Novel anticancer agents
Subtitle: stategies for discovery and clinical testing
By: editors, Alex A. Adjei, John K. Buolamwini.
Contributors: Adjei, Alex A.; Buolamwini, John K.
Publisher: Elsevier Academic Press
Published: 2006
Place of publication: Amsterdam; Boston
Language: eng
Number of pages: 437
Subjects: Antineoplastic agents -- Design; Antineoplastic agents -- Development; Antineoplastic Agents -- pharmacokinetics; Drug Delivery Systems; Drug Design; Clinical Trials as Topic
Notes: Includes bibliographical references and index.
Table of contents: title: A survey of novel molecular targets for anticancer drug discovery.; title: Microarrays: small spots produce major advances in pharmacogenenomics.; title: Strategies to target chemotherapeutics to tumors.; title: QSAR and pharmacophore mapping strategies in novel anticancer drug discovery.; title: Applications of nuclear magnetic resonance and mass spectrometry to anticancer drug discovery.; title: Antisense strategies for the development of novel cancer therapeutics.; title: Antibodies and vaccines as novel cancer therapeutics.; title: Inhibitors of apoptosis as targets for cancer therapy.; title: Preclinical testing and validation of novel anticancer agents.; title: Surrogate end points and biomarkers for early trials of novel anticancer agents.; title: Regulatory considerations in clinical trials of novel anticancer drugs.; title: Improving the efficacy and safety of anticancer agents: the role of pharmacogenetics.; title: Imaging of pharmacodynamic end points in clinical trials.; title: Devising proof-of-concept strategies in oncology clinical trials.; title: Clinical trial designs for cytostatic agents and agents directed at novel molecular targets.; title: Cancer gene therapy clinical trials: from the bench to the clinic.; title: Molecular targets for radiosensitization.; title: Patient accrual to clinical trials.