New insights into BRCA1 function and its role in cancer development
Contributors: Livingston, David M.; Brugge, Joan; Dyson, Nick; Ganesan, Shridar; Haber, James
Published: 2014
Language: eng
Description: BRCA1 is a breast and ovarian tumor suppressor. The role of BRCA1 in the repair of double strand DNA breaks by homologous recombination [HR] is its best understood function and the function most often implicated in BRCA1 breast cancer suppression. However, BRCA1 has less well defined roles in multiple other molecular processes.
Notes: Thesis Ph.D. Harvard University 2014