Wilms Tumor
Publisher: Codon Publications
Published: 2016 Mar
Place of publication: Brisbane, Australia
Language: eng
Format: Hardcover
Number of pages: 294
ISBN-13: 9780994438119
Other titles: Wilms' Tumour
Description: Wilms tumor is a rare kidney cancer that is usually diagnosed in children under the age of six. Wilms tumor is mostly the result of aberrations in WT1 gene, located on chromosome 11p13. In addition to being a risk factor for Wilms tumor, WT1 aberrations cause extra renal complications and other malignancies. This book brings together the basic and clinical aspects of Wilms tumor and WT1 research under three sections. Section I provides a comprehensive guide to the epidemiology, diagnostics, management, and treatment of Wilms tumor. Section II covers the biological aspects of Wilms tumor and WT1. Section III focuses on the role of WT1 in cardiac development, prostate cancer, glioblastoma and minimal residual disease.

Contributors: 64; Chapters: 16; Figures: 50; Tables: 20; Pages: 294
Notes: Copyright © 2016 Codon Publications.
Published under Creative Commons Attribution 4.0 International (CC BY 4.0). Users are allowed to share (copy and redistribute the material in any medium or format) and adapt (remix, transform, and build upon the material for any purpose, even commercially), as long as the authors and the publisher are explicitly identified and properly acknowledged as the original source.
Table of contents: title: Foreword; title: Preface; title: Contributors; title: Section I. Epidemiology, Diagnostics, and Treatment; title: 1. Wilms’ Tumour – Histology and Differential Diagnosis; title: 2. The Clinical Relevance of Age at Presentation in Nephroblastoma; title: 3. Histopathological and Molecular Characteristics of Wilms Tumor; title: 4. Wilms Tumor and Its Management in a Surgical Aspect; title: 5. Management of Bilateral Wilms Tumours; title: 6. Extrarenal Wilms’ Tumor: Challenges in Diagnosis, Embryology, Treatment and Prognosis; title: 7. Neoadjuvant Transcatheter Arterial Chemoembolization and Systemic Chemotherapy for the Treatment of Wilms Tumor; title: 8. Dendritic Cell-Based Cancer Immunotherapy Targeting Wilms’ Tumor 1 for Pediatric Cancer; title: 9. Chronic Kidney Disease in Wilms Tumour Survivors – What Do We Know Today?; title: Section II. Biology; title: 10. Gene Expression in Wilms Tumor: Disturbance of the Wnt Signaling Pathway and MicroRNA Biogenesis; title: 11. Transcriptional Regulation of the Human Thromboxane A2 Receptor Gene by Wilms’ Tumour (WT)1; title: 12. The Inflammatory Microenvironment in Wilms Tumors; title: Section III. WT1 Gene Aberrations in Other Malignancies; title: 13. WT1 in Cardiac Development and Disease; title: 15. Functional Roles of Wilms’ Tumor 1 (WT1) in Malignant Brain Tumors; title: 16. Wilms’ Tumor Gene (WT1) Expression and Minimal Residual Disease in Acute Myeloid Leukemia; title: Index