Molecular targeting and signal transduction
By: edited by Rakesh Kumar.
Contributors: Kumar, Rakesh, Ph. D.
Series: Cancer treatment and research -- v. 119
Publisher: Kluwer Academic Publishers; Springer
Published: 2004
Place of publication: Boston
Language: eng
Number of pages: 331
Subjects: Cancer cells; Drug targeting; Cellular signal transduction; Neoplasms -- therapy; Signal Transduction; Genetic Markers; Receptor Protein-Tyrosine Kinases -- genetics; Receptors, Growth Factor -- genetics
Notes: Includes bibliographical references and index.
Table of contents: title: Biology of the epidermal growth factor receptor family.; title: Integrin signaling in cancer.; title: Regulators of vascular endothelial growth factor expression in cancer.; title: Integrin-linked kinase (ILK) in combination molecular targeting.; title: p21-activated kinase 1: an emerging therapeutic target.; title: Basis and importance of Src as a target in cancer.; title: Therapeutic targeting of the receptor tyrosine kinase met.; title: Nuclear factor -kB activation mediates cellular transformation, proliferation, invasion, angiogenesis and metastasis of cancer.; title: The p53 pathway: targets for the development of novel cancer therapeutics.; title: Runx protein signaling in human cancers.; title: Signal transduction mediated by Cyclin D1: from mitogens to cell proliferation: a molecular target with therapeutic potential.; title: Signal transduction pathways in Bcr-Abl transformed cells.; title: Estrogen receptors and anti-estrogen therapies.; title: Targeting endothelin axis in cancer.; title: km23: a novel TGF[Beta] signaling target altered in ovarian cancer.