Basic Pharmacology
Subtitle: Understanding Drug Actions and Reactions
By: editors, Rathinavelu, Ph. D., Appu
Contributors: Rathinavelu, Ph. D., Appu, author
Edition: First edition.
Series: Pharmacy Education Series
Publisher: Taylor and Francis
Published: 2017
Place of publication: London
Language: eng
Number of pages: 388
ISBN-13: 9781315272672
Subjects: Pharmacology; Pharmacologie
Description: "Intended for use in an introductory pharmacology course, Basic Pharmacology: Understanding Drug Actions and Reactions provides an in-depth discussion of how to apply the chemical and molecular pharmacology concepts, a discussion students need for more advanced study. The textbook introduces the principles of chemistry and biology necessary to understand drug interactions at the cellular level. The authors highlight chemical and physical properties of drugs, drug absorption and distribution, drug interactions with cellular receptors, and drug metabolism and elimination. The book begins with a review of chemical principles as they apply to drug molecules, focusing mainly on those for commonly prescribed drugs. The authors use drug structures to illustrate the chemical concepts learned in general and organic chemistry courses. They cover the dynamics of receptors in mediating the pharmacological effects of drugs. They clarify theories, drawn from the scientific literature, which explain drug-receptor interactions and the quantitative relationship between drug binding and its effects at the cellular level. The authors' extensive use of drug structures for teaching chemical and molecular pharmacology principles, and their emphasis on the relevance of these principles in future professional life makes this book unique. It provides the framework for better understanding of advanced pharmacology and therapeutics topics. Blending medicinal chemistry and pharmacodynamics aspects, this textbook clearly elucidates the essential concepts that form the cornerstone for further work in pharmacology."--Provided by publisher.
Table of contents: title: Part I Physicochemical Properties of Drugs; title: chapter 1 Fundamental Chemical Properties of Drugs; title: chapter 2 Acid-Base Properties of Drugs; title: chapter 3 Structural Determinants of Drug Action; title: chapter 4 Chemical Approacheas to the Treatment of Cancer; title: part II Principles of Biopharmaceutics; title: chapter 5 Administration and Absorption of Drugs; title: chapter 6 Distribution and Excretion of Drugs; title: chapter 7 Metabolic Changes of Drugs; title: part III Principles of Drug-Receptor and Drug-Enzyme Interactions; title: chapter 8 Drug Receptors and Pharmacodynamics; title: chapter 9 Drug-Induced Enzyme Inhibition; title: chapter 10 Drug-Receptor Dynamics and Theories; title: chapter 11 Receptor Regulation and Signaling Mechanisms.