An investigation of apolipoproteins, lipoproteins and the presenilin proteins in amyloid beta metabolism and Alzheimer's disease
By: a thesis presented by Philip Marcel Nadeau
Published: 2000
Language: eng
Number of pages: 186
Subjects: Apolipoproteins; Lipoproteins; Amyloid beta-protein
Notes: Thesis (Ph. D., Division of Medical Sciences (Neurobiology))--Harvard University, 2000.

Includes bibliographical references (leaves 164-184).
Table of contents: title: Includes two offprints :; title: Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations -- (Proceedings of the National Academy of Sciences, v. 96, June 1999, pp. 6959-6963); title: Presenilins are required for γ-secretase cleavage of β-APP and transmembrane cleavage of Notch-1-- (Nature cell biology, v. 2, July 2000, pp. 463-465); title: Includes copy of US patent :; title: Methods for decreasing beta amyloid protein -- Bruce A. Yankner, Philip Nadeau-- (patent number 6,080,778, June 27, 2000)