Molecular diversity in drug design
By: edited by Philip M. Dean and Richard A. Lewis.
Contributors: Dean, P. M. 1944-; Lewis, Richard A.
Publisher: Kluwer Academic Publishers
Published: 1999
Place of publication: Dordrecht, the Netherlands; Boston
Language: eng
Number of pages: 253
Subjects: Drugs -- Design.; Pharmaceutical chemistry.; Molecular biology.; Drugs -- Structure-activity relationships.; Combinatorial chemistry.; Chemistry, Pharmaceutical.; Molecular Biology.; Structure-Activity Relationship.; Drugs -- Design.; Combinatorial chemistry.
Notes: Includes bibliographical references and index.
Table of contents: title: Issues in molecular diversity and the role of ligand binding sites / James Smith, Philip M. Dean and Richard A. Lewis; title: Molecular diversity in drug design : application to high-speed synthesis and high-throughput screening / Christopher G. Newton; title: Background theory of molecular diversity / Valerie J. Gillet; title: Absolute vs relative similarity and diversity / Jonathan S. Mason; title: Diversity in very large libraries / Lutz Weber and Michael Almstetter; title: Subset-selection methods for chemical databases / P. Willett; title: Molecular diversity in site-focused libraries / Diana C. Roe; title: Managing combinatorial chemistry information / Keith Davies and Catherine White; title: Design of small libraries for lead exploration / Per M. Andersson ... [et al.]; title: The design of small- and medium-sized focused combinatorial libraries / Richard A. Lewis.