Principles of anticancer drug development
By: edited by Manuel Hidalgo ... [et al.].
Series: Cancer drug discovery and development; Cancer drug discovery and development
Publisher: Springer
Published: 2011
Place of publication: New York
Language: eng
Number of pages: 673
ISBN-13: 9781441973573; 9781441973580
Subjects: Methods; Drug development; Neoplasms; Drug Discovery; Antineoplastic Agents; Drug therapy; Therapeutic use; Clinical Trials as Topic; Antineoplastic agents; Drug Approval
Notes: Includes bibliographical references and index.
Table of contents: title: Basic biostatistics for the clinical trialist / Elizabeth G. Hill and Elizabeth Garrett-Mayer; title: Fundamental concepts in clinical pharmacology / Daniel L. Gustafson and Erica L. Bradshaw-Pierce; title: Bioanalycial methods in clinical drug development / Walter J. Loos, Peter de Bruijn and Alex Sparreboom; title: Preclinical models for anticancer drug development / Edward A. Sausville; title: Phase I clinical trials with anticancer agents / Stephen Leong ... [et al.]; title: Phase II trials with anticancer agents / Hui K. Gan, J. Jack Lee and Lillian L. Siu; title: Phase III clinical trials with anticancer agents / Wendy R. Parulekar and Daniel J. Sargent; title: Pharmacokinetic studies in early anticancer drug development / Alex Sparreboom and Sharyn D. Baker; title: Pharmacodynamic studies in early phase drug development / D. Ross Camidge, Robert C. Doebele and Antonio Jimeno; title: Prediction of antitumor response / Fred R. Hirsch and Yu Shyr; title: Imaging studies in anticancer drug development / David A. Mankoff; title: Role of the U.S. Food and drug administration in cancer drug development / Ann T. Farrell, Ramzi N. Dagher and Richard Pazdur; title: Early clinical trials with cytotoxic agents / M.J.A. de Jonge and Jaap Verweij; title: Challenges and successes in developing effective anti-angiogenic agents / Laura Q.M. Chow and S. Gail Eckhardt; title: Targeted therapeutics in cancer treatment / Colin D. Weekes and Manuel Hidalgo; title: Cancer chemoprevention / Christopher H. Lieu, William N. William Jr. and Scott Lippman; title: Combined modality therapy in cancer management / David Raben and Kyle Rusthoven; title: Cancer vaccines / Daniel Laheru; title: Optimising the development of antibodies as treatment for cancer / Craig P. Carden, Hendrik-Tobias Arkenau and Johann S. de Bono; title: Oligonucleotide therapeutics / Cy A. Stein, Britta Hoehn and John Rossi; title: Anticancer drug development in pediatric patients / Lia Gore and Margaret Macy; title: Clinical trials in special populations / S. Percy Ivy ... [et al.]; title: NCI-sponsored clinical trials / Andriana Papaconstantinou and Janet E. Dancey.