Neurobiology of Huntington's disease
Subtitle: applications to drug discovery
By: edited by Donald C. Lo and Robert E. Hughes.
Contributors: Lo, Donald C.; Hughes, Robert E., Ph.D.
Series: Frontiers in neuroscience; Frontiers in neuroscience (Boca Raton, Fla.)
Publisher: CRC Press/Taylor & Francis Group
Published: 2010
Place of publication: Boca Raton
Language: eng
ISBN-13: 9780849390005
Subjects: Huntington's chorea -- Pathophysiology; Huntington's chorea -- Molelcular aspects; Neuropharmacology; Huntington Disease -- physiopathology; Drug Discovery -- methods; Huntington Disease -- drug therapy
Notes: Includes bibliographical references and index.
Table of contents: title: Huntington's disease : clinical features and routes to therapy / Henry L. Paulson and Roger L. Albin; title: Huntington's disease pathogenesis : mechanisms and pathways / Albert R. La Spada, Patrick Weydt, and Victor V. Pineda; title: Protein interactions and target discovery in HD / John P. Miller and Robert E. Hughes; title: Target validation for Huntington's disease / Seung P. Kwak, James K.T. Wang, and David S. Howland; title: High-throughput and high-content screening for Huntington's disease therapeutics / Hemant Varma, Donald C. Lo, and Brent R. Stockwell; title: Value of invertebrate genetics and biology to develop neuroprotective and preventive medicine in Huntington's disease / Christian Neri; title: Mouse models for validating preclinical candidates for HD / X. William Yang and Michelle Gray; title: Pharmaceutical development for HD / Richard J. Morse ... [et al.]; title: RNA and DNA-based therapies for Huntington's disease / Meghan Sass and Neil Aronin; title: Recombinant intrabodies as molecular tools and potential therapeutics for Huntington's disease / Ali Khoshnan ... [et al.]; title: Biomarkers to enable the development of neuroprotective therapies for Huntington's disease / Steven M. Hersch and H. Diana Rosas; title: Huntington disease : clinical experimental therapeutics / Ray Dorsey and Ira Shoulson.