Quantitative drug design
Subtitle: a critical introduction
By: Yvonne Connolly Martin
Edition: 2nd ed.
Publisher: CRC Press/Taylor & Francis
Published: 2010
Place of publication: Boca Raton
Language: eng
Number of pages: 282
ISBN-13: 9781420070996
Notes: Includes bibliographical references and index.
Table of contents: title: Overview of quantitative drug design; title: Noncovalent interactions in biological systems; title: Preparation of 3D structures of molecules for 3D QSAR; title: Calculating physical properties of molecules; title: Biological data; title: Form of equations that relate potency and physical properties; title: Statistical basis of regression and partial least-squares analysis; title: Strategy for the statistical evaluation of a data set of related molecules; title: Detailed examples of QSAR calculations on erythromycin esters; title: Case studies; title: Methods to approach other structure-activity problems.