Telomeres
By: edited by Titia de Lange, Vicki Lundblad,  Elizabeth Blackburn.
Contributors: De Lange, Titia.; Lundblad, Vicki.; Blackburn, Elizabeth H.
Edition: 2nd ed.
Series: Cold Spring Harbor monograph series ;; monograph 45; Cold Spring Harbor monograph series ;; 45.
Publisher: Cold Spring Harbor Laboratory Press
Published: 2006
Place of publication: Cold Spring Harbor, N.Y
Language: eng
Number of pages: 576
Subjects: Telomere; Telomere -- physiology; Aging -- genetics; Neoplasms -- genetics
Description: Chapters in this volume cover telomere structure and function in a range of organisms, focusing on how they are maintained, their roles in cell division and gene expression, and how deficiencies in these structures contribute to cancers and other diseases and even aging.
Notes: Includes index.
Table of contents: title: A history of telomere biology; title: The telomerase RNP; title: Telomerase biochemistry and biogenesis; title: Telomerase and human cancer; title: Modeling cancer and aging in the telomerase deficient mouse; title: Telomerase deficiency and human disease; title: Telomerase independent maintenance of mammalian telomeres; title: Telomerase-independent telomere maintenance in yeast; title: Meiotic telomeres; title: Telomere position effect : silencing near the end; title: The structural biology of telomeres; title: Budding yeast; title: Mammalian telomeres; title: Drosophila telomeres; title: Ciliate telomeres; title: Fission yeast telomeres; title: Plant telomeres.