The cell cycle and differentiation in stem cells
Contributors: Kirschner, Marc W.; Lahav, Galit; Fontana, Walter; Manalis, Scott R.
Published: 2012
Language: eng
Description: The relationship between cellular proliferation and differentiation is a major topic in cell biology. What we know comes from models of somatic cell differentiation, where it is widely viewed that cycling and differentiation are coupled, antagonistic phenomena linked at the G1 phase.
Notes: Keywords: Cell cycle, Decoupling, Gap 1 phase, Self-renewal, Stem cell, Stemness.

Thesis Ph.D. Harvard University 2012