RNA Exosome
By: edited by Torben Heick Jensen
Contributors: SpringerLink (Online service)
Series: Advances in Experimental Medicine and Biology -- 702
Publisher: Landes Bioscience and Springer Science+Business Media, LLC
Published: 2010
Place of publication: New York, NY
Language: eng
Format: [electronic resource] /
Number of pages: 146
ISBN-13: 9781441978400; 9781441978417
Subjects: Medicine
Description: "The diversity of RNAs inside living cells is amazing. We have known of the more "classic" RNA species: mRNA, tRNA, rRNA, snRNA and snoRNA for some time now, but in a steady stream new types of molecules are being described as it is becoming clear that most of the genomic information of cells ends up in RNA. To deal with the enormous load of resulting RNA processing and degradation reactions, cells need adequate and efficient molecular machines. The RNA exosome is arising as a major facilitator to this effect. Structural and functional data gathered over the last decade have illustrated the biochemical importance of this multimeric complex and its many co-factors, revealing its enormous regulatory power. By gathering some of the most prominent researchers in the exosome field, it is the aim of the book to introduce this fascinating protein complex and to give a timely and rich account of its many functions"--Provided by publisher.