Tayyaba Hasan

**Tayyaba Hasan** farfesa ce a fannin cututtukan fata a Cibiyar Wellman don Photomedicine a Makarantar Kiwon Lafiya ta Harvard da Babban Asibitin Massachusetts (wani ɓangare na Mass Janar Brigham aka MGB). Har ila yau, Farfesa ce a fannin kimiyyar kiwon lafiya da fasaha a Harvard-MIT (HST). 

Hasan yana daya daga cikin masu kirkirar Visudyne (aka Verteporfin), Hukumar Abinci da Magunguna da ta amince da magani don lalacewar ido mai alaƙa da shekaru, wanda aka yi amfani da shi don kula da miliyoyin marasa lafiya a duk duniya. An san ta a matsayin jagora a fagen maganin photodynamic (PDT) a duk duniya,  Hasan ta kasance mai bincike mai aiki sama da shekaru 40, ta sami kyaututtuka da yawa masu mahimmanci don bincikenta da jagoranci, kwanan nan lambar yabo ta Shugaban Amurka don Kwarewa a Kimiyya, Lissafi da Injiniya (PAESMEM). Hasan yana da littattafai sama da 300 (wanda aka ambata fiye da sau 36k),  30+ abubuwan kirkirar, kuma yana da Fellow na duka National Academy of Inventors da OSA (tsohon Optical Society of America). 

## Rayuwa ta farko da ilimi
Hasan ta kammala digiri na farko a fannin ilmin sunadarai a Jami'ar Karachi a shekarar 1966.  Ta sami digiri na biyu a shekarar 1968, ta ƙware a fannin ilmin sunadarai. A shekara ta 1970 Hasan ya sami digiri na biyu a fannin ilmin sunadarai daga Jami'ar Islamabad (wanda yanzu ake kira Jami'ar Quaid-i-Azam).  Ta lashe tallafin karatu na kasa da yawa daga Gidauniyar Ilimi ta Punjab da Jami'ar Punjab . Ta koma Jami'ar Arkansas don bincikenta na digiri, inda ta sami digirinta na PhD a fannin ilmin sunadarai na jiki a shekarar 1980.  An zabe ta zuwa Sigma Xi .  Har ila yau, tana da digiri na girmamawa daga Jami'ar Harvard da aka bayar a shekara ta 2000.

## Bincike
Bayan kammala karatunta na PhD, Hasan ta shiga Jami'ar Pennsylvania a matsayin mai bincike na postdoctoral a sashen ilmin sunadarai. Ta shiga Makarantar Kiwon Lafiya ta Harvard a shekarar 1982. Hasan ya yi aiki tare da Alan Oseroff a kan maganin rigakafi na photosensitization na sel don photolysis mai karɓa. Ta nuna cewa yana yiwuwa a yi niyya ga tsarin ƙwayoyin halitta ta hanyar photosensitization. Kokarin kimiyya na Hasan yana mai da hankali kan hanyoyin da suka danganci photochemistry (maganiyar hoto, ko PDT) don magani da ganewar asali na ciwon daji da kamuwa da cuta ta amfani da dabarun da aka yi niyya, musamman nanotechnology. Ta horar da likitocin fata, likitocin ido, likitoci na urologists, likitofin mata da likitoci.

Ta nuna cewa ana iya amfani da abubuwan da aka samo daga benzoporphyrin a cikin ido don kawar da tasoshin subretinal. Ta ci gaba da gano Visudyne tare da Ursula Schmidt .  Visudyne na ɗaya daga cikin takardun shaida na Amurka sama da talatin da Hasan ke riƙewa. An shigar da ita a matsayin Fellow a cikin Kwalejin Inventors ta Kasa a cikin 2018 sakamakon abubuwan kirkirarta da yawa. An nada ta a matsayin farfesa a fannin cututtukan fata a HMS da MGH a shekarar 2009. A shekara ta 2011 ta kaddamar da abin da ke yanzu wani ɓangare na ECOR a matsayin darektan kafa Ofishin Ci gaban Ayyuka na Bincike a Babban Asibitin Massachusetts .  

Tana yin niyya ga cututtuka irin su leishmaniasis, mycobacterium tuberculosis, methicillin-resistant Staphylococcus aureus da kuma ciwon daji na pancreas da fata .  Lab din Hasan yana mai da hankali kan hanyoyin photophysical da na halitta na maganin photodynamic. Babban dabarun shine haɓaka hanyoyin kwayoyin halitta da tsarin haɗin gwiwar hoto inda hannu ɗaya na magani ya haɗa da kunna haske na wasu sunadarai masu amfani da infrared. An tsara wannan don gano manufofi daban-daban na salula da kwayoyin don takamaiman cututtuka da ƙirar ƙira don tasirin maganin photochemical mafi kyau. Tana jagorantar aikin Cibiyar Ciwon daji ta Kasa da ke tallafawa da yawa wanda ke mai da hankali kan maganin jagorantar hoto don cututtukan daji da fata. Wadannan sun hada da samar da iskar oxygen, da kuma asirin cytokine. Har ila yau, tana jagorantar ƙungiyar ƙasa da ƙasa da ke haɓaka fasahar farashi mai ƙarancin kuɗi don maganin hoto na ciwon daji na baki a cikin ƙananan saitunan albarkatu, ban da shirye-shiryen da aka fara da yawa.

Hasan Lab yana gudanar da ayyukan bincike na hadin gwiwa da yawa: 

* Ƙananan Ƙarfafa Kwayoyin Photodynamic Therapy don Ciwon daji na fata 
* Endoscopic Photodynamic da Combination Therapy don Ciwon daji na gida da Metastatic . 
* Tsarin Tsarin Tsarin Hadin Gishiri don Ciwon daji na Pancreatic 
* Misali-Based Dosimetry da Hotuna don PDT 

Jagoranta ya haɗa da manyan matsayi da yawa, kamar sharuɗɗa kamar Shugaba na American Society for Photobiology (ASP) , Co-Chairman da Shugaba na International Photodynamic Association (IPA), memba na Kwamitin Ba da Shawara na Kwamitin Shirye-shiryen Kungiyar Turai don Photobiology: ESP) da kuma Sashen Nazarin da yawa da kuma bangarorin bita na tallafi duka ga US NIH da kuma bangaren tallafin kasa da kasa. Ta ba da gudummawa ga littafin Photodynamic Therapy na 2014: Daga Ka'idar zuwa Aikace-aikace. Ta kuma yi aiki a kwamitin ba da shawara na Polythea . 

## Kyaututtuka

* Kyautar Shugaban kasa ta 2023 don Kyakkyawan Kimiyya, Lissafi da Injiniya Mentoring (PAESMEM), don nuna godiya ga jagorancinta da nasarorin kimiyya, ta Ofishin Fasaha da Fasaha na Fadar White House (OSTP) tare da Gidauniyar Kimiyya ta Kasa (NSF). 
* 2022 Gold Medal, gane muhimmiyar jagora da gudummawar aiki wanda ya inganta sosai fagen photodynamic therapy (PDT).  (Lifetime Achievement Award), ta Ƙungiyar Photodynamic ta Duniya.
* 2021 Thomas Dougherty Award for Excellence in PDT (Lifetime Achievement Award): a Taron Kasa da Kasa kan Porphyrins da Phthalocyanines, ICPP-11. 
* Kyautar Gold Medal for Excellence in Photobiological Research ga mashahuran masana kimiyya da suka ba da gudummawa mai mahimmanci ga European Society for Photobiology (ESP) (Lifetime Achievement Award). 
* 2019 "Tayyaba Hasan ImPAct Award", sanarwa ga ƙwarewa a fagen, mai suna don girmama ta, wanda aka ba da kyauta sau biyu a kowane Taron Duniya na IPA, a Taron Duniya ya IPA na 17, Cambridge, MA 
* 2019 Lifetime Achievement Award, wanda ya gane kyakkyawan aikin Babban mai bincike wanda aikinsa ya inganta fannonin bincike na ASP, ta American Society for Photobiology a Biennial Congress a Tampa FL 
* 2018 An gabatar da ita a matsayin Fellow Member saboda muhimmiyar gudummawar da ta bayar a fannin kimiyya da fasaha a matsayin bambanci ga aikinta na kirkiro. Wannan lambar yabo ta nuna masu kirkiro na ilimi waɗanda suka nuna ruhun kirkire-kirkire wajen kirkirar ko sauƙaƙe abubuwan kirkiro masu ban sha'awa waɗanda suka yi tasiri a kan ingancin rayuwa, ci gaban tattalin arziki, da jin daɗin al'umma ta Cibiyar Nazarin Inventors ta Kasa, a Houston, TX 
* 2018 An gabatar da shi a matsayin memba na Fellow don ci gaba a cikin babban filin photobiology, musamman don sababbin abubuwa a aikace-aikacen kayan aikin photophysical da photochemical don benci zuwa fassarar gado a cikin maganin photodynamic da hotuna, haɗa maganin photodynamics don aikace-aikace na kiwon lafiya na duniya da kuma kafa filin maganin photodynmic da aka yi niyya da kuma aiki tare da bambanci a cikin ci gaban gani da photonics, The Optical Society (wanda yanzu ake kira OSA). 
* 2018 American Society for Photobiology Lifetime Achievement Award wanda ke nuna kyakkyawan aikin babban mai bincike wanda aikinsa ya ci gaba sosai a fannonin bincike na American Society for Photobology 
* 2018 Britton Chance Biomedical Optics Award don nuna godiya ga gudummawar da aka bayar a fagen Photodynamic Therapy da fassarar asibiti, jagoranci da sabis ga al'ummar photonics (Lifetime Achievement Award), SPIE a Photonics West a San Francisco CA  
* 2018 Kyautar Kyautar Kyautattun Ayyuka don gudummawa mai mahimmanci a fagen binciken ciwon daji.  (Lifetime Achievement Award), Society of Asian American Scientists in Cancer Research Award for Contributions to Cancer Research (SAASCR), taron AACR a Chicago, IL 
* Kyautar 2017 don gagarumin ci gaba na Photodynamic Therapy, don ƙwarewar bincike a fagen photodynamic, Ƙungiyar Photodynamic ta Duniya a 16th IPA World Congress a Coimbra Portugal 
* 2015 Kyautar Rayuwa a cikin Binciken PDT, don Kwarewar Bincike a fagen Photodynamic Therapy, Ƙungiyar Photodynamic ta Duniya a Taron Duniya na 15 na IPA a Rio de Janeiro Brazil 
* 2014 Kyautar Daraktoci na Musamman don Sabis ga al'ummar HST, Harvard-MIT Division of Health Sciences & Technology (HST), Harvard Medical School 
* 2012 10th Anniversary Mentor Award, don nuna godiya ga jagorancin musamman na malaman postdoctoral da kuma jajircewa ga horar da masana kimiyya masu shirya sosai don nan gaba, Ƙungiyar Postdoctoral ta Kasa 
* 2010 Cibiyar Kimiyya don 'Yan Mata Catalyst Award girmamawa don sadaukarwa ga daidaito a Kimiyya, Injiniya da Fasaha 
* 2009 Makarantar Kiwon Lafiya ta Harvard William Silen Rayuwa a Kyautar Mentoring 
* 2009 Cibiyoyin Kiwon Lafiya na Kasa Pioneers a Biomedical Optics don Fassara daga Bench zuwa Bedside 
* 2007 Abokan hulɗa a Kyautar Kyauta, Abokan hulda Kiwon Lafiya (wanda yanzu ake kira Mass General Brigham) 
* 2001 Abokan hulɗa a Kyautar Kyauta, Abokan hulda Kiwon Lafiya (wanda yanzu ake kira Mass General Brigham) 
* 1968-70 National Merit Fellowships, Jami'ar Islamabad, Pakistan (wanda yanzu ake kira Jami'ar Quaid-i-Azam) 
* 1964-68 National Merit Scholarships, Hukumar Ilimi ta Punjab da Jami'ar Punjab, Pakistan 

## Manazarta