Kinase inhibitor drugs
By: Rongshi Li, Jeffrey A. Stafford.
Contributors: Stafford, Jeffrey A.
Publisher: J. Wiley
Published: 2009
Place of publication: Hoboken, N.J
Language: eng
ISBN-13: 9780470278291
Subjects: Protein kinases -- Inhibitors -- Therapeutic use; Antineoplastic agents; Neoplasms -- drug therapy; Protein Kinase Inhibitors -- therapeutic use; Antineoplastic Agents -- therapeutic use; Drug Discovery; Protein Kinase Inhibitors -- pharmacology; Protein Kinases -- metabolism
Notes: Includes index.
Table of contents: title: The discovery and development of sunitinib (SU11248); title: Tykerb discovery : a dual EGFR and erbB2 tyrosine kinase inhibitor; title: Discovery of pazopanib, a potent pan vascular endothelial growth factor inhibitor in clinical development; title: The road to ABT-869, a multi-targeted receptor tyrosine kinase inhibitor; title: Discovery of motesanib; title: The discovery of brivanib alaninate, a dual vascular endothelial growth factor and fibroblast growth factor receptor inhibitor; title: Structure-based design and characterization of axitinib; title: The road to PD0325901 and beyond : the MEK inhibitors quest; title: The discovery of allosteric MEK inhibitors; title: The discovery of MK-0457 (VX-680); title: Discovery of PHA-739358; title: The discovery of AZD1152 : a selective inhibitor of aurora B kinase with potent anti-tumor activity; title: Case study of aurora A inhibitor MLN8054; title: The discovery of GSK461364a; title: Pharmacogenomics of dasatinib; title: Practical use of computational chemistry in kinase drug discovery; title: Approaches to kinase homology modeling : successes and consideration for the structural kinome; title: Fragment-based drug discovery of kinase inhibitors; title: Protein kinase structural biology : methods and strategies for targeted drug discovery.