Radical-mediated protein oxidation
Subtitle: from chemistry to medicine
By: Michael J. Davies and Roger T. Dean.
Contributors: Dean, R. T.
Series: Oxford science publications
Publisher: Oxford University Press
Published: 1997
Place of publication: Oxford; New York
Language: eng
Number of pages: 443
Subjects: Proteins -- Oxidation.; Free radicals (Chemistry) -- Pathophysiology.; Free radicals (Chemistry) -- Physiological effect.
Description: Protein oxidation by free radicals is thought to play a major role in many oxidative processes within cells, and is implicated in human disease, carcinogenesis, and ageing. This unique and comprehensive volume brings together up-to-date information on the oxidation of amino acids, peptides, and proteins by free radicals and discusses the roles of such processes in biological systems.

Topics include: the chemistry of amino acid and protein oxidation; the biochemical consequences of these reactions; the role of protein oxidation in normal physiology; the potential importance of protein oxidation in human health - including ageing, heart disease, cancer, inflammation, and neurodegenerative diseases - and the possible prevention of such processes by antioxidants and other protective strategies.
Notes: Includes bibliographical references (p. [246]-430) and index.