Caffeine

**Caffeine** is a central nervous system (CNS) stimulant drug. It is found in parts of plants, for example tea leaves and coffee beans. Its artificial form is also used in some soft drinks and energy drinks. It is the world's most popular psychoactive drug, and is legal in all of the world, and is most often taken in a drink. 

## Sources 
Caffeine is naturally found in the fruits, leaves and beans of coffee, cacao, guarana and tea plants. 

The plants use caffeine as a *pesticide*. This is a chemical that kills insects if they eat the plant. It is the way the plant protects itself.

Caffeine was first extracted from cocoa beans into its purest form which is a white powder and the word originated from the German word “Kaffee” and the French word “café” which both mean caffeine.

When it comes from the guarana plant it is called **guaranine,** when it comes from a tea plant, it is called **theine,** and in the mate drink it is called **mateine** (this drink is an infusion made with Yerba mate).

## What caffeine is 
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Caffeine is a *stimulant* drug. A stimulant is a drug that increases body actions like heart rate, blood pressure, and metabolism. It makes a person more awake and alert.

Caffeine also is a diuretic. This means it makes a person make more urine (the waste liquid a person makes).

The caffeine chemical is called a *xanthine alkaloid*. This is a group of chemicals that are stimulants. Some xanthine alkaloids (like theophylline) are used to help asthma.

## What caffeine is used for 
The biggest use of caffeine is as a stimulant. People drink coffee and other drinks with caffeine to stay awake.

In the beginning caffeine was found to relieve hunger, so it was used for weight loss. That did not last because people were using too much. Caffeine can be dangerous when not used in the right way.

Doctors sometimes use caffeine as a medicine. It is added to analgesics (drugs used for pain). The short-term risk of this treatment seems to be that the babies treated gain less weight than usual. Caffeine is sometimes given to people after a lumbar puncture. This is when a needle is pushed between the bones of the lower back, normally to check for illnesses

## Problems with caffeine 
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The largest problem with caffeine is addiction. This is when people get bad symptoms when they do not have the drug. When people have *withdrawal* (feel bad because they do not have the drug) they drink more. This makes them feel better. But if they cannot get more, they are likely to feel some of the symptoms listed below:
* Headaches
* Being tired or need to sleep
* Caffeine can prevent sleep and in the long-term alters brain functions
** Sleep deprivation leads to a weakened connectivity between the amygdala and medial prefrontal cortex which regulate mood and emotion.
*** This causes the consumer to feel irritable, tired, restlessness, and anxious.
* Nausea (feeling like vomiting)

Caffeine can also hurt people if they drink a lot at once. If a person consumed 10-13 grams of caffeine quickly, between 80 and 100 cups of coffee, they would overdose and may even die. Caffeine overdose is a medical diagnosis. It is called: *Caffeine-Induced Organic Mental Disorder* or *Caffeine Intoxication*. People with this can have these symptoms:
* Very bad feelings like:
** *Paranoia* (feeling as if people are about to hurt the person)
** *Restlessness* or *nervousness* (with the person feeling like he cannot sit down or rest)
** *Anxiety* (very bad worry)
* Muscle movements that cannot be stopped
* Very fast heart rate
* Abnormal heart rhythms (even heart stopping)
* Very high blood pressure
* Vomiting
* Confusion (not knowing who the person is or where they are)

## Caffeine helps for 
Caffeine also has some strong advantages:
* Lower risk of coronary disease
* Cut stroke risk
* Speed up metabolism
* Increases memory
* Helps ward off Alzheimer’s
* Reduces kidney stone risk

## How much caffeine is safe 
250–300&nbsp;mg of caffeine a day is a *moderate* amount. That is as much caffeine that is in three cups of coffee (8oz each cup). More than 750–1000&nbsp;mg a day is a significant amount, but is very unlikely to kill someone. The Lethal Dose 50 of caffeine is 192&nbsp;mg per kilogram, in rats. In humans, it is between 150 and 200&nbsp;mg per kilogram (70-90 per pound.)

Caffeine is in many drinks and foods. This is *approximate* amounts of caffeine in some food and drink:

* Brewed coffee – 40 to 220&nbsp;mg in a cup
* Instant coffee – 30 to 120&nbsp;mg in a cup
* *Decaffeinated* coffee (with most caffeine taken out) – 3 to 5&nbsp;mg in a cup
* Tea – 20 to 110&nbsp;mg in a cup
* Soda drinks with caffeine – 36 to 90&nbsp;mg in 12 ounces. Some people think that soft drinks which are light in color do not contain caffeine. This is not always true.
* Milk chocolate – 3 to 6&nbsp;mg in an ounce
* Bittersweet chocolate – 25&nbsp;mg in an ounce

One ounce – abbreviated oz – is 30&nbsp;ml.

A 'cup' is 8 oz (240&nbsp;ml.)

## Different ways to get 200mg of caffeine 
## References 
## Other websites 
### Scientific information 
* eMedicine Caffeine-Related Psychiatric Disorders
* The Consumers Union Report on Licit and Illicit Drugs, Caffeine-Part 1  Part 2 
* *The Physician and Sportsmedicine*: Caffeine: A User's Guide 
* Caffeine: Psychological Effects, Use & Abuse 
* Caffeine Withdrawal Recognized as a Disorder 
* Is Caffeine a Health Hazard?

### Others 
* Caffeine Withdrawal Symptoms 
* Caffeine: How Stuff Works
* Caffeine: The most popular psychoactive drug, Broke but Shredded, January 2022 
* Erowid Caffeine Vaults
* #caffeine! - The Caffeine Information Archive 
* Naked Scientists Online: Why do plants make caffeine?
* Alcohol and Drugs History Society: Caffeine news page
* Coffee: A Little Really Does Go a Long Way, NPR, September 28, 2006
* Does coffee really give you a buzz? by John Triggs in the Daily Express April 17 2007
* Burgower, Rachael. “The Effects of Energy Drinks on Sleep and Daily Functioning.” , 2014, pp.&nbsp;1–59. 

### News 
* National Post: Caffeine linked to psychiatric disorders