Biotransformation and metabolite elucidation of xenobiotics
By: edited by Ala F. Nassar
Publisher: John Wiley & Sons; Wiley
Published: 2011
Place of publication: Hoboken, N.J
Language: eng
Number of pages: 344
ISBN-13: 9780470504789
Notes: Includes bibliographical references and index.
Table of contents: title: Human biotransformation / Andrew Parkinson; title: Analytical tools and approaches for metabolite identification in drug metabolism / Yongmei Li; title: Tools of choice for accelerating metabolite identification : mass spec technology drives metabolite identification studies forward / Ala Nassar; title: Improving drug design : considerations for the structural modification process / Ala Nassar; title: Case study : the unanticipated loss of N2 from novel dna alkylating agent laromustine by collision-induced dissociation : novel rearrangements / Ala Nassar, Tukiet T. Lam; title: Case study : identification of in vitro metabolite/decomposition products of the novel DNA alkylating agent laromustine / Ala Nassar, TuKiet T. Lam; title: Strategies for the detection of reactive intermediates in drug discovery and development / Mark P. Grillo; title: Safety testing of drug metabolites : MIST guidance impact on the practice of industrial drug metabolism / J. Greg Slatter.