Tandem repeats in genes, proteins, and disease
Subtitle: methods and protocols
By: edited by Danny M. Hatters, Department of Biochemistry  and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, Australia, Anthony J. Hannan, Florey Institute of Neuroscience and Mental Health, Melbourne Brain Centre, University of Melbourne, Parkville, VIC, Australia
Contributors: Springer Science+Business Media
Series: Methods in molecular biology -- 1017; Springer protocols; Methods in molecular biology (Clifton, N.J.) -- v. 1017.; Springer protocols (Series)
Publisher: Humana Press
Published: 2013
Place of publication: New York
Language: eng
Number of pages: 258
ISBN-13: 9781627034371; 9781627034388
Copyright date: 2013
Subjects: Nucleotides; Laboratory manuals; Genetics; Tandem Repeat Sequences; Laboratory Manuals; Disease; Genetic Phenomena
Notes: Includes bibliographical references and index.
Table of contents: title: Longitudinal imaging and analysis of neurons expressing polyglutamine-expanded proteins  -- Andrey S. Tsvetkov, D. Michael Ando, and Steven Finkbeiner; title: Atomic force microscopy assays for evaluating polyglutamine aggregation in solution and on surfaces  -- Kathleen A. Burke and Justin Legleiter; title: Morphometric analysis of Huntington's disease neurodegeneration in Drosophila  -- Wan Song ... [et al.]; title: Size analysis of polyglutamine protein aggregates using fluorescence detection in an analytical ultracentrifuge  -- Saskia Polling, Danny M. Hatters, and Yee-Foong Mok; title: Method for the incremental expansion of polyglutamine repeats in recombinant proteins  -- Amy L. Robertson and Stephen P. Bottomley; title: Pulse shape analysis (PulSA) to track protein translocalization in cells by flow cytometry : applications for polyglutamine aggregation  -- Yasmin M. Ramdzan, Rebecca Wood, and Danny M. Hatters; title: Characterizing social behavior in genetically targeted mouse models of brain disorders  -- Emma L. Burrows and Anthony J. Hannan; title: PCR amplification and sequence analysis of GC-rich sequences : aristaless-related homeobox example  -- May H. Tan, Jozef Gécz, and Cheryl Shoubridge; title: Challenges of "Sticky" co-immunoprecipitation : polyalanine tract protein-protein interactions  -- T.R. Mattiske ... [et al.]; title: Molecular pathology of polyalanine expansion disorders : new perspectives from mouse models  -- James N. Hughes and Paul Q. Thomas; title: Yeast as a platform to explore polyglutamine toxicity and aggregation  -- Martin L. Duennwald; title: Immuno-based detection assays to quantify distinct mutant huntingtin conformations in biological samples  -- Gregor P. Lotz and Andreas Weiss; title: Modeling and analysis of repeat RNA toxicity in Drosophila  -- S.E. Samaraweera ... [et al.]; title: Analyzing modifiers of protein aggregation in C. elegans by native agarose gel electrophoresis  -- Mats Holmberg and Ellen A.A. Nollen; title: Kinetic analysis of aggregation data  -- Regina M. Murphy; title: Bioinformatics method for identifying Q/N-rich prion-like domains in proteins  -- Eric D. Ross ... [et al.]; title: Detecting soluble polyQ oligomers and investigating their impact on living cells using split-GFP  -- Patrick Lajoie and Erik Lee Snapp; title: Cell biological approaches to investigate polyglutamine-expanded AR metabolism -- Lori J. Cooper and Diane E. Merry.