Angela Vincent

**Angela Vincent** (an haife ta a shekara ta 1942)masaniyar kimiyyar kwakwalwa ce ta Burtaniya wacce ta kasance farfesa a Jami'ar Oxford kuma Fellow na Kwalejin Somerville, Oxford.

## Ayyuka da bincike
An haifi Angela Vincent a shekarar 1942, ta uku ta Carmen da Joseph Molony (daga baya KCVO). Bayan St Mary's Convent, Ascot, ta yi karatun magani a Kwalejin King's London da Westminster Hospital School of Medicine (yanzu an haɗa ta da Makarantar Kwalejin Imperial College of Medicine). Bayan shekara guda a matsayin ƙaramin likita a asibitocin St Steven da St Charles a London (1966-1967), ta sami MSc a cikin ilmin sunadarai daga Kwalejin Jami'ar London. A shekara ta 1967 ta auri Philip Morse Vincent kuma suna da 'ya'ya hudu.

Bayan MSc, ta shafe shekaru uku masu takaici tana ƙoƙarin raba sinaptosomes na kwakwalwar bera, har sai Ricardo Miledi FRS ya ɗauke ta a sashen biophysics don aiki a kan masu karɓar acetylcholine. A cikin shekaru biyar da ta yi tare da Miledi, bayanan likitancinta ya taimaka wajen kafa hadin gwiwa kan myasthenia gravis tare da John Newsom-Davis (daga baya FRS); tare a Royal Free Hospital, London, sun kirkiro ƙungiyar neuroimmunology wacce daga baya ta koma tare da Newsom-David zuwa Oxford lokacin da aka nada shi farfesa na bincike na neurology. Bayan ya yi ritaya a shekarar 1998, Vincent ya jagoranci kungiyar har zuwa 2016. A wannan lokacin ta kasance shugabar sashen ilimin jijiyoyin asibiti (2005-2008) a Jami'ar Oxford, shugabar International Society of Neuroimmunology (2001-2004), kuma mataimakiyar edita ta *Brain* (2004-2013).  Kungiyar bincikenta ta fara ne a Cibiyar Weatherall ta Molecular Medicine a asibitin John Radcliffe, tana aiki a kan fannoni daban-daban na ilimin halittu wanda ya kunshi ilmin halitta, ilmin halitta na Kwayoyin halitta, ilkin rigakafi na sel da ilmin jijiyoyin intracellular. Binciken kungiyar ya mayar da hankali kan cututtukan rigakafi da Cututtukan kwayar halitta na mahaɗin neuromuscular, jijiyoyin da ke kusa da kuma kwanan nan filin da ke da ban sha'awa na cututtukani na tsakiya. Manyan cututtukan rigakafin da aka yi nazari sune myasthenia gravis, cutar Lambert-Eaton myasthenic, limbic encephalitis, wasu nau'ikan autoimmune encephalitis da kuma neuromyotonia.

Ta ba da gudummawa a kan matsayin rigakafin da aka tsara akan masu karɓar acetylcholine da takamaiman kinase na tsoka (MuSK) a cikin myasthenia gravis, da masu karɓar glycine ko sunadarai masu alaƙa da tashar potassium LGI1, CASPR2 da Contactin-2 a cikin cututtukan CNS.

Ta nuna cewa canja wurin antibodies a fadin placenta daga mace mai ciki zuwa tayin a cikin mahaifa na iya haifar da cututtukan neuromuscular da neurodevelopmental na dogon lokaci.

Tun daga shekara ta 2016 ta kasance Farfesa mai daraja a Jami'ar Oxford, Fellow mai daraja na Kwalejin Somerville, kuma tana da alƙawari na girmamawa a UCL; ta ci gaba da aiki a kan cututtukan jijiyoyi da kuma ba da shawara ga matasa masu bincike. Ayyukanta a Oxford kan rikicewar kwakwalwa sun ci gaba a karkashin Mataimakin Farfesa Sarosh Irani da Dokta Patrick Waters .

Ita mai goyon baya ne mai karfi na Freedom from Torture (tsohon The Medical Foundation for Treatment of Torture Victims) kuma Patron na British Pugwash (wanda ke tattara masana kimiyya da wasu da ke da damuwa da al'amuran kasa da kasa da kuma kawar da makamai).

### Kyaututtuka da girmamawa
A shekara ta 2009, ta gabatar da jawabin Leslie Oliver a Asibitin Sarauniya.[1] A shekara ta 2009, ta sami lambar yabo ta Association of British Neurologists kuma a cikin 2017, lambar yabo ta World Federation of Neurology Scientific Contributions to Neurology. A shekara ta 2015, an ba ta lambar yabo ta British Neuroscience Association Award for Outstanding Contribution to Neuroscience . [2] A Cologne 2018, an ba ta lambar yabo tare da J Posner da J Dalmau, Kyautar Kasa da Kasa don Fassarar Neuroscience na Gidauniyar Gertrud Reemtsma (tsohon Kyautar Klaus Joachim Zülch), kuma a Washington a cikin 2019, Kyautar Binciken Kimiyya ta Asibiti ta Amurka (tare da J Dalma). [3] Ta sami lambar yabo ta Inaugural Distinguished Alumni, Kwalejin Imperial, London, 2020 da kuma lambar yabo ta Life-time na Jamusanci Neurological Society (DGN) a cikin 2021. A shekara ta 2002, an zabe ta Fellow na Kwalejin Kimiyya ta Kiwon Lafiya (FMedSci) kuma a shekara ta 2011, Fellow na Royal Society (FRS). [4][5]

## Manazarta