Drug Metabolism and Transport
Subtitle: Molecular Methods and Mechanisms (Methods in Pharmacology and Toxicology)
Edition: 1 edition
Publisher: Humana Press
Published: September 24, 2004
Language: eng
Format: Hardcover
Number of pages: 400
ISBN-13: 9781588293244
Subjects: Pharmacology; Medical / Nursing; Medical; Toxicology; Physiological transport; Medical / Pharmacy; Drug Guides; Reference; Drugs; Metabolism; Pharmaceutical Preparations
First sentence: The kidneys can be exposed to high concentrations of drugs and toxicants present in the blood because they receive nearly 25% of the cardic output, have the ability to concentrate tubular fluids, and have several active transport systems that can cause the accumulation of organic acids, organic bases, and other chemicals into kidney cells.