SRCAP

**Helikaza SRCAP** je enzim koji je kod ljudi kodiran genom **SRCAP**.

Pomoći radiajacijske hibridne analize, Nagase et al. (1997) mapirali su  gen SRCAP na  hromosomu 16.

## Aminokiselinska sekvenca
Dužina polipeptidnog lanca je  3.230  aminokiselina, a molekulska težina   343.555 Da..

1020304050
MQSSPSPAHPQLPVLQTQMVSDGMTGSNPVSPASSSSPASSGAGGISPQH
IAQDSSLDGPPGPPDGATVPLEGFSLSQAADLANKGPKWEKSHAEIAEQA
KHEAEIETRIAELRKEGFWSLKRLPKVPEPPRPKGHWDYLCEEMQWLSAD
FAQERRWKRGVARKVVRMVIRHHEEQRQKEERARREEQAKLRRIASTMAK
DVRQFWSNVEKVVQFKQQSRLEEKRKKALDLHLDFIVGQTEKYSDLLSQS
LNQPLTSSKAGSSPCLGSSSAASSPPPPASRLDDEDGDFQPQEDEEEDDE
ETIEVEEQQEGNDAEAQRREIELLRREGELPLEELLRSLPPQLLEGPSSP
SQTPSSHDSDTRDGPEEGAEEEPPQVLEIKPPPSAVTQRNKQPWHPDEDD
EEFTANEEEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELSMEELLQQ
YAGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSV
EDRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQADEEEEDDDFG
VEYLLARDEEQSEADAGSGPPTPGPTTLGPKKEITDIAAAAESLQPKGYT
LATTQVKTPIPLLLRGQLREYQHIGLDWLVTMYEKKLNGILADEMGLGKT
IQTISLLAHLACEKGNWGPHLIIVPTSVMLNWEMELKRWCPSFKILTYYG
AQKERKLKRQGWTKPNAFHVCITSYKLVLQDHQAFRRKNWRYLILDEAQN
IKNFKSQRWQSLLNFNSQRRLLLTGTPLQNSLMELWSLMHFLMPHVFQSH
REFKEWFSNPLTGMIEGSQEYNEGLVKRLHKVLRPFLLRRVKVDVEKQMP
KKYEHVIRCRLSKRQRCLYDDFMAQTTTKETLATGHFMSVINILMQLRKV
CNHPNLFDPRPVTSPFITPGICFSTASLVLRATDVHPLQRIDMGRFDLIG
LEGRVSRYEADTFLPRHRLSRRVLLEVATAPDPPPRPKPVKMKVNRMLQP
VPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLM
VSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPP
TPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTT
TATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVAN
AGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHL
ISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPP
TMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTP
GRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSP
LHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAP
ASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASP
SASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLV
PASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAP
SPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPA
PTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTL
SLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAP
APPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGP
AAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDT
LTLRSGPPSPPSTATSFGGPRPRRQPPPPPRSPFYLDSLEEKRKRQRSER
LERIFQLSEAHGALAPVYGTEVLDFCTLPQPVASPIGPRSPGPSHPTFWT
YTEAAHRAVLFPQQRLDQLSEIIERFIFVMPPVEAPPPSLHACHPPPWLA
PRQAAFQEQLASELWPRARPLHRIVCNMRTQFPDLRLIQYDCGKLQTLAV
LLRQLKAEGHRVLIFTQMTRMLDVLEQFLTYHGHLYLRLDGSTRVEQRQA
LMERFNADKRIFCFILSTRSGGVGVNLTGADTVVFYDSDWNPTMDAQAQD
RCHRIGQTRDVHIYRLISERTVEENILKKANQKRMLGDMAIEGGNFTTAY
FKQQTIRELFDMPLEEPSSSSVPSAPEEEEETVASKQTHILEQALCRAED
EEDIRAATQAKAEQVAELAEFNENDGFPAGEGEEAGRPGAEDEEMSRAEQ
EIAALVEQLTPIERYAMKFLEASLEEVSREELKQAEEQVEAARKDLDQAK
EEVFRLPQEEEEGPGAGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLR
GARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASA
PAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACT
PPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPE
AELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNL
SLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESN
GLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAA
PSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKL
PGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPE
SSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGALLA
ITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPET
LIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPI
PGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTIST
SPPKRKRGRPPKNPPSPRPSQLPVLDRDSTSVLESCGLGRRRQPQGQGES
EGSSSDEDGSRPLTRLARLRLEAEGMRGRKSGGSMVVAVIQDDLDLADSG
PGGLELTPPVVSLTPKLRSTRLRPGSLVPPLETEKLPRKRAGAPVGGSPG
LAKRGRLQPPSPLGPEGSVEESEAEASGEEEEGDGTPRRRPGPRRLVGTT
NQGDQRILRSSAPPSLAGPAVSHRGRKAKT

:Simboli

**C**:  Cistein 
**D**: Asparaginska kiselina 
**E**: Glutaminska kiselina 
**F**:  Fenilalanin 
**G**:  Glicin 
**H**:  Histidin 
**I**:  Izoleucin 
**K**: Lizin 
**L**: Leucin 
**M**:  Metionin 
**N**:  Asparagin 
**P**:  Prolin 
**Q**:  Glutamin 
**R**:  Arginin 
**S**:  Serin 
**T**:  Treonin 
**V**:  Valin 
**W**:  Triptofan 
**Y**:  Tirozin

## Reference
## Dopunska literatura
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## Vanjski linkovi
* [OMIM entry on Floating-Harbor syndrome and SRCAP](http://www.omim.org/search?index=entry&start=1&limit=10&sort=score+desc&search=number:(136140+OR+611421))

Kategorija:Geni na hromosomu 16
Kategorija:Ljudski proteini
Kategorija:Proteomika