Recombinant antibodies for immunotherapy
By: edited by Melvyn Little.
Contributors: Little, Melvyn, 1945-
Publisher: Cambridge University Press
Published: 2009
Place of publication: Cambridge; New York
Language: eng
ISBN-13: 9780521887328
Subjects: Monoclonal antibodies -- Therapeutic use; Immunotherapy -- methods; Antibodies, Monoclonal -- therapeutic use; Recombinant Proteins -- therapeutic use
Notes: Includes bibliographical references and index.
Table of contents: title: Humanization of recombinant antibodies / José W. Saldanha; title: Immunogenicity assessment of antibody therapeutics / Philippe Stas ... [et al.]; title: In vitro screening for antibody immunogenicity / Frank J. Carr and Matthew B. Baker; title: Antibody libraries from naïve V gene sources / Gerald Beste and David Lowe; title: Antibodies from IgM libraries / Vera Molkenthin and Stefan Knackmuss; title: The generation and screening of synthetic antibody libraries / Inge Klagge; title: Therapeutic antibodies from xenomouse transgenic mice / Aya Jakobovits; title: Transgenic chimeric antibodies / Andrew Murphy; title: Mechanisms of tumour cell killing by therapeutic antibodies / Ross Stewart and Carl Webster; title: Optimization of Fc domains to enhance antibody therapeutics / Greg A. Lazar and Aaron K. Chamberlain; title: Glycoengineered therapeutic antibodies / Peter Brünker, Peter Sondermann, and Pablo Umana; title: Monoclonal antibodies for the delivery of cytotoxic drugs / David J. King; title: Immunotherapy with radioimmune conjugates / Christina A. Kousparou and Agamemnon A. Epenetos; title: Immunotherapeutic antibody fusion proteins / Nigel S. Courtenay-Luck and David Jones; title: Alternative antibody formats / Fabrice Le Gall and Melvyn Little; title: Single domain antibodies / Serge Muyldermans; title: Engineering of non-CDR loops in immunoglobulin domains / Florian Rüker and Gordana Wozniak-Knopp; title: Alternative scaffolds : expanding the options of antibodies / Andreas Plueckthun; title: Polymer fusions to increase antibody half-lives : PEGylation and other modifications / Sam P. Heywood and David P. Humphreys; title: Extending antibody half-lives with albumin / Jan Terje Andersen and Inger Sandlie; title: A stem cell-based platform for the discovery and development of anti-tumor therapeutic antibodies to novel targets / Jennie P. Mather ... [et al.]; title: Antibody directed enzyme prodrug therapy (ADEPT) / Helen L. Lowe ... [et al.]; title: Immune privilege and tolerance - therapeutic antibody approaches / Daron Forman ... [et al.]; title: Antibody therapeutics : business achievements and business outlook / Christophe Bourrilly.