G Protein Pathways, Part A
Subtitle: Receptors (Methods in Enzymology, Volume 343) (Methods in Enzymology)
Contributors: Ravi Iyengar (Editor); John D. Hildebrandt (Editor)
Edition: 1st edition
Publisher: Academic Press
Published: October 2001
Language: eng
Format: Hardcover
Number of pages: 680
ISBN-13: 9780121822446
Subjects: Enzymology; Science; Proteins; Science/Mathematics; Biochemistry; Life Sciences - Biochemistry; Life Sciences - Biology - Molecular Biology; Biomedical Sciences; Cell Biology; Molecular Biology; Neuroscience; Pharmacology; Science / Biochemistry
First sentence: Over the past decade it has become accepted that G protein-coupled receptors (GPCRs) can activate G proteins and thus initiate signaling in the absence of agonist; this spontaneous receptor activity can be inhibited to varying degrees by antagonists, a phenomenon termed inverse agonism.