Dupuytren's contracture

**Dupuytren's contracture** (dem sanso call **Dupuytren's disease**, **Morbus Dupuytren**, **Palmar fibromatosis** den historically as **Viking disease** anaa **Celtic hand**) be a condition insyd wich one anaa more fingers cam permanently be bent insyd a flexed position. Dem name am after Guillaume Dupuytren, wey na first describe de underlying mechanism of action, wey be followed by de first successful operation insyd 1831 den publication of de results insyd *The Lancet* insyd 1834. E usually dey begin as small, hard nodules just under de skin of de palm, then dey worsen over time til de fingers no longer fi be fully straightened. While typically no be painful, sam aching anaa itching, anaa pain, fi be present. De ring finger follow by de little and middle fingers be most commonly affected. E fi affect one anaa both hands. De condition fi interfere plus activities such as preparing chow, writing, putting de hand insyd a tight pocket, putting on gloves, anaa shaking hands.

Der be no single cause for Dupuytren's contracture, buh der be chaw risk factors wey be associated plus an increased risk of developing am. De cause be unknown buh fi get a genetic component. Risk factors dey include family history, alcoholism, smoking, thyroid problems, liver disease, diabetes, previous hand trauma, den epilepsy. De underlying mechanism dey involve de formation of abnormal connective tissue within de palmar fascia. Diagnosis usually dey base on physical examination. Insyd sam cases imaging fi be indicated.

Insyd 2020, na de World Health Organization reclassify Dupuytren's (dem term palmar-type fibromatosis) as a specific type of tumor insyd de category of intermediate (locally aggressive) fibroblastic den myofibroblastic tumors.

Initial treatment be typically plus cortisone dem inject into de affected area, occupational therapy, den physical therapy. Among those wey worsen, clostridial collagenase injections anaa surgery fi be tried. Radiation therapy fi be used to treat dis condition. Na de Royal College of Radiologists (RCR) Faculty of Clinical Oncology conclude say radiotherapy be effective insyd early stage disease wich na progress within de last 6 to 12 months. De condition fi recur at sam time after treatment; e then sanso fi be treated. E be easier to treat wen de amount of finger bending be more mild.

Na dem once believe say Dupuytren's most often occur insyd white males over de age of 50 wey na dem think to be rare among Asians den Africans. E sam times be called "Viking disease," since na e often be recorded among those of Nordic descent. Insyd Norway, na about 30% of men over 60 years old get de condition, while insyd de United States about 5% of people be affected at sam point insyd time. Insyd de United Kingdom, na about 20% of people over 65 get sam form of de disease.

More recent den wider studies dey show de highest prevalence insyd Africa (17 percent) den Asia (15 percent).

## Notable cases
* Chelsea Handler (born 1975), American comedian, actress den writer
* Tim Herron (born 1970), American golfer
* Prince Joachim of Denmark (born 1969)
* Joanne Harris (born 1964), British author
* Tommy Lee (born 1962), American drummer
* Ally McCoist (born 1962), Scottish footballer
* Jonathan Agnew (born 1960), English cricketer
* John Elway (born 1960), American football player
* Nanci Griffith (1953–2021),  American singer, guitarist, den songwriter
* Bill Murray (born 1950), American actor den comedian
* Bill Nighy (born 1949), British actor
* Mitt Romney (born 1947), American politician
* Misha Dichter (born 1945), American pianist
* José Feliciano (born 1945), Puerto Rican musician, singer den composer
* Bill Frindall (1939–2009), English cricket player den statistician, wey na dem amputate a finger
* David McCallum (1933–2023), Scottish/British actor den musician
* Paul Newman (1925–2008), American actor den film director
* Margaret Thatcher (1925–2013), Prime Minister of de United Kingdom
* Ronald Reagan (1911–2004), American President den actor
* Andrew Wyeth (1917–2009), American visual artist
* Frank Sinatra (1915–1998), American singer, actor, den producer
* Samuel Beckett (1906–1989), Irish novelist, poet and playwright
* Max Planck (1858–1947), German theoretical physicist den Nobel Prize laureate
* Dave Mustaine (born 1961), American guitarist

## References


## External links