɛho hia Nkyerɛdeɛ mu.
Mometasone

**Mometasone**, a wɔsan frɛ no mometasone y 3 s, yɛ steroid (titiriw, glucocorticoid) aduro a wɔde sa honam ani tebea hordoɔ bi,  atiridii, ne ayamtuo. Titiriw no wɔde si ayamtu ntua ano sen sɛ wɔbɛsa.Wobetumi de apete honam ani, ahome, anaa wɔde adi dwuma wɔ hwene mu. Wɔde mometasone furoate, ɛnyɛ mometasone, di dwuma wɔ nnuroyɛ mu.

Nneyɛe bɔne a ɛtaa ba berɛ a wɔde di dwuma ma ayamtu no bi ne ayamtu ne akisikuro. Enti wɔkamfo kyerɛ sɛ wɔhohoro ano berɛ a wɔde adi dwuma awie no. Sɛ wɔde di dwuma berɛ tenten a, ebetumi ama asiane a ɛwɔ hɔ sɛ wobenya atiridiinini ne atiridiinini no ayɛ kɛseɛ. Nneɛma bɔne a ɛtaa ba berɛ a wɔde di dwuma wɔ hwene mu no bi ne home akwaa a ɛwɔ soro ne mogya a ɛba hwene mu. Nneɛma bɔne a ɛtaa ba berɛ a wɔde gu honam ani no bi ne akisikuro, honam ani a ɛyɛ mmerɛ, ne ɛyaw. Ɛyɛ adwuma denam ɛfe a ɛte so.

Wɔmaa Mometasone furoate tumi krataa wɔ afe 1981 mu na wɔde dii dwuma wɔ aduroyɛ mu wɔ afe 1987 mu. Ɛwɔ Wiase Akwahosan Ahyehyɛdeɛ no Nnuro a Ɛho Hia mu na wobetumi anya sɛ aduro a wɔde yɛ nnuro a wɔde yɛ nnuro a wɔde di dwuma wɔ ɔkwan a ɛfata so. Wɔ afe 2021 mu no, na ɛyɛ nnuro a ɛto so 266 a wɔtaa kyerɛ ma wɔ United States, na wɔkyerɛ bɛboro ɔpepem 1.
Acetylcysteine

Acetylcysteine ​​a wɔsan frɛ no N-acetylcysteine ​​(NAC), a ɛnsɛ sɛ wɔde frafra N-acetylcarnosine a wɔsan frɛ no tiawa sɛ ‘NAC’ no yɛ aduru a wɔde sa paracetamol a wɔnom boro so na wɔde ma nsuo a ɛyɛ den a ɛwɔ ankorankorɛ a wɔwɔ ahurututu mu yadeɛ a enni sabea mu no yɛ mmerɛ te sɛ ahurututu mu yadeɛ ne ahurututu mu yadeɛ. Wɔde adi dwuma de asa lactobezoar a ɛwɔ nkokoaa mu. Wobetumi de ahyɛ ntini mu, wɔde ano, anaasɛ wɔahome sɛ nsuyiri. Nnipa binom de di dwuma sɛ aduannuro.

Nneɛma bɔne a ɛtaa ba ne akisikuro ne ɛfeɛ berɛ a wɔde ano nom. Ɛtɔ mmere bi a, honam ani betumi ayɛ kɔkɔɔ na ayɛ mmerɛ wɔ kwan biara a wɔfa so de ma no so. Anaphylaxis a ɛnyɛ nipadua no mu tumi a ɛko tia nyarewa nso betumi aba. Ɛte sɛ deɛ asiane biara nni ho wɔ nyinsɛn mu. Sɛ wɔde paracetamol di dwuma boro so a, ɛyɛ adwuma denam glutathione dodoɔ a ɛkɔ soro, aduro a ɛko tia yadeɛ mmoawa a ebetumi asi awuduro a ɛpaapae paracetamol mu no ano. Sɛ wɔhome a, ɛyɛ adwuma sɛ mucolytic denam mucus no mu duru a ɛso te so.

Acetylcysteine ​​no, mfiriaseɛ no wɔmaa no tumi krataa wɔ afe 1960 mu na wɔde dii dwuma wɔ aduroyɛ mu wɔ afe 1968 mu. Ɛwɔ Wiase Akwahosan Ahyehyɛdeɛ no Nnuro a Ɛho Hia a Wɔahyehyɛ no mu. Ɛwɔ hɔ sɛ aduro a wɔde yɛ nnuro.

Amino acid a sulfur womu a wɔfrɛ no cysteine ​​ne methionine no yɛ mmerɛ sɛ oxidized sen amino acid afofro no.
Mycophenolic acid

Mycophenolic acid yɛ aduro a ɛma nipadua no tumi ko tia nyarewa a wɔde si po a wɔpo wɔ akwaa a wɔde ma akyi no ano na wɔde sa tebea hodoɔ a nipadua no tumi ko tia nyarewa te sɛ Crohn yadeɛ ne lupus.Titiriw no wɔde di dwuma wɔ asaabo, akoma, ne mmerɛboɔ a wɔde ma akyi. Wobetumi de ano anaa wɔde ahyɛ ntini bi mu ama. Ɛba sɛ mycophenolate sodium ne mycophenolate mofetil.

Nneɛma bɔne a ɛtaa ba ne akisikuro, yadeɛ mmoawa, ne akisikuro. Nsunsuansoɔ fofrɔ a ɛyɛ hu ne kokoram ho asiane a ɛkɔ soro, multifocal leukoencephalopathy a ɛkɔ so, mogya a ɛtɔ kɔ nipadua mu, ne mogya a ɛtɔ wɔ yafunu mu. Sɛ wɔde di dwuma berɛ a wɔyem a, ebetumi apira akokoaa no. Ɛyɛ adwuma denam inosine monophosphate dehydrogenase (IMPDH) a esi ano, a lymphocytes hia na ama wɔayɛ guanosine.

Mycophenolic acid na Italiani Bartolomeo Gosio hunuu no mfiriaseɛ no wɔ afe 1893 mu. Wɔsan hunuu no wɔ afe 1945 ne 1968 mu. Wɔpenee so sɛ wɔmfa nni dwuma wɔ aduroyɛ mu wɔ United States wɔ afe 1995 mu berɛ a wohunuu ne tumi a ɛma nipadua no tumi ko tia nyarewa wɔ 1990 mfeɛ no mu akyi. Wobetumi anya bi sɛ aduro a wɔde yɛ nnuro a wɔde di dwuma wɔ ɔkwan a ɛfata so. Wɔ afe 2020 mu no, na ɛyɛ nnuro a ɛto so 313 a wɔtaa kyerɛ ma wɔ United States, na wɔkyerɛ bɛboro mpem 900.
Ethambutol/isoniazid/pyrazinamide/rifampicin

Ethambutol/isoniazid/pyrazinamide/rifampicin, a wɔsan frɛ no   ethambutol/isoniazid/pyrazinamide/rifampin,yɛ aduro a wɔde sa nsamanwa.Ɛyɛ aduro a wɔaka ethambutol, isoniazid, pyrazinamide, ne rifampicin abom.Wɔtumi de ɛno nko ara sa yareɛ anaa sɛ wɔde aduro a ɛtumi sa nsamanwa ka ho.Wɔde fa anomu.Ɛho nsunsuansoɔ ne nnuro a ɛka ho no.Wɔtumi de pyridoxine te ahoɔmmerɛ so.Ɛnyɛ mma nnipa a wɔwɔ brɛboɔ ho haw anaa sɛ sawa ho haw.Ɛnyɛ mma mmɔfra nso.Sɛ wonyinsɛn na wonom a,worenhunu no yie.Sɛ wokɔ wiase nyinaa apɔmuden kuo no mu a,ɛka nnuro a ɛhia pa ara no ho bi.Voractiv ne Rimstar a ɛwɔ Uk na wɔtɔn.

## Beaeɛ A Menyaa Mmoa Firiiɛ
Ethambutol/isoniazid/rifampicin

Ethambutol/isoniazid/rifampicin, a wɔsan frɛ no ethambutol/isoniazid/rifampin, yɛ aduro a wɔaka abom a wɔde sa nsamanwa.Nnuro a ɛwom ne ethambutol, isoniazid, ne rifampicin.Wɔtumi de ɛno nko ara anaa sɛ nnuro binom a ɛtumi sa nsamanwa di dwuma.Wɔde fa anomu.Ɛho nsunsuansoɔ ne nnuro a ɛkeka ho no.Ɛnyɛ mma mmɔfra.

## Hwɛ  Nso

* Ethambutol/isoniazid/pyrazinamide/rifampicin

## Beaeɛ A Menyaa Mmoa Firiiɛ
Ethambutol/isoniazid

Ethambutol/isoniazid a nnuro a wɔaka abom a wɔde sa nsamanwa.Ethambutol ne isoniazid na wɔaka abom de ayɛ saa aduro no.Wɔde ka nnuro binom a ɛtumi sa nsamanwa ho.Wɔde fa anomu.

Ɛho nsunsuansoɔ ne nnuro a ɛkeka ho no.Nsunsuansoɔ no bi ne sɛ nipadua no ntumi nka mmɔ mu nyɛ adwuma yie,ahoɔmmerɛ, ne brɛboɔ ho haw. Brɛboɔ ho haw no bɛtumi ayɛ kɛse wɔ wɔn a wɔanya mfeɛ bɛboro aduonum no.Ɛnyɛ mma mmɔfra.Sɛ wonyinsɛn na wo nom a wonhunu nadwuma yie.

Wɔyi firii wiase apɔmuden kuo no so sɛ ɛnyɛ aduro a ɛho hia wɔ afe 2019 mu.Worenya saa nnuro yi bi wɔ Canada anaa sɛ United States.

## Beaeɛ A Menyaa Mmoa Firiiɛ
Buprenorphine/naloxone

Buprenorphine/naloxone, a woato ne din Suboxone  yɛ aduro a wɔde ka bom a woahyɛ da ayɛ a buprenorphine ne naloxone ka ho. Wɔde sa opioid a wɔde di dwuma ho haw, na ɛte opioid a wɔde di dwuma ho haw a wowuwu so 50% (denam asiane a ɛwɔ hɔ sɛ wɔbɛnom aboro so wɔ opioid a ɛyɛ agonist a edi mu te sɛ heroin anaa fentanyl so). Ɛma akɔnnɔ a ɛwɔ obi mu sɛ ɔde bedi dwuma ne sɛnkyerɛnne a ɛkyerɛ sɛ ɔtwe ne ho firi ho no firi hɔ. Buprenorphine/naloxone wɔ hɔ a wɔde di dwuma wɔ akwan ahodoɔ mmienu so, tɛkrɛma ase anaa anim.

Nneyɛɛ bɔne betumi ayɛ home mu adwenemuhaw (home a ɛso te), aniwa nketenkete, nna, ne mogya mmorosoɔ a ɛba fam. Asiane a ɛwɔ buprenorphine/naloxone a wɔde di dwuma boro so mu (gye sɛ wɔde nnuro afofrɔ a ɛma obi dwo ka ho) no sua dodo, na ɛba fam sen methadone, nanso ɛda adi sɛ nkurɔfoɔ begyae buprenorphine/naloxone ayaresa sen methadone. Buprenorphine (te sɛ methadone) yɛ ayaresa a wɔfa wɔ nyinsɛn mu.

Wɔ dodoɔ a ɛba fam mu no, buprenorphine de opioid nkɛntɛnsoɔ a wɔtaa nya no ba; dodo a ɛkɔ soro a ɛboro dodoɔ bi so no mma ennya nkɛntɛnsoɔ kɛseɛ. Wogye di sɛ wei ma asiane a ɛwɔ hɔ sɛ wɔbɛnom aboro so no so te sen opioid afofrɔ bi. Naloxone yɛ opioid a ɛko tia a ɛne opioid afofrɔ (a buprenorphine ka ho) di kan na sɛ wɔde injection ma. Naloxone ntumi nkɔ nipadua no mu yie berɛ a wɔfa ano no na wɔde ka ho de te asiane a ɛwɔ hɔ sɛ nkurɔfoɔ de aduro no bedi dwuma kwammɔne so denam paneɛ wɔ so. Wɔde nnuro a wɔde twitwi nipadua no mu anaasɛ wɔde di dwuma kwammɔne so wɔ hwene mu no da so ara kɔ so, na nnansa yi ara wɔde naloxone a wɔde di dwuma kwammɔne so a wɔde twitwi nipadua mu no asi ano no ho kyim na ahosiesie a naloxone ka ho no betumi mpo ayɛ nea ahobammɔ wom kɛseɛ sen nnuro a buprenorphine nkutoo wom. Ɛte sɛ deɛ dodoɔ a wɔde di dwuma kwammɔne so wɔ U.S. no sua sen opioid afofrɔ.

Wɔpenee nnuro a woaka abomu no so sɛ wɔmfa nni dwuma wɔ aduroyɛ mu wɔ U.S. wɔ afe 2002, ne Europa Aman Nkabom wɔ afe 2017 mu . Wɔpenee generic version so wɔ US wɔ afe 2018 mu. Wɔ afe 2019 mu no, na ɛyɛ nnuro a ɛto so 272 a wɔtaa kyerɛ ma wɔ U.S., na wɔkyerɛ bɛboro ɔpepem 1.