Triple Repeat Diseases of the Nervous Systems
By: edited by Lubov T. Timchenko
Series: Advances in Experimental Medicine and Biology, 0065-2598 -- 516; Advances in experimental medicine and biology -- 516.
Publisher: Springer US; Imprint: Springer
Published: 2002
Place of publication: Boston, MA
Language: eng
Format: [electronic resource] /
Number of pages: 126
ISBN-13: 9781461501176
Subjects: Medicine; Crystallography; Trees; Human genetics
Description: This book summarizes the current knowledge on the molecular bases for human inherited diseases associated with unstable mutations. Five chapters describe molecular mechanisms that destabilize normal regions of DNA and explain how repetitive elements cause such diseases. The book provides a balanced, objective account on all aspects and types of unstable mutations. The reader will find a solid background on how these mutations initiate unusual molecular pathways through DNA, RNA, and proteins. The book is designed to serve as a quick and comprehensive reference work for a broad audience including professors, researchers, students, and anyone with an interest in molecular medicine.