Gimbiya Imoukhuede

**Gimbiya Imoukhuede** (wanda aka fi sani da I-muh-KWU-e-de) (an haife ta a shekara ta 1980) injiniyan sinadarai ce 'yar Amurka wacce Farfesa ce a fannin Bioengineering a Jami'ar Washington a matsayin Shugabar Hunter da Dorthy Simpson. Tana gudanar da bincike mai zurfi kan siginar angiogenic da ilimin halittar jijiyoyin jini. Dakin gwaje-gwajenta yana amfani da ilimin tsarin adadi don fahimtar da kuma sarrafa hanyoyin sadarwa na siginar da ke haifar da samuwar jijiyoyin jini, da nufin haɓaka magunguna ga cututtuka kamar ciwon daji da cututtukan zuciya. Aikin Imoukhuede ya sami kyaututtuka da yawa, gami da Kyautar Gidauniyar Kimiyya ta Kasa da Kyautar CEERER da Kyautar Mid-Career Society, da Kyautar Jagoranci Mai Girma ta Illinois Mathematics and Science Academy da Kyautar Nano Research Young Innovators Award ta 2018 a fannin Nanobitechnology, tare da yaba da muhimmiyar gudummawar da ta bayar ga tallafin karatu, ilimi, da jagoranci. Sunanta na farko shine 'Gimbiya' duk da haka, ba ta da wani matsayi na sarauta ko matsayi a kowane matsayi.

## Rayuwar farko da ilimi
Imoukhuede ta girma a Matteson, Illinois .  Tana da hannu a wasannin tsere da filin wasa tun tana ƙarama, kuma tana fafatawa a wasan harbi tun tana ɗan shekara takwas. A lokacin da take aji takwas, ta fara sha'awar kimiyya, kuma iyayenta sun ba ta saitin sinadarai don yin wasa da su a gida.  Imoukhuede ta halarci Kwalejin Lissafi da Kimiyya ta Illinois .  Imoukhuede ɗaliba ce mai digiri na farko a fannin injiniyan halittu a Cibiyar Fasaha ta Massachusetts (MIT), inda ta yi bincike na digiri na farko a ƙarƙashin kulawar Robert S. Langer kan haɗa adenoviruses a cikin tsarin maganin kwayoyin halitta da ke tushen liposome. A shekararta ta farko ta sami karramawa a Babban Taron Wasannin Kwaleji na Gabashin, kuma ita ce mace ta farko daga MIT da ta cancanci shiga Ƙungiyar Wasannin Kwaleji ta Ƙasa . &#x5B; **' &#x5D;</sup> Lokacin da yake MIT, Imoukhuede ya shiga wasannin motsa jiki, yana aiki a matsayin kyaftin na ƙungiyar tseren gudu da filin wasa ta jami'ar, kuma an naɗa shi ɗan wasa na NCAA All-American. Roger Crosley, Daraktan Wasanni na MIT a wancan lokacin, ya bayyana Imoukhuede a matsayin "mafi kyawun mai jefa nauyi da muka taɓa samu a tseren gudu da filin wasa". <sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#x5B; **' &#x5D; Bayan ta sami digirin farko, Imoukhuede ta koma Cibiyar Fasaha ta California, inda ta yi aiki tare da Henry A. Lester kan tsarin mai jigilar GABA da kuma canja wurin makamashin Förster .  Ita ce mace ta farko 'yar Afirka Ba'amurke da ta sami digirin digirgir a fannin injiniyan halittu daga Caltech . 

## Bincike da aiki
Imoukhuede daliba ce ta digirin digirgir a Jami'ar Johns Hopkins, inda ta ƙware a fannin injiniyan likitanci a dakin gwaje-gwaje na Aleksander Popel.  Ta kasance ɗaya daga cikin ɗaliban digirin digirgir 10 a duk faɗin ƙasar da ta sami lambar yabo ta United Negro College Fund/Merk Postdoctoral Fellowship. A lokacin karatunta na digirin digirgir, ta fara aiki a kan vascular endothelial growth factor (VEGF) da kuma its receptor (VEGFR) a fannin ischemia da ciwon daji. Bayan kammala bincikenta na digiri na uku, Imoukhuede ta shiga Jami'ar Illinois da ke Urbana–Champaign .  A halin yanzu, Imoukhuede farfesa ce a fannin injiniyan halittu a Jami'ar Washington a matsayin Hunter da Dorthy Simpson Endowed Chairman. 

Imoukhuede ta yi nazarin hanyoyin da ke daidaita siginar angiogenic, gami da masu karɓar tyrosine kinase, masu karɓar VEGF da masu karɓar haɓakar platelet . A cikin 2019 Imoukhuede da Sarah K. England sun haɗu don inganta inganci da amincin oxytocin yayin nakuda.  Imoukhuede tana haɓaka samfurin lissafi wanda za a iya amfani da shi don annabta aikin oxytocin receptor.  Abin da take mayar da hankali a kai a yanzu shi ne warware sarkakiyar da ke jagorantar samuwar jijiyoyin jini wanda ke ba da damar magani ga cututtuka da dama kamar ciwon nono da wasu cututtukan zuciya da jijiyoyin jini .  Tun daga shekarar 2025, Imoukhuede ta fara ƙirƙiro samfurin lissafi don nemo mafi kyawun maganin oxytocin, musamman a lokacin daukar ciki. 

### Lambobin yabo da girmamawa

* Kyautar Ajin MIT na 1972 
** An bayar da wannan lambar yabo ne ga wani aiki da ya fi inganta rayuwar mutane ko kuma wanda ke amfanar muhalli.
* Kyautar Jajircewa ga Bambancin Ra'ayi ta 2008, Caltech 
* 2008 UNCF Merck Postdoctoral Research Fellowship 
* Wanda aka ba kyautar Biyan Lamuni na NIH na 2009 don Binciken Asibiti 
* Kyautar Poster ta taron Gordon na 2011 Angiogenesis 
* 2013-2015 American Cancer Society, Sashen Illinois, Tallafin Bincike na Asali 
* 2015 NIH-NIDDK, Kyautar Bincike ta Asali 
* Kyautar Rose ta 2017 don Ingantaccen Koyarwa ta  Kwalejin Injiniya ta Jami'ar Illinois 
* Kyautar Aikin Gidauniyar Kimiyya ta Ƙasa ta 2017 
* Wanda ya lashe kyautar jagoranci ta IMSA ta 2018 
* Matashin Mai Ƙirƙira a Fasahar Nanobio ta 2018 
* 2019 Cibiyar Nazarin Injiniyoyi Masu Sinadarai ta Amurka Mai Bincike kan Gaba 
* Mai ba da shawara kan wayar salula na shekarar 2020 ya nada Imoukhuede a matsayin daya daga cikin "masana kimiyya bakar fata masu kwarin gwiwa" 1,000 
* Kyautar Mai Ba da Bayani Kan Sabbin Dabaru da Wahayi Masu Tasiri (HI3) ta 2020 
** An gabatar da ita ne ta hanyar Cibiyar Injiniya ta Mata Masu Digiri na Jami'ar Pittsburgh
* Kyautar Tsakiyar Aiki ta Ƙungiyar Injiniyan Halittu ta 2021 
** Wannan lambar yabo tana karrama membobin da suka nuna jajircewa wajen samun nasarori a fannin ilimi, ilimi, da jagoranci
* Cibiyar Koyarwa ta Jami'ar Illinois ta karrama Imoukhuede a matsayin Malami Mai Kyau 

### Littattafai da aka zaɓa
Littattafan ta  sun haɗa da:

* *Fataucin Ƙananan Kwayoyin Halitta, Haɗakar Pentameric, da Tsarin Subunit na Neuronal Nicotinic Acetylcholine Masu Rarraba Acetylcholine Masu ɗauke da Ƙananan α6 da β3 Masu Lakabi Mai Haske* 
* *Ƙididdigewa da bambancin ƙwayoyin halitta zuwa ƙwayoyin halitta na masu karɓar ƙwayoyin halittar jijiyoyin jini na endothelial growth factor* 
* *Magungunan magani da kuma pharmacodynamics na ƙwayoyin rigakafi masu rage VEGF* 
* *Bambancin jinsi a cikin hanyoyin cutar kansa* 

### Haƙƙin mallaka

* Morales, R., Sherin, RS, **Imoukhuede, PIU,** Burke, D., Gomez, M., Ramirez, DL, Castaneda, A. (2003). Tsarin gini don gine-gine (A63H 033/08 bugu, Haƙƙin mallaka na Amurka 6,641,453). Amurka: Kwalejin Kimiyyar Aiwatarwa. 

## Manazarta