Zena Werb

**Zena Werb** (24 Maris 1945 - 16 Yuni 2020) farfesa ce kuma Mataimakin Shugaban Anatomy a Jami'ar California, San Francisco . &nbsp;Ta kuma kasance co-shugaban Ciwon daji, rigakafi, da Shirin Microenvironment a Cibiyar Ciwon daji ta Hellen Diller Family kuma memba na Kwamitin Zartarwa na Cibiyar Bincike ta Sabre-Sandler Asthma a UCSF .  Binciken da ta yi ya mayar da hankali kan siffofin microenvironment da ke kewaye da sel, tare da sha'awa ta musamman ga matrix na extracellular da rawar da enzymes na protease ke takawa a cikin siginar sel.

## Rayuwa ta farko da ilimi
An haifi Zena Werb a Jamus a 1945 a sansanin Bergen-Belsen (KZ Bergen-B Nielsen), 'yan makonni kafin a saki sansanin. Iyayenta biyu, wadanda suka kasance 'yan Poland-Yahudawa, sun tsira daga yakin, tare da mahaifinta ya gudu zuwa Italiya. Iyalinta sun sake haduwa a sansanin 'yan gudun hijira a Italiya a 1947;  sun yi hijira zuwa Kanada a 1948, inda Werb ta girma a gona a Ontario.  Kodayake mahaifinta a baya masanin lissafi ne, ya zama manomi.

Werb ta sami B.Sc. a Biochemistry daga Jami'ar Toronto a shekarar 1966, bayan ta canza babban nata daga geophysics bayan an gaya mata cewa babu masauki ga mata a wani filin wasa. Ta sami Ph.D. a cikin Cell Biology daga Jami'ar Rockefeller a 1971, tana aiki a ƙarƙashin kulawar Zanvil Cohn a kan wata takarda mai taken "Dynamics of macrophage membrane cholesterol". Bayan kammala karatunta ta yi aiki a Cibiyar Nazarin Strangeways a Cambridge, Burtaniya a matsayin abokin karatun postdoctoral tare da John T. Dingle daga 1971 zuwa 1973 kuma a matsayin mai bincike daga 1973 zuwa 1975.   

## Ayyukan ilimi
Werb ta shafe shekara guda a matsayin mataimakiyar farfesa a makarantar likitancin Dartmouth a New Hampshire kafin ta koma Jami'ar California, San Francisco a 1976, inda ta zama cikakken farfesa a 1983.   Ta yi aiki a matsayin shugabar American Society for Cell Biology a shekara ta 2004. Ta yi magana game da darajar sabbatical na ilimi, kuma a cikin 2007 ta yi sabbatical a Cibiyar Max Planck ta hanyar Kyautar Bincike ta Alexander von Humboldt.

Werb ta rubuta kuma ta ba da tambayoyi game da abubuwan da ta samu a matsayin mace a kimiyya, tana kwatanta yanayin da ta horar da ita a matsayin mai nuna bambancin jinsi kuma tana lura da cewa, duk da ci gaban wakilcin mata a cikin kimiyya tun lokacin da ta horarwa, jima'i "ya tafi karkashin kasa"  kuma ƙarancin wakilcin mata masu matsayi na sama ya kasance matsala.

Ta kasance memba na Kwamitin Edita don Ci gaban Cell .

## Kyaututtuka da girmamawa

* Kyautar FASEB Excellence in Science daga Tarayyar Ƙungiyoyin Amirka don Nazarin Halitta (1966) 
* Guggenheim Fellowship (1985-6) 
* Ƙungiyar Amurka don Binciken Ciwon daji Mata a Binciken Cutar Charlotte Friend Memorial Lectureship (2001) 
* UCSF Kwalejin Bincike na Shekara (2001) 
* Fellow na Kwalejin Fasaha da Kimiyya ta Amurka (2003) 
* E.B. Wilson Medal daga American Society for Cell Biology (2007) 
* Kyautar Rayuwa ta Rayuwa daga Mata a cikin Kwayoyin Kwayoyin Kwayar halitta, ƙungiyar ASCB (2010) 
* memba na Kwalejin Kimiyya ta Kasa ta Amurka (2010) 
* Nasarar Rayuwa ta UCSF a Kyautar Jagora (2015) 

## Bincike
Kungiyar bincike ta Werb tana nazarin tasirin sel na microenvironment na matrix na extracellular da sassanta, musamman matrix metalloproteinases. Har ila yau, ƙungiyar tana bincika rawar da waɗannan tasirin ke takawa a kan matakai na halitta kamar su tsufa da ƙwayoyin cuta, wanda suke amfani da ciwon nono a cikin beraye a matsayin abin koyi. Ayyukanta na kafa rawar da ECM ke takawa a cikin siginar tantanin halitta na yau da kullun da kuma ci gaban ciwon daji an san shi da tasiri sosai.

## Manazarta

## Haɗin waje

* PubMed/?term=Werb+Z%5BAuthor%5D&cauthor=true&cauthor_uid=26155427" id="mwAhY" rel="mw:ExtLink nofollow">Takardun da ke kan PubMed
* Fiona M. Watt, "Zena Werb", Tarihin Rayuwa na Kwalejin Kimiyya ta Kasa (2021)