Acute effects of controlled exposure to concentrated particles with/without added ozone on heart rate variability.
Published: 2004
Language: eng
Number of pages: 118
Description: Epidemiological studies have shown that exposures to air pollution are associated with increased cardiorespiratory morbidity and mortality in susceptible people. The exact mechanism is poorly understood.Independent of exposure type for SDNN and WBF there were trends to decrease at the beginning of the exposure, between the 10-min and 20-min time points, and a tendency to increase towards the last 20 min of the exposure. Analysis of variance associated with the split-plot design, used to assess the size of the CAP effect, the O3 effect and their interaction, showed no significant differences for any HRV domain (p > 0.28).The effects of concentrated ambient particles (CAP) with/without added ozone (O3) on heart rate variability (HRV) were studied in six healthy non-asthmatics and four mild asthmatics, aged 21--34 years. Each subject was exposed to: (1) HEPA-filtered air (FA); (2) low CAP (60 mug/m3); and (3) high CAP (150 mug/m3), on three separate occasions.The responses observed in 6 young healthy subjects and 4 mild asthmatics at levels up to 185 mug/m3 CAP and 132 ppb O3 suggest no significant acute effects on analyzed domains of HRV. (Abstract shortened by UMI.)
Notes: Thesis (M.Sc.)--University of Toronto, 2004.

Electronic version licensed for access by U. of T. users.

Source: Masters Abstracts International, Volume: 42-06, page: 2185.

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