Title: Role of Capsaicin in Oxidative Stress and Cancer
Description: This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival p
Subjects: Capsaicin, Oncology, MEDICAL / Oncology, HEALTH & FITNESS / Diseases / Cancer, Physiology, Neoplasms, Nutritional Physiological Phenomena, Cancer, Nutritional aspects, Physiological effect