Applied statistics for network biology
Subtitle: methods in systems biology
By: edited by Matthias Dehmer ... [et al.].
Series: Quantitative and network biology -- v.1; Quantitative and network biology -- v.1.
Publisher: Wiley-Blackwell
Published: 2011
Place of publication: Weinheim, Germany
Language: eng
Number of pages: 454
ISBN-13: 9783527327508
Subjects: Systems biology; Statistical methods; Computational Biology; Statistics as Topic
Notes: Includes bibliographical references and index.
Table of contents: title: Pt. One. Modeling, simulation, and meaning of gene networks: 1. Network analysis to interpret complex phenotypes; title: 2. Stochastic modeling of gene regulatory networks; title: 3. Modeling expression quantitative trait loci in multiple populations; title: Pt. Two. Inference of gene networks: 4. Transcriptional network inference based on information theory; title: 5. Elucidation of general and condition-dependent gene pathways using mixture models and bayesian networks; title: 6. Multiscale network reconstruction from gene expression measurements: correlations, perturbations, and "A Priori Biological Knowledge"; title: 7. Gene regulatory networks inference: combining a genetic programming and H [infinity symbol] filtering approach; title: 8. Computational reconstruction of protein interaction networks; title: Pt. Three. Analysis of gene networks: 9. What if the fit is unfit? Criteria for biological systems estimation beyond residual errors; title: 10. Machine learning methods for identifying essential genes and proteins in networks; title: 11. Gene coexpression networks for the analysis of DNA microarray data; title: 12. Correlation network analysis and knowledge integration; title: 13. Network screening: a new method to identify active networks from an ensemble of known networks; title: 14. Community detection in biological networks; title: 15. On some inverse problems in generating probabilistic boolean networks; title: 16. Boolean analysis of gene expression datasets; title: Pt. Four. Systems approach to diseases: 17. Representing cancer cell trajectories in a phase-space diagram: switching cellular states by biological phase transitions; title: 18. Protein network analysis for disease gene identification and prioritization; title: 19. Pathways and networks as functional descriptors for human disease and drug response endpoints.