Kinase inhibitors
Subtitle: methods and protocols
By: edited by Bernhard Kuster
Series: Methods in molecular biology -- 795; Springer protocols; Methods in molecular biology (Clifton, N.J.) -- v. 795.; Springer protocols
Publisher: Humana Press; Springer
Published: 2012
Place of publication: New York
Language: eng
Number of pages: 256
ISBN-13: 9781617793363; 9781617793370
Subjects: Protein Kinase Inhibitors; Methods; Protein kinases; Molecular Targeted Therapy; Laboratory Manuals; Inhibitors
Notes: Includes bibliographical references and index.
Table of contents: title: Targeting cancer with small-molecular-weight kinase inhibitors / Doriano Fabbro ... [et al.]; title: Small-molecule protein and lipid kinase inhibitors in inflammation and specific models for their evaluation / Matthias Gaestel and Alexey Kotlyarov; title: Measuring the activity of leucine-rich repeat kinase 2 : a kinase involved in Parkinson's disease / Byoung Dae Lee ... [et al.]; title: Measuring P13K lipid kinase activity / Elisa Ciraolo, Alessia Perino, and Emilio Hirsch; title: A fluorescence polarization assay for the discovery of inhibitors of the polo-box domain of polo-like kinase 1 / Wolfgang Reindl, Klause Strebhardt, and Thorsten Berg; title: Assessment of hepatotoxicity potential of drug candidate molecules including kinase inhibitors by hepatocyte imaging assay technology and bile flux imaging assay technology / Jinghai J. Xu ... [et al.]; title: Kinase inhibitor selectivity profiling using differential scanning fluorimetry / Oleg Fedorov, Frank H. Niesen, and Stefan Knapp; title: Chemoproteomic characterization of protein kinase inhibitors using immobilized ATP / James S. Duncan, Timothy A.J. Haystead, and David W. Litchfield.; title: Proteome-wide identification of staurosporine-binding kinases using capture coumpound mass spectrometry / Jenny J. Fischer, Olivia Y. Graebner (neé Baessler), and Mathias Dreger; title: Affinity pruification of proteins binding to kinase inhibitors immobilized on self-assembling monolayers / Marcus Bantscheff, Scott Hobson, and Bernhard Kuster; title: Kinase inhibitor profiling using chemoproteomics / Markus Schirle ... [et al.]; title: Covalent cross-linking of kinases with their corresponding peptide substrates / Alexander V. Statsuk and Kevan M. Shokat; title: Receptor tyrosine kinase inhibitor profiling using bead-based multiplex sandwich immunoassays / Oliver Pötz ... [et al.]; title: Monitoring phosphoproteomic response to targeted kinase inhibitors using reverse-phase protein microarrays / Gabriela Lavezzari and Mark R. Lackner; title: Measuring phosphorylation-specific changes in response to kinase inhibitors in mammalian cells using quantitative proteomics / Nurhan Özlü, Marc Kirchner, and Judith Jebanathirajah Steen; title: Investigation of acquired resistance to EGFR-targeted therapies in lung cancer using cDNA microarrays / Kian Kani, Rafaella Sordella, and Parag Mallick.