Apoptosis and autoimmunity
Subtitle: [from mechanisms to treatments]
By: edited by M. Hermann and J.R. Kalden
Contributors: Herrmann, M. Dr; Kalden, J. R.
Publisher: Wiley-VCH
Published: 2003
Place of publication: Weinheim
Language: eng
Number of pages: 381
Subjects: Apoptosis; Autoimmunity; Autoimmune diseases
Description: This is the first comprehensive book about the relationship between apoptosis and autoimmune diseases. It offers a unique up-to-date overview on research results on the defective execution of apoptosis and the incomplete clearance of apoptotic cells. The molecular and cellular mechanisms involved are described in detail. As a possible consequence of apoptotic dysfunction, the development of severe autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus) is discussed. An outlook on future research topics includes the evaluation of novel therapeutic strategies.
Notes: Subtitle from cover

Includes bibliographical references and index
Table of contents: title: Part 1. General feature of apoptosis.; title: Part 1. General feature of apoptosis. -- Keith Elkon; title: Part 1. General feature of apoptosis. -- Keith Elkon -- Saquib Lakhani, Binfeng Lu and Richard A. Flavell -- Part 2. Clearance of apoptotic cells.; title: Part 1. General feature of apoptosis. -- Keith Elkon -- Saquib Lakhani, Binfeng Lu and Richard A. Flavell -- Part 2. Clearance of apoptotic cells. -- Reinhard E. Voll ... [et al.]; title: Part 1. General feature of apoptosis. -- Keith Elkon -- Saquib Lakhani, Binfeng Lu and Richard A. Flavell -- Part 2. Clearance of apoptotic cells. -- Reinhard E. Voll ... [et al.] -- Dror Mevorach; title: Part 1. General feature of apoptosis. -- Keith Elkon -- Saquib Lakhani, Binfeng Lu and Richard A. Flavell -- Part 2. Clearance of apoptotic cells. -- Reinhard E. Voll ... [et al.] -- Dror Mevorach -- Patrizia Rovere-Querini; title: Part 1. General feature of apoptosis. -- Keith Elkon -- Saquib Lakhani, Binfeng Lu and Richard A. Flavell -- Part 2. Clearance of apoptotic cells. -- Reinhard E. Voll ... [et al.] -- Dror Mevorach -- Patrizia Rovere-Querini -- Véronique Rigot and Giovanna Chimini; title: Part 1. General feature of apoptosis. -- Keith Elkon -- Saquib Lakhani, Binfeng Lu and Richard A. Flavell -- Part 2. Clearance of apoptotic cells. -- Reinhard E. Voll ... [et al.] -- Dror Mevorach -- Patrizia Rovere-Querini -- Véronique Rigot and Giovanna Chimini -- Christopher D. Gregory and Andrew Devitt -- Part 3. Autoimmunity caused by defective execution of apoptosis or defective clearance of apoptosis cells.; title: Part 1. General feature of apoptosis. -- Keith Elkon -- Saquib Lakhani, Binfeng Lu and Richard A. Flavell -- Part 2. Clearance of apoptotic cells. -- Reinhard E. Voll ... [et al.] -- Dror Mevorach -- Patrizia Rovere-Querini -- Véronique Rigot and Giovanna Chimini -- Christopher D. Gregory and Andrew Devitt -- Part 3. Autoimmunity caused by defective execution of apoptosis or defective clearance of apoptosis cells. -- Frédérik Rieux-Laucat, Franc̲oise le Deist and Alain Fischer; title: Part 1. General feature of apoptosis. -- Keith Elkon -- Saquib Lakhani, Binfeng Lu and Richard A. Flavell -- Part 2. Clearance of apoptotic cells. -- Reinhard E. Voll ... [et al.] -- Dror Mevorach -- Patrizia Rovere-Querini -- Véronique Rigot and Giovanna Chimini -- Christopher D. Gregory and Andrew Devitt -- Part 3. Autoimmunity caused by defective execution of apoptosis or defective clearance of apoptosis cells. -- Frédérik Rieux-Laucat, Franc̲oise le Deist and Alain Fischer -- Hanns-Martin Lorenz; title: Part 1. General feature of apoptosis. -- Keith Elkon -- Saquib Lakhani, Binfeng Lu and Richard A. Flavell -- Part 2. Clearance of apoptotic cells. -- Reinhard E. Voll ... [et al.] -- Dror Mevorach -- Patrizia Rovere-Querini -- Véronique Rigot and Giovanna Chimini -- Christopher D. Gregory and Andrew Devitt -- Part 3. Autoimmunity caused by defective execution of apoptosis or defective clearance of apoptosis cells. -- Frédérik Rieux-Laucat, Franc̲oise le Deist and Alain Fischer -- Hanns-Martin Lorenz -- Yuji Yamanishi amd Gary S. Firestein; title: Part 1. General feature of apoptosis. -- Keith Elkon -- Saquib Lakhani, Binfeng Lu and Richard A. Flavell -- Part 2. Clearance of apoptotic cells. -- Reinhard E. Voll ... [et al.] -- Dror Mevorach -- Patrizia Rovere-Querini -- Véronique Rigot and Giovanna Chimini -- Christopher D. Gregory and Andrew Devitt -- Part 3. Autoimmunity caused by defective execution of apoptosis or defective clearance of apoptosis cells. -- Frédérik Rieux-Laucat, Franc̲oise le Deist and Alain Fischer -- Hanns-Martin Lorenz -- Yuji Yamanishi amd Gary S. Firestein -- Thomas D. Beyer ... [et al.] -- Part 4. Immunogenicity of apoptotic cells.; title: Part 1. General feature of apoptosis. -- Keith Elkon -- Saquib Lakhani, Binfeng Lu and Richard A. Flavell -- Part 2. Clearance of apoptotic cells. -- Reinhard E. Voll ... [et al.] -- Dror Mevorach -- Patrizia Rovere-Querini -- Véronique Rigot and Giovanna Chimini -- Christopher D. Gregory and Andrew Devitt -- Part 3. Autoimmunity caused by defective execution of apoptosis or defective clearance of apoptosis cells. -- Frédérik Rieux-Laucat, Franc̲oise le Deist and Alain Fischer -- Hanns-Martin Lorenz -- Yuji Yamanishi amd Gary S. Firestein -- Thomas D. Beyer ... [et al.] -- Part 4. Immunogenicity of apoptotic cells. -- Lars Jenne and Birthe Sauter; title: Part 1. General feature of apoptosis. -- Keith Elkon -- Saquib Lakhani, Binfeng Lu and Richard A. Flavell -- Part 2. Clearance of apoptotic cells. -- Reinhard E. Voll ... [et al.] -- Dror Mevorach -- Patrizia Rovere-Querini -- Véronique Rigot and Giovanna Chimini -- Christopher D. Gregory and Andrew Devitt -- Part 3. Autoimmunity caused by defective execution of apoptosis or defective clearance of apoptosis cells. -- Frédérik Rieux-Laucat, Franc̲oise le Deist and Alain Fischer -- Hanns-Martin Lorenz -- Yuji Yamanishi amd Gary S. Firestein -- Thomas D. Beyer ... [et al.] -- Part 4. Immunogenicity of apoptotic cells. -- Lars Jenne and Birthe Sauter -- Angelo A. Manfredi -- Part 5. "Altered self" in dying cells.; title: Part 1. General feature of apoptosis. -- Keith Elkon -- Saquib Lakhani, Binfeng Lu and Richard A. Flavell -- Part 2. Clearance of apoptotic cells. -- Reinhard E. Voll ... [et al.] -- Dror Mevorach -- Patrizia Rovere-Querini -- Véronique Rigot and Giovanna Chimini -- Christopher D. Gregory and Andrew Devitt -- Part 3. Autoimmunity caused by defective execution of apoptosis or defective clearance of apoptosis cells. -- Frédérik Rieux-Laucat, Franc̲oise le Deist and Alain Fischer -- Hanns-Martin Lorenz -- Yuji Yamanishi amd Gary S. Firestein -- Thomas D. Beyer ... [et al.] -- Part 4. Immunogenicity of apoptotic cells. -- Lars Jenne and Birthe Sauter -- Angelo A. Manfredi -- Part 5. "Altered self" in dying cells. -- Antony Rosen and Livia Casciola-Rosen; title: Part 1. General feature of apoptosis. -- Keith Elkon -- Saquib Lakhani, Binfeng Lu and Richard A. Flavell -- Part 2. Clearance of apoptotic cells. -- Reinhard E. Voll ... [et al.] -- Dror Mevorach -- Patrizia Rovere-Querini -- Véronique Rigot and Giovanna Chimini -- Christopher D. Gregory and Andrew Devitt -- Part 3. Autoimmunity caused by defective execution of apoptosis or defective clearance of apoptosis cells. -- Frédérik Rieux-Laucat, Franc̲oise le Deist and Alain Fischer -- Hanns-Martin Lorenz -- Yuji Yamanishi amd Gary S. Firestein -- Thomas D. Beyer ... [et al.] -- Part 4. Immunogenicity of apoptotic cells. -- Lars Jenne and Birthe Sauter -- Angelo A. Manfredi -- Part 5. "Altered self" in dying cells. -- Antony Rosen and Livia Casciola-Rosen -- Carlos A. Casiano ... [et al.]; title: Part 1. General feature of apoptosis. -- Keith Elkon -- Saquib Lakhani, Binfeng Lu and Richard A. Flavell -- Part 2. Clearance of apoptotic cells. -- Reinhard E. Voll ... [et al.] -- Dror Mevorach -- Patrizia Rovere-Querini -- Véronique Rigot and Giovanna Chimini -- Christopher D. Gregory and Andrew Devitt -- Part 3. Autoimmunity caused by defective execution of apoptosis or defective clearance of apoptosis cells. -- Frédérik Rieux-Laucat, Franc̲oise le Deist and Alain Fischer -- Hanns-Martin Lorenz -- Yuji Yamanishi amd Gary S. Firestein -- Thomas D. Beyer ... [et al.] -- Part 4. Immunogenicity of apoptotic cells. -- Lars Jenne and Birthe Sauter -- Angelo A. Manfredi -- Part 5. "Altered self" in dying cells. -- Antony Rosen and Livia Casciola-Rosen -- Carlos A. Casiano ... [et al.] -- Alessandra Amendola and Mauro Piacentini; title: Part 1. General feature of apoptosis. -- Keith Elkon -- Saquib Lakhani, Binfeng Lu and Richard A. Flavell -- Part 2. Clearance of apoptotic cells. -- Reinhard E. Voll ... [et al.] -- Dror Mevorach -- Patrizia Rovere-Querini -- Véronique Rigot and Giovanna Chimini -- Christopher D. Gregory and Andrew Devitt -- Part 3. Autoimmunity caused by defective execution of apoptosis or defective clearance of apoptosis cells. -- Frédérik Rieux-Laucat, Franc̲oise le Deist and Alain Fischer -- Hanns-Martin Lorenz -- Yuji Yamanishi amd Gary S. Firestein -- Thomas D. Beyer ... [et al.] -- Part 4. Immunogenicity of apoptotic cells. -- Lars Jenne and Birthe Sauter -- Angelo A. Manfredi -- Part 5. "Altered self" in dying cells. -- Antony Rosen and Livia Casciola-Rosen -- Carlos A. Casiano ... [et al.] -- Alessandra Amendola and Mauro Piacentini -- Paul J. Utz -- Part 6. The role of DNA binding proteins for systemic autoimmunity.; title: Part 1. General feature of apoptosis.-- Keith Elkon-- Saquib Lakhani, Binfeng Lu and Richard A. Flavell-- Part 2. Clearance of apoptotic cells.-- Reinhard E. Voll ... [et al.]-- Dror Mevorach-- Patrizia Rovere-Querini-- Véronique Rigot and Giovanna Chimini-- Christopher D. Gregory and Andrew Devitt-- Part 3. Autoimmunity caused by defective execution of apoptosis or defective clearance of apoptosis cells.-- Frédérik Rieux-Laucat, Franc̲oise le Deist and Alain Fischer-- Hanns-Martin Lorenz-- Yuji Yamanishi amd Gary S. Firestein-- Thomas D. Beyer ... [et al.]-- Part 4. Immunogenicity of apoptotic cells.-- Lars Jenne and Birthe Sauter-- Angelo A. Manfredi-- Part 5. "Altered self" in dying cells.-- Antony Rosen and Livia Casciola-Rosen-- Carlos A. Casiano ... [et al.]-- Alessandra Amendola and Mauro Piacentini-- Paul J. Utz-- Part 6. The role of DNA binding proteins for systemic autoimmunity.-- Keith Jürgen W.C. Dieker, Johan van der Vlag and Jo H.M. Berden