Biomechanics of Cells and Tissues
Subtitle: Experiments, Models and Simulations
By: edited by Paola Lecca
Contributors: SpringerLink (Online service)
Series: Lecture Notes in Computational Vision and Biomechanics -- 9
Publisher: Springer Netherlands; Imprint: Springer
Published: 2013
Place of publication: Dordrecht
Language: eng
Format: [electronic resource] :
Number of pages: 168
ISBN-13: 9789400758902
Subjects: Computational Biology/Bioinformatics; Global analysis (Mathematics); Biophysics and Biological Physics; Analysis; Engineering; Bioinformatics; Biotechnology; Biomedical engineering
Description: <p>The application of methodological approaches and mathematical formalisms proper to Physics and Engineering to investigate and describe biological processes and design biological structures has led to the development of many disciplines in the context of computational biology and biotechnology. The best known applicative domain is tissue engineering and its branches. Recent domains of interest are in the field of biophysics, e.g.: multiscale mechanics of biological membranes and films and filaments; multiscale mechanics of adhesion; biomolecular motors and force generation.</p><p> </p><p>Modern hypotheses, models, and tools are currently emerging and resulting from the convergence of the methods and phylosophycal apporaches of the different research areas and disciplines. All these emerging approaches share the purpose of disentangling the complexity of organisms, tissues, and cells and mimiking the function of living systems.</p><p><p>The contributions presented in this book are current research highlights of six challenging and representative applicative domains of phyisical, engineering, and computational approaches in medicine and biology, i.e tissue engineering, modelling of molecular structures, cell mechanics and cell adhesión processes, cancer physics, and physico-chemical processes of metabolic interactions. Each chapter presents a compendium or a review of the original results achieved by authors  in the last years. Furthermore, the book also wants to pinpoint the questions that are still open and that could propel the future research. </p><p><p>
Table of contents: title: <p>Preface; title: Computer-Aided Tissue Engineering: application to the case of Anterior Cruciate Ligament Repair, by C.P. Laurent; title: Process Modeling and Rendering of Biochemical Structures: Actin, by Ozan Kahramanogullari; title: A model predicting rolling cells percentage in inflamed brain venules, by Paola Lecca; title: Analysis and modeling of metabolism of cancer, by Miroslava Cuperlovic-Culf; title: Modelling the influence of cell signaling on the dynamics of gene regulatory networks, by Chiara Damiani; title: Mechanistic models of astrocytic glucose metabolism calibrated on PET images, by Paola Lecca; title: Author Biographies; title: Subject Index.</p>.