Bioinformatics and functional genomics
By: Jonathan Pevsner.
Edition: 2nd ed.
Publisher: Wiley
Published: 2009
Place of publication: Hoboken, N.J
Language: eng
Number of pages: 951
ISBN-13: 9780470085851
Subjects: Genomics; Bioinformatics; Proteomics; Computational Biology -- methods; Genetic Techniques
Description: The second edition of this book has been thoroughly updated and enhanced. The text continues to offer the most broad-based introduction to this explosive new discipline, combining theoretical context with practical applications. The first third of this book covers bioinformatics, a new field at the interface of the ongoing revolutions in molecular biology and computers. A focus of this new discipline is the use of computer databases and computer algorithms to study proteins and genes, including sequence alignment, database searches, and phylogeny. The middle third of this book focuses on functional genomics including approaches such as gene expression profiling and proteomics that are used to study cellular function. The last third of the book is on genomics which is the study of the collection of DNA that comprises an organism, using the tools of bioinformatics. This portion of the book spans the tree of life from viruses to prokaryotes and eukaryotes, including a description of the human genome in health and disease.
Notes: Includes bibliographical references and index.
Table of contents: title: Access to sequence data and literature information; title: Pairwise sequence alignment; title: Basic local alignment search tool (BLAST); title: Advanced database searching; title: Multiple sequence alignment; title: Molecular phylogeny and evolution; title: Bioinformatic approaches to ribonucleic acid (RNA); title: Gene expression : microarray data analysis; title: Protein analysis and proteomics; title: Protein structure; title: Functional genomics; title: Completed genomes; title: Completed genomes : viruses; title: Completed genomes : bacteria and archaea; title: The eukaryotic chromosome; title: Eukaryotic genomes : fungi; title: Eukaryotic genomes : from parasites to primates; title: Human genome; title: Human disease.