Ejiji ọgwụ nke fungus

thumb|Ero,
fungi ọgwụ bụ fungus nke nwere metabolites ma ọ bụ enwere ike ime ka ọ mepụta metabolites site na biotechnology iji ịzulite Ndenye ọgwụ Ngwakọta ndị e mepụtara nke ọma n'ime ọgwụ ma ọ bụ n'okpuru nyocha gụnyere ọgwụ nje, ọgwụ mgbochi ọrịa kansa, cholesterol na ergosterol synthesis inhibitors, ọgwụ psychotropic, immunosuppressants na fungicides.

## Akụkọ ihe mere eme
 N' agbanyeghị  na a n'eji ngwaahịa fungus eme ihe na ọgwụ ọdịnala, ikike ịchọpụta ihe bara uru ma wepụ ihe na-arụ ọrụ malitere site na nchọpụta penicillin site na Alexander Fleming n'afọ 1928. Kemgbe ahụ, a chọtara ọtụtụ ọgwụ nje nwere ike ime na ikike maka fungi dị iche iche iji mepụta mkpụrụ ndụ na-arụ ọrụ nke ọma na usoro ọgwụgwọ dị iche iche kemgbe n'eme nnyocha. nyocha Ọgwụ chọpụtara ihe ndị n'Igbochi nje, nje virus, na ihe ndị n'egbochi nje virus site na nje fungus.

*Ganoderma lucidum*, nke a maara na Chinese dị ka líng zhī ("osisi mmụọ"), na n'ime Japanese dị ka mannentake ("ero10,000-afọ"), amụọla ya nke ọma.   &#x5B;**'&#x5D;</sup> Ụdị ọzọ nke genus''Ganoderma'', ''G. applanatum'', ka nọ n'okpuru nyocha bụ isi.   <sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#x5B;**'&#x5D; E ji *Inonotus obliquus* mee ihe na Russia na mmalite narị afọ nke iri na isii; ọ pụtara na akwụkwọ akụkọ Alexander Solzhenitsyn nke 1967 Cancer Ward . 

## Nnyocha na mmepe ọgwụ

### Ọrịa kansa
Enweghị ezigbo ihe akaebe  ụdị ero ma ọ bụ ihe ọ bụla e wepụrụ na eto nwere ike igbochi ma ọ bụ gwọọ kansa.

,11'-Dideoxyverticillin A, nke dịpụrụ adịpụ nke *Penicillium* mmiri, ejiri ya mepụta ọtụtụ ihe n'egbochi ọrịa kansa. ,11'-Dideoxyverticillin A, andrastin A, barceloneic acid B">barceloneic acid A, na barcelonelic acid B, bụ ndị n'egbochi farnesyl transferase nke *Penicillium* nwere ike ime. 3-O-Methylfunicone, anicequol, duclauxin, na rubratoxin B, bụ ihe n'egbochi ọrịa kansa / cytotoxic metabolites nke *Penicillium*.   &#x5B;**'&#x5D;</sup>

''Penicillium'' bụ isi iyi nke ọgwụ leukemia asparaginase.

 Ụfọdụ Mba akwadowo beta-glucan fungal extracts lentinan, polysaccharide-K, na Polysaccharide peptide dị ka Ihe enyemaka n'ahụ maka ahụike.

=== Ihe n'egbochi nje (ihe na-egbu nje) ===
Alexander Fleming duziri ụzọ maka Ọgwụ nje beta-lactam ya na  ''Penicillium'' ebu na penicillin. Nchọpụta ndị sochirinụ gụnyere alamethicin, aphidicolin, brefeldin A, cephalosporin,  cerulenin, citromycin, eupenifeldin, fumagillin, [1] fusafungin, fusidic acid, [2] helvolic acid, [3] itaconic acid, MT81, nigrosporin B, usnic acid, Verrucarin A, vermiculin na ọtụtụ ndị ọzọ.

Antibiotics retapamulin, tiamulin, na valnemulin bụ ihe ndị sitere na fungal metabolite pleuromutilin. Plectasin, austrocortilutein, austrocortirubin, coprinol, oudemansin A, strobilurin, Illudin, pterulone, na sparassol nọ n'okpuru nyocha maka ọrụ ọgwụ nje ha.   <sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#x5B;**'&#x5D;

### Ndị n'egbochi cholesterol biosynthesis
thumb|osikapa na-acha ọbara ọbara, ''Monascus purpureus'', nwere ike ịmepụta statins atọ.
Statins bụ ụdị dị mkpa nke ọgwụ n'ebelata cholesterol; ọgbọ mbụ nke statins sitere na fungus. Lovastatin, statin mbụ nke azụmahịa, ka e si na ofe gbara uka nke *Aspergillus terreus* wepụta. Mmepụta  ụlọ ọrụ ugbua  nwere ike ịmepụta 70 mg lovastatin kwa kilogram nke ihe nkedo. &nbsp;Mkpụrụ osikapa na-acha ọbara ọbara, *Monascus purpureus*, nwere ike ịmepụta lovastatin, mevastatin, na onye n'ebute simvastatin monacolin J. Nicotinamide riboside, onye n'egbochi cholesterol biosynthesis, bụ nke *Saccharomyces cerevisiae* na-eme.   &#x5B;**&#x5D;

### Ndị na-emegide ịkwa iko