Role of prostaglandins in neuroinflammatory and neurodegenerative diseases
Contributors: Oliveira, Antônio Carlos Pinheiro de Verfasser; Limborço-Filho, Marcelo Verfasser; Fiebich, Bernd L. Verfasser; Klinik für Psychiatrie und Psychotherapie; Albert-Ludwigs-Universität Freiburg Medizinische Fakultät; Albert-Ludwigs-Universität Freiburg
Publisher: Universität
Published: 2012
Place of publication: Freiburg
Language: eng
Subjects: Prostaglandine; Alzheimerkrankheit; Nervendegeneration; Hirnkrankheit; Neuropsychiatrie; Nervenkrankheit
Description: Abstract: Increasing data demonstrates that inflammation participates in the pathophysiology of neurodegenerative diseases. Among the different inflammatory mediators involved, prostaglandins play an important role. The effects induced by prostaglandins might be mediated by activation of their known receptors or by nonclassical mechanisms. In the present paper, we discuss the evidences that link prostaglandins, as well as the enzymes that produce them, to some neurological diseases
Notes: Mediators of Inflammation. 2012 (2012), Article ID 946813, 13 pages, DOI 10.1155/2012/946813, issn: 1466-1861

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