Handbook of adaptive designs in pharmaceutical and clinical development
By: edited by Annpey Pong, Shein-Chung Chow
Publisher: CRC Press
Published: 2011
Place of publication: Boca Raton
Language: eng
ISBN-13: 9781439810163
Description: "This comprehensive guide offers a unified presentation of the principles and methodologies in adaptive design and analysis. It gives a well-balanced summary of current regulatory perspectives and recently developed statistical methods in this area. The handbook provides some insight regarding early phase and later phase adaptive designs. With a focus on the implementation of adaptive methods in clinical trials, it introduces the concepts of role, responsibility, function, and activity of a data safety monitoring board (DSMB) when applying these methods. Other important topics covered in detail include regulatory perspectives and logistics issues in applying adaptive design methods"--Provided by publisher.
Notes: Includes bibliographical references and index.