Innovative drug development for headache disorders
By: [edited by] Jes Olesen, Nabih Ramadan.
Contributors: Olesen, Jes.; Ramadan, Nabih.
Series: Frontiers in headache research series -- v. 16.; Frontiers in headache research -- v. 16
Publisher: Oxford University Press
Published: 2008
Place of publication: Oxford; New York
Language: eng
ISBN-13: 9780199552764
Subjects: Headache -- Chemotherapy; Analgesics; Drug development; Headache Disorders -- drug therapy; Headache Disorders -- prevention & control
Notes: Includes bibliographical references and index.
Table of contents: title: The human GABA transporter GAT-2 : from cloning to high throughput screening / Bolette Christiansen ... [et al.]; title: Low throughput preclinical models for headache / Peter J. Goadsby; title: Human models : screening models / Messoud Ashina; title: Stricter success criteria, qualitative and quantitative end-points : acute versus prevention trials / Peer Tfelt-Hansen; title: Health-related quality of life and similar end-points / Carl G.H. Dahlöf; title: Clinically relevant designs and outcome measures for acute migraine trials / Michel D. Ferrari and Hille Koppen; title: Effectiveness of different steroid dosage in Tolosa/Hunt syndrome with different phenotypes : some critical points about the new International Headache Society classification / E. Marchioni ... [et al.]; title: Discussion summary : trial methodology / Jes Olesen; title: Inducible nitric oxide synthase and development of new migraine treatments / Boris A. Chizh; title: Mechanisms of cortical spreading depression as targets for migraine therapy / Kevin C. Brennan and Andrew C. Charles; title: Tonabersat / Peter R. Blower and Paul C. Sharpe; title: Discussion summary : nitric oxide and spreading depression modulators / Nabih Ramadan; title: Calcitonin gene-related peptide : relevance for migraine / Jes Olesen and Inger Jansen-Olesen; title: New 5-hydroxytryptamine-related drug targets / Pramod R. Saxena; title: Effect of two novel calcitonin gene-related peptide-binding compounds in a closed cranial window rat model / Louise Juhl ... [et al.]; title: Vasoactive intestinal polypeptide is unlikely to be a target for headache and migraine treatment / Jacob Müller Hansen; title: Discussion summary : calcitonin gene-related peptide and 5-hydroxytryptamine modulators / Rigmor Jensen; title: Migraine : from genes to pathophysiology, transgenic mouse models of migraine / Arn M.J.M. van den Maagdenberg; title: KATP channels and migraine / Inger Jansen-Olesen and Kenneth Beri Ploug; title: Antiepileptic drugs and migraine / Michael A. Rogawski; title: Discussion summary : ion channel modulators and antiepileptics / Pramod R. Saxena; title: Innovative drug development for headache disorders : glutamate / Kirk W. Johnson ... [et al.]; title: The modulation of TRPV1 channels by cannabinoid 1 receptors / Beatriz Fioravanti and Todd W. Vanderah; title: Future targets for headache therapy : prostanoids / Christian Waeber; title: Role of anandamide in the modulation of nitroglycerin-induced hyperalgesia : a study in the rat / Cristina Tassorelli ... [et al.].