Batten disease
Subtitle: diagnosis, treatment, and research
By: edited by Krystyna E. Wisniewski, Nanbert Zhong.
Contributors: Wisniewski, K. E.; Zhong, Nanbert.
Series: Advances in genetics -- v.45
Publisher: Academic Press
Published: 2001
Place of publication: San Diego
Language: eng
Number of pages: 243
Subjects: Neuronal ceroid-lipofuscinosis; Molecular cloning
Description: This title will present all current knowledge of Batten disease from research to clinical evaluation. NCL is not well recognized in underdeveloped countries because the diagnostic technology is lacking. With the information in this volume, however, a specific diagnosis of NCL could be made. Also, specific familial mutations obtained through genetic tests may guide prenatal diagnoses for at-risk families.
Notes: Includes bibliographical references and index.
Table of contents: title: Neuronal ceroid lipofuscinoses: classification and diagnosis --; title: Cellular pathology and pathogenic aspects of neuronal ceroid lipofuscinoses --; title: Positional candidate gene cloning of CLN1 --; title: Biochemistry of neuronal ceroid lipofuscinoses --; title: Positional cloning of the JNCL gene, CLN3 --; title: Studies of homogenous populations: CLN5 and CLN8 --; title: Molecular genetic testing for neuronal ceroid lipofuscinoses --; title: Genetic counseling in the neuronal ceroid lipofuscinoses --; title: Neurotrophic factors as potential therapeutic agents in neuronal ceroid lipofuscinosis --; title: Animal models for the ceroid lipofuscinoses --; title: Experimental models of NCL: the yeast model --; title: Outlook for future treatment.