Modeling pulsed magnetization transfer:  An evaluation of principles and techniques.
Published: 2006
Language: eng
Number of pages: 70
ISBN-13: 9780494212707
Description: Modeling the effects of clinical MT scans, which generate contrast using short, shaped radiofrequency pulses (Pulsed MT), is complex and time consuming. As a result, the models which are currently used for Pulsed MT data analysis involve a variety of simplifying approximations.The objective of this work was to investigate the effects of such approximations on the accuracy of MT results. To address this objective, a Pulsed MT model was developed with minimal approximations. This model and three other, more approximate, techniques were then compared. The results of this comparison established the accuracy of these techniques, which continue to contribute to the current body of qMT research.Magnetization transfer (MT) is a magnetic resonance imaging (MRI) technique that generates contrast based on the exchange of magnetization between macromolecular and water protons. MT techniques have demonstrated sensitivity to the changes in tissue structure that occur in a variety of neurological disorders.
Notes: Source: Masters Abstracts International, Volume: 45-03, page: 1414.

Thesis (M.Sc.)--University of Toronto, 2006.

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