Genomic tools reveal changing Plasmodium falciparum populations
Contributors: Wirth, Dyann F.; Marti, Matthias; Berger, Bonnie; Udhayakumar, Venkatachalam; Clardy, Jon
Published: 2013
Language: eng
Description: A new era of malaria eradication programs relies on increased knowledge of the parasite through sequencing of the Plasmodium genome. Programs call for re-orientation at specific epidemiological markers as regions move from control towards pre- and total elimination. However, relatively little is known about the effects of intervention strategies on the parasite population or if the epidemiological cues correspond to effects on the parasite population.
Notes: Keywords: cerebral malaria, drug resistance, high resolution melting, molecular barcode, plasmodium falciparum, population genetics.

Thesis Ph.D. Harvard University 2013