Histone deacetylases
Subtitle: transcriptional regulation and other cellular functions
By: edited by Eric Verdin.
Contributors: Verdin, Eric.
Series: Cancer drug discovery and development
Publisher: Humana Press; Humana
Published: 2006
Place of publication: Totowa, N.J
Language: eng
Number of pages: 352
Subjects: Histone deacetylase; Cell cycle; Enzymes; Cancer -- Chemotherapy; Histone Deacetylases -- physiology; Cell Cycle -- drug effects; Enzyme Repression -- physiology; Histone Deacetylases -- antagonists & inhibitors; Neoplasms -- drug therapy; Sirtuins -- physiology
Notes: Includes bibliographical references and index.
Table of contents: title: Histone deacetylase / Dominique Meunier and Christian Seiser; title: Biochemistry of multiprotein HDAC complexes / Alejandro Vaquero, Michael Scher, and Danny Reinberg; title: The biology of HDAC3 / Edward Seto; title: The biology of HDAC8, a unique class I histone deacetylase / David Waltregny and Vincent Castronovo; title: Regulation of muscle gene expression by histone deacetylases / Timothy A. McKinsey and Eric N. Olson; title: The class IIA histone deacetylases: functions and regulation / Herbert G. Kasler and Eric Verdin; title: Histone deacetylases in the response to misfolded proteins / J. Andrew McKee and Tso-Pang Yao; title: Comparison of sirtuin sequences between archaea and vertebrates / Roy A. Frye; title: Structure of the Sir2 family of NAD+-dependent histone/protein deacetylases / Kehao Zhao and Ronen Marmorstein; title: The enzymology of Sir2 proteins / Margie T. Borra and John M. Denu; title: The class III protein deacetylases: homologs of yeast Sir2P / Bjoern Schwer ... [et al.]; title: HDAC inhibitors: discovery, development, and clinical impacts / Akihiro Ito, Norikazu Nishino, and Mitsuaki Yoshida; title: Cell cycle targets of histone deacetylase inhibitors / Brian Gabrielli; title: HDAC inhibitors: an emerging anticancer therapeutic strategy / Paul Kwon, Meier Hsu, Dalia Cohen, and Peter Atadja.