Homology folding of proteins
Subtitle: application to cytokine engineering
By: Subhashini Srinivasan.
Series: Biotechnology intelligence unit; Biotechnology intelligence unit (Unnumbered)
Publisher: Landes Bioscience; Springer-Verlag
Published: 1997
Place of publication: Austin, TX
Language: eng
Number of pages: 136
Subjects: Protein folding -- Computer simulation; Cytokines -- Structure -- Computer simulation
Description: The homology modeling method is an important tool in protein engineering and drug design when an experimental 3D structure is not available. Development of distance geometry-based homology modeling, offers a holistic approach to protein modeling thus expanding the scope of this method to protein threading and protein folding. This book is the first of its kind to give a complete account of the field, including structural principles and sequence-to-structural relationships in the PDB. This book is intended for use by biologists and modelers who are new to homology modeling methods, and serves as a good starting point for further research.
Notes: Includes bibliographical references and index.