In silico technologies in drug target identification and validation
By: edited by Darryl León, Scott Markel.
Contributors: León, Darryl.; Markel, Scott.
Series: Drug discovery series -- 6
Publisher: CRC Press
Published: 2006
Place of publication: Boca Raton
Language: eng
Number of pages: 490
Subjects: Drug Delivery Systems -- methods; Chemistry, Pharmaceutical; Computational Biology
Notes: Includes bibliographical references and index.

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Table of contents: title: Pattern matching / Scott Markel and Vinodh N. Rajapakse; title: Tools for computational protein annotation and function assignment / Jaume M. Canaves; title: The impact of genetic variation on drug discovery and development / Michael R. Barnes; title: Mining of gene-expression data / Aedin Culhane and Alvis Brazma; title: Text mining / Bruce Gomes, William Hayes, and Raf M. Podowski; title: Pathways and networks / Eric Minch and Ivayla Vatcheva; title: Molecular interactions: learning from protein complexes / Ana Rojas, David de Juan and Alfonso Valencia; title: In silico siRNA design / Darryl León; title: Predicting protein subcellular localization using intelligent systems / Rajesh Nair and Burkhard Rost; title: The third-dimensional structures in target discovery and validation / Seán I. O'Donoghue, Robert B. Russell, and Andrea Schafferhans; title: Comparative genomics / Viviane Siino, Bruce Pascal, and Christopher Sears; title: Pharmacogenomics / Bahram Ghaffarzadeh Kermani; title: Target identification and validation using human simulation models / Seth Michelson, Didier Scherrer, and Alex L. Bangs; title: Using protein targets for in silico structure-based drug discovery / Tad Hurst; title: Database management / Arek Kasprzyk, and Damian Smedley; title: BioIT hardware configuration / Philip Miller; title: BioIT architecture: Software architecture for bioinformatics research / Michael Dickson; title: Workflows and data pipelines / Mike Peeler; title: Ontologies / Robin A. McEntire and Robert Stevens.