The COST manual of laboratory animal care and use
Subtitle: refinement, reduction, and research
By: edited by Bryan Howard, Timo Nevalainen, Gemma Perretta
Contributors: European Cooperation in the Field of Scientific and Technical Research (Organization)
Publisher: CRC Press
Published: 2011
Place of publication: Boca Raton
Language: eng
ISBN-13: 9781439824924
Description: "Our intention is to offer a one-stop source of best practice, which will be of value to personnel responsible for the care and welfare of animals and scientists conducting activities related to the use of animals for scientific purposes. It is also addressed to those with management responsibilities including facility engineers, architects and lay persons involved with ethical review, and the interested general reader. The manual presents perceived best practices and, as far as possible, the contents are evidence based. In the many cases / Summary: where the evidence is poor, the authors have endeavoured to demonstrate the rationale underlying their contentions by including relevant references. The emphasis is not on describing current practices, but rather what is seen as good practice; moreover it is not our intention to tell the reader what to do, but rather to offer options and provide advice on what not to do."--
Notes: Includes bibliographical references and index.
Table of contents: title: (Publisher-supplied data) Introduction / Bryan Howard; title: Design and Oversight of Laboratory Animal Facilities / Dag Sørensen ... [et al.]; title: Housing and Care of Laboratory Animals / Hanna-Marja Voipio ... [et al.]; title: Animal Needs and Environmental Refinement / Vera Baumans, Hanna Augustsson, and Gemma Perretta; title: Ethical Evaluation of Scientific Procedures Recommendations for Ethics Committees / Rony Kalman ... [et al.]; title: Reduction by Careful Design and Statistical Analysis / Michael Festing; title: Animal Models  Selecting and Preparing Animals for a Study / Patrick Hardy and Sarah Wolfensohn; title: Creation of Genetically Modified Animals /  Belen Pintado and Marian van Roon; title: Management of Genetically Modified Rodents / Jan-Bas Prins; title: Impact of Handling, Radiotelemetry, and Food Restriction / Timo Nevalainen ... [et al.]; title: Basic Procedures: Dosing, Sampling and Immunisation / Ismene Dontas, Jann Hau, and Katerina Marinou; title: Imaging Techniques / Aurora Brønstad and Ismene Dontas; title: Anaesthesia and Analgesia / Patricia Hedenqvist, and Paul Flecknell; title: Use of Humane Endpoints to Minimise Suffering / Coenraad Hendriksen, David Morton, and Klaus Cussler; title: Euthanasia / Luis Antunes; title: Education, Training and Competence / Bryan Howard, Katey Howard,  and Peter Sandøe; title: Animal Experimentation and Open Communication / Ann-Christine Eklöf, Anne-Grethe Berg, and Jon Richmond.