Renin angiotensin system and the heart
By: edited by Walmor C. De Mello.
Contributors: De Mello, Walmor C.
Publisher: John Wiley & Sons
Published: 2004
Place of publication: Hoboken, NJ
Language: eng
Number of pages: 244
Subjects: Renin-angiotensin system; Heart -- Physiology; Heart -- Pathophysiology
Description: Recent studies have shown that the heart possesses an intrinsic renin angiotensin system that is controlled by tissue-specific parameters that are activated by biomechanical stress. This book reviews the latest information on the way in which both the plasma and cardiac renin angiotensin systems affect heart function. It covers the cell and molecular biology of these systems, with contributions on renin synthesis, uptake and the intracellular signalling pathways. Particular insight comes from transgenic mouse models in which either mouse or human genes for various components of the renin angiotensin system are expressed. Other topics covered are wound healing as well as the trophic effects of aldosterone.
Notes: Includes bibliographical references and index.
Table of contents: title: Intracellular signaling and the cardiac renin angiotensin system / George W. Booz and Kenneth M. Baker; title: Cardiac physiology and the renin-angiotensin system: lessons from transgenic animal models / Alisdair Ryding and John J. Mullins; title: Prorenin uptake in the heart / A.H. Jan Danser; title: Role of local renin-angiotensin systems in cardiac damage / Michael Bader; title: Cardiac renin: de novo synthesis and uptake / J"rg Peters; title: The cardiac renin receptors / Geneviève Nguyen, Céline Burckle, and Benjamin Tremey; title: Angiotensin II AT2 receptors and cardiac function / Jun suzuki ... [et al.]; title: The heart, a target for the renin angiotension system: evidence of an intracrine system / Walmor C. De Mello; title: ACE2: its role in the counter-regulatory response to heart failure / Lawrence S. Zisman; title: Wound healing and the tissue renin-angiotensin-aldosterone system / Yao Sun, and Karl T. Weber; title: Trophic effects of aldosterone / Claude Delcayre ... [el al.]; title: Intracellular angiotensin and the actions of intracrine hormones / Richard N. Re; title: Angiotensin ii and myocardial fibrosis, clinical implications / Begoña López, Arantxa Gonzalez and Javier Díez; title: Hypertensive heart disease: significance of renin angiotensin system / Jasmina Varagic and Edward D Frohlich.