Death receptors and cognate ligands in cancer
By: Holger Kalthoff (ed.).
Contributors: SpringerLink (Online service)
Series: Results and problems in cell differentiation -- 49
Publisher: Springer
Published: 2009
Place of publication: Heidelberg; New York
Language: eng
Number of pages: 280
ISBN-13: 9783642030444; 9783642030451
Subjects: Etiology; Death Domain Receptors; Tumor Necrosis Factor Receptors; Cancer; Molecular aspects; Carcinogenesis; Neoplasms; Receptors; Physiological effect; Therapy; Treatment; Tumor necrosis factor; Physiology; Cell receptors
Notes: Includes bibliographical references and index.
Table of contents: title: The role of TNF in cancer / Harald Wajant; title: Many checkpoints on the road to cell death: regulation of Fas-FasL interactions and Fas signaling in peripheral immune responses / Madhu Ramaswamy ... [et al.]; title: FasL expression and reverse signaling / M. Lettau ... [et al.]; title: Impact of TNF-R1 and CD95 internalization on apoptotic and antiapoptotic signaling / Stefan Schütze and Wulf Schneider-Brachert; title: Ubiquitination and TNFR1 signaling / Ken-ichi Fujita and Srinivasa M. Srinivasula; title: From biochemical principles of apoptosis induction by TRAIL to application in tumour therapy / Stefanie M. Cordier, Kerstin Papenfuss, and Henning Walczak; title: Therapeutic targeting of TWEAK/Fn14 in cancer: exploiting the intrinsic tumor cell killing capacity of the pathway / Jennifer S. Michaelson and Linda C. Burkly; title: APRIL in B-cell malignancies and autoimmunity / Fiona C. Kimberly, Jan Paul Medema, and Michael Hahne; title: Autophagy in cancer and chemotherapy / Shida Yousefi and Hans-Uwe Simon; title: Glucocorticoid-mediated apoptosis resistance of solid tumors / Ingrid Herr, Markus W. Büchler, and Jürgen Mattern; title: Targeting death-receptors in radiation therapy / Olivier Niemöller and Claus Belka; title: Death ligands designed to kill: development and application of targeted cancer therapeutics based on proapoptotic TNF family ligands / Jeannette Gerspach, Harald Wajant, and Klaus Pfizenmaier.