ADP Ribosylation in Animal Tissues
Subtitle: Structure, Function, and Biology of Mono (ADP-Ribosyl) Transferases and Related Enzymes (Advances in Experimental Medicine and Biology)
Contributors: Friedrich Haag (Editor); Friedrich Koch-Nolte (Editor)
Edition: 1 edition
Publisher: Springer
Published: May 31, 1997
Language: eng
Format: Hardcover
Number of pages: 471
ISBN-13: 9780306455100
Subjects: Molecular biology; Zoology & animal sciences; Enzymology; Science; Health/Fitness; General; Life Sciences - Biochemistry; Life Sciences - Zoology - General; Science / Zoology; ADP-ribosylation; Adenosine Diphosphate Ribose; Congresses; NAD+ ADP-Ribosyltransferase; metabolism
Description: Documents the first conference on the topic, called in response to opportunities opened by the molecular characterization of the first mammalian mono (ADP-ribosyl) transferase enzyme from rabbit skeletal muscles, and the subsequent realization that one had already been to hand in a well-studied surface membrane protein of T cells, RT6. After introductions to the emerging gene families, the history of ADT- Ribose, and ADP-Ribosylation cycles, the 59 papers cover lessons from procaryotes, molecular approaches to studies in eucaryotes, the enzyme in the immune system and other animal tissues, the physiology of membrane proteins anchored by GPI, NAD+glycohydrolases and ADP- ribosylcyclases, and contemplation of the evolution of the enzyme in the context of the immune system. Appended is a proposal for a unified nomenclature for the relevant vertebrate gene family.