Alternatives to animal testing
By: editors, R.E. Hester and R.M. Harrison
Contributors: Royal Society of Chemistry (Great Britain)
Series: Issues in environmental science and technology -- 23
Publisher: Royal Society of Chemistry
Published: 2006
Place of publication: Cambridge
Language: eng
Format: [electronic resource] /
ISBN-13: 9781847552457
Subjects: Alternative toxicity testing; Animal experimentation
Other titles: RSC ebook collection.
Notes: Includes bibliographical references and index.
Table of contents: title: GENERAL OVERVIEW OF THE SAFETY EVALUATION OF CHEMICALS / Paul Illing; title: Introduction; title: Legislation and regulatory requirements; title: The regulatory paradigm; title: The interface between toxicology and risk assessment; title: Interpreting toxicology; title: Conclusions; title: References; title: INTERNATIONAL VALIDATION AND BARRIERS TO THE VALIDATION OF ALTERNATIVE TESTS / Michael Balls; title: Introduction; title: Background to the validation process; title: The validation process; title: Problems being encountered in implementing the validation process; title: The need for an invalidation process; title: Concluding remarks; title: References; title: IN VITRO TESTING FOR ENDOCRINE DISRUPTORS / Robert D. Combes; title: Introduction; title: In silico approaches; title: In vitro tests for EDs; title: Discussion; title: Conclusions; title: Acknowledgment; title: References; title: iNTELLIGENT APPROACHES TO SAFETY EVALUATION / Derek J. Knight; title: Introduction; title: Hazardous properties assessment; title: Risk assessment; title: Existing studies and literature data; title: Surrogate data: calculation, read across and SAR/QSAR; title: Alternatives to animal toxicology studies; title: Data waivers; title: Expert reports and weight of evidence; title: Preliminary risk assessments; title: EU Registration, Evaluation and Registration Scheme (REACH); title: Data for REACH; title: Regulatory planning & liaison with the regulators; title: Common themes; title: Acknowledgments; title: References; title: ALTERNATIVE TESTS AND THE 7TH AMENDMENT TO THE COSMETICS DIRECTIVE / Carl Westmoreland; title: Introduction; title: Overview of current approaches to risk assessment for cosmetics; title: 7th Amendment to the EU Cosmetics Directive (76/768/EEC); title: Status of alternative tests; title: Endpoints where risk assessment for cosmetics can be achieved without using animal data; title: Endpoints where risk assessment for cosmetics cannot currently be achieved without using animal data; title: New approaches to risk assessment without animals; title: Acknowledgments; title: Abbreviations; title: References.