Effects of lingual nerve damage on orofacial nociceptive reflexes.
Published: 2006
Language: eng
Number of pages: 176
ISBN-13: 9780494210994
Description: Results/conclusions. A nociceptive orofacial reflex exhibiting high MAT and co-activation of jaw-opening/closing and tongue muscles consistent with prior nociceptive chemical irritant studies was developed. Acute central sensitization can be induced by surgery and transection of the LN. NMS-evoked nociceptive orofacial reflexes may be useful in assessing small fiber nociceptive afferent input, which in turn may be useful in evaluating dysaesthesia and peripheral nerve damage.Purpose. Determine the effects of noxious mechanical stimulation (NMS) on four craniofacial sites by examining reflexively evoked orofacial EMG activity and to assess the effects of acute lingual nerve (LN) transection on these NMS-evoked reflexes.Acknowledgements. Supported by CIHR MOP-43905 and the Canadian Association of Oral & Maxillofacial Surgeons (CAOMS) foundation for continuing research grant.Methods. Orofacial reflexes in 31 adult male Sprague-Dawley rats divided into Control, SHAM and Transection groups were acutely evaluated under halothane-anaesthesia. NMS was delivered via a calibrated forceps to four specific craniofacial sites. EMG responses were evaluated using mechanical activation thresholds (MAT), area under the curve (AUC) and response durations (DUR).
Notes: Source: Masters Abstracts International, Volume: 45-03, page: 1442.

Thesis (M.Sc.)--University of Toronto, 2006.

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