Molecular basis of drug design and resistance
By: edited by G.H. Coombs and S.L. Croft ; co-ordinating editor, L.H. Chappell.
Contributors: Chappell, Leslie H.; Coombs, Graham H., 1947-; Croft, S. L.; British Society for Parasitology.
Series: Symposia of the British Society for Parasitology -- volume 34.; Parasitology -- v. 114, supplement (1997); Symposia of the British Society for Parasitology -- v. 34.; Parasitology -- v. 114, suppl.
Publisher: Cambridge University Press
Published: 1997
Place of publication: Cambridge [England]; New York
Language: eng
Number of pages: 151
Subjects: Antiparasitic agents -- Congresses.; Parasitic diseases -- Chemotherapy -- Congresses.; Antiparasitic agents -- Design -- Congresses.; Drug resistance -- Congresses.
Notes: Includes bibliographical references and index.
Table of contents: title: Current status of antiparasite chemotherapy; title: Structure-based approach to drug discovery: crystallography and implications for the development of antiparasite drugs; title: Validating targets for antiparasite chemotherapy; title: Control of gene expression in viruses and protozoan parasites by antisense oligonucleotides; title: Parasite proteinases and amino acid metabolism: possibilities for chemotherapeutic exploitation; title: Mannitol cycle in Eimeria; title: Lipid biosynthesis pathways as chemotherapeutic targets in kinetoplastid parasites; title: New approaches to Leishmania chemotherapy: pteridine reductase 1 (PTR1) as a target and modulator of antifolate sensitivity; title: Target sites of anthelmintics; title: Quinoline resistance mechanisms in Plasmodium falciparum: the debate goes on; title: Role of drugs in the control of parasitic nematode infections: must we do without?; title: Designer drugs: pipe dreams or realities?