Chromatic visual evoked potentials in offspring of women with thyroid disease in pregnancy.
Published: 2007
Language: eng
Number of pages: 224
ISBN-13: 9780494273722
Description: Animal literature has revealed that gestational thyroid hormone (TH) deficits lead to excess S-cones and a deficiency of M-cones. Because cones are essential for colour vision, it is hypothesized that gestational TH deficits in humans lead to abnormalities in colour processing. Chromatic Visual Evoked Potentials (cVEPs) were measured in infants of women with hypothyroidism in pregnancy (HYPO) (n = 23), infants of women taking antithyroid drugs (ATDs) for hyperthyroidism in pregnancy (HYPER) (n = 9) and controls (n = 21). HYPO and HYPER groups represent infants with TH insufficiencies in early and late gestation, due to insufficient maternal TH levels and the effect of ATDs on fetal thyroid function, respectively. Compared to controls, HYPO/HYPER groups had longer mean latencies to stimuli modulating the L/M-cone pathway and shorter latencies to S-cone modulating stimuli (non-significant). While these trends are suggestive of underlying L/M cone deficits, future studies in this field are required.
Notes: Source: Masters Abstracts International, Volume: 45-06, page: 3066.

Thesis (M.Sc.)--University of Toronto, 2007.

Electronic version licensed for access by U. of T. users.

ROBARTS MICROTEXT copy on microfiche.