Familial breast and ovarian cancer
Subtitle: genetics, screening, and management
By: edited by Patrick J. Morrison, Shirley V. Hodgson, and Neva E. Haites.
Contributors: Morrison, Patrick J. 1963-; Hodgson, S. V.; Haites, Neva E. 1947-
Publisher: Cambridge University Press
Published: 2002
Place of publication: Cambridge, UK; New York
Language: eng
Number of pages: 401
Subjects: Breast -- Cancer.; Breast -- Cancer -- Genetic aspects.; Ovaries -- Cancer.; Ovaries -- Cancer -- Genetic aspects.; Breast Neoplasms -- genetics.; Ovarian Neoplasms -- genetics.
Description: "This book surveys the ramifications that have arisen from the significant advances in our understanding of the genetic basis of familial breast and ovarian cancer. Written by international experts from Europe and North America, it provides the busy clinician with a contemporary and wide-ranging guide to the latest developments in the diagnosis, genetics, screening, prevention and management of familial breast cancer. In this rapidly advancing field, this book provides an unrivalled source of information, including sections on ethical and insurance issues and the different cultural aspects of breast cancer. The use of recently devised cancer genetics clinics and different referral criteria and patterns to these clinics are also detailed. This book will be of value to all clinical geneticists, oncologists and healthcare professionals involved in screening and counselling programmes."--BOOK JACKET.
Notes: Includes bibliographical references and index.
Table of contents: title: Ch. 1. Introduction; title: Ch. 2. Overview of the clinical genetics of breast cancer; title: Ch. 3. Cowden syndrome and related disorders; title: Ch. 4. Overview of the clinical genetics of ovarian cancer; title: Ch. 5. Ovarian and breast cancer as part of hereditary non-polyposis colorectal cancer (HNPCC) and other hereditary colorectal cancer syndromes; title: Ch. 6. The natural history of hereditary breast cancer; title: Ch. 7. Pathology of the breast and ovary in mutation carriers; title: Ch. 8. Risk estimation for familial breast and ovarian cancer; title: Ch. 9. Developing a cancer genetics service: a Welsh model; title: Ch. 10. Referral criteria for cancer genetics clinics; title: Ch. 11. Guidelines for the development of cancer genetics services; title: Ch. 12. Cultural and educational aspects influencing the development of cancer genetics services in different European countries; title: Ch. 13. Screening, detection and survival patterns of breast and other cancers in high-risk families; title: Ch. 14. Screening for familial ovarian cancer; title: Ch. 15. Management of BRCA1/2 mutation carriers; title: Ch. 16. Management of familial ovarian cancer; title: Ch. 17. Prophylactic mastectomy in mutation carriers; title: Ch. 18. Psychosocial aspects of genetic counselling for breast and ovarian cancer; title: Ch. 19. BRCA1/2 testing: uptake and its measurement; title: Ch. 20. Breast cancer genetics: ethical, social and insurance issues; title: Ch. 21. Gene therapy for breast and ovarian cancer; title: Ch. 22. Future directions.