Peptide synthesis and applications
By: edited by Knud J. Jensen, Pernille Tofteng Shelton, Søren L. Pedersen
Edition: 2nd ed.
Series: Methods in molecular biology -- 1047; Springer protocols; Methods in molecular biology (Clifton, N.J.) -- 1047.; Springer protocols (Series)
Publisher: Humana Press; Humana
Published: 2013
Place of publication: New York
Language: eng
Number of pages: 253
ISBN-13: 9781627035439
Subjects: Peptides; Laboratory manuals; Synthesis; Peptide Biosynthesis; Laboratory Manuals
Description: Peptides are used ubiquitously for studies in biology, biochemistry, chemical biology, peptide based medicinal chemistry, and many other areas of research. There is a number of marketed peptide drugs, and the prospects for the development of new peptide drugs are very encouraging. The second edition of Peptide Synthesis and Applications expands upon the previous editions with current, detailed methodologies for peptide synthesis. With new chapters on laboratory protocols for both the specialist and the non-specialist. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Peptide Synthesis and Application, Second Edition seeks to aid scientists in understanding different approaches to the synthesis of peptides by using a broad range of methods and strategies.
Notes: Previous ed.: 2005.

Includes bibliographical references and index.
Table of contents: title: Solid-phase peptide synthesis : an introduction / Knud J. Jensen; title: Linkers, resins, and general procedures for solid-phase peptide synthesis / Pernille Tofteng Shelton and Knud J. Jensen; title: Peptide release, side-chain deprotection, work-up, and isolation / Søren L. Pedersen and Knud J. Jensen; title: Synthesis of peptides using tert-butyloxycarbonyl (Boc) as the [alpha]-amino protection group / Søren W. Pedersen, Christopher J. Armishaw, and Kristian Strømgaard; title: Sequential formation of regioselective disulfide bonds in synthetic peptides with multiple disulfide bonds / Fazel Shabanpoor, Mohammed Akhter Hossain, Feng Lin, and John D. Wade; title: Synthesis of cyclic disulfide-rich peptides / Muharrem Akcan and David J. Craik; title: Preparation of C-terminally modified chemokines by expressed protein ligation / Lars Baumann, Max Steinhagen, and Annette G. Beck-Sickinger; title: Synthesis of C-terminal peptide thioesters using Fmoc based solid-phase peptide chemistry / Pernille Tofteng Shelton and Knud J. Jensen; title: Backbone amide linker strategy : protocols for the synthesis of C-terminal peptide aldehydes / Pernille Tofteng Shelton and Knud J. Jensen; title: Synthesis of N-methylated peptides : on-resin methylation and microwave-assisted couplings / Renée Roodbeen and Knud J. Jensen; title: Synthesis of antimicrobial peptoids / Paul R. Hansen and Jens K. Munk; title: Synthesis of lipidated peptides / Federica Rosi and Gemma Triola; title: Solid-phase synthesis of phosphopeptides / Kim B. Højlys-Larsen and Knud J. Jensen; title: Synthesis of O-glycopeptides and construction of glycopeptide microarrays / Ola Blixt and Emiliano Cló; title: Instruments for automated peptide synthesis / Søren L. Pedersen and Knud J. Jensen; title: Microwave-asisted solid-phase peptide synthesis using the Biotage Syro Wave[TM] / Leila Malik and Knud J. Jensen; title: Microwave-assisted solid-phase peptide synthesis based on the Fmoc protecting group strategy (CEM) / Grace S. Vanier.