Bioinformatics and Molecular Evolution
Contributors: Attwood, Teresa K.
Publisher: John Wiley & Sons
Published: 2009
Place of publication: Chichester
Language: eng
Format: [electronic resource]
Number of pages: 398
ISBN-13: 9781444311181
Subjects: Molecular evolution
Description: In the current era of complete genome sequencing, Bioinformatics and Molecular Evolution provides an up-to-date and comprehensive introduction to bioinformatics in the context of evolutionary biology. This accessible text:.:.; provides a thorough examination of sequence analysis, biological databases, pattern recognition, and applications to genomics, microarrays, and proteomics.:.; emphasizes the theoretical and statistical methods used in bioinformatics programs in a way that is accessible to biological science students.:.; places bioinformatics in the context of evolutionary biology, includ.
Notes: Description based on print version record.
Table of contents: title: Bioinformatics and Molecular Evolution; Full Contents; Preface; 1 Introduction: The revolution in biological information; 1.1 DATA EXPLOSIONS; 1.2 GENOMICS AND HIGH-THROUGHPUT TECHNIQUES; 1.3 WHAT IS BIOINFORMATICS?; 1.4 THE RELATIONSHIP BETWEEN POPULATION GENETICS, MOLECULAR EVOLUTION, AND BIOINFORMATICS; SUMMARY; 2 Nucleic acids, proteins, and amino acids; 2.1 NUCLEIC ACID STRUCTURE; 2.2 PROTEIN STRUCTURE; 2.3 THE CENTRAL DOGMA; 2.4 PHYSICO-CHEMICAL PROPERTIES OF THE AMINO ACIDS AND THEIR IMPORTANCE IN PROTEIN FOLDING; BOX 2.1 Polymerase chain reaction (PCR).; title: 2.5 VISUALIZATION OF AMINO ACID PROPERTIES USING PRINCIPAL COMPONENT ANALYSIS2.6 CLUSTERING AMINO ACIDS ACCORDING TO THEIR PROPERTIES; BOX 2.2 Principal component analysis in more detail; SUMMARY; 3 Molecular evolution and population genetics; 3.1 WHAT IS EVOLUTION?; 3.2 MUTATIONS; 3.3 SEQUENCE VARIATION WITHIN AND BETWEEN SPECIES; 3.4 GENEALOGICAL TREES AND COALESCENCE; 3.5 THE SPREAD OF NEW MUTATIONS; 3.6 NEUTRAL EVOLUTION AND ADAPTATION; BOX 3.1 Th.