Textbook of bone metastases
By: editors, Claude Jasmin ... [et al.].
Contributors: Jasmin, Claude, 1938-
Publisher: J. Wiley & Sons
Published: 2005
Place of publication: Chichester; Hoboken, NJ
Language: eng
Number of pages: 568
Subjects: Bone metastasis; Bone Neoplasms -- secondary; Bone Neoplasms -- therapy
Description: The epidemiological and clinical importance of bone metastases has long been recognised. For example, the incidence of bone metastases in breast and prostate cancers is 70%, whereas it is only 30 to 40 0n metastatic lung cancer. In clinical terms, bone metastases have substantial negative effects on the patient's quality of life. This volume presents a broad approach to recent progress in all fields related to bone metastases, ranging from epidemiology to the physiopathology of bone metastases and therapeutics. It attempts to provide a better understanding of recent advances and, more importantly, should give clinicians all the information needed to help them in the clinical and therapeutic management of patients with bone metastases.
Notes: Includes bibliographical references and index.
Table of contents: title: General mechanisms of metastasis.; title: Parathyroid hormone-related protein and bone metastases.; title: Osteoblastic metastases.; title: The role of RANK, RANK ligand and osteoprotegerin in the lytic effects and growth of bone metastases.; title: Clinical features and prognosis of bone metastases.; title: Radioisotope and PET imaging of bone metastases.; title: Imaging of spinal bone metastases.; title: Monitoring response to treatment: the role of biochemical markers.; title: Surgical biopsy of bone metastases.; title: Indications for the surgical treatment of long bone metastases.; title: Prosthetic replacement in long bone metastases.; title: Osteosythesis for pathological fractures in long bones.; title: Surgical treatment of pelvic metastases.; title: Indications and strategy for the treatment of spinal metastases.; title: Surgical techniques for the treatment of bone metastases of the spine.; title: Total en bloc spondylectomy for spinal metastases.; title: External beam radiation therapy for the treatment of bone metastases.; title: Interventional radiology for bone metastases.; title: Percutaneous injection of ethanol.; title: Chemotherapy.; title: Endocrine treatment of bone metastases.; title: Overview of osteoclast inhibitors.; title: Radioisotopes and radioimmunoisotopes.; title: Immunotherapy.; title: Mechanisms of action of bisphosphonates.; title: Antitumour effects of bisphosphonates.; title: Management of hypercalcaemia.; title: Treatment of lytic bone metastases.; title: Use in multiple myeloma.; title: Use in prostate cancer.; title: Prevention of bone metastases.; title: Prevention of bone loss.; title: Cost implications of bisphosphonates.; title: Treatment of bone pain.; title: Specific approaches to cancer in the elderly.; title: Psychological and social aspects.; title: Metabolic bone diseases in childhood cancer.; title: Breast cancer.; title: Prostate cancer.; title: Multiple myeloma.; title: Malignant non-Hodgkin's lymphoma.; title: Lung cancer.; title: Kidney cancer.; title: Evaluation of the patient with bone metastases at presentation.