Title: Immunobiology of bacterial CpG-DNA
Description: Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages & dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules & pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book is the first comprehensive review of the data emerging in this field.
Subjects: Immuno competent cells, Antigen-Presenting Cells, Immunology, Cellular immunity, CpG Islands, T cells, DNA Vaccines, Antigen presenting cells, Immunologic Adjuvants, Immune response, Bacterial DNA, Immunocompetent cells