Genetic Hearing Loss
Publisher: Marcel Dekker
Published: September 1, 2003
Language: eng
Format: Hardcover
Number of pages: 483
ISBN-13: 9780824743093
Subjects: Audiology & otology; Otolaryngology; Hearing Loss; Medical / Nursing; Medical; congenital; Audiology & Speech Pathology; Medical / Otorhinolaryngology; Genetic aspects; Deafness; genetics
First sentence: The development of the normal ear is an extremely complex process, owing to the diversity of tissues and cells that are present in the ear compared to some other organs.
Description: Describes the normal development of the ear; updates the classification and epidemiology of hearing loss; surveys the usage of audiometric tests and diagnostic medical examinations; illuminates the most important syndromes associated with hearing loss such as Usher, Pendred, and Waardenburg syndromes; discusses the maternal inheritance patterns of mitochondrial hearing loss; provides a roadmap to gene localization and isolation in nonsyndromic hearing loss, exploring connexins, tectorins, myosins, ion channels, and other disease genes; highlights otosclerosis, one of the most common types of hearing loss; considers mechanisms regulating hair cell differentiation and regeneration; and elucidates the future of genetic testing for hearing loss.