Computational systems biology
By: edited by Andres Kriete, Roland Eils
Contributors: Kriete, Andres; Eils, Roland
Publisher: Elsevier Academic Press
Published: 2006
Place of publication: Burlington, MA
Language: eng
Number of pages: 409
Subjects: Biological systems -- Computer simulation
Description: Computational systems biology is a field that aims to develop a systems level understanding of biological processes using computational techniques. This book presents a compendium of the state-of-the-art in this new era of biological understanding. The contributors review bioinformation engineering and data integration technologies along with biomedical applications. Different computational approaches to model and simulate biological systems are discussed. Current computational research efforts, comprehensively covered in this volume, are focused on regulatory, signaling and metabolic networks. New concepts for computer representations on multi-scales predicting emergent properties of biological systems are introduced.
Notes: Includes bibliographical references and index
Table of contents: title: Introducing computational systems biology / Andres Kriete and Roland Eils; title: Enabling information and integration technologies for systems biology. Databases for systems biology / Jürgen Eils ... [et al.]; title: Natural language processing and ontology-enhanced biomedical literature mining for systems biology / Xiaohua Hu; title: Integrated imaging informatics / Barham Parvin ... [et al.]; title: Simpathica : a computational systems biology tool within the valis bioinformatics environment / Bud mishra ... [et al.]; title: Standards, platforms, and applications / Herbert M. Sauro; title: Foundations of biochemical network analysis and modeling. Introduction to computational models of biochemical reaction networks / F.J. Bruggeman ... [et al.]; title: Biological foundations of signal transduction and the systems biology perspective / Ursula Klingmüller; title: Reconstruction of metabolic network from genome information and its structural and functional analysis / Hong-Wu Ma and An-Ping Zeng; title: Integrated regulatory and metabolic models / Markus W. Covert; title: Computer simulations of dynamic networks. A discrete approach to network modeling / Reinhard Laubenbacher and Pedro Mendes; title: Gene networks : estimation, modeling and simulation / Seiya Imoto, Hiroshi Matsuno, and Satoru Miyano; title: Computational models for circadian rhythms : deterministic versus stochastic approaches / Jean-Christophe Leloup, Didier Gonze, and Albert Goldbeter; title: Multi-scale representations of cells and emerging phenotypes. Multistability and multicellularity : cell fates as high-dimensional attractors of gene regulatory networks / Sui Huang; title: Spatio-temporal systems biology / Avijit ghosh ... [et al.]; title: Cytomics; title: from cell states to predictive medicine / Günter Valet ... [et al.]; title: The IUPS Physiome Project : progress and plans / Peter Hunter ... [et al.]