Molecular mechanisms of p53 functional inactivation
By: a thesis presented by Dmitri Wiederschain
Published: 2003
Language: eng
Number of pages: 173
Subjects: P53 protein; Genetic transcription
Notes: Thesis (Ph. D., Committee on Biological Sciences in Public Health)--Harvard University, 2003.

Includes bibliographical references.
Table of contents: title: Includes seven offprints (1-4) :; title: Evidence for a distinct inhibitory factor in the regulation of p53 functional activity -- (Journal of biological chemistry, v. 276:30, 2001, pp. 27999-28005); title: Molecular basis of p53 functional inactivation by the leukemic protein MLL-ELL -- (Molecular and cellular biology, v. 23:12, 2003, pp. 4230-4246); title: Mechanism of functional inactivation of a Li-Fraumeni syndrome p53 that has a mutation outside of the DNA-binding domain -- (Cancer research, v. 61, 2001, pp. 1741-1746); title: Identification of p53 sequence elements that are required for MDM2-mediated nuclear export-- (Molecular and cellular biology, v. 21:24, 2001, pp. 8533-8546); title: Includes seven offprints (5-7) :; title: Critical contribution of the MDM2 acidic domain to p53 ubiquitin  -- Hidehiko Kawai, Bmitri Wiederschain, and Zhi-Min Yuan -- (Molecular and cellular biology, v. 23:14, 2003, pp. 4939-4947); title: Mutual dependence of MDM2 and MDMX in their functional inactivation of p53 -- (Journal of biological chemistry, v. 277:22, 2002, pp. 19251-19254); title: Dual role of p300 in the regulation of p53 stability-- (Journal of biological chemistry, v. 276:49, 2001, pp. 45928-45932)