Contributions to Imputation Methods Based on Ranks and to Treatment Selection Methods in Personalized Medicine
Contributors: Betensky, Rebecca; Cai, Tianxi; Betensky, Rebecca; Cai, TIanxi; Finkesltein, Dianne
Published: 2012
Language: eng
Description: The chapters of this thesis focus two different issues that arise in clinical trials and propose novel methods to address them. The first issue arises in the analysis of data with non-ignorable missing observations. The second issue concerns the development of methods that provide physicians better tools to understand and treat diseases efficiently by using each patient's characteristics and personal biomedical profile.
Notes: Keywords: Composite outcome, Personalized medicine, power and sample size, Treatment selection, Wilcoxon test, Worst-rank scores.

Thesis Ph.D. Harvard University 2012