Antimicrobial drug discovery
Subtitle: emerging strategies
By: editors, George Tegos and Eleftherios Mylonakis
Series: Advances in molecular and cellular microbiology -- 22; Advances in molecular and cellular microbiology -- 22.
Publisher: CABI
Published: 2012
Place of publication: Wallingford, Oxfordshire
Language: eng
Number of pages: 357
ISBN-13: 9781845939434
Subjects: Animal Disease Models; Methods; Pharmacology; High-Throughput Screening Assays; Anti-Infective Agents; Photosensitizing Agents; Drug Design
Notes: Includes bibliographical references and index.
Table of contents: title: Emerging discovery strategies : an evolving necessity / Anthony R. Ball and George P. Tegos; title: The antibiotic crisis / Arnold L. Demain and Jaroslav Spizek; title: Structure, genetic regulation, physiology and function of the AcrAB-TolC efflux pump of escerichia coli and salmonella / Leonard Amaral ... [et al.]; title: Small molecule efflux pump inhibitors from natural products as a potential source of antimicrobial agents / Sanjay M. Jachak ... [et al.]; title: Fungal efflux-mediated resistance : from targets to inhibitors /  Brian C. Monk ... [et al.]; title: Vacuolar ATPase (V-ATPase) : a model proton pump for antifungal drug discovery; title: Karlett J Parra; title: Drug tolerance, persister cells and drug discovery / Kim Lewis; title: Inhibition of quorum sensing as a novel antimicrobial strategy; title: Gilles Brackman, Hans J. Nelis and Tom Coenye; title: Filamentous temperature-sensitive mutant Z (FtsZ) protein as an antibacterial target / Jaroslaw M. Boberek ... [et al.]; title: Lysostaphin : a silver bullet for staph / John F. Kokai-Kun; title: Strategies to identify modified ribosomally synthesized antimicrobials; title: Alan J. Marsh ... [et al.]; title: QSAR based discovery of antimicrobial peptides active against multidrug resistant bacteria / Christopher D. Fjell ... [et al.]; title: Acetyl-CoA carboxylase as a target for antibacterial development / Grover L. Waldrop; title: Underexploited targets in LPS biogenenesis for the design of antibacterials / Laura Cipolla ... [et al.]; title: Predicting and dissecting biomolecular interactions by information-driven docking / Panagiotis Kastritsis & Alexandre M.J.J Bonvin; title: Anti-fungals and anti-fungal drug discovery / Richard Calderone ... [et al.]; title: Pathosystematic studies and the rational design of antifungal interventions / Elaine M Bignell and Darius Armstrong-James; title: In vivo high-throughput antimicrobial discovery screens utilizing caenorhabditis elegans as an alternative host / Jeffrey J. Coleman and Eleftherios Mylonakis; title: Drosophila melanogaster as a versatile model for discovery of drugs effective against human microbe-induced infection and pathology / Yiorgos Apidianakis and Dimitrios P. Kontoyiannis; title: Antimicrobial photosensitizers - harnessing the power of light to treat infections / Sulbha K Sharma, Tianhong Dai and Michael R Hamblin; title: Nanoparticle platforms for antimicrobial therapy / David Trofa, Joshua D. Nosanchuk; title: Antimicrobial activity of carbon nanotubes / Shaobin Liu, Yuan Chen.