Progress in medicinal chemistry
By: editors, F.D. King and A.W. Oxford
Edition: 1st ed.
Publisher: Elsevier Science
Published: 2001
Place of publication: Amsterdam; New York
Language: eng
Format: [electronic resource] /
Number of pages: 394
ISBN-13: 9780080862866
Subjects: Drug Guides; Nursing; Pharmacology; MEDICAL; Pharmacy; Trends; Medicine; Pharmaceutical chemistry; Pharmaceutical Chemistry
Description: Highlights of this volume include accounts of the biological rationale, design and clinical potential of drug molecules; summaries of structure-activity relationships in topical areas of medicinal chemistry; and evaluation of technologies in their application to drug action and design. The seven chapters describe advances in drug molecules and in the application of new technologies to drug discovery and development.
Notes: Includes bibliographical references and indexes.

Description based on print version record.
Table of contents: title: Front Cover; Progress in Medicinal Chemistry, Volume 38; Copyright Page; Preface; Contents; List of Contributors; Chapter 1.1 p38 MAP Kinase: Molecular Target for the Inhibition of Pro-inflammatory Cytokines; Chapter 2. The Adenosine A3 Receptor and its Ligands; Chapter 3. The Medicinal Chemistry of the P2 Receptor Family; Chapter 4. Radioligands for the Study of Brain 5-HT1A Receptors In Vivo; Chapter 5. Discovery of Montelukast: a Once-a-Day Oral Antagonist of Leukotriene D4 for the Treatment of Chronic Asthma; Chapter 6. The Histamine H3 Receptor and its Ligands