Immunotherapy of cancer
Subtitle: methods and protocols
By: edited by Patricia Yotnda
Series: Springer protocols; Methods in molecular biology -- 651; Springer protocols; Methods in molecular biology (Clifton, N.J.) -- v. 651.
Publisher: Humana Press
Published: 2010
Place of publication: New York
Language: eng
Number of pages: 356
ISBN-13: 9781607617853; 9781607617860
Subjects: Immunotheraphy; Methods; Cancer; Neoplasms; Immunotherapy; Therapy; Immunology; Laboratory Manuals
Description: A continuously evolving technique, immunotherapy for the treatment of cancers now incorporates the use of immune cells infused during bone marrow transplants as well as approaches like cell and gene therapy, while stem cell-based therapies, tissue engineering, and targeting have also contributed to the latest successes in pre-clinical immunotherapy studies. In Immunotherapy of Cancer: Methods and Protocols, expert researchers in the field describe detailed procedures for trainees and experts in the area of basic, clinical science who wish to undertake their own cutting-edge immunotherapy studies. In addition to the protocols, the volume also contains two general overviews providing useful updates in each area as well as summaries of recent pre-clinical and clinical trials. Written in the highly successful Methods in Molecular Biology"!series format, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Immunotherapy of Cancer: Methods and Protocols seeks to guide scientists along the path to a further developed system of immunotherapeutic treatments in order to reduce and hopefully eradicate this terrible disease
Notes: Includes bibliographical references and index.

Also available online.
Table of contents: title: Hypoxic tumors and their effect on immune cells and cancer therapy / Patricia Yotnda, Danli Wu, and Anna May Swanson; title: Characterization of regulatory T cells in tumor suppressive microenvironments / Guangyong Peng; title: Generation of cytotoxic T lymphocytes for immunotherapy of EBV-associated malignancies / Corey Smith and Rajiv Khanna; title: Acquisition, preparation, and functional assessment of human NK cells for adoptive immunotherapy / Dean A. Lee, Michael R. Verneris, and Dario Campana; title: Enhanced migration of human dendritic cells expressing inducible CD40 / Natalia Lapteva; title: Differentiation of human embryonic stem cells into hematopoietic cells in vitro / Eun-Mi Kim and Nicholas Zavazava; title: Gene therapy to improve migration of T cells to the tumor site / Antonio Di Stasi, Biagio De Angelis, and Barbara Savoldo; title: Gene therapy to improve function of T cells for adoptive immunotherapy / Concetta Quintarelli, Barbara Savoldo, and Gianpietro Dotti; title: Cytokine-FC fusion genes as molecular adjuvants for DNA vaccines / Daniel Hirschhorn-Cymerman and Miguel-Angel Perales; title: Pharmacology of anti-CD3 diphtheria immunotoxin in CD3 positive T-cell lymphoma trials / Jung Hee Woo ... [et al.]; title: Construction of human antibody gene libraries and selection of antibodies by phage display / Thomas Schirrmann and Michael Hust; title: Identification of immunogenic peptides of the self-tumor antigen : our experience with telomerase reverse transcriptase / Xochitl Cortez-Gonzalez and Maurizio Zanetti; title: Rescue, amplification, purification, and PEGylation of replication defective first-generation adenoviral vectors / Michael A. Barry, Eric A. Weaver, and Sean E. Hofherr; title: Adenovirus-mediated interleukin (IL)-24 immunotherapy for cancer / Rajagopal Ramesh ... [et al.]; title: Liposomes for gene transfer in cancer therapy / Nancy Smyth Templeton; title: Oncolytic HSV as a vector in cancer immunotherapy / Hongtao Li and Xiaoliu Zhang; title: Generation of chimeric T-cell receptor transgenes and their efficient transfer in primary mouse T lymphocytes / Linda J. Howland, Nicole M. Haynes, and Phillip K. Darcy; title: Multi-walled carbon nanotube (MWCNT) synthesis, preparation, labeling, and functionalization / Babak Kateb ... [et al.]; title: Cellular immunotherapy of cancer / Fatma V. Okur and Malcolm K. Brenner.