Transgenic mouse methods and protocols
By: edited by Marten H. Hofker, Jan M. van Deursen
Edition: 2nd ed.
Series: Springer protocols; Methods in molecular biology -- 693; Springer protocols; Methods in molecular biology (Clifton, N.J.) -- v. 693.
Publisher: Humana Press
Published: 2011
Place of publication: New York
Language: eng
Number of pages: 352
ISBN-13: 9781607619734; 9781607619741
Subjects: Transgenic mice; Laboratory manuals
Notes: Previous ed.: 2003.

Includes bibliographical references and index.
Table of contents: title: Introduction: strategies for developing genetically modified mice / Marten H. Hofker; title: Genetic modification of the mouse : general technology-pronuclear and blastocyst injection / Jan Willem Voncken; title: Generation of chimeras by aggregation of embryonic stem cells with diploid or tetraploid mouse embryos / Jérôme Artus and Anna-Katerina Hadjantonakis; title: Cryopreservation of mouse spermatozoa and in vitro fertilization / Naomi Nakagata; title: Autopsy and histological analysis of the transgenic mouse / Marion J.J. Gijbels and Menno P.J. de Winther; title: Transgene design / Bart van de Sluis and Jan Willem Voncken; title: Inducible transgenic mouse models / Thomas L. Saunders; title: Lentiviral transgenesis / Terunaga Nakagawa and Casper C. Hoogenraad; title: Transgenesis in mouse embryonic stem cells / Janine van Ree, Wei Zhou, Ming Li, and Jan M. van Deursen; title: Engineering BAC reporter gene constructs for mouse transgenesis / Yu Fu and Peter Maye; title: Targeting vector construction through recombineering / Liviu A. Malureanu; title: Generating conditional knockout mice / Roland H. Friedel, Wolfgang Wurst, Benedikt Wefers, and Ralf Kühm; title: Hypomorphic mice / Darren J. Baker; title: MICER targeting vectors for manipulating the mouse genome / Chunhong Liu, Paul F. Szurek, and Y. Eugene Yu; title: Knock-in approaches / Anton J.M. Roebroek, Philip L.S.M. Gordts, and Sara Reekmans; title: Generation of a series of knock-in alleles using RMCE in ES cells / Anton J.M. Roebroek, Philip L.S.M. Gordts, and Sara Reekmans; title: Selection of targeted mutants from a library of randomly mutagenized ES cells / Kyoji Horie, George Gaitanaris, and Alexander Gragerov; title: Generation of genetically modified rodents using random ENU mutagenesis / Ruben van Boxtel and Edwin Cuppen; title: Bone marrow transplantations to study gene function in hematopoietic cells / Menno P.J. de Winther and Peter Heeringa; title: Adenovirus-mediated gene transfer / Ko Willems van Dijk, Kyriakos E. Kypreos, Frits J. Fallaux, and Jurre Hageman.