Myasthenia gravis and related disorders
Subtitle: 12th international conference
By: issue editors, Gil I. Wolfe ... [et al.].
Contributors: Wolfe, Gil I.; New York Academy of Sciences
Series: Annals of the New York Academy of Sciences -- v. 1274-1275; Annals of the New York Academy of Sciences -- v. 1274.; Annals of the New York Academy of Sciences -- v. 1275.
Publisher: Published by Blackwell Pub. on behalf of the New York Academy of Sciences
Published: 2012
Place of publication: Boston, Mass
Language: eng
ISBN-13: 9781573318907; 9781573319119
Subjects: Myasthenia gravis; Congresses
Description: "Myasthenia gravis (MG), an acquired immune syndrome affecting proteins at the neuromuscular junction, causes significant muscular functional impairment and can compromise patients' quality of life, including fatigue, disability, and increased mortality rates. Continued efforts in the last decades have begun to produce significant progress in our understanding of this rare condition, yet considerable challenges remain for improving diagnosis and developing effective treatments for MG. The present volume comprises papers stemming from the '12th International Conference on Myasthenia Gravis and Related Disorders,' held May 21-23, 2012 at the New York Academy of Sciences in New York City. The papers collected in this second of two Annals volumes highlight some of the key developments in neuroscience and immunology in MG and related syndromes presented at the conference, including treatment update and what lies ahead, congenital myasthenic syndromes, Lambert-Eaton myasthenic syndrome, the thymus, thymectomy, and the myasthenia gravis thymectomy trial, and hot topics selected from submitted abstracts."--Publisher's description.
Notes: Includes bibliographical references.
Table of contents: title: v. 1. Introduction for Myasthenia gravis and related disorders / Gil I. Wolfe ... [et al.]; title: Biologics and other novel approaches as new therapeutic options in myasthenia gravis : a view to the future / Marinos C. Dalakas; title: Myasthenogenicity of the main immunogenic region / Jon Lindstrom and Jie Luo; title: Structure of the neuromuscular junction : function and cooperative mechanisms in the synapse / Masaharu Takamori; title: Active zones of mammalian neuromuscular junctions : formation, density, and aging / Hiroshi Nishimune; title: The etiology of autoimmune diseases : the case of myasthenia gravis / Jean-François Bach; title: Defects of immunoregulatory mechanisms in myasthenia gravis : role of IL-17 / Angeline Gradolatto ... [et al.]; title: Targeting plasma cells with proteasome inhibitors : possible roles in treating myasthenia gravis? / Alejandro M. Gomez ... [et al.]; title: The role of B cell-activating factor in autoimmune myasthenia gravis / Robert P. Lisak and Samia Ragheb; title: Functional defect in regulatory T cells in myasthenia gravis / Muthusamy Thiruppathi ... [et al.]; title: Jitter analysis with concentric needle electrodes / Erik Stålberg; title: Management challenges in muscle-specific tyrosine kinase myasthenia gravis / Amelia Evoli ... [et al.]; title: Antibodies identified by cell-based assays in myasthenia gravis and associated diseases / Angela Vincent ... [et al.]; title: The MG composite : an outcome measure for myasthenia gravis for use in clinical trials and everyday practice / Ted M. Burns; title: Patient registries : useful tools for clinical research in myasthenia gravis / Fulvio Baggi ... [et al.]; title: The Myasthenia Gravis-Specific Activities of Daily Living Profile / Srikanth Muppidi; title: Regulatory T cell-based immunotherapies in experimental autoimmune myasthenia gravis / Miriam C. Souroujon ... [et al.]; title: The role of complement in experimental autoimmune myasthenia gravis / Linda L. Kusner and Henry J. Kaminski; title: Novel animal models of acetylcholine receptor antibody-related myasthenia gravis / Erdem Tüzün ... [et al.]; title: Animal models of antimuscle-specific kinase myasthenia / David P. Richman ... [et al.].; title: v. 2. Introduction for Myasthenia gravis and related disorders / Gil I. Wolfe ... [et al.]; title: IVIG and PLEX in the treatment of myasthenia gravis / Vera Bril ... [et al.]; title: Antigen-specific apheresis of autoantibodies in myasthenia gravis / Konstantinos Lazaridis ... [et al.]; title: Further developments with antisense treatment for myasthenia gravis / Jon Sussman ... [et al.]; title: Design of the Efficacy of Prednisone in the Treatment of Ocular Myasthenia (EPITOME) trial / Michael Benatar ... [et al.]; title: Phase II trial of methotrexate in myasthenia gravis / Mamatha Pasnoor ... [et al.]; title: Identification of DPAGT1 as a new gene in which mutations cause a congenital myasthenic syndrome / Katsiaryna Belaya ... [et al.]; title: Synaptic basal lamina-associated congenital myasthenic syndromes / Ricardo A. Maselli ... [et al.]; title: DOK7 congenital myasthenic syndrome / Jacqueline Palace; title: New horizons for congenital myasthenic syndromes / Andrew G. Engel ... [et al.]; title: Synaptic dysfunction in congenital myasthenic syndromes / David Beeson; title: SOX1 antibodies in Lambert-Eaton myasthenic syndrome and screening for small cell lung carcinoma / Alexander F. Lipka, Jan J.G.M. Verschuuren, and Maarten J. Titulaer; title: Treatment in Lambert-Eaton myasthenic syndrome / Paul Maddison; title: New calcium channel agonists as potential therapeutics in Lambert-Eaton myasthenic syndrome and other neuromuscular diseases / Tyler B. Tarr ... [et al.]; title: Thymus pathology observed in the MGTX trial / Alexander Marx .... [et al.]; title: Biomarker development for myasthenia gravis / Henry J. Kaminski .... [et al.]; title: Experimental myasthenia gravis in Aire-deficient mice : a link between Aire and regulatory T cells / Revital Aricha ... [et al.]; title: Pathogenic IgG4 subclass autoantibodies in MuSK myasthenia gravis / Jaap J. Plomp ... [et al.]; title: The search for new antigenic targets in myasthenia gravis / Judith Cossins ... [et al.]; title: Neuromuscular transmission failure in myasthenia gravis : decrement of safety factor and susceptibility of extraocular muscles / Alessandro Serra, Robert L. Ruff, and Richard John Leigh.