PARP as a Therapeutic Target (Handbooks in Pharmacology and Toxicology)
Publisher: CRC
Published: March 6, 2002
Language: eng
Format: Hardcover
Number of pages: 360
ISBN-13: 9780849300738
Subjects: NAD-ADP-ribosyltransferase; Cytology; Drug Delivery Systems; Medical; Medical / Nursing; Toxicology; Therapeutic use; Pharmacology; Medical / Pharmacology; Inhibitors; Life Sciences - Cytology; Testing
First sentence: Poly(ADP-ribose) polymerase-1 (PARP-1) was first identified as a nuclear enzyme involved in DNA repair, and as such was of principal interest to studies of the cell cycle and alterations that can lead to cancer.