Design and analysis of quality of life studies in clinical trials
By: Diane L. Fairclough.
Edition: 2nd ed.
Series: Chapman & Hall/CRC interdisciplinary statistics series; Interdisciplinary statistics
Publisher: Chapman & Hall/CRC
Published: 2010
Place of publication: Boca Raton
Language: eng
ISBN-13: 9781420061178
Subjects: Clinical trials -- Longitudinal studies; Clinical trials -- Statistical methods; Quality of life -- Research -- Methodology; Quality of Life; Statistics as Topic; Clinical Trials as Topic; Longitudinal Studies; Research -- methods
Notes: Includes bibliographical references and index.
Table of contents: title: Introduction and examples; title: Study design and protocol development; title: Models for longitudinal studies I; title: Models for longitudinal studies II; title: Moderation and mediation; title: Characterization of missing data; title: Analysis of studies with missing data; title: Simple imputation; title: Multiple imputation; title: Random effects dependent dropout; title: Selection models; title: Multiple endpoints; title: Composite endpoints and summary measures; title: Quality adjusted life-years (QALYs) and Q-TWIST; title: Analysis plans and reporting results.