Critical pathways to success in CNS drug development
By: Neal R. Cutler ... [et al.].
Contributors: Cutler, Neal R.
Publisher: Wiley-Blackwell; Wiley-Interscience
Published: 2010
Place of publication: Chichester, UK; Hoboken, NJ
Language: eng
Number of pages: 272
ISBN-13: 9781444330649
Subjects: Neuropsychopharmacology; Drug development; Critical path analysis; Central nervous system -- Effect of drugs on -- Research -- Methodology; Central Nervous System Agents -- pharmacology; Clinical Trials as Topic -- methods; Drug Evaluation -- methods; Drug Evaluation, Preclinical -- methods
Notes: Includes bibliographical references and index.
Table of contents: title: The impending crisis in CNS drug development; title: Animal models and procedures for CNS disorders; title: Pre-clinical antecedents to early human clinical trials; title: Biomarkers and surrogate markers in drug development; title: Neuroimaging and cognitive assessments in early drug development; title: Bridging and CSF studies; title: A case study from pre-clinical to early clinical trials.