Handbook of Clinical Drug Data
Publisher: McGraw-Hill Medical Publishing
Published: January 2002
Language: eng
Number of pages: 1148
ISBN-13: 9780071124454
First sentence: Dihydroergotamine (DHE) is a semisynthetic ergot alkaloid that is hypothesized to exert its antimigraine effect via its agonist activity at the serotonin 5-HT receptor, resulting in vasoconstriction of intracranial blood vessels and inhibition of inflammatory neuropeptide release.