Therapeutic oligonucleotides
Subtitle: transcriptional and translational strategies for silencing gene expression
By: edited by Y.S. Cho-chung, Alan M. Gewirtz, and Cy A. Stein.
Contributors: Cho-Chung, Yoon S.; Gewirtz, A. M.; Stein, Cy A.; New York Academy of Sciences.
Series: Annals of the New York Academy of Sciences ;; v. 1058
Publisher: New York Academy of Sciences
Published: 2005
Place of publication: New York
Language: eng
Subjects: Oligonucleotides -- Therapeutic use -- Congresses; Oligonucleotides -- therapeutic use -- Congresses
Genres: Congresses.
Notes: Includes bibliographical references and index.
Table of contents: title: A phase I pharmacokinetic (PK) and pharmacodynamic (PD) study of OGX-011, a 2'methoxyethyl phosphorothioate antisense to clusterin, in patients with prostate cancer prior to radical prostatectomy / M. Gleave; title: Recognition of chromosomal DNA in human cells by peptide nucleic acids and small duplex RNAs / David R. Corey; title: Design and development of thermolytic DNA oligonucleotide prodrugs / Andrzej Grajkowski ... [et al.]; title: Rationally targeted, conformationally constrained, oxetane-modified oligonucleotides demonstrate efficient gene-silencing activity in a cellular system / J. B. Opalinska and A. M. Gewirtz; title: In vivo potentialities of EWS-FLI-1 targeted antisense oligonucleotides-nanospheres complexes / Andrei Maksimenko ... [et al.]; title: Endo-porter: a novel reagent for safe, effective delivery of substances into cells / James E. Summerton; title: Tumor reversion: protein kinase a isozyme switching / Yoon S. Cho-chung and Maria V. Nesterova; title: Therapeutic potential of oligonucleotides expressing immunosuppressive TTAGGG motifs / Dennis M. Klinman ... [et al.]; title: Breaking tolerance to tumors with dendritic cell-based immunotherapy / Ines Mende and Edgar G. Engleman; title: Development of resistance to RNAi in mammalian cells / Zhi-Ming Zheng, Shuang Tang, and Mingfang Tao; title: The development of bioactive triple helix forming oligonucleotides / Michael M. Seidman; title: Transcription factor decoys: a new model for disease intervention / Michael J. Mann; title: DNA damage produced by 125I-triplex forming oligonucleotides as a measure of their succesful delivery into cell nuclei / Irina V. Panyutin; title: Targeted genome modification via triple helix formation / Jennifer M. Kalish And Peter M. Glazer; title: Identification of promoters bound by cJUN/ATF2 during rapid large-scale gene activation following genotoxic stress using siRNA / D. Mercola; title: Application of expression genomics for predicting treatment response in cancer / Khew-Voon Chin ... [et al.]; title: Stability regulation of mRNA and the control of gene expression / Chris Cheadle ... [et al.]; title: Novel MDM2 p53-independent functions identified through RNA silencing technologies / Zhuo Zhang ... [et al.]; title: Application of XIAP antisense to cancer and other proliferative disorders: development of AEG35156/ GEM640 / Eric C. Lacasse ... [et al.]; title: Induction of apoptosis by G3139 in melanoma cells / Luba Benimetskaya ... [et al.]; title: Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy / Victor E. Marquez ... [et al.]; title: Chemoprevention with protein kinase A RI{alpha} antisense in DMBA-mammary carcinogenesis / Maria V. Nesterova and Yoon S. Cho-chung.