Chemokines, Volume 287 (Methods in Enzymology)
Contributors: John N. Abelson (Editor); Melvin I. Simon (Editor); Richard Horuk (Editor)
Publisher: Academic Press
Published: September 26, 1997
Language: eng
Number of pages: 421
ISBN-13: 9780121821883
First sentence: The expression plasmid pMG34 was designed for the secretion of mature MGSA into the E. coli periplasmic space (Fig. 1).
Description: Chemokines are major mediators of immune cells and are involved in a wide range of proinflammatory human diseases, including rheumatoid arthritis, multiple sclerosis, and organ transplant rejection. It has recently been discovered that their receptors are involved in HIV infection. The characterization of these molecules and their receptors is thus of primary importance in understanding a number of human diseases and infections. This volume and its companion Volume 288 on Chemokine Receptors provide comprehensive experimental protocols used in this field of research. Key Features * C-X-C Chemokines * C-C and C Chemokines * Other Methods.