The Genetics of Autoimmunity (Novartis Foundation Symposia)
Publisher: Wiley
Published: June 17, 2005
Language: eng
Format: Hardcover
Number of pages: 260
ISBN-13: 9780470021378
Subjects: Immunology; Medical / Immunology; Medical; Medical / Nursing; Autoimmunity; Congresses; Genetic aspects
First sentence: Here I will give an overview of the current research status of variable drug-response studies and some suggestions as to where they are likely to lead us in the coming years.
Description: Immunological diseases result from the combined effects of environmental triggers and inherited susceptibility genes. Studies of human autoimmune diseases show that patients with organ-specific autoimmunity have activated, autoreactive T cells specific for the target tissue. However, conventional immunological studies have not identified the next level of pathogenesis of spontaneous autoimmune diseases. There has consequently been great interest in identifying genes conferring susceptibility to autoimmune diseases. This book focuses on genes that may be associated with autoimmunity, how they can be identified, and how the functions of the gene products can be elucidated.