The metabolic syndrome
Subtitle: epidemiology, clinical treatment, and underlying mechanisms
By: edited by Barbara Caleen Hansen, George A. Bray.
Contributors: Hansen, Barbara C.; Bray, George A.
Series: Contemporary endocrinology; Contemporary endocrinology (Totowa, N.J. : Unnumbered)
Publisher: Humana Press; Humana
Published: 2008
Place of publication: Totowa, N.J
Language: eng
Number of pages: 401
ISBN-13: 9781588297389
Subjects: Metabolic syndrome; Metabolic Syndrome X
Description: The writers stimulate new thinking concerning underlying mechanisms and encourage heightened efforts to develop new therapeutics, potentially targeting uniquely intersecting pathways. Developing this new synthesis and analysis of the Metabolic Syndrome will bring together the viewpoints of epidemiologists, physiologists, molecular biologists/biochemists, and clinicians toward understanding the current state of knowledge of both the causes and consequences of the Metabolic Syndrome.
Notes: Includes bibliographical references and index.
Table of contents: title: Metabolic syndrome: past and future: an introduction to the features of this book.; title: Metabolic syndrome: to be or not to be?; title: The role of obesity in insulin resistance: epidemiological and metabolic aspects.; title: Treatment of the metabolic syndrome with weight loss, exercise, hormones, and surgery.; title: Insulin resistance, metabolic syndrome, and cardiovascular disease: an epidemiological perspective.; title: The sympatho-adrenal system in the metabolic syndrome.; title: Insulin action and endothelial function.; title: Macro- and microvascular disease in an insulin-resistant pre-diabetic animal model: the JCR:LA-cp rat.; title: High-sensitivity C-reactive protein and the metabolic syndrome.; title: Insulin signaling in adipocytes and the role of inflammation.; title: Insulin resistance and dyslipidemia.; title: Pancreatic islet pathophysiology and pathology in obesity.; title: Glucagon-like peptides and insulin sensitivity.; title: The relationship between the insulin receptor substrates and metabolic disease.; title: Insulin resistance and inhibitors of the insulin receptor tyrosine kinase.; title: Fat feeding and muscle fat deposition eliciting insulin resistance: an update.; title: Alterations in atypical protein kinase C activation in insulin resistance syndromes.; title: The liver, glucose homeostasis, and insulin action in type 2 diabetes mellitus.; title: Chronomics of the metabolic syndrome.