Inositol phospholipid signaling in physiology and disease
By: issue editors, William G. Kerr, and Sandra Fernandes
Contributors: Fernandes, Sandra (Sandra R.); Kerr, William G.; New York Academy of Sciences
Series: Annals of the New York Academy of Sciences -- v. 1280; Annals of the New York Academy of Sciences -- v. 1280.
Publisher: New York Academy of Sciences
Published: 2012
Place of publication: Hoboken, NJ
Language: eng
Number of pages: 54
ISBN-13: 9781573318914
Copyright date: 2013
Subjects: Inositol phosphates; Congresses; Phospholipids; Phosphatidylinositols; Signal Transduction; Phospholipides; Inositphosphatderivate; Phospholipide; Inositol
Description: "A recent upsurge of research examining inositol phospholipids (IP)--membrane-bound species fundamental to cell signalincontinues underscore the role of this pathway in both normal and disease-associated cellular physiology. This volume includes a selection of cutting-edge, multidisciplinary reports borne out of the conference "Inositol Phospholipid Signaling in Physiology and Disease" held June 26-27, 2012 at the New York Academy of Sciences in New York City. Papers include important developments investigating IP signaling in immunology, cancer, inflammation, and metabolic disorders"--Publisher's description.
Notes: Includes bibliographical references.
Table of contents: title: Introduction to Inositol phospholipid signaling in physiology and disease / William G. Kerr and Sandra Fernandes; title: Phosphoinositide 3-kinase and INPP4B in human breast cancer / Micka C. Bertucci and Christina A. Mitchell; title: Role of SHIP1 in cancer and mucosal inflammation / Sandra Fernandes, Sonia Iyer and William G. Kerr; title: Role of SHIP1 in bone biology / Sonia Iyer, Bryan S. Margulies and William G. Kerr; title: Achieving cancer cell death with PI3K/mTOR-targeted therapies / Sung Su Yea and David A. Fruman; title: Challenges in the clinical development of PI3K inhibitors / Cristian Massacesi, Emmanuelle di Tomaso, Nathalie Fretault and Samit Hirawat; title: Rules of engagement : distinct functions for the four class I PI3K catalytic isoforms in immunity / Klaus Okkenhaug; title: Control of T cell tolerance by phosphatase and tensin homolog / Alexandria Huynh and Laurence A. Turka; title: Role of PI3K/Akt and mTOR complexes in Th17 cell differentiation / Shigenori Nagai, Yutaka Kurebayashi and Shigeo Koyasu; title: Targeting phosphoinositide 3-kinase [delta] for the treatment of respiratory diseases / Srividya Sriskantharajah, Nicole Hamblin, Sally Worsley, Andrew R. Calver, Edith M. Hessel and Augustin Amour; title: Phosphoinositide 3-kinase gamma in T cell biology and disease therapy / Wai-Ping Fung-Leung; title: Inhibition of phosphoinositide 3-kinase [gamma] attenuates inflammation, obesity, and cardiovascular risk factors / Matthias P. Wymann and Giovanni Solinas; title: Class III PI3K Vps34: essential roles in autophagy, endocytosis, and heart and liver function / Nadia Jaber and Wei-Xing Zong; title: Inpp4b is a novel negative modulator of osteoclast differentiation and a prognostic locus for human osteoporosis / Jean Vacher.