Lamarck's signature
Subtitle: how retrogenes are changing Darwin's natural selection paradigm
By: Edward J. Steele, Robyn A. Lindley, Robert V. Blanden.
Contributors: Lindley, Robyn A.; Blanden, R. V.
Series: Frontiers of science; Helix books; Frontiers of science (Reading, Mass.)
Publisher: Perseus Books
Published: 1998
Place of publication: Reading, Mass
Language: eng
Number of pages: 286
Subjects: Lamarck, Jean Baptiste Pierre Antoine de Monet de, 1744-1829; Darwin, Charles, 1809-1882; Immunogenetics; Evolutionary genetics; Clonal selection theory; Antibody diversity; RNA; Evolutionary genetics; Natural selection; DNA
Description: This controversial book challenges the accepted theories on the genetic mechanism of evolution. The story these three biologists have to tell may very well upset the whole field of biology.

The traditional view of evolution - which grew out of the work of Gregor Mendel and Charles Darwin and is strongly supported by present-day scientists like Richard Dawkins and Stephen Jay Gould - assumes we are at the mercy of our genes, which we inherit largely unchanged from our parents, except for rare random mutations which accumulate and lead to change over evolutionary time.

Those genes are coded in the chromosomes of the sperm and egg cells of the parents, and so only changes to those two types of cell have any chance of being passed down to the parents' offspring. Any changes, accidents, or surgery to the rest of the parents' bodies are not transmitted to the newborn.

The theory of inheritance of acquired characteristics - if you build up your muscles your kids will be born with a propensity toward great strength - on the other hand, favored by Jean Lamarck in the nineteenth century, was brought down by nineteenth-century science. But now, as this challenging and thrilling book shows, it looks as though, at least for certain structures in the body's immune system, Lamarck may have been right after all.

Based on their own ground-breaking work over the past two decades, as well as that of other molecular biologists, Steele, Lindley, and Blanden argue that for one adaptive body system there is strong molecular genetic evidence that aspects of acquired immunities developed by parents in their own lifetime can be passed on to their offspring.
Notes: Includes bibliographical references (p. 262-271) and index.