impact of therapeutic modality on outcomes following repair of ruptured intracranial aneurysms: An administrative data analysis.
Published: 2006
Language: eng
Number of pages: 105
ISBN-13: 9780494211939
Description: Using provincial administrative data from Ontario, we conducted a retrospective cohort study of adult subarachnoid hemorrhage (SAH) patients undergoing aneurysm repair, comparing open surgical clipping and endovascular coiling of the ruptured aneurysm. Between January 1, 1995 and September 30, 2004, 2342 aneurysms were clipped and 778 were coiled in Ontario. The proportion of aneurysms treated by coiling increased steadily over time. In analysis of the primary outcome, endovascular coiling was associated with a significantly increased hazard of death or SAH readmission (HR 1.25, p&lt;0.05). Similar results were obtained from the propensity score matched analysis (HR 1.23, p&lt;0.05). Endovascular coiling was associated with a significantly higher rate of diagnostic and repeat therapeutic procedures. Given the limitations inherent to this form of analysis, further clinical studies, rigorously assessing the performance of endovascular therapy in aneurysm patients, are indicated.
Notes: Source: Masters Abstracts International, Volume: 45-03, page: 1445.

Thesis (M.Sc.)--University of Toronto, 2006.

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