Handbook of drug screening
By: edited by Ramakrishna Seethala, Litao Zhang.
Contributors: Seethala, Ramakrishna, 1947-; Zhang, Litao.
Edition: 2nd ed.
Series: Drugs and the pharmaceutical sciences -- 196; Drugs and the pharmaceutical sciences -- 196.
Publisher: Informa Healthcare USA
Published: 2009
Place of publication: New York
Language: eng
ISBN-13: 9781420061680
Subjects: Drug development -- Handbooks, manuals, etc; Drugs -- Testing -- Handbooks, manuals, etc; Drug Evaluation, Preclinical -- methods
Genres: Handbooks, manuals, etc
Notes: Includes bibliographical references and index.
Table of contents: title: Key factors for successful high throughput screening; title: Critical components in high throughput screening : challenges and new trends; title: Hit to probe to lead optimization strategies : a biology perspective to conquer the valley of death; title: Signal detection platforms for screening in drug discovery; title: Proteomic analysis in drug discovery; title: Screening and characterization of g-protein-coupled receptor ligands for drug discovery; title: Nuclear hormone receptor screening in drug discovery; title: Emerging novel high-throughput screening technologies for cell-based assays; title: In-vitro strategies for ion channel screening in drug discovery; title: Wheat from chaff : general and mechanistic triage of screening hits for enzyme targets; title: Protein kinases and phosphatases; title: Micro rna strategies in drug discovery; title: Strategies for screening of biologic therapeutics; title: Cryopreserved cells in functional cell-based hts assays; title: High-content screening with a special emphasis on cytotoxicity and cell health measurements; title: Effective application of drug metabolism & pharmacokinetics in drug discovery; title: Compound management for drug discovery : an overview; title: Practical approach to quantitative high throughput screening; title: Enabling the large scale analysis of quantitative high throughput screening data; title: Application of nanobiotechnologies for drug discovery.