Function and Regulation of Cellular Systems
By: edited by Andreas Deutsch, Jonathon Howard, Martin Falcke, Walter Zimmermann
Contributors: Howard, Jonathon; Falcke, Martin; Zimmermann, Walter
Series: Mathematics and Biosciences in Interaction; Mathematics and biosciences in interaction
Publisher: Birkhäuser Basel; Imprint: Birkhäuser
Published: 2004
Place of publication: Basel
Language: eng
Format: [electronic resource] /
Number of pages: 451
ISBN-13: 9783034896146; 9783034878951
Subjects: Biology; Computer simulation; Data processing; Mathematics; Physiology; Systems theory
Description: Current biological research demands more and more the extensive use of sophisticated mathematical methods and computer-aided analysis of experiments and data. Mathematical analysis reveals similarities and differences in organization principles of metabolic, signaling and cellular interaction networks. This highly interdisciplinary book focuses on structural, dynamical and functional aspects of cellular systems and presents corresponding experiments and mathematical models. It may serve as an introduction for biologists, mathematicians and physicists to key questions in cellular systems which can be studied with mathematical models. Recent model approaches are presented with applications in cellular metabolism, intra- and intercellular signaling, cellular mechanics, network dynamics and pattern formation. In addition, applied issues as tumor cell growth, dynamics of the immune system and biotechnology are included. The book is based on selected peer-reviewed contributions and discussions at the "1. International MTBio workshop on function and regulation of cellular systems: experiments and models" (Dresden, June 24-30, 2001). The international competence and information network MTBio (Modeling and Theory in the Biosciences, www.mtbio.de) has been recently founded to improve communication between experimentalists and theoreticians sharing interests in the application of mathematical models.
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Table of contents: title: From the contents: Metabolic Networks and Engineering; title: Intracellular Signal Transduction; title: Cellular Materials: Mechanics and Motility; title: Complex Network Dynamics in Biological Cells; title: Interacting Cell Systems; title: How Cells Construct an Organism: Experiments and Modelling; title: Tumors, Diseases and the Immune System.