A study of coronary revascularization surgery in renal transplant candidates.
Published: 2004
Language: eng
Number of pages: 102
Description: In transplant candidates on dialysis, all-cause mortality post-ACB was 2.3%  in-hospital, 12% at 1-year and 30% at 5-years. A computer-assisted decision model simulated choice from a patient perspective. The strategy with highest quality-adjusted life gain was ACB and living-donor (LRD) transplantation. There was no difference between ACB and cadaver-donor (CD) transplantation versus life-long dialysis. Patient preference, age &lt;53-years, surgery risk &lt;6% and wait-time &lt;3.5 years favoured CD transplantation.ACB in transplant candidates can be viewed as safe and acceptable. The best management strategy would be ACB and LRD transplantation. Candidate and program variables that favour CD transplantation were identified.Appropriate management of renal transplant candidates with asymptomatic, surgically amenable, sub-critical (50--70%) coronary stenosis is a dilemma. To facilitate decision-making a cohort study evaluated the immediate risk and long-term outcome after revascularization surgery (ACB) in candidates prepared for transplantation. A decision analysis evaluated treatment strategies of ACB prior to transplantation versus life-long dialysis.
Notes: Adviser:  Alexander Logan.

Thesis (M.Sc.)--University of Toronto, 2004.

Electronic version licensed for access by U. of T. users.

Source: Masters Abstracts International, Volume: 42-06, page: 2157.

MICR copy on microfiche (2 microfiches).