Development and validation of a paediatric comorbidity index using administrative data.
Published: 2004
Language: eng
Number of pages: 83
Description: Results. We identified 339,077 index discharges with 1988 deaths (i.e., 880 died &le;1 year). 1,294 distinct ICD-9-CM codes were recorded for all those that died. The top 200 were clustered into 127 diagnostic groups, which were further reduced to 37 with clinical appraisals and empirical modeling strategies. Stepwise logistic regression resulted in 27 predictor variables with a c-statistic of 0.825.Objective. To develop a risk index to predict death at 1-year post index discharge for paediatric patients between ages 1 and 14 years.Conclusion. The index demonstrated excellent discrimination with a high c-statistic.Methods. Retrospective study using administrative data obtained from CIHI Discharge Abstract Database and the Deaths File. From April 1 1991 through April 1 2002, index discharges for children between ages 1 and 14 years were compiled. Receiver Operating Characteristic curve was used to assess validity. Bootstrapping was used to determine the stability of parameter estimates.
Notes: Adviser:  Jim Wright.

Thesis (M.Sc.)--University of Toronto, 2004.

Electronic version licensed for access by U. of T. users.

Source: Masters Abstracts International, Volume: 43-03, page: 0838.

MICR copy on microfiche (1 microfiche).