Cell Immortalization (Progress in Molecular and Subcellular Biology)
Edition: 1st edition
Publisher: Springer
Published: November 15, 1999
Language: eng
Format: Hardcover
Number of pages: 213
ISBN-13: 9783540656180
Subjects: Biochemistry; Cellular biology; Cellular physiology; Science/Mathematics; Cytology; Science; Life Sciences - Cytology; Oncology; Medical-Oncology; Science / Cytology; Apoptosis; Cell proliferation
Description: [Publisher-supplied data] This book describes the most outstanding theoretical hypotheses aiming at explaining the infinite proliferative potential of a cell population, what is now known under the term cell immortalization. It elucidates the phenomenon from an evolutionary point of view, and describes the cell systems used and the experiments performed at the cellular and molecular levels to determine the mechanisms responsible for this cell property. It also appraises how the mortal and immortal phenotypes reflect characteristics of the respective organism, and stresses how this goes beyond the proposal that its opposite, the mortal phenotype, is a mechanism to protect the organism against cancer.