Title: Genomics of pattern recognition receptors
Description: This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.--
Subjects: Cell receptors, Genetics, Genomic Structural Variation, Pattern Recognition Receptors, Cardiovascular Diseases, Neoplasms, Genetik, Kardiovaskuläre Krankheit, Genomik, Humangenetik, Onkologie, Immunology, Cancer, research, Human genetics