Medicinal chemistry
Subtitle: chemistry and molecular aspects of drug design and action
By: editors, P.N. Kourounakis and E.A. Rekka.
Contributors: Kourounakis, P. N.; Rekka, E. A.
Publisher: Taylor & Francis
Published: 2007
Place of publication: Boca Raton
Language: eng
Number of pages: 356
ISBN-13: 9780849390067
Subjects: Pharmaceutical chemistry; Drugs -- Design; Chemistry, Pharmaceutical; Drug Design; Pharmacologic Actions
Notes: "A CRC title."

Includes bibliographical references and index.
Table of contents: title: Inflammatory mechanisms in Alzheimer's disease and other neurodegenerative disorders / J. Rogers ... [et al.]; title: Treatment development strategies for Alzheimer's disease / E. Wülfert; title: Lipoprotein-associated phospholipase A2 as a new prognostic factor for coronary artery disease / A. Tselepis; title: Protein modifications by nitric oxide and reactive nitrogen species / H. Ischiropoulos; title: Design, synthesis, and pharmacological evaluation of high affinity and selectivity sigma-1 and sigma-2 receptor ligands / J.H. Poupaert; title: Synthesis of biologically active taxoids / K.C. Nicolaou and R.K. Guy; title: From the molecular pharmacology to the medicinal chemistry of cannabinoids / D.M. Lambert; title: New inhibitors of DNA topoisomerase in the treatment of experimental malignancies / C. Atassi; title: Treatment of psoriasis with anthrones-biochemical aspects / W. Wiegrebe and K. Müller; title: An appraisal of fomocaines, current situation, and outlook / H. Oelschläger and A. Seeling; title: Ligands for the GABA recognition site at the GABAA receptor: structure-activity studies / B. Frølund ... [et al.]; title: Discovery of potent and selective inhibitors of human aldosterone synthase (CYP11B2): a new target for the treatment of congestive heart failure and myocardial fibrosis: a review / R.W. Hartmann ... [et al.]; title: Thiocarboxanilides: a new class of non-nucleoside reverse transcriptase inhibitors (NNRTIS) with great potential for the treatment of human immunodeficiency virus type 1 (HIV-1) infections / E. De Clercq, A. Karlsson, and J. Balzarini; title: Histamine H3-receptor agonists and antagonists: chemical, pharmacological, and clinical aspects / H. Stark and W. Schunack; title: Anti-inflammatory actions of flavonoids and structural requirements / T. Theoharides; title: Molecular mechanisms of H2O2-induced DNA damage: the action of desferrioxamine / M. Tenopoulou, P.-T Doulias, and D. Galaris; title: LNA (locked nucleic acid) and functionalized LNA: towards efficient gene targeting / J. Wengel; title: The effect of diet on drug metabolism / K.J. Netter; title: Cytochromes P450 in the metabolism and bioactivation of chemicals / C. Ioannides; title: In vitro methods to measure drug metabolism and metabolic interactions in drug discovery and development / O. Pelkonen ... [et al.]; title: How to probe the sites of action of drug molecules / A. Makriyannis and F. Bitter; title: Lipophilicity as a descriptor of molecular properties in drug design / B. Testa ... [et al.]; title: Drug membrane interaction and the importance for drug transport, distribution, accumulation, efficacy, and resistance / J.K. Seydel ... [et al.]; title: Structure-based and computer-aided drug design / H. Kubinyi; title: Physicochemical profiling in early drug discovery: new challenges at the age of high-throughput screen and combinatorial chemistry / B. Faller.