The Role of TSC in Oligodendrocyte Differentiation and Myelination
Contributors: Stevens, Beth; Nishiyama, Akiko; Gu, Chenghua; Ma, Qiufu
Published: 2012
Language: eng
Description: Tuberous Sclerosis Complex (TSC) is an autosomal dominant syndrome characterized by epilepsy, intellectual disability, and autism. Recent studies have suggested that white matter abnormalities, including hypomyelination, contribute to the cognitive deficits in TSC patients, but the mechanism has remained elusive.
Notes: Keywords: autism, CTGF, myelin, oligodendrocytes, TSC.

Thesis Ph.D. Harvard University 2012