Renal Cell Carcinoma
Subtitle: Molecular Targets And Clinical Applications
Edition: 2 edition
Publisher: Humana Press
Published: July 4, 2008
Language: eng
Format: Hardcover
Number of pages: 500
ISBN-13: 9781588297372
Subjects: Renal medicine; Clinical Chemistry; Oncology; Medical
Description: In the second edition of their critically acclaimed book, Ronald Bukowski, Robert Motzer, and Robert Figlin have thoroughly updated and expanded their survey of clinical, biological and pathological management of localized and advanced renal cell carcinoma. A panel of internationally renowned contributors explores the latest developments in molecular genetics, focusing on the novel targets that have been discovered in epithelial renal tumors. The discussion includes the specific biology of selected target molecules or receptors and the various agents that inhibit these targets, including full chapters devoted to drugs that selectively inhibit receptor tyrosine kinases, such as sunitinib and axitinib. Further attention is paid to leading-edge strategies that target and inhibit tumor associated angiogenesis and block the vascular endothelial growth factor pathway. This book is the definitive text on the rapidly evolving landscape of experimental therapeutics, written and edited.