Biomarkers in kidney disease
By: edited by Charles L. Edelstein
Contributors: ScienceDirect (Online service)
Publisher: Academic; Academic Press
Published: 2010
Place of publication: London
Language: eng
Format: [electronic resource] /
ISBN-13: 9780123756725
Subjects: Biochemical markers; Kidneys; Diseases; Molecular diagnosis
Description: A biomarker is a molecule that is measured as a marker of normal biological processes, disease processes or the response to a diagnostic or therapeutic intervention. Kidney diseases like acute kidney injury, chronic kidney disease, diabetic nephropathy, glomerular disease, renal cancer and preeclampsia still have a high morbidity. Measurement of biomarkers in the blood or urine that detect patients at risk of kidney diseases or that detect kidney diseases in the earliest stage may ultimately result in preventative or earlier or more effective treatments for kidney diseases. Biomarkers of Kidney Disease&nbsp;reviews the basic and clinical research on biomarkers of the common kidney diseases including acute kidney injury, chronic kidney disease, renal cancer, diabetic nephropathy, glomerular disease and preeclampsia. The characteristics of an ideal biomarker of kidney diseases and statistical analysis of biomarker studies is detailed. The latest techniques for biomarker detection like metabolomics and proteomics is covered in the book. This comprehensive book details the latest advances made in the field of biomarker research and development in kidney diseases. The book is an ideal companion for those interested in biomarker research and development, proteomics and metabolomics, kidney diseases, statistical analysis, transplantation and preeclampsia. * Presents a comprehensive, translational source for all aspects of renal biomarkers in one reference work * Experts in renal disease biomarkers (from all areas of academic and medical research) take readers from the bench research (cellular and molecular mechanism) to new therapeutic approaches.
Notes: Electronic reproduction. Amsterdam : Elsevier Science & Technology, 2010. Mode of access: World Wide Web. System requirements: Web browser. Title from title screen (viewed on Sep. 27, 2010). Access may be restricted to users at subscribing institutions.
Table of contents: title: Characteristics of an Ideal Biomarker of Kidney Diseases / Prasad Devarajan and Michael R. Bennett; title: Statistical Analysis of Biomarker Studies / Chirag Parikh and Heather Thiessen Philbrook; title: Metabolonomics: Screening for Biomarkers of Kidney Disease / Uwe Christians, Jelena Klawitter, Jost Klawitter, and Jeska Albuisson; title: Proteomics: Screening for Biomarkers of Kidney Disease / Uwe Christians, Jelena Klawitter, Jost Klawitter, and Jeska Albuisson; title: Biomarkers of Acute Kidney Injury / Charles Edelstein and Sarah Faubel; title: Biomarkers of Kidney Transplant Rejection / Alkesh Jani; title: Cystatin C-A Biomarker of Risk in Chronic Kidney Disease / Anders Grubb; title: Prognostic Biomarkers in Renal Cell Cancer / Roz Banks and Naveen Vasudev; title: Biomarkers in Diabetic Nephropathy / Jon Klein and Michael L. Merchant; title: Biomarkers in Glomerular Diseases / John M. Arthur; title: Diagnostic Markers and Therapeutic Approaches in Preeclampsia / S. Ananth Karumanchi and Ana Sofia Cerdeira.