Genomics in cancer drug discovery and development
By: edited by Garret M. Hampton, Karol Sikora.
Contributors: Hampton, Garret M.; Sikora, Karol.
Series: Advances in cancer research -- v. 96
Publisher: Elsevier/AP; Academic Press
Published: 2007
Place of publication: Amsterdam; Boston
Language: eng
Number of pages: 409
ISBN-13: 9780120066964
Subjects: Cancer -- Genetics; Genomics; Pharmacogenomics; Tumor markers; Cancer -- Molecular aspects
Notes: Includes bibliographical references and index.
Table of contents: title: Contributors to Volume 96; title: Introduction / Garret M. Hampton, Karol Sikora; title: Biomarker Discovery in Epithelial Ovarian Cancer by Genomic Approaches / Samuel C. Mok, Kevin M. Elias, Kwong-Kwok Wong, Kae Ho, Tomas Bonome, and Michael J. Birrer; title: Mass Spectrometry: Uncovering the Cancer Proteome for Diagnostics / Da-Elene van der Merwe, Katerina Oikonomopoulou, John Marshall, and Eleftherios P. Diamandis; title: Microarrays to Identify New Therapeutic Strategies for Cancer / Christopher Sears and Scott A. Armstrong; title: The Application of siRNA Technology to Cancer Biology Discovery / Uta Fuchs and Arndt Borkhardt; title: Ribozyme Technology for Cancer Gene Target Identification and Validation / Qi-Xiang Li, Philip Tan, Ning Ke, and Flossie Wong-Staal; title: Cancer Cell-Based Genomic and Small Molecule Screens / Jeremy S. Caldwell; title: Tumor Antigens as Surrogate Markers and Targets for Therapy and Vaccines / Angus Dalgleish and Hardev Pandha; title: Practices and Pitfalls of Mouse Cancer Models in Drug Discovery / Andrew L. Kung; title: Pharmacodynamic Biomarkers for Molecular Cancer Therapeutics / Debashis Sarker and Paul Workman; title: Biomarker Assay Translation from Discovery to Clinical Studies in Cancer Drug Development: Quantification of Emerging Protein Biomarkers / Jean W. Lee, Daniel Figeys, and Julian Vasilescu; title: Molecular Optical Imaging of Therapeutic Targets of Cancer / Kostantin Sokolov, Dawn Nida, Michael Descour, Alicia Lacy, Matthew Levy, Brad Hall, Su Dharmawardhane, Andrew Ellington, Brian Korgel, and Rebecca Richards-Kortum; title: Personalized Medicine for Cancer: From Molecular Signature to Therapeutic Choice / Karol Sikora; title: Cancer Drug Approval in the United States, Europe, and Japan / R.A.V. Milsted; title: Index.