Toxicology of the gastrointestinal tract
By: edited by Shayne C. Gad
Series: Target organ toxicology series; Target organ toxicology series
Publisher: Taylor & Francis
Published: 2007
Place of publication: Boca Raton
Language: eng
Format: [electronic resource] /
Number of pages: 359
ISBN-13: 9781420004267
Subjects: Gastroenterology; Drug effects; MEDICAL; Gastrointestinal Tract; Pathophysiology; Intestinal Absorption; Gastrointestinal system; Toxicology; Physiology
Description: This book replaces Intestinal Toxicology, one of the original books in the Target Organ series. It provides a complete, multidimensional overview of the entire gastrointestinal system involved in the toxicity of exogenous agents. The book describes normal structures and functions, regulatory mechanisms of control, and the role of absorption and metabolism in the systemic toxicity of toxic agents. It includes detailed treatment of the mechanisms of action of substances on the GI tract and how such effects can adversely affect the functioning of other systems in the body. The book also covers ph.
Notes: "A CRC title."

Includes bibliographical references and index.

Description based on print version record.
Table of contents: title: Introduction: the gastrointestinal (GI) tract as a barrier and as an absorptive and metabolic organ / Shayne C. Gad; title: Methods for the analysis of gastrointestinal function / Robin C. Guy; title: Safety pharmacology and the GI tract / Henry I. Jacoby; title: Gastronintestinal tract development and its importance in toxicology / Joseph V. Rodricks, Allison A. Yates, Claire L. Kruger; title: The GI tract as the major route of pharmaceutical administration / Robert W. Kapp, Jr.; title: Gastrointestinal function and toxicology in canines / Charles Spainhour; title: Absorption of macromolecules by mammalian intestinal epithelium / Shayne C. Gad; title: Peyer's patch epithelium: an imperfect barrier / Gary R. Burleson and Florence G. Burleson; title: Alteration of intestinal function by xenobiotic exposure: animal models / Shayne C. Gad; title: Intestinal absorption and metabolism of xenobiotics in laboratory animals / William J. Brock; title: Normal and abnormal intestinal absorption by humans / David W. Hobson and Valerie L. Hobson; title: Intestinal absorption and metabolism of xenobiotics in humans / William J. Brock.