THE EFFECTS OF POSITIVE INSPIRATORY PRESSURE AND NEGATIVE PRESSURE DURING ENDOTRACHEAL SUCTIONING ON OXYGENATION, SECRETION RECOVERY, AND TRACHEOBRONCHIAL TRAUMA IN INTUBATED AND VENTILATED PREMATURE INFANTS AND KITTENS.
Contributors: University of California, San Francisco.
Published: 1984
Number of pages: 253
Subjects: Health Sciences, Nursing.
Description: Using two research protocols, two modifications of an endotracheal suctioning procedure were examined for the effects on oxygenation, secretion recovery, and tracheobronchial trauma. The two modifications were; the type of negative pressure applied during endotracheal suctioning and the use of positive inspiratory pressure during endotracheal suctioning.

In the first protocol, nineteen intubated and ventilated premature infants received two endotracheal suctioning procedures, once using continuous negative pressure and once using intermittent negative pressure, to determine the effects on transcutaneous oxygen tension (tcPO(,2)), secretion recovery, and tracheobronchial trauma. Tracheobronchial trauma was measued indirectly through the use of serial blood cultures taken prior to suctioning, 2 minutes after suctioning, and 5 minutes after suctioning to determine the incidence of bacteremia.

There were no significant differences (P > .05) between the effects of the two types of negative pressure used during endotracheal suctioning on the weight of secretions recovered during suctioning or in the changes in the areas under the tcPO(,2) curve during and following endotracheal suctioning. Both types of negative pressure caused tcPO(,2) levels to decrease during and immediately following endotracheal suctioning. Since no organisms were recovered from serial blood cultures, no determination could be made concerning tracheobronchial trauma associated with each of the endotracheal suctioning procedures.

In the second protocol, five groups of 3 to 4 month old kittens (N = 34) underwent anesthesia, intubation, and ventilation to determine the effects of suction catheter insertion and endotracheal suctioning with and without positive inspiratory pressure on tcPO(,2) levels, secretion recovery, and tracheobronchial trauma. Over a three hour period 2 groups of kittens received 9 sham endotracheal suctioning procedures, 2 groups of kittens received 9 endotracheal suctioning procedures and the remaining group of kittens served as a surgical control group.

Positive inspiratory pressure with endotracheal suctioning did not significantly (P > .05) affect the amount or weight of secretions removed during the procedure. Suction catheter insertion and negative pressure both with and without supplemental inspiratory pressure caused tcPO(,2) levels to decrease both during and following suctioning. There were statistically significant (P < .005) differences between the groups in the tcPO(,2) levels during and following endotracheal suctioning. The decrease was least in the suction catheter insertion groups. . . . (Author's abstract exceeds stipulated maximum length. Discontinued here with permission of author.) UMI.
Notes: Source: Dissertation Abstracts International, Volume: 46-02, Section: B, page: 0477.

Thesis (D.N.S.)--UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, 1984.

School code: 0034.