2-butenal
By: first draft prepared by J. Kielborn and I. Mangelsdorf ; and K. Ziegler-Skylakakis
Contributors: Mangelsdorf, I.; Ziegler-Skylakakis, K.; World Health Organization; United Nations Environment Programme; International Labour Organisation; International Program on Chemical Safety; Inter-Organization Programme for the Sound Management of Chemicals
Series: Concise international chemical assessment document -- 74; Concise international chemical assessment document -- 74.
Publisher: World Health Organization
Published: 2008
Place of publication: Geneva
Language: eng
Number of pages: 47
ISBN-13: 9789241530743
Subjects: Aldehydes; Risk Assessment; Environmental aspects; Crotonaldehyde; Physiological effect; Toxicology; Adverse effects; Pharmacokinetics; Toxicity; Environmental Exposure
Other titles: Two-butenal
Description: 2-Butenal (also known as crotonaldehyde) is an ab-unsaturated aldehyde and consequently a very reactive compound. It is a chemical intermediate used chiefly in the manufacture of sorbates, solvents, and, to a lesser extent, pharmaceutical products and aroma chemicals.  This publication studies the pharmacokinetics, environmental exposure, chemical toxicology and carcinogenicity of 2-butenal.  However, to enable an understanding and evaluation of this aldehyde in the context of environmental health, other aldehydes, such as formaldehyde, acetaldehyde, and acrolein, are mentioned for comparison.--Publisher's description.
Notes: "IPCS, International Programme on Chemical Safety"--Cover.

"Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organization, and the World Health Organization, and produced within the framework of the Inter-Organization Programme for the Sound Management of Chemicals."

Includes bibliographical references (p. 32-38).

Also freely available online.

Summaries in French and Spanish.
Table of contents: title: Identity and physical/chemical properties; title: Analytical methods; title: Sources of human and environmental exposure; title: Environmental transport, distribution, transformation and accumulation; title: Environmental levels and human exposure; title: Comparative kinetics and metabolism in laboratory animals and humans; title: Effects on laboratory mammals and in vitro test systems; title: Effects on humans; title: Effects on other organisms in the laboratory and field; title: Effects evaluation; title: Previous evaluations by IOMC bodies.