Flow cytometry in evaluation of hematopoietic neoplasms
Subtitle: a case-based approach
By: Sindhu Cherian, Brent Wood
Contributors: Wood, Brent L.
Publisher: CAP Press
Published: 2012
Place of publication: Northfield, Ill
Language: eng
Number of pages: 165
ISBN-13: 9780983706823
Subjects: Flow cytometry; Cytometry; Hematologic Neoplasms; Case Reports; Diagnosis; Flow Cytometry; Methods
Description: This book is a practical, case-based guide to flow cytometric analysis in the workup of hematopoietic neoplasms presenting in the peripheral blood, marrow, lymphoid tissue, and extranodal sites. Using multi-color techniques pioneered by Brent Wood, the text demonstrates a unique approach to diagnosis of hematopoietic malignancies as well as identification of small abnormal populations in the posttherapy setting (minimal residual disease testing). The publication contains an introduction to immunophenotypic changes seen in normal hematopoiesis along with an overview of the evaluation of lymphomas, leukemias, and myeloid stem-cell neoplasms. These concepts are further illustrated by a series of 36 cases, each dedicated to a specific disease entity. Each case provides detailed, full-color images of flow cytometric dot plots that clearly outline the features of the disease, accompanied by a clinical history and thorough discussion, enabling readers to develop and work through a differential diagnosis and recognize potential diagnostic pitfalls. Take-home points for each case emphasize critical concepts in flow cytometric diagnosis.--
Notes: Includes bibliographical references and index.