Title: Indoles (Best Synthetic Methods)
First published: July 2, 1996
Description: Indoles continue to be of great interest to the pharmaceutical industry and at the current time several thousand specific new derivatives are reported annually. Research has been driven by the wide range of indole derivatives which occur in nature and by the biological activity of many indole derivatives, of both natural and synthetic origin.

This book provides a systematic guide to the most useful and important reactions in the field for both synthesis and synthetic modification of the indole ring. While including the most recently developed and promising methods, it also updates information available on classical methods to give the reader an up-to-date and comprehensive view of the subject.

The methods are illustrated by procedures drawn from the literature and by tables including examples chosen to indicate both the scope of applicability and variations in methodology. The organisation of the book is based on the retrosynthetic concept of identifying the bond(s) formed in the reaction, which in turn identifies potential starting materials.
Subjects: Indole, Synthesis