Exploring the human plasma proteome
By: edited by Gilbert S. Omenn
Publisher: Wiley-VCH
Published: 2007
Place of publication: Weinheim
Language: eng
Format: [electronic resource] /
Number of pages: 372
ISBN-13: 9783527609420
Subjects: Biochemistry; Proteomics; Life Sciences; SCIENCE
Description: On the cutting edge of medical diagnostics, plasma proteomics promises to generate a new wave of technologies to help identify many different diseases and disease risks. Plasma and serum are the preferred non-invasive specimens to test normal individuals, at-risk groups, and patients for protein biomarkers discovered and validated to reflect physiological, pathological, and pharmacological phenotypes. These specimens present enormous challenges due to extreme complexity, huge dynamic range in protein concentrations, non-standardized methods of sample processing, and intra- and inter-individual.
Notes: Collection of articles published previously in the journal "Proteomics."

Includes bibliographical references and index.

Description based on print version record.
Table of contents: title: Exploring the Human Plasma Proteome; Table of Contents; Preface; List of Contributors; 1 Overview of the HUPO Plasma Proteome Project: Results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicl; 2 Data management and preliminary data analysis in the pilot phase of the HUPO Plasma Proteome Project; 3 HUPO Plasma Proteome Project specimen collection and handling: Towards the standardization of parameters for plasma proteome samples.