Rosalind Franklin

**Rozalind Elsi Franklin** (; 25. jul 1920 — 16. april 1958) je bila britanski biofizičar i kristalograf. Njen rad sadrži ključni doprinos razumevanju fine molekulske strukture DNK, RNK, virusa, uglja i grafita. Najpoznatija je po radu na DNK jer dezoksiribonukleinska kiselina ima esencijalne uloge u ćelijskom metabolizmu i genetici. Otkriće njene strukture je pomoglo naučnicima da razumeju način na koji se genetička informacija prenosi sa roditelja na decu.

Franklin je najpoznatija po njenom difrakcionom snimku DNK koje je dovelo do otkrića DNK dvostrukog heliksa. Njeni podaci su prema izjavi Fransisa Krika korišćeni 1953. za formulisanje hipoteze o strukturi DNK. Franklinovi snimci difrakcije X-zraka koji su potvrdili heliksnu strukturu DNK su pokazani Votsonu bez njenog odobrenja ili znanja. Mada su taj snimak i njena precizna interpretacija pružili značajan uvid u DNK strukturu, njen naučni doprinos tom otkriću se retko navodi. Njen neobjavljeni manuskript pokazuje da je ona nezavisno utvrdila sveukupnu B-formu DNK heliksa i lokaciju fosfatnih grupa na obodu strukture.

Nakon rada na DNK, Franklin je izučavala viruse mozaika duvana i polio. Ona je umrla 1958 usled komplikacija izazvanih rakom jajnika.

## Reference

## Literatura

* Bryson, B. *A Short History of Nearly Everything.* (2004). Black Swan .
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* Crick, F. H. C. *What Mad Pursuit*, (1988). Basic Books. .
* Elkin, L., O. *[http://scitation.aip.org/getpdf/servlet/GetPDFServlet?filetype=pdf&id=PHTOAD000056000003000042000001&idtype=cvips Rosalind Franklin and the Double Helix] Physics Today* March 2003, pp.&nbsp;42–48.
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* Ferry, Georgina, 2007. Max Perutz and the Secret of Life. Published in the UK by Chatto & Windus (), and in the USA by the Cold Spring Harbor Laboratory Press.
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* Franklin, R.E. and Gosling, R.G. authors of papers received 6 March 1953: Acta Cryst. (1953). 6, 673 The Structure of Sodium Thymonucleate Fibres I. The Influence of Water Content II. The Cylindrically Symmetrical Patterson Function
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* Holt, J. (2002) "Photo Finish: Rosalind Franklin and the great DNA race" *The New Yorker* October
* Judson, Horace Freeland, "The Eighth Day of Creation:Makers of the Revolution in Biology" (London: Jonathan Cape,1979), Penguin,1995; expanded edition; New York:Cold Spring Harbor Press, 1996).
* Brenda Maddox *Rosalind Franklin: The Dark Lady of DNA* (2002). Harper Collins .
* Nobel Prize (1962). *[http://nobelprize.org/medicine/laureates/1962/index.html The Nobel Prize in Physiology or Medicine 1962]*, *for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material*, Nobelprize.org
* Olby, R., "The Path to the Double Helix" (London:Macmillan,1974)
* Sayre, A. 1975. *Rosalind Franklin and DNA*. New York: W.W. Norton and Company. .
* Tom Segev *One Palestine, Complete*, (2000) () Abacus History.
* Stent, Gunther, editor. "Critical Edition of The Double Helix"(1980) W.W. Norton Co, New York and London. .
* Watson, J. Letter to *Science*, *164*, pp.&nbsp;1539, 27 (1969).
* Maurice Wilkins, *The Third Man of the Double Helix, an autobiography* (2003) Oxford University Press, Oxford. .
* Yockey, H. P. *Information Theory, Evolution, and the Origin of Life* (2005).

## Vanjske veze

* CWP at UCLA
* Rosalind Franklin