Protein tyrosine kinases
Subtitle: from inhibitors to useful drugs
By: edited by Doriano Fabbro and Frank McCormick.
Contributors: Fabbro, D.; McCormick, Frank, 1950-
Series: Cancer drug discovery and development
Publisher: Humana Press
Published: 2006
Place of publication: Totowa, N.J
Language: eng
Number of pages: 290
Subjects: Protein-tyrosine kinase -- Inhibitors -- Therapeutic use.; Cancer -- Chemotherapy.
Notes: Includes bibliographical references and index.
Table of contents: title: Protein tyrosine kinases as targets for cancer and other indications / Mark Pearson, Carlos Garcia-Echeverria, Doriano Fabbro; title: Inhibitors of signaling interfaces: targeting Src homology 2 domains in drug discovery / Carlos Garcia-Echeverria; title: PI 3-kinase inhibition: a target for therapeutic intervention / Peter M. Finan, Stephen G. Ward; title: Src as a target for pharmaceutical intervention: potential and limitations / Mira Susa ... [et al.]; title: Activated FLT3 receptor tyrosine kinase as a therapeutic target in leukemia / Blanca Scheijen, James D. Griffin; title: JAK kinases in leukemias/lymphomas and multiple myeloma / Renate Burger, Martin Gramatzki; title: Glivec (Gleevec, Imatinib, STI571): a targeted therapy for CML / Elisabeth Buchdunger, Renaud Capedeville; title: Platelet-derived growth factor: normal function, role in disease, and applications of PDGF antagonists / Tobias Sjoblom ... [et al.]; title: Structural biology of protein tyrosine kinases / Sandra W. Cowan-Jacob ... [et al.]; title: Testing of signal transduction inhibitors in animal models of cancer / Terence O'Reilly, Robert Cozens; title: Phosphoproteomics in drug discovery and development / Michel F. Moran.