Muscle gene therapy
Subtitle: methods and protocols
By: edited by Dongsheng Duan
Series: Methods in molecular biology -- 709; Springer protocols; Methods in molecular biology (Clifton, N.J.) -- v. 709.; Springer protocols
Publisher: Humana
Published: 2011
Place of publication: New York, NY
Language: eng
Number of pages: 382
ISBN-13: 9781617379819; 9781617379826
Subjects: Duchenne Muscular Dystrophy; Laboratory Manuals; Muscles; Genetics; Diseases; Gene Therapy; Gene therapy; Therapy; Laboratory manuals; Methods
Notes: Includes bibliographical references and index.

Also available online.
Table of contents: title: Design and testing of regulatory cassettes for optimal activity in skeletal and cardiac muscles; title: Codon optimization of the microdystrophin gene for Duchene muscular dystrophy gene therapy; title: Monitoring Duchenne muscular dystrophy gene therapy with epitope-specific monoclonal antibodies; title: Methods for noninvasive monitoring of muscle fiber survival with an AAV vector encoding the mSEAP reporter gene; title: Monitoring murine skeletal muscle function for muscle gene therapy; title: Phenotyping cardiac gene therapy in mice; title: Golden retriever muscular dystrophy (GRMD): Developing and maintaining a colony and physiological functional measurements; title: Directed evolution of adeno-associated virus (AAV) as vector for muscle gene therapy; title: Systemic gene transfer to skeletal muscle using reengineered AAV vectors; title: Bioinformatic and functional optimization of antisense phosphorodiamidate morpholino oligomers (PMOs) for therapeutic modulation of RNA splicing in muscle; title: Engineering exon-skipping vectors expressing U7 snRNA constructs for Duchenne muscular dystrophy gene therapy; title: Application of microRNA in cardiac and skeletal muscle disease gene therapy; title: Molecular imaging of RNA interference therapy targeting PHD2 for treatment of myocardial ischemia; title: Lentiviral vector delivery of shRNA into cultured primary myogenic cells: A tool for therapeutic target validation; title: Fetal muscle gene therapy/gene delivery in large animals; title: Electroporation of plasmid DNA to swine muscle; title: Local gene delivery and methods to control immune responses in muscles of normal and dystrophic dogs; title: Gene transfer to muscle from the isolated regional circulation; title: AAV-mediated gene therapy to the isolated limb in rhesus macaques; title: Antisense oligo-mediated multiple exon skipping in a dog model of Duchenne muscular dystrophy; title: Whole body skeletal muscle transduction in neonatal dogs with AAV-9; title: A translatable, closed recirculation system for AAV6 vector-mediated myocardial gene delivery in the large animal; title: Method of gene delivery in large animal models of cardiovascular diseases; title: Percutaneous transendocardial delivery of self-complementary adeno-associated virus 6 in the canine.