Brigid Hogan

**Brigid L. M. Hogan** FRS masanin kimiyyar halittu ne na ci gaban Burtaniya wanda aka sani da gudummawar da ta bayar ga ci gaban dabbobi masu shayarwa, binciken tantanin halitta da fasahar transgenic da dabarun. A halin yanzu Farfesa ce a Sashen Kwayar halitta a Jami'ar Duke,   An haife ta a Burtaniya, ta zama 'yar ƙasar Amurka a shekara ta 2000.

Hogan ta sami digirinta na PhD a fannin ilmin sunadarai a Jami'ar Cambridge kuma ta yi aiki na postdoctoral a Sashen ilmin halitta a MIT. Ta kasance shugabar Laboratory of Molecular Embryology a Cibiyar Nazarin Kiwon Lafiya ta Kasa a London, kuma daga baya Farfesa Hortense B. Ingram a Sashen Kwayar halitta kuma darektan kafa Shirin Stem Cell da Organogenesis a Jami'ar Vanderbilt.  A shekara ta 2002, ta koma Jami'ar Duke.

Ayyukanta a kan ci gaban linzamin kwamfuta ya kai ta ga shirya karatun farko na Molecular Embryology of the Mouse a Cold Spring Harbor Laboratory da kuma gyara bugu biyu na farko na Manipulating the Mouse Embryo: A Laboratory Manual, wanda aka yi la'akari da "Bible" na dabarun sarrafa embryo na dabbobi masu shayarwa.

Ta yi aiki a matsayin shugabar American Society for Developmental Biology da American Society for Cell Biology . Ta kasance memba na Majalisar Ba da Shawara ta Kasa ta Cibiyar Kula da Lafiya ta Yara da Ci gaban Dan Adam ta Kasa, Co-Chairman Kimiyya na Kwamitin Binciken Ɗalilo na NIH na 1994 kuma memba na Kwamitin Kwalejin Kwalejin Kasa na 2001/2002 kan fannonin Kimiyya da Kiwon Lafiya na Cloning na Mutum. An ba ta lambar yabo ta shida ta International Society for Transgenic Technologies a shekarar 2008 don "babban gudummawa ga fannin fasahar transgene". Ta gabatar da jawabin Martin Rodbell na 2011, wanda Cibiyar Kimiyya ta Kiwon Lafiya ta Kasa ta shirya  da kuma jawabin Croonian na Royal Society na London a cikin 2014.

## Rayuwa ta farko
An haifi Hogan a Denham, wani karamin ƙauye kusa da London. Iyayenta biyu masu zane-zane ne. Yayinda take yarinya ta fuskanci matsalolin Burtaniya bayan yakin duniya na biyu . Mahaifinta, mai tsara wasan kwaikwayo, ya mutu a 1945 jim kadan bayan ya dawo daga layin gaba. Mahaifiyarta mai zaman kanta, mai yin tufafi, ta tayar da ita da 'yar'uwarta. Ta kasance goyon baya da wahayi ga Hogan. Garin da Hogan ya girma a ciki yana kusa da yanayi kuma ya inganta ƙaunarta ga ilmin halitta. Tunaninta na kimiyya ya taimaka mata ta jimre da rayuwar gidanta mara tabbas. Ta halarci Makarantar Sakandare ta Wycombe don 'yan mata, inda malaminta na ilmin halitta ya jagoranci ta yayin da ta nemi Jami'ar Cambridge. An shigar da ita a Kwalejin Newnham, kwalejin mata na Cambridge, inda ta fuskanci mummunan hali daga ma'aikatan maza saboda jinsi, wanda ya dace da lokacin.

## Ayyuka
Tun da Cambridge ba ta ba da darussan a cikin tantanin halitta ko ilmin halitta na ci gaba a lokacin ba, Hogan ta yi aikinta na post-doctorate a kan ci gaban urchin na teku tare da Paul Gross a MIT. A kusa da shekara ta 1974, a Burtaniya, Hogan ta fara aikinta a kan kwayoyin ƙwayar ƙwayar ƙwaƙwalwa a Mill Hill Labs na Asusun Binciken Ciwon daji na Imperial a London a karkashin darektan John Cairns. Anne McLaren ta karfafa ta, ta mayar da hankali ga aikinta kan ci gaban linzamin kwamfuta kuma ta ci gaba da wannan hanyar tun daga lokacin. Ta kasance shugabar Laboratory of Molecular Embryology a Asusun Binciken Ciwon daji na Imperial sannan kuma Cibiyar Nazarin Kiwon Lafiya ta Kasa a London. Ɗalibinta, Peter Holland, ya zama sananne sosai saboda aikinsa a kan juyin halitta kuma an ba shi lambar yabo ta Darwin na Royal Society a cikin 2019.

A shekara ta 1988, Hal Moses ya dauke ta zuwa Cibiyar Kiwon Lafiya ta Jami'ar Vanderbilt. A can ta kasance Farfesa a fannin ilmin halitta da Hortense B. Ingram Chair of Molecular Oncology, da kuma co-kafa Shirin Stem Cell da Organogenesis .  Daga 1993 zuwa 2002, ta kasance mai bincike na Cibiyar Kiwon Lafiya ta Howard Hughes . A Jami'ar Vanderbilt, ta girma don godiya ga sha'awar Amurka game da nazarin kimiyya gabaɗaya da kuma mata a fagen kimiyya musamman. Ta dauki aikinta a Vanderbilt "ɗaya daga cikin mafi yawan aiki da ban sha'awa" a cikin aikinta. Ta bar Vanderbilt a shekara ta 2002 bayan shekaru 13 don jagorantar sashen Cell Biology a Cibiyar Kiwon Lafiya ta Jami'ar Duke, wanda ya sa ta zama mace ta farko da ta jagoranci sashen kimiyyar asali a can.

A Jami'ar Duke, ta kasance George Barth Geller Farfesa na Molecular Biology daga 2002-2018 kafin ta sauka a matsayin Shugaban a shekarar 2019. Ta ci gaba da tsara rawar da take takawa a Sashen Biology na Cell da kuma shirin horar da Ci gaba da Stem Cell. Labinta ya yi nazarin huhu, saboda yana tasowa ta hanyar "morphogenesis reshe". Don sauƙaƙe wannan, ta kirkiro layin linzamin kwamfuta da yawa inda za'a iya sarrafa kwayoyin halitta a cikin takamaiman sel na huhu. Tana da sha'awar ƙwayoyin ƙwayar ƙwayar ƙwaƙwalwar ƙwayar ƙwaya a matsayin samfuran ƙwayoyin huhu na ɗan adam waɗanda ke fama da cuta sau da yawa.[1] Tana fatan yin amfani da bincikenta ga cututtukan huhu na yau da kullun, Cystic fibrosis, asma na yau da kullum, Fibrosis na huhu, da jarirai da ba su da isasshen ci gaban huhu.[2]

## Kyaututtuka da karbuwa

* 1986 - memba na Ƙungiyar Kwayoyin Kwayoyin Turai 
* 1993-2002 - Mai bincike na Cibiyar Kiwon Lafiya ta Howard Hughes 
* 1996 - memba na Cibiyar Kiwon Lafiya 
* 2001 - Fellow na Royal Society 
* 2001 - Shugaban American Society for Developmental Biology 
* 2001 - American Academy of Arts and Sciences Fellow 
* 2003 - Ƙungiyar Amurka don Ci gaban Kimiyya 
* 2005 - memba na Kwalejin Kimiyya ta Kasa 
* 2008 - Kyautar Ƙungiyar Duniya don Fasahar Transgenic 
* 2009 - Shugaban American Society for Cell Biology 
* 2014 - Karatun Croonian 
* 2015 - Kyautar Rayuwa ta Rayuwa, Society for Developmental Biology
* 2019 - Alumni na Makarantar Kiwon Lafiya ta Jami'ar Duke 2019 Kyautar Rayuwa
* 2019 - Kyautar Kyautar FASEB a Kimiyya

## Manazarta