NMR primer
Subtitle: an HSQC-based approach with vector animations
By: Steven M. Pascal ; animations by Jennie M. McKelvie
Publisher: IM Publications
Published: 2008
Place of publication: Chichester
Language: eng
Number of pages: 129
ISBN-13: 9781901019087
Subjects: Magnetic resonance
Description: "This book has one aim: to explain the key two-dimensional protein NMR experiment, the 1H,15N-HSQC, along with variants and extensions, in a generally accessible manner. Vector diagrams of one-, two- and three-dimensional pulse sequences are provided, along with accompanying animated versions. The animations allow the evolution of net magnetisation during the course of the experiments to be visualised and directly compared with the corresponding spin operator terms. First, a brief introduction to spins, populations, the NMR experiment and relaxation is provided. Evolution due to J-coupling is next described and used to explain magnetisation transfer in the HSQC experiment and several variants. The extraction of structural, sequential and dynamic information is then illustrated via various extensions of the HSQC. Extensive footnotes and appendices introduce several more advanced concepts, such as sensitivity enhancement and the TROSY effect."--Publisher's description.
Notes: Includes bibliographical references and index.
Table of contents: title: The simplest one-dimensional NMR experiment; title: Two additional simple NMR experiments: measuring T1 and T2; title: J-coupling and the INEPT sequence element; title: The HSQC experiment (coupled, decoupled and gradient versions); title: 3D HSQC-based double resonance experiments; title: 3D HSQC-based triple resonance experiments; title: 2D HSQC-based 15N relaxation experiments.