Red Cell Membrane Transport in Health and Disease
By: edited by Ingolf Bernhardt, J. Clive Ellory
Contributors: Ellory, J. Clive
Publisher: Springer Berlin Heidelberg
Published: 2003
Place of publication: Berlin, Heidelberg
Language: eng
Format: [electronic resource] /
Number of pages: 748
ISBN-13: 9783642079207; 9783662051818
Subjects: Medicine; Life sciences; Physics; Hematology
Description: This book describes our current understanding of the transport of ions, amino acids, nucleosides, sugars, water and gases across the red blood cell membrane. It also outlines the necessary theoretical background to understand the dynamics of membrane constituents together with the mechanisms of transport pathways (pumps, channels, carriers/cotransporters, residual passive permeability). Separate chapters describe our present ideas about membrane and metabolic disorders as well as red blood cell diseases like malaria, sickle cell disease, and hypertension. The latest findings are explained on the basis of a historical review and well-established principles. The book and its chapters are thus structured in a manner that makes the material accessible to beginners in the field of red blood cell physiology and biophysics. Active researchers will also benefit from this carefully organized compilation.
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Table of contents: title: Lipid dynamics and transport; title: Red cell shape and biomechanics; title: Lipid disorders in diseases; title: Passive membrane permeability for ions and membrane potential; title: Na-pump; title: Ion channels; title: Osmolyte channels; title: Ion cotransport systems; title: Band 3-mediated transport; title: Amino acid transport; title: Nucleoside transport; title: Glucose transport; title: Ca-transport; title: Mg-transport; title: Trace metal transport; title: Monocarboxylate and other organic anion transport; title: Water permeability; title: Gas transport; title: Stomatocytosis and related transport defects; title: Metabolic disorders and oxidative damage; title: Sickle cell disease; title: Malaria.-Hypertension; title: Disorders involving Band-3; title: Amino acid transport in disease; title: Transgenic models of red cell disorders; title: Red cell aging and storage; title: Membrane transport in sheep red cells (as model cells); title: Comparative physiology of membrane transport.