TACC2

**Protein 2 sa transformirajućom kiselom upredenom zavojnicom** je  protein  koji je kod ljudi kodiran genom **TACC2**.

1020304050
MGNENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSI
GSVGLGGFCTASESSASLDPCLVSPEVTEPRKDPQGARGPEGSLLPSPPP
SQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPGDI
AAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGM
SPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTP
EAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYL
TDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGL
PSPALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGG
LPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGM
PVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEH
LNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPT
DGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQ
AFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQ
TAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQPKCPDT
LQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGSC
DGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQGENLAADLGLTALILDQ
DQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQ
PPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSE
LQSQLPKGTLSDTPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKRPE
GACGDGQSSRVSPPAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADA
LEEGSQHEEACQRHPGASEAADGCSPLWGLSKREMASGNTGEAPPCQPDS
VALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQQKM
ECWATSDAESPKLLASFPSAGEQGGEAGAAETGGSAGAGDPGKQQAPEKP
GEATLSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASCQDALLPAREL
GGIPRSTMDFSTHQAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAED
SGVKAVSSADPRAPGESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAA
GGEIPAVQASSGSPKARTTEGPVDSMPCLDRMPLLAKGKQATGEEKAATA
PGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQGTSGGVDTSSEQIA
TLTGFPDFREHIAKIFEKPVLGALATPGEKAGAGRSAVGKDLTRPLGPEK
LLDGPPGVDVTLLPAPPARLQVEKKQQLAGEAEISHLALQDPASDKLLGP
AGLTWERNLPGAGVGKEMAGVPPTLREDERPEGPGAAWPGLEGQAYSQLE
RSRQELASGLPSPAATQELPVERAAAFQVAPHSHGEEAVAQDRIPSGKQH
QETSACDSPHGEDGPGDFAHTGVPGHVPRSTCAPSPQREVLTVPEANSEP
WTLDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGEVADTPLEPGKVAG
AAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPA
CSDKAPGMEGTAALHGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPPEP
DETHDPKLQHLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTSDET
RGAEGTESSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQS
ISPAAAHAGLPPSAAEHIVSPSAPAGDRVEASTPSCPDPAKDLSRSSDSE
EAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVP
DGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQ
TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSS
GNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPV
KETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPK
AACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDS
GGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLR
RPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPF
SSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEI
PASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDP
TPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSD
LSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLM
FDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLA
PNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLA
HPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIAL
ASRSHQDAKREAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSA
LQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDE
QREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFR
KNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQ
QEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS

## Funkcija 
Proteini transformirajuće kisela upredene zavojnice su iz porodice konzerviranih sekvenci centrosoma –   mikrotubula –interaktivni proteini koji su uključeni u kancere. Ovaj gen kodira protein koji se tokom ćelijskog ciklusa koncentrira u centrosomima. Ovaj gen leži unutar hromozomke regije povezane sa tumorigenezom. Smatra se da ekspresija ovog gena utiče na progresiju tumora dojke . Ekspresiju ovog gena također inducira eritropoetin.

## Reference
## Dopunska literatura
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Kategorija:Geni na hromosomu 10
Kategorija:Ljudski proteini
Kategorija:Proteomika