Bone metastasis and molecular mechanisms
Subtitle: pathophysiology
By: edited by Gurmit Singh and William Orr.
Contributors: Singh, Gurmit.; Orr, F. William.
Series: Cancer metastasis-biology and treatment ;; v. 6; Cancer metastasis ;; v. 6
Publisher: Kluwer Academic
Published: 2004
Place of publication: Dordrecht; Boston
Language: eng
Number of pages: 308
Subjects: Bone metastasis; Cancer -- Pathophysiology; Cancer -- Molecular aspects
Description: Patients with advanced breast or prostate cancers usually develop bone metastases. The principal complications resulting from metastatic bone disease are pain, spinal cord compression, pathologic fractures and bone marrow suppression. Improving the management of bone metastases is crucial to quality of life for patients with breast and prostate cancer. Advances in understanding of the molecular mechanisms underlying the pathophysiology of bone metastasis are driving the development of new therapeutic strategies. The book provides an overview of molecular factors that offer targets and avenues for therapeutic strategies.
Notes: Includes bibliographical references and index.