Tumor-induced immune suppression
Subtitle: mechanisms and therapeutic reversal
By: Dmitry I. Gabrilovich, Arthur A. Hurwitz, editors.
Contributors: Gabrilovich, Dmitry I.; Hurwitz, Arthur A.
Publisher: Springer
Published: 2008
Place of publication: New York, NY
Language: eng
Number of pages: 301
ISBN-13: 9780387691176; 9780387691183
Subjects: Tumors -- Immunological aspects; Immunosuppression; Neoplasms -- immunology; T-Lymphocytes -- immunology; Immunotherapy -- methods; Neoplasms -- therapy; T-Lymphocytes, Regulatory
Description: This book presents a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It will discuss a number of new mechanisms that have never been discussed in a monograph before: T-cell inhibitory molecules, regulatory tolerogenic DCs, and signaling pathways in antigen-presenting cells involved in T-cell tolerance.
Notes: Includes bibliographical references and index.