Selective Estrogen Receptor Modulators
Subtitle: A New Brand of Multitarget Drugs
Contributors: Antonio Cano (Editor); Joacquim Calaf i Alsina (Editor); Jose Luis Duenas-Diez (Editor)
Edition: 1 edition
Publisher: Springer
Published: July 26, 2006
Language: eng
Format: Hardcover
Number of pages: 358
ISBN-13: 9783540242277
Subjects: Pharmacology; Rheumatology; Gynecology & Obstetrics; Medical; Medical / Nursing; Endocrinology & Metabolism; Estrogen Receptors; Mechanisms of Action; Medical / Gynecology & Obstetrics; Osteoporosis prevetion; Osteorporosis treatment; SERMS; Antagonists; Estrogen; Hormone therapy; Menopause; Selective estrogen receptor modulators
Description: The concept of selective estrogen receptor modulators (SERMs) has emerged recently in modern medicine. Two main features, the evidence of the wide expression of estrogen receptors in organs and systems and the growing information on the determinants of estrogen action, have allowed the envisioning of compounds with "a la carte" estrogenic profiles. The availability of substances performing as agonists wherever the estrogenic action is beneficial and as antagonists where it is not, is becoming less of a dream than of a closer reality. This book is an up-to-date review of the principal basic mechanisms and the clinical data integrating the actual current knowledge on SERMs.