Technetium-99m radiopharmaceuticals
Subtitle: manufacture of kits
Series: Technical reports series -- no. 466
Publisher: International Atomic Energy Agency
Published: 2008
Place of publication: Vienna
Language: eng
Number of pages: 189
ISBN-13: 9789201004086
Subjects: Radiopharmaceutical industry; Radiopharmaceuticals; Therapeutic use; Quality control; Technetium
Description: This report describes the procedures for preparing 23 selected Tc-99m radiopharmaceutical kits. Details of the preparation of ten of the active ingredients are also included. The procedures described here can be used to develop manuals, monographs and standard operating procedures. This report is expected to serve as a guide to radiopharmaceutical manufacturing centers and centralized pharmacies involved in the production of kits, and to be a useful resource for the many hospital radiopharmacies that routinely use the kits to compound Tc-99m radiopharmaceuticals, and a source of information for regulators of radiopharmaceuticals.--Publisher's description.
Notes: "STI/DOC/010/466."

Includes bibliographical references.

Available both in print and online.
Table of contents: title: Introduction; title: Technetium chemistry : the state of the art; title: Good manufacturing practice; title: General procedures for production of kits; title: General procedures in quality control; title: Production methods and specific actions; title: Synthesis of active ingredients.