Techniques in Animal Cytogenetics
By: edited by Paul Popescu, Helene Hayes, Bernard Dutrillaux
Contributors: Hayes, Helene; Dutrillaux, Bernard
Series: Principles and Practice; Principles and practice
Publisher: Springer Berlin Heidelberg
Published: 2000
Place of publication: Berlin, Heidelberg
Language: eng
Format: [electronic resource] /
Number of pages: 230
ISBN-13: 9783642640957; 9783642597114
Subjects: Biochemistry; Life sciences; Cytology; Human physiology; Human genetics
Description: The theoretical background of cytogenetics as well as the practical methods to investigate chromosomes from Drosophila to mammals and humans are presented in this book. Theory and practical protocols on the following topics are included: Cell culture methods, chromosome preparation and banding techniques, radioactive and fluorescent in situ hybridisation (FISH) methods and their derivates (chromosome painting), meiotic chromosome methods using light and electronic microscopy, the polytenic (Drosophila) and lampbrush (urodeles) chromosomes as well as flow and slit scan cytometry. The editors, all at INRA, played a prominent part in the development of cytogenetics. Paul Popescu, a specialist for domestic animals worked with gene mapping, Helene Hayes, together with Popescu showed the homology of bovine and human chromosome disorders, and Bernard Dutrilaux focused on human cytogenetics.
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