Epilepsy as a Dynamic Disease
By: edited by John Milton, Peter Jung
Contributors: Jung, Peter
Series: Biological and Medical Physics Series; Biological and Medical Physics Series
Publisher: Springer Berlin Heidelberg
Published: 2003
Place of publication: Berlin, Heidelberg
Language: eng
Format: [electronic resource] /
Number of pages: 418
ISBN-13: 9783642076657; 9783662050484
Subjects: Neurosciences; Neurology; Physics; Physiology; Mathematics
Description: A "brain defibrillator" may be closer than we think. An epileptic seizure involves a paroxysmal change in the activity of millions of neurons. Feedback control of seizures would require an implantable device that could predict seizure occurrence and then deliver a stimulus to abort it. To examine the feasibility of building such a device, this text brings together experts in epilepsy, bio-engineering, and dynamical systems theory. Topics include the development of epileptic systems, seizure prediction, neural synchronization, wave phenomena in excitable media, and the control of complex neural dynamics using brief electrical stimuli.
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Mode of access: World Wide Web.
Table of contents: title: 1. Medically Intractable Epilepsy; title: 2. Insights into Seizure Propagation from Axonal Conduction Times; title: 3. Dynamic Epileptic Systems versus Static Epileptic Foci?- 4. Neuroglia, the Other Brain Cells; title: 5. The Electroencephalogram (EEG); title: 6. Electrocorticographic Coherence Patterns of Epileptic Seizures; title: 7. Synchronization of Synaptically Coupled Neural Oscillators; title: 8. Controlling Neural Synchrony; title: 9. Modeling Pattern Formation in Excitable Media; title: 10. Are Cardiac Waves Relevant to Epileptic Wave Propagation?- 11. Pattern Formation in the Microbial World; title: 12. Predicting Epileptic Seizures; title: 13. Comparison of Methods for Seizure Detection; title: 14. Direct Deep Brain Stimulation; title: 15. Seizure Control Using Feedback and Electric Fields; title: 16. Aborting Seizures with a Single Stimulus; title: 17. Unstable Periodic Orbits (UPOs) and Chaos Control in Neural Systems; title: 18. Prospects for Building a Therapeutic Cortical Stimulator.