Objective and subjective visual functions in Stargardt macular dystrophy.
Published: 2007
Language: eng
Number of pages: 180
ISBN-13: 9780494274965
Description: Conclusions. The mfERG, kinetic ERG and VA LV VFQ testing along with current visual function measurement tools might provide clearer perspective of visual dysfunction in patients with STGD. This in turn might help to understand the natural history of STGD.Purpose. To assess visual function measures, selected from knowledge of disease mechanism, in their abilities to detect vision dysfunction, in patients with Stargardt Macular Dystrophy (STGD).Results. The mfERG was more sensitive in detecting dysfunction than bfERG (p&lt;0.0001). Subjects with STGD exhibited delayed rod dark adaptation (p&lt;0.0001). VA IN VFQ-48 was a valid, reliable measure of PVA. Those with STGD had a lower PVA, compared with controls (p&lt;0.001).Methods. 57 subjects with STGD and 67 age-matched control subjects were recruited. All the subjects recruited in the study underwent comprehensive visual function measurement tests including ISCEV standards full field electroretinogram (ERG) with the additional bright flash ERG (bfERG) rod response, multifocal ERG (mfERG), dark adaptation using a kinetic ERG, visual field assessment and questionnaire to assesses perceived visual ability (PVA) (VA LV VFQ-48 questionnaire), was considered a subjective visual function measure in this thesis.
Notes: Source: Masters Abstracts International, Volume: 45-06, page: 3141.

Thesis (M.Sc.)--University of Toronto, 2007.

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