Design of human nutrigenomics studies
By: edited by S. Astley and L. Penn
Publisher: Wageningen Academic Publishers
Published: 2009
Place of publication: Wageningen, the Netherlands
Language: eng
Number of pages: 100
ISBN-13: 9789086866724; 9789086860944
Subjects: Nutrition; Nutrigenomics; Genetics; Genetic aspects; Metabolomics; Proteomics; Nutritional Physiological Phenomena
Description: The key to exploiting links between diet and health is to have a better understanding of how our bodies respond to what we eat. In the past, many food constituents were regarded as unimportant because they lacked a specific nutritional role. More recently nutritional research has been limited to a few dietary compounds, a handful of relevant biochemical pathways and a small number of genes pertinent to specific diseases. These studies have given rise to specific examples of benefits provided by individual/ groups of food compounds including non-nutrients, and demonstrated that whilst poor diet can accelerate age-related degeneration, a diet rich in fruits and vegetables, cereals and plant oils significantly reduces our risk of chronic disease. However, the benefits of dietary and lifestyle choices are not the same for everyone. Nutrigenomics offers a more holistic approach to nutritional research. It considers not only our genes and the effect they.
Notes: Includes bibliographical references.
Table of contents: title: ""1. Introduction""; ""G. A?nning1, M.M. Bergmann2 and J.C. Mathers3""; ""2. Transcriptomics applications in human nutrigenomics studies""; ""L. Afman and M. MA?ller""; ""3. A metabolomics study on human dietary intervention with apples""; ""L.O. Dragsted1, M. Kristensen2,3, G. Ravn-Haren1,3 and S. BA?gel1""; ""4. Metabolomics in human nutrition studies""; ""I. Bobeldijk-Pastorova1, S. Wopereis2, C. Rubingh1, F. van der Kloet2, H. Hendriks2, E. Verheij1 and B. van Ommen2""; ""5. Proteomics and the trouble with people""; ""A.C.J. Polley, I.T. Johnson and F. Mulholland""; title: ""6. Proteomic analysis of plasma, platelets and peripheral blood mononuclear cells in nutritional intervention studies""""B. de Roos""; ""7. Human nutrigenetic research: the strengths and limitations of various study designs""; ""A.M. Minihane""; ""8. Nutritional epigenomics in human studies""; ""J.C. Mathers""; ""9. References""