Cell death
By: editors-in-chief, Gerry Melino, David Vaux.
Contributors: Melino, Gerry.; Vaux, David.
Publisher: John Wiley & Sons
Published: 2010
Place of publication: Chichester, West Sussex; Hoboken, NJ
Language: eng
ISBN-13: 9780470715734
Subjects: Apoptosis; Apoptosis -- physiology; Apoptosis Regulatory Proteins -- metabolism
Description: "This book on cell death contains 29 self-contained, peer-reviewed articles written by leading scientists in each field. It features overview articles aimed at undergraduates and non-specialists, which present basic information and provide entry into the following advanced articles. These advanced articles are written for postgraduate students and research workers, containing detailed information and key references allowing the reader to investigate a specific area in more depth. The book is an essential resource for educational purposes as well as a reference work for experienced researchers in the field. The articles will also be available electronically as part of the acclaimed Encyclopedia of Life Sciences (ELS).Key features: Provides a comprehensive overview on the research of programmed cell death.Edited by leaders in the field.Clearly written and illustrated articles.Full colour throughout.A spin-on to the acclaimed reference work, the Encyclopedia of Life Science (ELS).Combines introductory information with coverage of the latest discoveries in the field.Features overview level articles for advanced students or people new to a topic and more advanced articles for those requiring more detailed information. Serves as a reference work for advanced students as well as researchers in this field.Ideal library purchase for science, medical, and technology libraries in academia, government, and industry; medical libraries; networks and consortia covering these markets"--Provided by publisher.
Notes: Includes bibliographical references and index.
Table of contents: title: (Publisher-supplied data)  The Siren's Song: This Death That Makes Life Live 1   Gerry Melino, Richard A Knight and Jean-Claude   Ameisen   The Origin and Evolution of Programmed Cell   Death 13   Jean Claude Ameisen   Cell Death in C. elegans 21   Ataman Sendoel and Michael O Hengartner   Caspases and Cell Death 30   Lorraine D Hernandez, Caroline Houde, Maarten   Hoek, Brent Butts, Donald W Nicholson and Huseyin   Mehmet   The Apoptosome: The Executioner of   Mitochondria-mediated Apoptosis 37   Elisabetta Ferraro and Francesco Cecconi   Caspases, Substrates and Sequential Activation 50   John G Walsh and Seamus J Martin   Dismantling the Apoptotic Cell 60   Paula Deming and Sally Kornbluth   The BCL-2 Family Proteins ? Key Regulators and   Effectors of Apoptosis 69   David L Vaux   BH3-only Proteins 75   Lina Happo, Andreas Strasser and Clare L Scott   Mitochondrial Outer Membrane Permeabilization 90   Melissa J Parsons and Douglas R Green   Mitochondria Fusion and Fission 97   Giovanni Benard, Guihong Peng and Mariusz   Karbowski   Death Receptors 110   Peter H Krammer and Inna N Lavrik   Death Receptors at the Molecular Level:   Therapeutic Implications 117   Marion MacFarlane   Death Receptor-induced Necroptosis 127   Wim Declercq, Franky Van Herreweghe,   Tom Vanden Berghe and Peter Vandenabeele   Inhibitor of Apoptosis (IAP) and BIR-containing   Proteins 138   David L Vaux   Structures, Domains and Functions in Cell Death   (DD, DED, CARD, PYD) 147   Hao Wu and Yu-Chih Lo   Structure and Function of IAP and Bcl-2 Proteins 156   Mark G Hinds, Peter D Mace and Catherine L Day   Engulfment of Apoptotic Cells and its Physiological   Roles; title: 165   Rikinari Hanayama, Masanori Miyanishi, Hiroshi   Yamaguchi, Jun Suzuki and Shigekazu Nagata   Autophagy 175   Mar??a Isabel Colombo and Hans-Uwe Simon   Autophagy in Nonmammalian Systems 189   Jahda H Hill and Eric H Baehrecke   Apoptosis: Regulatory Genes and Disease 197   James E Vince and John Silke   Caspases in Inflammation and Immunity 212   Philippe M LeBlanc and Maya Saleh   Immunity, Granzymes and Cell Killing 223   Nigel J Waterhouse, Olivia Susanto, KarinASedelies   and Joseph A Trapani   P53 and Cell Death 230   Kamil Wolyniec, Sue Haupt and Ygal Haupt   Cornification of the Skin: A Non-apoptotic Cell   Death Mechanism 240   E Candi, RA Knight and G Melino   v   Apoptosis: Inherited Disorders 253   Helen C Su and Michael J Lenardo   From Reactive Oxygen and Nitrogen Species to   Therapy 262   ScottRMcKercher, Tomohiro Nakamura and Stuart   A Lipton   Microbial Inhibitors of Apoptosis 272   Georg Ha?cker   Drug Discovery in Apoptosis 282   Tom O?Brien and Vishva M Dixit.