Chemical proteomics
Subtitle: methods and protocols
By: edited by Gerard Drews and Marcus Bantscheff
Series: Methods in Molecular Biology -- 803; Springer protocols; Methods in molecular biology (Clifton, N.J.) -- v. 803.; Springer protocols
Publisher: Humana Press
Published: 2012
Place of publication: New York
Language: eng
Number of pages: 313
ISBN-13: 9781617793639
Subjects: Analytical Chemistry Techniques; Methods; Biochemistry; Proteomics; Laboratory manuals; Laboratory Manuals
Notes: Includes bibliographical references and index.
Table of contents: title: Mass spectrometry-based chemoproteomic approaches / Marcus Bantscheff; title: Chemical proteomics in drug discovery / Gerard Drewes; title: Compound immobilization and drug-affinity chromatography / Uwe Rix, Manuela Gridling, and Giulio Superti-Furga; title: Affinity-based chemoproteomics with small molecule-peptide conjugates / Chaitanya Saxena; title: A chemical proteomic probe for detecting dehydrogenases : catechol rhodanine / Xia Ge and Daniel S. Sem; title: Probing proteomes with benzophenone photoprobes / Akira Kawamura and Doina M. Mihai; title: Biotinylated probes for the analysis of protein modification by electrophiles / Simona G. Codreanu ... [et al.]; title: Profiling of methyltransferases and other S-adenosyl-L-homocysteine-binding proteins by capture compound mass spectrometry / Thomas Lenz ... [et al.]; title: Identifying cellular targets of small-molecule probes and drugs with biochemical enrichment and SILAC / Shao-En Ong ... [et al.]; title: Determination of kinase inhibitor potencies in cell extracts by competition binding assays and isobaric mass tags / Carsten Hopf ... [et al.]; title: Affinity-based profiling of dehydrogenase subproteomes / Xia Ge and DAniel S. Sem; title: Probing the specificity of protein-protein interactions by quantitative chemical proteomics / Duangnapa Kovanich ... [et al.]; title: Fluorescence-based proteasome activity profiling / Annamieke de Jong ... [et al.]; title: Chemical cross-linking and high-resolution mass spectrometry to study protein-drug interactions / Mathias Q. Müller and Andrea Sinz; title: Monitoring ligand modulation of protein-protein interactions by chemical cross-linking and high-mass MALDI mass spectrometry / Natalia Gasilova and Alexis Nazabal; title: Time-controlled transcardiac perfusion crosslinking for in vivo interactome studies / Amy Hye Won Jeon and Gerold Schmitt-Ulms; title: Ligand discovery using small-molecule microarrays / Dominick E. Casalena, Dina Wassaf, and Angela N. Koehler; title: Working with small molecules : preparing and storing stock solutions and determination of kinetic solubility / Andrea Wolf, Satoko Shimamura, and Friedrich B.M. Reinhard; title: A database for chemical proteomics : ChEBI / Paula de Matos ... [et al.]; title: Working with small molecules : rules-of-thumb of drug likeness / Ming-Qiang Zhang.