Title: Reactions of Diketones and N-Allenoyloxazolidinones Catalyzed by Metal-Bis(oxazoline) Complexes
Description: This dissertation describes the investigation of the utility of metal-bis(oxazoline) complexes in catalytic asymmetric reactions. The development of Cu(II)-catalyzed regio- and enantioselective additions of silylketenthioacetals into diketones is discussed in the first chapter. Cu(OTf)2(t-BuBox) complexes were found to be an effective catalyst with a broad substrate scope, providing tertiary alcohols in high yields, regioselectivities, and enantioselectivities. A model that accounts for the absolute stereochemistry of the product based on A1,3-interaction was proposed. Relative reactivities among diketones were also investigated.