Wrinkling na nutsewar ruwa

wrinkle, wanda kuma aka sani da rhytid, ninki ne, tudu ko ƙugiya a cikin wani wuri mai santsi, kamar akan fata ko masana'anta.  Wrinkles fata yawanci suna fitowa ne sakamakon matakan tsufa kamar glycation,  matsayi na barci na al'ada,  asarar jiki, lalacewar rana,  ko na ɗan lokaci, sakamakon nutsewa cikin ruwa mai tsawo. Rashin tsufa a cikin fata yana ingantawa ta hanyar bayyanar fuska ta al'ada, tsufa, lalacewar rana, shan sigari, rashin ruwa, da sauran dalilai daban-daban. A cikin mutane, ana iya hana shi har zuwa wani mataki ta hanyar guje wa hasken rana da yawa da kuma ta hanyar abinci (musamman ta hanyar amfani da carotenoids, tocopherols da flavonoids, bitamin (A, C, D da E), mahimman omega-3-mai acid, wasu sunadarai da lactobacilli). 

## Fata
 

### Dalilan tsufa

Ci gaban gogewar fuska wani nau'i ne na Fibrosis na fata. Ka'idar tsufa ta lalacewar lalacewa ta nuna cewa wrinkles suna tasowa daga gyaran da ba daidai ba na fiber mai laushi da fiber na collagen. Sauye-sauye da matsawa na fata suna haifar da raunin da aka yi a cikin derma. A lokacin gyaran gyare-gyare, wasu daga cikin tsokoki masu laushi da tsokoki na collagen ba a sake farfadowa ba kuma an mayar da su amma an maye gurbinsu da tsokoshi masu canzawa. Lokacin da aka karya fiber mai laushi a cikin wani tsawo, ana iya maye gurbinsa da "tsawon" fiber collagen. Tattara "tsawon" fiber na collagen yana sa wani ɓangare na fata ya fi sauƙi kuma ya fi tsayi, kuma a sakamakon haka, babban fold na fata ya bayyana. Lokacin da aka karya "tsawon" collagen a cikin wani matsewa, ana iya maye gurbinsa da "gajeren" fiber collagen. Fiber collagen "gajere" zai ƙuntata fadada fiber "tsawon", kuma ya sa fiber "tsawo" a cikin yanayin ninkawa har abada. Ƙananan ninka, wato ƙuƙwalwa ta dindindin, sa'an nan kuma ya bayyana.

### Rashin bacci
Ana ƙirƙiri wrinkles na barci da ƙarfafa lokacin da aka matse fuska a kan matashin kai ko saman gado a gefe ko wuraren barci na ciki yayin barci. Suna bayyana a wurare masu hangowa saboda tsarin musculoaponeurotic (SMAS), kuma yawanci sun bambanta da wrinkles na fuska. Kamar yadda yake tare da wrinkles na fuska, barci wrinkles iya zurfafawa kuma ya zama na dindindin a tsawon lokaci, sai dai idan al'ada barci matsayi wanda ke haifar da wrinkels an canza.

### Rashin nutsewa na ruwa

Rashin da ke faruwa a cikin fata a kan dogon lokaci na ruwa ana kiransa yatsunsu ko tsufa na ruwa. Wannan Yanayin fata ne na wucin gadi inda fata a kan dabino na hannu ko ƙafafu ya zama mai laushi. Wannan amsawa mai laushi na iya ba da fa'idar juyin halitta ta hanyar samar da ingantaccen motsi a cikin yanayin rigar,  da kuma fahimtar abubuwa masu laushi.  Wadannan sakamakon sun kasance cikin tambaya ta hanyar binciken 2014 wanda ya kasa haifar da duk wani ci gaba na sarrafa abubuwa masu laushi tare da yatsunsu masu laushi. Koyaya, binciken da aka yi a shekarar 2020 game da yadda ya kamata ya gano cewa wrinkles sun rage ƙarfin da ake buƙata don riƙe abubuwa masu laushi da kashi 20%, suna tallafawa ra'ayin traction.

Kafin binciken na 1935, bayanin gama gari ya dogara ne akan shayar da ruwa a cikin fatar epithelial mai ɗauke da keratin lokacin da aka nutsar da shi cikin ruwa.,  wanda ke haifar da fata ya fadada kuma ya haifar da yanki mafi girma, yana tilasta shi ya yi wrinkle. Yawancin lokaci matakai na yatsunsu da yatsunsu sune na farko da za su yi wrinkle saboda wani nau'i mai kauri na keratin da rashin gashi wanda ke ɓoye mai kariya da ake kira sebum.

A cikin binciken 1935, duk da haka, Lewis da Pickering suna nazarin marasa lafiya tare da palsy na jijiyar tsakiya lokacin da suka gano cewa gogewar fata ba ta faru a yankunan fatar marasa lafiya da aka saba amfani da su ta hanyar jijiyar da ta lalace. Wannan ya ba da shawarar cewa tsarin juyayi yana taka muhimmiyar rawa a cikin wrinkling, don haka ba za a iya bayyana abin gaba ɗaya ba kawai ta hanyar shan ruwa. Binciken da aka yi kwanan nan ya nuna cewa wrinkling yana da alaƙa da vasoconstriction. Ruwa mai yiwuwa yana fara tsarin wrinkling ta hanyar canza ma'auni na electrolytes a cikin fata yayin da yake yadawa cikin hannaye da takalma ta hanyar hanyoyin gumi da yawa. Wannan na iya canza kwanciyar hankali na membranes na neurons da yawa waɗanda ke haɗuwa a kan jijiyoyin jini da yawa a ƙarƙashin fata, wanda ke sa su yi wuta da sauri. Ƙarin ƙarancin jijiyoyin jijiyoyi yana haifar da jijiyoyin jini su ƙuntata, rage yawan ruwa a ƙarƙashin fata. Wannan raguwar ruwa zai haifar da raguwar tashin hankali, wanda ke haifar da fata ya zama mai laushi.

Wannan fahimtar ta haifar da gwaje-gwaje na kusa da gado don lalacewar jijiyoyi da ƙuntatawar jini. Sau da yawa ana samun ƙwanƙwasawa tare da nutsewar hannayensu na minti 30 a cikin ruwa ko cream na EMLA tare da matakan ma'auni na minti 5, da ƙidaya yawan gogewa a lokaci. Ba duk mutanen da ke da lafiya ba ne suke da yatsa bayan nutsewa, don haka zai zama lafiya a ce ana kiyaye aikin tausayi idan an lura da yatsa ya nutsewa bayan nutsewar cikin ruwa, amma idan yatsunsu sun fito a hankali ba za a iya ɗauka cewa akwai rauni ga wadataccen kai  ga jijiyoyin hannu ba.

### Sauran dabbobi masu rufi
Ana iya samun misalan wrinkles a cikin nau'ikan dabbobi daban-daban waɗanda ke girma sako-sako da fata, musamman lokacin da suke kanana.  Kare da dama, irin su Pug da Shar Pei, an ƙirƙira su don wuce gona da iri.  A cikin karnuka da aka haifa don fada, wannan shine sakamakon zaɓi don fata maras kyau, wanda ke ba da fa'ida mai karewa.

### Dabarun don rage bayyanar wrinkles tsufa
iya

Shaidar yanzu ta nuna cewa Tretinoin yana rage haɗin gwiwar ƙwayoyin epithelial na follicular, kodayake ba a san ainihin yanayin aiki ba. Bugu da ƙari, tretinoin yana motsa aikin mitotic kuma yana ƙara juyawa na ƙwayoyin epithelial na follicular. Tretinoin an fi sani da sunan Retin-A .

Abubuwan kari na glycosaminoglycans na Topical na iya taimakawa wajen samar da maidowa na wucin gadi na ma'aunin enzyme don jinkiri ko hana rugujewar matrix da sakamakon farkon samuwar wrinkle.  Glycosaminoglycans (GAGs) jiki ne ke samarwa don kiyaye amincin tsari a cikin kyallen takarda da kuma kiyaye daidaiton ruwa.  Hyaluronic acid wani nau'i ne na GAG wanda ke inganta haɓakar collagen, gyara, da hydration.  GAGs suna aiki azaman mai damshi na halitta da mai mai tsakanin ƙwayoyin epidermal don hana samar da matrix metalloproteinases (MMPs).

Filayen fata sune samfuran allura da ake yawan amfani dasu don gyara wrinkles, da sauran baƙin ciki a cikin fata.  Sau da yawa wani nau'i ne na nama mai laushi da aka tsara don ba da damar allura a cikin fata don dalilai na inganta bayyanar.  Mafi yawan samfurori sun dogara ne akan hyaluronic acid da calcium hydroxylapatite.

Botulinum toxin furotin ne na neurotoxin wanda kwayar cuta *Clostridium botulinum* ta samar. Botox wani takamaiman nau'in guba ne na botulinum wanda Allergan ya ƙera don amfani da magani da kayan kwalliya. Baya ga aikace-aikacen kayan kwalliya, ana amfani da Botox a cikin maganin wasu yanayi ciki har da ciwon kai da ciwon mahaifa (spasmodic turticollis) (rashin lafiyar neuromuscular da ta shafi kai da wuyansa). 

Dysport, wanda Ipsen ya ƙera, ya sami amincewar FDA kuma yanzu ana amfani dashi don magance dystonia cervical da layin glabellar a cikin manya. A cikin shekara ta 2010, wani nau'in guba na botulinum, wanda ba shi da sunadarai masu rikitarwa, ya zama samuwa ga Amurkawa. Xeomin ya sami amincewar FDA don alamun kiwon lafiya a cikin 2010 da alamun kayan kwalliya a cikin 2011.

Botulinum toxin yana magance wrinkles ta hanyar dakatar da tsokoki wanda ke haifar da wrinkles. Ba ya dace da maganin dukkan wrinkles; an nuna shi don maganin layin glabellar (tsakanin gashin ido) a cikin manya. Duk wani amfani ba a amince da shi ta FDA ba kuma ana ɗaukarsa Amfani da lakabi.

Laser resurfacing is FDA-cleared skin resurfacing procedure in which lasers are used to improve the condition of the skin.&#x5B;**&#x5D; Two types of lasers are used to reduce the appearance of fine lines and wrinkles on the face; laser ablation, which removes thin layers of skin, and nonablative lasers that stimulate collagen production. Nonablative lasers are less effective than ablative ones but they are less invasive and  recovery time is short. After the procedure people experience temporary redness, itching and swelling.

## Dubi kuma

* Kwayar cutar Botulinum
* Abin da za a iya amfani da shi
* Cutar fata mai laushi

## Haɗin waje

* Tsufa a cikin Medline