Mechanisms of CD4⁺ T cell tolerance in mixed allogenic bone marrow chimeras prepared with CD40L blockade
By: a thesis presented by Josef Michael Kurtz
Published: 2002
Language: eng
Number of pages: 163
Subjects: Bone marrow; Transplantation; Immunological aspects; CD antigens; CD4-Positive T-Lymphocytes
Notes: Thesis (Ph. D., Division of Medical Sciences (Immunology))--Harvard University, 2002.

Includes bibliographical references (leaves 142-162).
Table of contents: title: Includes two offprints :; title: Mechanisms involved in the establishment of tolerance through costinulary blockade and BMT: lack of requirement for CD40L-mediated signaling for tolerance or deletion of donor-reactive CD4⁺ cells -- (American journal of transplantation, 2001:1, pp. 339-349); title: CD4 T cell-mediated alloresistance to fully MHC-mismatched allogenic bone marrow engraftment is dependent on CD40-CD40 ligand interactions, and lasting T cell tolerance is induced by bone marrow transplantation with initial blockade of this pathway-- (Journal of immunology, v.166, 2001, pp. 2970-2981)