NBEAL2

**Neurobeahinoliki protein  2** jest protein koji je kod ljudi kodiran genom **NBEAL2** sa hromosoma 3.

## Aminokiselinska sekvenca
Dužina polipeptidnog lanca je 2 754 aminokiseline, а molekulska težina  302.517 Da..

1020304050
MAASERLYELWLLYYAQKDLGYLQQWLKAFVGAFKKSISLSSLEPRRPEE
AGAEVPLLPLDELHVLAEQLHQADLEQALLLLKLFIILCRNLENIEAGRG
QVLVPRVLALLTKLVAELKGCPPPQGRGTQLENVALHALLLCEGLFDPYQ
TWRRQRSGEVISSKEKSKYKFPPAALPQEFSAFFQESLQNADHLPPILLL
RLIHLFCAVLAGGKENGQMAVSDGSVKGLLSVVRGWSRGPAPDPCLVPLA
LEALVGAVHVLHASRAPPRGPELRALLESYFHVLNADWPAGLSSGPEEAL
VTLRVSMLDAIPMMLACEDRPVLQATFLSNNCFEHLTRLIQNSKLYLQSR
APPEGDSDLATRLLTEPDVQKVLDQDTDAIAVHVVRVLTCIMSDSPSAKE
VFKERIGYPHLQEVLQSHGPPTHRLLQELLNMAVEGDHSMCPPPPIRNEQ
PVLVLAQWLPSLPTAELRLFLAQRLRWLCDSCPASRATCVQAGLVGCLLE
TLSTGLALEARCQEQLLALLQALGRVSIRPMELRHLLRPRPGLDSEPGGA
EAGKARHAGAVIRTLSGMARHQGPARALRYFDLTPSMAGIMVPPVQRWPG
PGFTFHAWLCLHPMDTAPTPAPTRPLQRKQLYSFFTSSGSGFEAFFTAAG
TLVVAVCTRKEYLTMSLPEVSFADSAWHCVAIVHVPGRRPFSQNLVHVYK
DGHLVKTAPLRCPSLSEPFSSCCIGSAGYRTTTTTTGLPTPPVPATLAYT
HPALTRSQSVPASTGLGWGSGLVAPLQEGSIDSTLAGTQDTRWGSPTSLE
GELGAVAIFHEALQATALRTLCTLGPNETAPFKPEGELHELSTRLLLHYS
PQACKNNICLDLSPSHGLDGRLTGHRVETWDVKDVVNCVGGMGALLPLLE
RVAAQPKEAEAGPAETHDLVGPELTSGHNTQGLVLPLGKSSEERMERNAV
AAFLLMLRNFLQGHMVNQESLVQCQGPAIIGALLRKVPSWAMDMNVLMSA
QLLMEQVAAEGSGPLLYLLYQHLLFNFHLWTLSDFAVRLGHIQYMSSIVR
EHRQKLRKKYGVQFILDALRTHYSPQRERPLAADDLRTVQTSLLGLAREF
LVRSLSADDVQVTQTMLSFLAATGDDGQAVGALDLLLALLHGSLVQESLA
VFLLEPGNLEVLLALLVRPGSLPLLPDRVCKILRRLQQNERLPERSRQRL
RLRECGLQGLVACLPEGTVSPQLCQGLYKLFLGADCLNLSDLLAVVQLSL
QADLSVRLDICRQLFHLIYGQPDVVRLLARQAGWQDVLTRLYVLEAATAG
SPPPSSPESPTSPKPAPPKPPTESPAEPSDVFLPSEAPCPDPDGFYHALS
PFCTPFDLGLERSSVGSGNTAGGGGSSGTLTPASQPGTPSPLDGPRPFPA
APGRHSSSLSNVLEDGSLPEPTISGDDTSNTSNPQQTSEEELCNLLTNVL
FSVTWRGVEGSDEAAWRERGQVFSVLTQLGASATLVRPPDCIKRSLLEMM
LESALTDIKEAPVGVLASLTQQALWLLRLLQDFLCAEGHGNQELWSEKLF
EGVCSLLDRLGAWPHLANGTADLREMAQIGLRLVLGYILLEDPQLHAQAY
VRLHMLLQTAVPARREEACYVLSKLEAALGRVLNTSSLESATDEAGSPLA
AAAAAAAAERCSWLVPLVRTLLDRAYEPLGLQWGLPSLPPTNGSPTFFED
FQAFCATPEWRHFIDKQVQPTMSQFEMDTYAKSHDLMSGFWNACYDMLMS
SGQRRQWERAQSRRAFQELVLEPAQRRARLEGLRYTAVLKQQATQHSMAL
LHWGALWRQLASPCGAWALRDTPIPRWKLSSAETYSRMRLKLVPNHHFDP
HLEASALRDNLGEVPLTPTEEASLPLAVTKEAKVSTPPELLQEDQLGEDE
LAELETPMEAAELDEQREKLVLSAECQLVTVVAVVPGLLEVTTQNVYFYD
GSTERVETEEGIGYDFRRPLAQLREVHLRRFNLRRSALELFFIDQANYFL
NFPCKVGTTPVSSPSQTPRPQPGPIPPHTQVRNQVYSWLLRLRPPSQGYL
SSRSPQEMLRASGLTQKWVQREISNFEYLMQLNTIAGRTYNDLSQYPVFP
WVLQDYVSPTLDLSNPAVFRDLSKPIGVVNPKHAQLVREKYESFEDPAGT
IDKFHYGTHYSNAAGVMHYLIRVEPFTSLHVQLQSGRFDCSDRQFHSVAA
AWQARLESPADVKELIPEFFYFPDFLENQNGFDLGCLQLTNEKVGDVVLP
PWASSPEDFIQQHRQALESEYVSAHLHEWIDLIFGYKQRGPAAEEALNVF
YYCTYEGAVDLDHVTDERERKALEGIISNFGQTPCQLLKEPHPTRLSAEE
AAHRLARLDTNSPSIFQHLDELKAFFAEVVSDGVPLVLALVPHRQPHSFI
TQGSPDLLVTVSASGLLGTHSWLPYDRNISNYFSFSKDPTMGSHKTQRLL
SGPWVPGSGVSGQALAVAPDGKLLFSGGHWDGSLRVTALPRGKLLSQLSC
HLDVVTCLALDTCGIYLISGSRDTTCMVWRLLHQGGLSVGLAPKPVQVLY
GHGAAVSCVAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRPLGATFPG
PIFHLALGSEGQIVVQSSAWERPGAQVTYSLHLYSVNGKLRASLPLAEQP
TALTVTEDFVLLGTAQCALHILQLNTLLPAAPPLPMKVAIRSVAVTKERS
HVLVGLEDGKLIVVVAGQPSEVRSSQFARKLWRSSRRISQVSSGETEYNP
TEAR

## Funkcija 
Protein kodiran ovim genom sadrži bež i Chediak-Higashijev (BEACH) domen i više WD40 domena, a može imati ulogu u biogenezi megakariocita alfa-granula.

## Reference
## Further reading 
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Kategorija:Geni na hromosomu 3
Kategorija:Ljudski proteini
Kategorija:Proteomika