Proteases and cancer
Subtitle: methods and protocols
By: edited by Toni M. Antalis and Thomas H. Bugge
Series: Methods in molecular biology -- 539; Springer protocols
Publisher: Humana, Springer
Published: 2009
Place of publication: New York, N.Y
Language: eng
Number of pages: 221
ISBN-13: 9781603270021; 9781603270038
Subjects: Cancer; Molecular aspects; Proteolytic enzymes; Neoplasms; Analysis; Enzymology; Laboratory Manuals; Peptide Hydrolases
Notes: Includes bibliographical references and index.
Table of contents: title: 1. Delineating protease functions during cancer development / Nesrine I. Affara, Pauline Andreu, and Lisa M. Coussens; title: 2. Proteolytic systems: constructing degradomes / Gonzalo R. Ordóñez ... [et al.]; title: 3. Microarrays for protease detection in tissues and cells / Kamiar Moin ... [et al.]; title: 4. Positional scanning synthetic combinatorial libraries for substrate profiling / Eric L. Schneider and Charles S. Craik; title: 5. Mixture-based peptide libraries for identifying protease cleavage motifs / Benjamin E. Turk; title: 6. High throughput substrate phage display for protease profiling / Boris Ratnikov, Piotr Cieplak, and Jeffrey W. Smith; title: 7. Imaging specific cell surface protease activity in living cells using reengineered bacterial cytotoxins / John P. Hobson ... [et al.]; title: 8. Cell-based identification of natural substrates and cleavage-sites for extracellular proteases by SILAC proteomics / Magda Gioia, Leonard J. Foster, and Christopher M. Overall; title: 9. Optical proteolytic beacons for in vivo detection of matrix metalloproteinase activity; title: J. Oliver McIntyre and Lynn M. Matrisian; title: 10. Dissecting the urokinase activation pathway using urokinase-activated anthrax toxin / Shihui Liu ... [et al.]; title: 11. On-demand cleavable linkers for radioimmunotherapy / Pappanaicken R. Kumaresan, Juntao Luo, and Kit S. Lam.