Histone deacetylases
Subtitle: the biology and clinical implication
By: Tso-Pang Yao, Edward Seto, editors
Series: Handbook of experimental pharmacology -- v.206; Handbook of experimental pharmacology -- v.206.
Publisher: Springer
Published: 2011
Place of publication: Heidelberg
Language: eng
Number of pages: 260
ISBN-13: 9783642216305; 9783642216312
Subjects: Sirtuins; Drug therapy; Histone Deacetylase Inhibitors; Histone deacetylase; Neoplasms; Physiology; Histone Deacetylases
Notes: Includes bibliographical references and index.
Table of contents: title: K-acetylation and its enzymes: overview and new developments / Juliette Adjo Aka, Go-Woon Kim, Xiang-Jiao Yang.; title: Biology of HDAC in cancer: the nuclear and epigenetic components / Astrid Hagelkruys, Anna Sawicka, Magdalena Rennmayer, Christian Seiser.; title: Deacetylation of nonhistone proteins by HDACs and the implications in cancer / Lirong Peng, Edward Seto.; title: Biology and therapeutic implications of HDACs in the heart / Timothy A. McKinsey.; title: HDACs in skeletal muscle remodeling and neuromuscular disease / Bryan J. Simmons, Todd J. Cohen, Richard Bedlack, Tso-Pang Yao.; title: Rationale for HDAC inhibitor therapy in autoimmunity and trasplantation / Wayne W. Hancock.; title: Role of mammalian sirtuins in the regulation of metabolism, aging, and longevity / Akiko Satoh, Liana Stein, Shin Imai.; title: Mictochondrial sirtuins in the regulation of mictochondrial activity and metabolic adaption / David B. Lombard, Daniel X. Tishkoff, Jianjun Bao.; title: Characterization of nuclear sirtuins: molecular mechanisms and physiological relevance / Debra Toiber, Carlos Sebastian, Raul Mostoslavsky.; title: Structural biology of human netal-dependent histone deacetylases / Matthieu Schapira.; title: Sirtuin modulators / Sumit S. Mahajan, Vid Leko, Julian A. Simon, Antonio Bedalov.