Microarrays for an integrative genomics
By: Isaac S. Kohane, Alvin T. Kho, and Atul J. Butte.
Contributors: Kho, Alvin T.; Butte, Atul J.
Series: Computational molecular biology
Publisher: MIT Press
Published: 2003
Place of publication: Cambridge, Mass
Language: eng
Number of pages: 306
Subjects: DNA microarrays.; Genomics -- Automation.; Bioinformatics.
Description: Functional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level.This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics.
Notes: "A Bradford book."

Includes bibliographical references (p. [283]-295) and index.