Lupus na ime ime

**Lupus na idi ime na ebute ihe isi Ike di iche iche n'ebe nne na NWA no.**. 

Ọ bụ ezie na ọtụtụ ụmụ ọhụrụ ndị nne nwere lupus mụrụ nwere ahụike, ndị nne nwere Lupus dị ka ọrịa dịbu adị n'oge dị ime kwesịrị ịnọgide na-enwe nlekọta ahụike ruo mgbe ha mụrụ nwa. N'ozuzu, ụmụ nwanyị na-arịa lupus na, na mgbakwunye, ọbara mgbali elu, proteinuria, na azotemia nwere ihe ize ndụ dị ukwuu maka nsogbu ime ime,   gụnyere ime ọpụpụ, ịmụ nwa nwụrụ anwụ, pre-eclampsia, ịmụ nwa n'oge, na Mgbochi uto intrauterine.  Nsonaazụ ime n'ime ụmụ nwanyị nwere lupus ndị na-anata transplantation nke akụrụ yiri nke ndị na-anabata transplantation na-enweghị lupus.[2]

Ụmụ nwanyị dị ime na ndị a maara na ha nwere anti-Ro (SSA) ma ọ bụ anti-La antibodies (SSB) na-enwekarị echocardiograms n'oge izu nke 16 na nke 30 nke ime ime iji nyochaa ahụike nke obi na vasculature gbara ya gburugburu.

A na-adụ ndị inyom na-arịa lupus ọdụ mgbe niile iji gbochie ime ime na ụdị ndị ọzọ a pụrụ ịdabere na ha, ebe ọ bụ na a chọpụtara na ime ime n'oge ọrịa na-arụ ọrụ na-emerụ ahụ. Lupus nephritis bụ ngosipụta a na-ahụkarị.

N'ime ụmụ a mụrụ dị ndụ, a na-amụ ihe dịka otu ụzọ n'ụzọ atọ n'oge.

## Ime ime ọpụpụ
Lupus na-akpata mmụba nke ọnwụ nwa e bu n'afọ *n'ime akpa nwa* na ite ime na-enweghị isi (mgbapụta ime). A na-eme atụmatụ na ọnụọgụ ọmụmụ dị ndụ n'ozuzu ya na onye nwere lupus bụ 72%. Nsonaazụ ime yiri ka ọ ka njọ na ndị nwere lupus nke ọrịa ha na-arị elu n'oge ime.

Ọpụpụ ime n'ime ọnwa atọ mbụ yiri ka ọ nweghị ihe kpatara ya ma ọ bụ na ọ nwere njikọ na ihe ịrịba ama nke lupus na-arụ ọrụ. Mfu ndị ọzọ yiri ka ọ na-eme n'ihi ọrịa antiphospholipid, n'agbanyeghị ọgwụgwọ heparin na aspirin.[1] A na-atụ aro ka ụmụ nwanyị niile nwere lupus, ọbụlagodi ndị na-enweghị akụkọ ihe mere eme nke ime ọpụpụ, nyochaa ha maka antiphospholipid antibodies, ma lupus anticoagulant (RVT na PTT dị nro bụ batrị nyocha kachasị mma) na antibodies anticardiolipin.[1]

## Lupus nwa ọhụrụ
Neonatal lupus bụ ihe mgbaàmà lupus na nwa ọhụrụ a mụrụ site na nne nwere lupus, nke na-enwekarị rash yiri diskoid lupus erythematosus, na mgbe ụfọdụ na nsogbu sistemụ dịka nkwụsị obi ma ọ bụ hepatosplenomegaly. Lupus nwa ọhụrụ na-abụkarị nke na-adịghị njọ ma na-egbochi onwe ya.[1] N'agbanyeghị nke ahụ, ịchọpụta ndị nne nọ n'ihe ize ndụ kachasị elu maka nsogbu na-enye ohere maka ọgwụgwọ ngwa ngwa tupu ma ọ bụ mgbe amuchara. Na mgbakwunye, lupus nwere ike ịmalite n'oge ime, ọgwụgwọ kwesịrị ekwesị nwere ike ime ka ahụike nne dị ogologo.

## Mmetụta nke lupus
Aggravation (or exacerbation) of lupus has been estimated to occur in about 20-30% pregnancies where the mother has lupus. Increased disease activity of lupus is expected during pregnancy because of increased levels of estrogen, prolactin, and certain cytokines. However, a long time of remission before pregnancy decreases the risk of aggravation, with an incidence of 7-33% in women who have been in remission for at least 6 months, and an incidence of 61-67% in women who have active lupus at the time of conception.

Ọrịa akụrụ na-agbawa bụ ngosipụta a na-ahụkarị nke lupus na-akawanye njọ n'oge ime ime, a na- hụkwa ya na United States na ndị Europe. A na-ahụ serositis na pleural na pericardial effusions na ihe ruru 10% nke ndị ọrịa a.[1]

N'aka nke ọzọ, ọkụ nke lupus adịghị ahụkebe n'oge ime ma na-agwọkarị ya n'ụzọ dị mfe. Mgbaàmà ndị a na-ahụkarị nke flares ndị a gụnyere arthritis, rashes, na Ike ọgwụgwụ.[1]

Ọzọkwa, n'oge postpartum, enwere ike inwe mgbagwoju anya nke lupus n'ihi mbelata nke steroid na-egbochi ọzịza, ọkwa dị elu nke prolactin na Estrogen na mgbanwe progesterone.

N'ịchọpụta mmụba nke lupus n'ime ime, ọ dị mkpa inwe nchọpụta dị iche site na nsogbu ndị na-enweghị njikọ lupus nke ime ime nke nwere ike ịpụta n'ụzọ yiri nke ahụ. Dịka ọmụmaatụ, Chloasma nwere ike ịpụta dị ka malar rash nke lupus, proteinuria sitere na preeclampsia nwere ike ịpụ dị ka nke lupus nephritis, thrombocytopenia nke Ọrịa HELLP nwere ike ịdị ka nke lupos, na mgbu nke nkwonkwo metụtara ime nwere ike ịbịakwute dị ka arthritis nke lupus.

## Nzọụkwụ mgbochi n'ozuzu
Ina anu glucocorticoids n'obere ya nga ona Aru oru maobu ipacha Anya n'inu azathioprine but ihe ana agwa ufodu ndi mmadu, ma na agwa kwa ha Maka ihe do njo ogwu ahu nwere Ike ime n'ahu mmadu.
Òtù:Pages with unreviewed translations