Enterobakterijski fag T4

**Enterobakterijski fag T4** je bakteriofag koji može da inficira bakteriju *[[E. coli]]*. Njegov dvolančani DNK genom je oko 169 kbp dugačak i sadržan je u ikosaedarskoj glavi, poznatoj kao kapsid. T4 je relativno veliki fag, aproksimativno 90 nm u širok i 200&nbsp;nm dugačak (većina fagova ima dužinu u opsegu od 25 do 200&nbsp;nm). Vlakna njegovog repa omogućavaju vezivanje za ćeliju domaćina. Rep T4 faga je šupalj, tako da nukleinska kiselina prolazi kroz njega pri ulasku u ćeliju. T4 ima jedino sposobnost sprovođenja litičkog, a ne i lizogenog životnog ciklusa.

## Reference

## Literatura

* T4 Bacteriophage Infection Process Animations - Copyright © 2004-2009 by http://www.seyet.com/bacteriophage-t4
* Leiman, P.G., Kanamaru, S., Mesyanzhinov, V.V., Arisaka, F., and Rossmann, M.G., "Structure and morphogenesis of bacteriophage T4."https://commerce.metapress.com/content/agh59p6ck92yu1df/resource-secured/?target=fulltext.pdf&sid=hcdyjszn4a5lch552m5hysqe&sh=www.springerlink.com
* Karam, J., Petrov, V., Nolan, J., Chin, D., Shatley, C., Krisch, H., and Letarov, A. The T4-like phages genome project. http://phage.bioc.tulane.edu/ . * (The T4-like phage full genomic sequence depository)*
* Mosig, G., and F. Eiserling. 2006. T4 and related phages: structure and development, R. Calendar and S. T. Abedon (eds.), The Bacteriophages. Oxford University Press, Oxford. *(Review of phage T4 biology)* 
*  *(Indication of prevalence and T4-like phages in the wild)*
*  *(Characterization of a T4-like phage)*
* 
*  *(Review of phage T4, from the perspective of its genome)*
*  *(Overview of the RB49 genome, a T4-like phage)*
*  *(T4 phage application in biotechnology for studying protein interaction)*
*  *(Indication of the prevalence of T4-type sequences in the wild)*
*  *(Historical description of the isolation of the T4-like phages T2, T4, and T6)*
*  *(Nearly complete list of then-known T4-like phages)*
*  *(Overview of various T4-like phages from the perspective of their genomes)*
*  *(Comparison of the genomes of various T4-like phages)*
* Karam, J. D. *et al.* 1994. Molecular Biology of Bacteriophage T4. ASM Press, Washington, DC. *(The second T4 bible, go here, as well as Mosig and Eiserling, 2006, to begin to learn about the biology T4 phage)* 
* Eddy, S. R. 1992. Introns in the T-Even Bacteriophages. Ph.D. thesis. University of Colorado at Boulder. *(Chapter 3 provides overview of various T4-like phages as well as the isolation of then-new T4-like phages)*
* Surdis, T.J "et al" Bacteriophage attachment methods specific to T4, analysis, Overview.
* Mathews, C. K., E. M. Kutter, G. Mosig, and P. B. Berget. 1983. Bacteriophage T4. American Society for Microbiology, Washington, DC. *(The first T4 bible; not all information here is duplicated in Karam *et al.*, 1994; see especially the introductory chapter by Doermann for a historical overview of the T4-like phages)* 
* Russell, R. L. 1967. Speciation Among the T-Even Bacteriophages. Ph.D. thesis. California Institute of Technology. *(Isolation of the RB series of T4-like phages)*
*  *(rare type of translational regulation characterized in T4)*
*  *(T4-like phage isolation, including that of phage Ox2)*

## Povezano
* T4 ''rII'' sistem

## Vanjske veze
* '''Viralzon''': T4-slični viruis