The role of intramolecular interactions in HHR23A function in ubiquitin-mediated protein degradation
By: a thesis presented by Amanda Magdalene Chan
Published: 2005
Language: eng
Number of pages: 249
Subjects: Ubiquitin; Proteins; Metabolism; Protease inhibitors; DNA repair
Notes: Thesis (Ph. D., Division of Medical Sciences (Virology))--Harvard University, 2005.

Includes bibliographical references (leaves 200-215).
Table of contents: title: Includes four offprints :; title: DNA-repair protein hHR23a alters its protein structure upon binding proteasomal subunit S5a -- (Proceedings of the National Academy of Sciences, v. 100:22, October 28, 2003, pp. 12694-12699); title: Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a -- (Biochemistry, v. 41, 2002, pp. 1767-1777); title: Ubiquitin recognition by the DNA repair protein hHR23a -- (Biochemistry, v. 42, 2003, pp. 13529-13535); title: Ubiquitin family proteins and their relationship to the proteasome : a structural perspective-- (Biochemica et biophysica acta, no. 1695, 2004, pp. 73-87)