Title: Botulinum Neurotoxins
Description: The extremely potent substance botulinum neurotoxin (BoNT) has attracted much interest in diverse fields. Originally identified as cause for the rare but deadly disease botulism, military and terrorist intended to misuse this sophisticated molecule as biological weapon. This caused its classification as select agent category A by the Centers for Diseases Control and Prevention and the listing in the Biological and Toxin Weapons Convention. Later, the civilian use of BoNT as long acting peripheral muscle relaxant has turned this molecule into an indispensable pharmaceutical world wide with annual revenues >$1.5 billion--
Subjects: Neurotoxic agents, Botulinum toxin, Botulinum toxin, therapeutic use, Therapeutic use, Type A Botulinum Toxins, Pharmacology, Neuromuscular Agents, Botulinum toxin -- Therapeutic use, Botulinum Toxins -- therapeutic use, Toxines botuliniques, Emploi en thérapeutique