Human chorionic gonadotropin
By: by Lawrence A. Cole
Contributors: ScienceDirect (Online service)
Series: Elsevier insights
Publisher: Elsevier
Published: 2010
Place of publication: Oxford
Language: eng
Format: [electronic resource] /
Number of pages: 400
ISBN-13: 9780123849076
Subjects: Chorionic gonadotropins
Description: Human chorionic gonadotropin (hCG) is produced during pregnancy by the embyro. It promotes progesterone production by corpus luteal cells. It also functions in pregnancy to promote angiogenesis in uterine vasculature, it immuno-blands the invading placental tissue so it is not rejected by the maternal uterine tissues, promotes the growth of the uterus in line with the growth of the fetus, promotes the differentiation of growing cytotrophoblast cells, promotes the quiescence of contractions in the uterine myometrium during the course of pregnancy, and also has function in growth and development of fetal organs. The book describes the detailed biology, clinical chemistry, and clinical perspectives of hCG and associated molecules and examines hCG, hyperglycosylated hCG and hCG free [beta]-subunit, 3 separate and independent molecules with totally sovereign physiological functions. It provides comprehensive information on hCG from basic science to clinical medicine Written by specialists in the field.
Notes: Electronic reproduction. Amsterdam : Elsevier Science & Technology, 2010. Mode of access: World Wide Web. System requirements: Web browser. Title from title screen (viewed on Sep. 27, 2010). Access may be restricted to users at subscribing institutions.
Table of contents: title: Genetics, synthesis, secretion, structure and degradation of hCG; title: Biological function of hCG; title: Clinical applications; title: hCG tests; title: Test applications; title: Basic methods; title: Evolution, summary and the future.