Title: Handbook of adaptive designs in pharmaceutical and clinical development
Description: "This comprehensive guide offers a unified presentation of the principles and methodologies in adaptive design and analysis. It gives a well-balanced summary of current regulatory perspectives and recently developed statistical methods in this area. The handbook provides some insight regarding early phase and later phase adaptive designs. With a focus on the implementation of adaptive methods in clinical trials, it introduces the concepts of role, responsibility, function, and activity of a data safety monitoring board (DSMB) when applying these methods. Other important topics covered in detail include regulatory perspectives and logistics issues in applying adaptive design methods"--Provided by publisher.
Subjects: Research Design, Clinical trials, Drugs, Handbooks, manuals, Clinical Trials as Topic, Statistics as Topic, Methodology, Research, Methods, Drugs, design, Sampling (statistics), HEALTH & FITNESS, Alternative Therapies, MEDICAL, Healing, BODY, MIND & SPIRIT, General