The mechanism of NAD-dependent deacetylation and its role in gene silencing in Saccharomyces cerevisiae
By: a thesis presented by Jason Chaim Tanny
Published: 2003
Language: eng
Number of pages: 165
Subjects: Saccharomyces cerevisiae; Genetics; Heterochromatin
Notes: Thesis (Ph. D., Division of Medical Sciences (Cell and Developmental Biology))--Harvard University, 2003.

Includes bibliographical references (leaves ).
Table of contents: title: Includes two offprints :; title: An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing -- (Cell, v. 99, December 23, 1999, pp. 735-745); title: Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2 : evidence for acetyl transfer from substrate to an NAD breakdown product -- Jason C. Tanny and Danesh Moazed-- (Proceedings of the National Academy of Sciences, v. 98:2, January 16, 2001, pp. 415-420)