Components and predictors of delay to the diagnosis of acute pediatric arterial ischemic stroke.
Published: 2006
Language: eng
Number of pages: 230
ISBN-13: 9780494161791
Description: Results. 209 children with AIS were studied. Median interval from symptom onset to AIS diagnosis was 22.7 hours, ED arrival was 1.7 hours, initial assessment was 16-minutes and initial neuroimaging was 8.8 hours. Initial neuroimaging diagnosed AIS in 47%. Parent's help seeking action, non-abrupt symptoms, altered consciousness, milder stroke, posterior infarction and lack of initial neuroimaging at a tertiary hospital were predictive of delayed diagnosis.Background. Prompt diagnosis of pediatric arterial ischemic stroke (AIS) within 6-hours enables stroke specific thrombolytic and neuroprotective strategies.Methods. Retrospective study of prospectively enrolled children with AIS, admitted to The Hospital for Sick Children, Toronto, from January 1992-December 2004. Data on clinical presentation, symptom onset, emergency department (ED) arrival, neuroimaging and stroke diagnosis were recorded. Putative predictors of delayed diagnosis were selected a priori for univariate and multivariate analysis.Conclusion. In children with AIS, significant diagnostic delays exist. Efforts to reduce these delays can accelerate and optimize the management of AIS in children.
Notes: Source: Masters Abstracts International, Volume: 44-06, page: 2758.

Thesis (M.Sc.)--University of Toronto, 2006.

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