Dopamine, Volume 21 (Handbook of Chemical Neuroanatomy)
Contributors: S.B. Dunnett (Editor); M. Bentivoglio (Editor); A. Björklund (Editor); T. Hökfelt (Editor)
Publisher: Elsevier Science
Published: February 17, 2005
Language: eng
Format: Hardcover
Number of pages: 608
ISBN-13: 9780444517784
Subjects: Neurology & clinical neurophysiology; Neurosciences; Medical / Nursing; Medical; Neuroscience; Medical / Neuroscience; Pharmacology
First sentence: The substantia nigra (SN) was observed in the human brain as a collection of pigmented cells lying dorsal to the cerebral peduncle by Vicq d'Azir, who described it in 1786 as 'locus niger crurum cerebri', and soon after by Sommerring (1788) whose name was linked to this structure (see, for example, Fig. 1).
Description: Dopamine is a major neurotransmitter of the brain involved in the control of movement, emotion, and cognition; disturbance in dopamine function is associated with disorders like Parkinsons disease, schizophrenia and attention deficit hyperactivity disorder. This volume of the Handbook of Chemical Neuroanatomy provides a series of in depth critical reviews of our present understanding of the most important aspects of dopamines organisation and disturbed function in the animal and human brain.