The challenges of systems biology
Subtitle: community efforts to harness biological complexity
By: edited by Gustavo Stolovitzky, Pascal Kahlem, and Andrea Califano.
Contributors: Stolovitzky, Gustavo.; Kahlem, Pascal.; Califano, Andrea.; DREAM2 Conference (2007 : New York, N.Y.); ENFIN-DREAM Conference (2008 : Madrid, Spain)
Series: Annals of the New York Academy of Sciences -- v. 1158; Annals of the New York Academy of Sciences -- v. 1158.
Publisher: Published by Blackwell Pub. on behalf of the New York Academy of Sciences
Published: 2009
Place of publication: Boston, Mass
Language: eng
Number of pages: 316
ISBN-13: 9781573317511
Subjects: Systems biology -- Congresses; Systems Biology -- Congresses; Gene Regulatory Networks -- Congresses
Genres: Congresses
Notes: "The volume is the result of the Second Dialogue on Reverse Engineering Assessment and Methods (DREAM2) Challenges, posed to the systems biology community between July and October, 2007; the DREAM2 Conference, held on December 3-4, 2007 at the New York Academy of Sciences in New York; and the ENFIN-DREAM Conference, Assessment of Computational Methods in Systems Biology, held on April 28-29, 2008 in Madrid, Spain"--P. v.

Includes bibliographical references and index.

Issued also online.
Table of contents: title: Ranking genes by their co-expression to subsets of pathway members / Priit Adler ... [et al.]; title: Creating reference datasets for systems biology applications using text mining / Martin Krallinger, Ana María Rojas, Alfonso Valencia; title: The condition-dependent transcriptional network in Escherichia coli / Karen Lemmens ... [et al.]; title: Reverse-engineering transcriptional modules from gene expression data / Tom Michoel ... [et al.]; title: Specification of spatial relationships in directed graphs of cell signaling networks / Azi Lipshtat, Susana R. Neves, Ravi Iyengar; title: Uncovering metabolic objectives pursued by changes of enzyme levels / Sabrina Hoffmann, Hermann-Georg Holzhütter; title: Modeling of gene regulatory network dynamics using threshold logic / Tejaswi Gowda, Sarma Vrudhula, Seungchan Kim; title: Global robustness and identifiability of random, scale-free, and small-world networks / Yunchen Gong, Zhaolei Zhang; title: The five-gene-network data analysis with local causal discovery algorithm using causal Bayesian networks / Changwon Yoo, Erik M. Brilz; title: Combining multiple results of a reverse-engineering algorithm: application to the DREAM five-gene network challenge / Daniel Marbach, Claudio Mattiussi, Dario Floreano; title: Network inference by combining biologically motivated regulatory constraints with penalized regression / Fabio Parisi, Heinz Koeppl, Felix Naef; title: A gene network simulator to assess reverse engineering algorithms / Barbara Di Camillo, Gianna Toffolo, Claudio Cobelli; title: A network inference workflow applied to virulence-related processes in Salmonella typhimurium / Ronald C. Taylor ... [et al.]; title: Lessons from the DREAM2 challenges : a community effort to assess biological network inference / Gustavo Stolovitzky, Robert J. Prill, Andrea Califano; title: DREAM2 challenge : integrated multi-array supervised learning algorithm for BCL6 transcriptional targets prediction / W.H. Lee ... [et al.]; title: A data integration framework for prediction of transcription factor targets : a BCL6 case study / Matti Nykter ... [et al.]; title: Inferring direct regulatory targets of a transcription factor in the DREAM2 challenge / Vinsensius B. Vega ... [et al.]; title: A probabilistic graph-theoretic approach to integrate multiple predictions for the protein-protein subnetwork prediction challenge / Hon Nian Chua ... [et al.]; title: Replaying the evolutionary tape : biomimetic reverse engineering of gene networks / Daniel Marbach, Claudio Mattiussi, Dario Floreano; title: Inferring gene networks : dream or nightmare? : part 1: challenges 1 and 3 / Angela Baralla, Wieslawa I. Mentzen, Alberto de la Fuente; title: NIRest : a tool for gene network and mode of action inference / Mario Lauria, Francesco Iorio, Diego di Bernardo; title: Reverse engineering of gene networks with LASSO and nonlinear basis functions / Mika Gustafsson ... [et al.]; title: Prediction of pairwise gene interaction using threshold logic / Tejaswi Gowda, Sarma Vrudhula, Seungchan Kim; title: Inferring gene networks : dream or nightmare? : part 2: challenges 4 and 5 / Alan Scheinine ... [et al.]; title: Inference of regulatory gene interactions from expression data using three-way mutual information / John Watkinson ... [et al.].