Genetic effects on environmental vulnerability to disease
By: edited by Michael Rutter
Contributors: Novartis Foundation
Series: Novartis Foundation symposium -- 293
Publisher: Wiley-Blackwell (an imprint of John Wiley & Sons Ltd)
Published: 2008
Place of publication: Chicester
Language: eng
Number of pages: 223
ISBN-13: 9780470777800
Subjects: Disease susceptibility; Genetics; Etiology; Genetic Predisposition to Disease; Environmentally induced diseases; Congresses; Adverse effects; Disease Susceptibility; Environmental Exposure
Description: "Genetic Effects on Environmental Vulnerability to Disease is based on the final meeting of the Novartis Foundation Symposium Series (#293 Understanding How Gene Environment Interactions Work to Predict Disorder). Interwoven with transcripts of the lively discussions among researchers, the book offers a cutting-edge review of the methodological issues prevailing in this complex, multi-disciplinary field. A glossary is included to facilitate inter-disciplinary understanding, and Sir Michael Rutter's introduction and concluding remarks contribute to presenting scientific issues in an interesting, easily accessible manner." "This book will be of interest to epidemiologists, geneticists, developmental biologists, and researchers in psychiatric disorders, obesity, diabetes, cancer, respiratory diseases and cardiovascular disease."--BOOK JACKET.
Notes: Includes bibliographical references and indexes.
Table of contents: title: Introduction : whither gene-environment interactions? ? Michael Rutter; title: Gene-environment interaction : overcoming methodological challenges / Rudolf Uher; title: Gene-environment interaction and behavioral disorders : a developmental perspective based on endophenotypes / Marco Battaglia, Cecilia Marino, Michel Maziade, Massimo Molteni and Francesca D'Amato; title: Use of monozygotic twins to investigate the relationship between 5HTTLPR genotype, depression and stressful life events : an application of item response theory / Naomi R. Wray, William L. Coventry, Michael R. James, Grant W. Montgomery, Lindon J. Eaves and Nicholas G. Martin; title: Role of gene-stress interactions in gene finding studies / Harold Snieder, Xiaoling Wang, Vasiliki Lagou, Brenda W. J. H. Penninx, Harriëtte Riese and Catharina A. Hartman; title: Practice and public policy in the era of gene-environment interactions / Kenneth A. Dodge; title: Gene-environment interaction and the metabolic syndrome / Kristi B. Adamo and Frédérique Tesson; title: Longitudinal studies of gene-environment interaction in common diseases - good value for money? / Stephen P. Robertson and Richie Poulton; title: Gene-environment interactions in breast cancer / Kee-Seng Chia; title: Unbiased forward genetics and systems biology approaches to understanding how gene-environment interactions work to predict susceptibility and outcomes of infections / Malak Kotb, Nourtan Fathey, Ramy Aziz, Sarah Rowe, Robert W. Williams and Lu Lu; title: Gene-environment interactions in environmental lung diseases / Steven R. Kleeberger and Hye-Youn Cho; title: Gene-environment interaction in complex diseases : asthma as an illustrative case / Fernando D. Martinez; title: Conclusions : taking stock and looking ahead / Michael Rutter.