Handbook of Clinical Drug Data
Publisher: McGraw-Hill Medical
Published: September 11, 2001
Language: eng
Number of pages: 1104
ISBN-13: 9780071363624
First sentence: Dihydroergotamine (DHE) is a semisynthetic ergot alkaloid that is hypothesized to exert its antimigraine effect via its agonist activity at the serotonin 5-HT receptor, resulting in vasoconstriction of intracranial blood vessels and inhibition of inflammatory neuropeptide release.